Therapeutic benefits of intrathecal protein therapy in a mouse model of amyotrophic lateral sclerosis

Journal of Neuroscience Research

Volumn 86, Issue 13, 2008, Pages 3028-3037

  Ohta, Yasuyuki ^a   Kamiya, Tatsushi ^a   Nagai, Makiko ^a   Nagata, Tetsuya ^a   Morimoto, Nobutoshi ^a   Miyazaki, Kazunori ^a   Murakami, Tetsuro ^a   Kurata, Tomoko ^a   Takehisa, Yasushi ^a   Ikeda, Yoshio ^a   Asoh, Sadamitsu ^b   Ohta, Shigeo ^b   Abe, Koji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b Graduate School of Medicine   (Japan)

Author keywords

ALS; Bcl 2; SOD1; Spinal cord; TAT

Indexed keywords

ADENINE; CASPASE 3; CASPASE 9; COPPER ZINC SUPEROXIDE DISMUTASE; GUANINE; PROTEIN BCL XL; TRANSACTIVATOR PROTEIN;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; ENZYME DEGRADATION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; LUMBAR SPINAL CORD; MALE; MOTONEURON; MOTOR PERFORMANCE; MOUSE; MUTATIONAL ANALYSIS; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; SPINAL CORD NERVE CELL; SURVIVAL TIME; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; APOPTOSIS; BCL-X PROTEIN; DISEASE MODELS, ANIMAL; GENE PRODUCTS, TAT; HUMANS; IN SITU NICK-END LABELING; INJECTIONS, SPINAL; MICE; MICE, TRANSGENIC; MOTOR NEURONS; SPINAL CORD;

EID: 57049109232     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21747     Document Type: Article

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