Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair

EMBO Journal

Volumn 27, Issue 23, 2008, Pages 3140-3150

  Chou, Wen Cheng ^a,b   Wang, Hui Chun ^b,c   Wong, Fen Hwa ^a   Ding, Shian Ling ^d   Wu, Pei Ei ^b,e   Shieh, Sheau Yann ^b   Shen, Chen Yang ^b,e,f  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d Kang Ning Junior College of Medical Care and Management   (Taiwan)

^e ACADEMIA SINICA   (Taiwan)

^f CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

ATM; BER; Chk2; DNA damage response; XRCC1

Indexed keywords

ATM PROTEIN; CHECKPOINT KINASE 2; CHECKPOINT KINASE RAD3; DNA GLYCOSYLTRANSFERASE; SMALL INTERFERING RNA; XRCC1 PROTEIN;

ARTICLE; CANCER RISK; CELL STRAIN MCF 7; COMET ASSAY; CONTROLLED STUDY; DNA ALKYLATION; DNA DAMAGE; DNA STRAND BREAKAGE; EXCISION REPAIR; GENOMIC INSTABILITY; HELA CELL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MUTATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

ALKYLATING AGENTS; CELL LINE, TUMOR; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; OXIDANTS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES;

ATAXIA TELANGIECTASIA;

EID: 57149112500     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2008.229     Document Type: Article

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