Phenotypic analysis of meltrin α (ADAM12)-deficient mice: Involvement of meltrin α in adipogenesis and myogenesis

Molecular and Cellular Biology

Volumn 23, Issue 1, 2003, Pages 55-61

  Kurisaki, Tomohiro ^a   Masuda, Aki ^a   Sudo, Katsuko ^b   Sakagami, Junko ^b   Higashiyama, Shigeki ^c   Matsuda, Yoichi ^d,e   Nagabukuro, Akira ^e   Tsuji, Atsushi ^e   Nabeshima, Yoichi ^f   Asano, Masahide ^g   Iwakura, Yoichiro ^b   Sehara Fujisawa, Atsuko ^a  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d HOKKAIDO UNIVERSITY   (Japan)

^e NAGOYA UNIVERSITY   (Japan)

^f KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM12 PROTEIN; DISINTEGRIN; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MELTRIN ALPHA; METALLOPROTEINASE; PHORBOL 13 ACETATE 12 MYRISTATE; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; CELL VIABILITY; CHROMOSOME MAP; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GENE TARGETING; HOMOZYGOSITY; LIPOGENESIS; MOUSE; MOUSE STRAIN; MUSCLE DEVELOPMENT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEFECT; PROTEIN DOMAIN; RAT;

ADAM PROTEINS; ADIPOSE TISSUE; ANIMALS; ANIMALS, NEWBORN; CHROMOSOME MAPPING; EMBRYO; EPIDERMAL GROWTH FACTOR; FIBROBLASTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MEMBRANE PROTEINS; MICE; MICE, MUTANT STRAINS; MUSCLE PROTEINS; MUSCLE, SKELETAL; PHENOTYPE; RATS; REGENERATION; TETRADECANOYLPHORBOL ACETATE;

ANIMALIA; MAMMALIA;

EID: 0037214312     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.1.55-61.2003     Document Type: Article

References (48)

1. Asakura, M., M. Kitakaze, S. Takashima, Y. Liao, F. Ishikura, T. Yoshinaka, H. Ohmoto, K. Node, K. Yoshino, H. Ishiguro, H. Asanuma, S. Sanada, Y. Matsumura, H. Takeda, S. Beppu, M. Tada, M. Hori, and S. Higashiyama. 2002. Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy. Nat. Med. 8:35-40.
2. Black R. A., C. T. Rauch, C. J. Kozlosky, J. J. Peschon, J. L. Slack, M. F. Wolfson, B. J. Castner, K. L. Stocking, P. Reddy, S. Srinivasan, N. Nelson, N. Boiani, K. A. Schooley, M. Gerhart, R. Davis, J. N. Fitzner, R. S. Johnson, R. J. Paxton, C. J. March, and D. P. Cerretti. 1997. A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature 385:729-733.
3. Black, R. A., and J. M. White. 1998. ADAMs: Focus on the protease domain. Curr. Opin. Cell Biol. 10:654-659.
4. Blobel, C. P., T. G. Wolfsberg, C. W. Turck, D. G. Myles, P. Primakoff, and J. M. White. 1992. A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion. Nature 356:248-252.
5. Borneman, A., R. Kuschel, and A. Fujisawa-Sehara. 2000. Analysis for transcript expression of meltrin alpha in normal, regenerating, and denervated rat muscle. J. Muscle Res. Cell Motil. 21:475-480.
6. 1. J. Biol. Chem. 277:3784-3792.
7. Buxbaum, J. D., K. N. Liu, Y. Luo, J. L. Slack, K. L. Stocking, J. J. Peschon, R. S. Johnson, B. J. Castner, D. P. Cerretti, and R. A. Black. 1998. Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor. J. Biol. Chem. 273:27765-27767.
8. Cho, C., D. O. Bunch, J. E. Faure, E. H. Goulding, E. M. Eddy, P. Primakoff, and D. G. Myles. 1998. Fertilization defects in sperm from mice lacking Fertilin β. Science 281:1857-1859.
9. Dangain, J., and G. Vrbova. 1984. Muscle development in mdx mutant mice. Muscle Nerve 7:700-704.
10. Eto, K., W. Puzon-McLaughlin, D. Sheppard, A. Sehara-Fujisawa, X. P. Zhang, and Y. Takada. 2000. RGD-independent binding of integrin alpha9beta1 to the ADAM-12 and -15 disintegrin domains mediates cell-cell interaction. J. Biol. Chem. 275:34922-34930.
11. Florini, J. R., D. Z. Ewton, and S. A. Coolican. 1996. Growth hormone and the insulin-like growth factor system in myogenesis. Endocrinol. Rev. 17:481-517.
12. Gilpin, B. J., F. Loechel, M. G. Mattei, E. Engvall, R. Albrechtsen, and U. M. Wewer. 1998. A novel, secreted form of human ADAM 12 (Meltrin α) provokes myogenesis in vivo. J. Biol. Chem. 273:157-166.
13. Goishi, K., S. Higashiyama, M. Klagsbrun, M. Ishikawa, E. Mekada, and N. Taniguchi. 1995. Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: Conversion from juxtacrine to paracrine growth factor activity. Mol. Biol. Cell 6:967-980.
14. Hogan, B., R. Beddington, F. Costantini, and E. Lacy. 1994. Manipulating the Mouse Embryo: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
15. Iba, K., R. Albrechtsen, B. Gilpin, C. Frohlich, F. Loechel, A. Zolkiewska, K. Ishiguro, T. Kojima, W. Liu, J. K. Langford, R. D. Sanderson, C. Brakebusch, R. Fassler, and U. M. Wewer. 2000. The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading. J. Cell Biol. 149:1143-1156.
16. Kawaguchi, N., X. Xu, R. tajima, P. Kronqvist, C. Sundberg, F. Loechel, R. Albrechtsen, and U. M. Wewer. 2002. ADAM 12 protease induces adipogenesis in transgenic mice. Am. J. Pathol. 160:1895-1903.
17. Kurisaki, T., A. Masuda, N. Osumi, Y. Nabeshima, and A. Fujisawa-Sehara. 1998. Spatially- and temporally-restricted expression of meltrin α (ADAM12) and β (ADAM19) in mouse embryo. Mech. Dev. 73:211-215.
18. Lieber, T., S. Kidd, and M. W. Young. 2002. Kuzbanian-mediated cleavage of Drosophila Notch. Genes Dev. 16:209-221.
19. Loechel, F., J. W. Fox, G. Murphy, R. Albrechtsen, and U. M. Wewer. 2000. ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3. Biochem. Biophys. Res. Commun. 278:511-515.
20. Lyon, M. F., Y. Cocking, and X. Gao. 1996. Mouse chromosome atlas. Mouse Genome 95:731-798.
21. Matsuda, Y., Y. N. Harada, S. Natsuume-Sakai, K. Lee, T. Shiomi, and V. M. Chapman. 1992. Location of the mouse complement factor H gene (cfh) by FISH analysis and replication R-banding. Cytogenet. Cell Genet. 61:282-285.
22. Matsuda, Y., T. Imai, T. Shiomi, T. Saito, M. Yamauchi, T. Fukao, Y. Akao, N. Seki, H. Ito, and T. A. Hori. 1996. Comparative genome mapping of the ataxia-telangiectasia region in mouse, rat, and Syrian hamster. Genomics 34:347-352.
23. Moss, M. L., S. L. Jin, M. E. Milla, D. M. Bickett, W. Burkhart, H. L. Carter, W. J. Chen, W. C. Clay, J. R. Didsbury, D. Hassler, C. R. Hoffman, T. A. Kost, M. H. Lambert, M. A. Leesnitzer, P. McCauley, G. McGeehan, J. Mitchell, M. Moyer, G. Pahel, W. Rocque, L. K. Overton, F. Schoenen, T. Seaton, J. L. Su, J. D. Becherer, et al. 1997. Cloning of a disintegrin metalloproteinase that processes precursor tumour necrosis factor-alpha. Nature 385:733-736.
24. Musaro, A., K. McCullagh, A. Paul, L. Houghton, G. Dobrowolny, M. Molinaro, E. R. Barton, H. L. Sweeney, and N. Rosenthal. 2001. Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle. Nat. Genet. 27:195-200.
25. Musaro, A., K. J. McCullagh, F. J. Naya, E. N. Olson, and N. Rosenthal. 1999. IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1. Nature 400:581-585.
26. Nagy, A., J. Rossant, R. Nagy, W. Abramow-Newerly, and J. C. Roder. 1993. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc. Natl. Acad. Sci. USA 90:8424-8428.
27. 1 integrin, leading to a marked induction of fibroblast cell motility. J. Cell Sci. 113(Pt. 12):2319-2328.
28. Pan, D., and G. M. Rubin. 1997. Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis. Cell 90:271-280.
29. Pittenger, M. F., A. M. Mackay, S. C. Beck, R. K. Jaiswal, R. Douglas, J. D. Mosca, M. A. Moorman, D. W. Simonetti, S. Craig, and D. R. Marshak. 1999. Multilineage potential of adult human mesenchymal stem cells. Science 284:143-147.
30. Primakoff, P., and D. G. Myles. 2000. The ADAM gene family: Surface proteins with adhesion and protease activity. Trends Genet. 16:83-87.
31. Qi, H., M. D. Rand, X. Wu, N. Sestan, W. Wang, P. Rakic, T. Xu, and S. Artavanis-Tsakonas. 1999. Processing of the Notch ligand delta by the metalloprotease Kuzbanian. Science 283:91-94.
32. Rosen, E. D., and B. M. Spiegelman. 2000. Molecular regulation of adipogenesis. Annu. Rev. Cell Dev. Biol. 16:145-171.
33. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
34. Satoh, H., M. C. Yoshida, and M. Sasaki. 1989. High resolution chromosome banding in the Norway rat, Rattus norvegicus. Cytogenet. Cell Genet. 50:151-154.
35. Schlondorff, J., and C. P. Blobel. 1999. Metalloprotease-disintegrins: Modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding. J. Cell Sci. 112(Pt. 21):3603-3617.
36. Shi, Z., W. Xu, F. Loechel, U. M. Wewer, and L. J. Murphy. 2000. ADAM 12, a disintegrin metalloprotease, interacts with insulin-like growth factor-binding protein-3. J. Biol. Chem. 275:18574-18580.
37. Shirakabe, K., S. Wakatsuki, T. Kurisaki, and A. Fujisawa-Sehara. 2001. Roles of Meltrin β/ADAM19 in the processing of neuregulin. J. Biol. Chem. 276:9352-9358.
38. Somssich, I. E., and H. Hameister. 1996. Standard karyotype of early replicating bands (RBG-banding), p. 1450-1451. In M. F. Lyon, S. Rastan, and S. D. M. Brown (ed.), Genetic Variants and Strains of the Laboratory Mouse. Oxford University Press, Oxford, England.
39. Soriano, P., C. Montgomery, R. Geske, and A. Bradley. 1991. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64:693-702.
40. Sotillos, S., F. Roch, and S. Campuzano. 1997. The metalloprotease-disintegrin Kuzbanian participates in Notch activation during growth and patterning of Drosophila imaginal discs. Development 124:4769-4779.
41. Stedman, H. H., H. L. Sweeney, J. B. Shrager, H. C. Maguire, R. A. Panettieri, B. Petrof, M. Narusawa, J. M. Leferovich, J. T. Sladky, and A. M. Kelly. 1991. The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy. Nature 352:536-539.
42. Taylor, S. M., and P. A. Jones. 1979. Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine. Cell 17:771-779.
43. Turner, A. J., and N. M. Hooper. 1999. Role for ADAM-family proteinases as membrane protein secretases. Biochem. Soc. Trans. 27:255-259.
44. Wolfsberg, T. G., P. Primakoff, D. G. Myles, and J. M. White. 1995. ADAM, a novel family of membrane proteins containing a disintegrin and metalloprotease domain: Multipotential functions in cell-cell and cell-matrix interactions. J. Cell Biol. 131:275-278.
45. Yagami-Hiromasa, T., T. Sato, T. Kurisaki, K. Kamijo, Y. Nabeshima, and A. Fujisawa-Sehara. 1995. A metalloprotease-disintegrin participating in myoblast fusion. Nature 377:652-656.
46. Yagi, T., S. Nada, N. Watanabe, H. Tamemoto, N. Kohmura, Y. Ikawa, and S. Aizawa. 1993. A novel negative selection for homologous recombinants using diphtheria toxin A fragment gene. Anal. Biochem. 214:77-86.
47. Yamada, J., T. Kuramoto, and T. Serikawa. 1994. A rat genetic linkage map and comparative maps for mouse or human homologous rat genes. Mamm. Genome 5:63-83.
48. 5 integrin. Biochem. Biophys. Res. Commun. 280:574-580.