-
1
-
-
33847345059
-
-
Markovic, S.N., Erickson, L.A., Rao, R.D. et al. Malignant melanoma in the 21st century, part 1: Epidemiology, risk factors, screening, prevention, and diagnosis. Mayo Clin Proc 2007, 82(3): 364-80.
-
Markovic, S.N., Erickson, L.A., Rao, R.D. et al. Malignant melanoma in the 21st century, part 1: Epidemiology, risk factors, screening, prevention, and diagnosis. Mayo Clin Proc 2007, 82(3): 364-80.
-
-
-
-
2
-
-
33751114201
-
Incidence, mortality and survival in cutaneous melanoma
-
Giblin, A.V., Thomas, J.M. Incidence, mortality and survival in cutaneous melanoma. J Plast Reconstr Aesthet Surg 2007, 60(1): 32-40.
-
(2007)
J Plast Reconstr Aesthet Surg
, vol.60
, Issue.1
, pp. 32-40
-
-
Giblin, A.V.1
Thomas, J.M.2
-
3
-
-
16844385347
-
Melanoma genetics and the development of rational therapeutics
-
Chudnovsky, Y., Khavari, P.A., Adams, A.E. Melanoma genetics and the development of rational therapeutics. J Clin Invest 2005, 115(4): 813-24.
-
(2005)
J Clin Invest
, vol.115
, Issue.4
, pp. 813-824
-
-
Chudnovsky, Y.1
Khavari, P.A.2
Adams, A.E.3
-
4
-
-
33847220364
-
Melanoma biology and new targeted therapy
-
Gray-Schopfer, V., Wellbrock, C., Marais, R. Melanoma biology and new targeted therapy. Nature 2007, 445(7130): 851-7.
-
(2007)
Nature
, vol.445
, Issue.7130
, pp. 851-857
-
-
Gray-Schopfer, V.1
Wellbrock, C.2
Marais, R.3
-
5
-
-
34447115655
-
Angiogenesis and metastasis inhibitors for the treatment of malignant melanoma
-
Abe, R., Fujita, Y., Yamagishi, S. Angiogenesis and metastasis inhibitors for the treatment of malignant melanoma. Mini-Rev Med Chem 2007, 7(6): 649-61.
-
(2007)
Mini-Rev Med Chem
, vol.7
, Issue.6
, pp. 649-661
-
-
Abe, R.1
Fujita, Y.2
Yamagishi, S.3
-
6
-
-
33747661085
-
Update on immunotherapy for melanoma
-
Ribas, A. Update on immunotherapy for melanoma. J Natl Compr Cancer Netw 2006, 4(7): 687-94.
-
(2006)
J Natl Compr Cancer Netw
, vol.4
, Issue.7
, pp. 687-694
-
-
Ribas, A.1
-
7
-
-
32844469134
-
Posttranslational modifications of Bcl2 family members - A potential therapeutic target for human malignancy
-
Basu, A., DuBois, G., Haldar, S. Posttranslational modifications of Bcl2 family members - A potential therapeutic target for human malignancy. Front Biosci 2006, 11: 1508-21.
-
(2006)
Front Biosci
, vol.11
, pp. 1508-1521
-
-
Basu, A.1
DuBois, G.2
Haldar, S.3
-
8
-
-
33646262911
-
Molecular targets in melanoma from angiogenesis to apoptosis
-
Sosman, J.A., Puzanov, I. Molecular targets in melanoma from angiogenesis to apoptosis. Clin Cancer Res 2006, 12(7, Part 2): 2376s-83s.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.7 and PART 2
-
-
Sosman, J.A.1
Puzanov, I.2
-
9
-
-
27744449761
-
Bcl-2 overexpression in melanoma cells increases tumor progression-associated properties and in vivo tumor growth
-
Trisciuoglio, D., Desideri, M., Ciuffreda, L. et al. Bcl-2 overexpression in melanoma cells increases tumor progression-associated properties and in vivo tumor growth. J Cell Physiol 2005, 205(3): 414-21.
-
(2005)
J Cell Physiol
, vol.205
, Issue.3
, pp. 414-421
-
-
Trisciuoglio, D.1
Desideri, M.2
Ciuffreda, L.3
-
10
-
-
33747627127
-
The effect of imatinib mesylate (Glivec) on human tumor-derived cells
-
Knight, A.L., Di Nicolantonio, F., Whitehouse, A.P. et al. The effect of imatinib mesylate (Glivec) on human tumor-derived cells. Anti-Cancer Drugs 2006, 17(6): 649-55.
-
(2006)
Anti-Cancer Drugs
, vol.17
, Issue.6
, pp. 649-655
-
-
Knight, A.L.1
Di Nicolantonio, F.2
Whitehouse, A.P.3
-
11
-
-
33845285906
-
A sequential blockade strategy for the design of combination therapies to overcome oncogene addiction in chronic myelogenous leukemia
-
Chen, R., Gandhi, V., Plunkett, W. A sequential blockade strategy for the design of combination therapies to overcome oncogene addiction in chronic myelogenous leukemia. Cancer Res 2006, 66(22): 10959-66.
-
(2006)
Cancer Res
, vol.66
, Issue.22
, pp. 10959-10966
-
-
Chen, R.1
Gandhi, V.2
Plunkett, W.3
-
12
-
-
0030984895
-
A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation
-
Kwon, B.S., Tan, K. B., Ni, J. et al. A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation. J Biol Chem 1997, 272(22): 14272-6.
-
(1997)
J Biol Chem
, vol.272
, Issue.22
, pp. 14272-14276
-
-
Kwon, B.S.1
Tan, K.B.2
Ni, J.3
-
13
-
-
37249088549
-
Adjuvant effect of anti-4-1BB mAb administration in adoptive T cell therapy of cancer
-
Li, Q., Iuchi, T., Jure-Kunkel, M.N., Chang, A.E. Adjuvant effect of anti-4-1BB mAb administration in adoptive T cell therapy of cancer. Int J Biol Sci 2007, 3(7): 455-62.
-
(2007)
Int J Biol Sci
, vol.3
, Issue.7
, pp. 455-462
-
-
Li, Q.1
Iuchi, T.2
Jure-Kunkel, M.N.3
Chang, A.E.4
-
14
-
-
22944477731
-
Immunity to melanoma mediated by 4-1BB is associated with enhanced activity of tumour-infiltrating lymphocytes
-
Ju, S.A., Lee, S.C., Kwon, T.H. et al. Immunity to melanoma mediated by 4-1BB is associated with enhanced activity of tumour-infiltrating lymphocytes. Immunol Cell Biol 2005, 83(4): 344-51.
-
(2005)
Immunol Cell Biol
, vol.83
, Issue.4
, pp. 344-351
-
-
Ju, S.A.1
Lee, S.C.2
Kwon, T.H.3
-
15
-
-
27144458821
-
CTLA-4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction
-
Contardi, E., Palmisano, G.L., Tazzari, P.L. et al. CTLA-4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction. Int J Cancer 2005, 117(4): 538-50.
-
(2005)
Int J Cancer
, vol.117
, Issue.4
, pp. 538-550
-
-
Contardi, E.1
Palmisano, G.L.2
Tazzari, P.L.3
-
16
-
-
33644820365
-
CD28-mediated costimulation impacts on the differentiation of DC vaccination-induced T cell responses
-
Voigt, H., Schrama, D., Eggert, A.O. et al. CD28-mediated costimulation impacts on the differentiation of DC vaccination-induced T cell responses. Clin Exp Immunol 2006, 143(1): 93-102.
-
(2006)
Clin Exp Immunol
, vol.143
, Issue.1
, pp. 93-102
-
-
Voigt, H.1
Schrama, D.2
Eggert, A.O.3
-
17
-
-
34249709048
-
Down-regulation of the interferon signaling pathway in T lymphocytes from patients with metastatic melanoma
-
Critchley-Thorne, R.J., Yan, N., Nacu, S., Weber, J., Holmes, S.P., Lee, P.P. Down-regulation of the interferon signaling pathway in T lymphocytes from patients with metastatic melanoma. PLoS Med 2007, 4(5): e176.
-
(2007)
PLoS Med
, vol.4
, Issue.5
-
-
Critchley-Thorne, R.J.1
Yan, N.2
Nacu, S.3
Weber, J.4
Holmes, S.P.5
Lee, P.P.6
-
18
-
-
14844331767
-
Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2
-
Adamson, A.W., Beardsley, D.I., Kim, W.J., Gao, Y., Baskaran, R., Brown, K.D. Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2. Mol Biol Cell 2005, 16(3): 1513-26.
-
(2005)
Mol Biol Cell
, vol.16
, Issue.3
, pp. 1513-1526
-
-
Adamson, A.W.1
Beardsley, D.I.2
Kim, W.J.3
Gao, Y.4
Baskaran, R.5
Brown, K.D.6
-
19
-
-
33644510424
-
Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant
-
Kwak, E.L., Kim, S., Zhang, J., Cardiff, R.D., Schmidt, E.V., Haber, D.A. Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant. Cancer Res 2006, 66(4): 1923-8.
-
(2006)
Cancer Res
, vol.66
, Issue.4
, pp. 1923-1928
-
-
Kwak, E.L.1
Kim, S.2
Zhang, J.3
Cardiff, R.D.4
Schmidt, E.V.5
Haber, D.A.6
-
20
-
-
37249011051
-
Mutational analysis of Chk1, Chk2, Apaf1 and Rb1 in human malignant melanoma cell lines
-
Papp, T., Niemetz, A., Dosdahl, N., Kumar, K., Schiffmann, D. Mutational analysis of Chk1, Chk2, Apaf1 and Rb1 in human malignant melanoma cell lines. Oncol Rep 2007, 17(1): 135-40.
-
(2007)
Oncol Rep
, vol.17
, Issue.1
, pp. 135-140
-
-
Papp, T.1
Niemetz, A.2
Dosdahl, N.3
Kumar, K.4
Schiffmann, D.5
-
21
-
-
33644830944
-
Targeting the cell cycle: A new approach to cancer therapy
-
Schwartz, G.K., Shah, M.A. Targeting the cell cycle: A new approach to cancer therapy. J Clin Oncol 2005, 23(36): 9408-21.
-
(2005)
J Clin Oncol
, vol.23
, Issue.36
, pp. 9408-9421
-
-
Schwartz, G.K.1
Shah, M.A.2
-
22
-
-
33646528191
-
Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation
-
Berthet, C., Klarmann, K.D., Hilton, M.B., Suh, H.C., Keller, J.R., Kiyokawa, H., Kaldis, P. Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation. Dev Cell 2006, 10(5): 563-73.
-
(2006)
Dev Cell
, vol.10
, Issue.5
, pp. 563-573
-
-
Berthet, C.1
Klarmann, K.D.2
Hilton, M.B.3
Suh, H.C.4
Keller, J.R.5
Kiyokawa, H.6
Kaldis, P.7
-
23
-
-
0035092418
-
Expression of cyclins and cyclin dependent kinases in human benign and malignant melanocytic lesions
-
Georgieva, J., Sinha, P., Schadendorf, D. Expression of cyclins and cyclin dependent kinases in human benign and malignant melanocytic lesions. J Clin Pathol 2001, 54(3): 229-35.
-
(2001)
J Clin Pathol
, vol.54
, Issue.3
, pp. 229-235
-
-
Georgieva, J.1
Sinha, P.2
Schadendorf, D.3
-
24
-
-
0032772629
-
Expression of cell cycle regulators in human cutaneous malignant melanoma
-
Tang, L., Li, G., Tron, V.A., Trotter, M.J., Ho, V.C. Expression of cell cycle regulators in human cutaneous malignant melanoma. Melanoma Res 1999, 9(2): 148-54.
-
(1999)
Melanoma Res
, vol.9
, Issue.2
, pp. 148-154
-
-
Tang, L.1
Li, G.2
Tron, V.A.3
Trotter, M.J.4
Ho, V.C.5
-
25
-
-
33644856123
-
Epigenetic therapy of cancer: Past, present and future
-
Yoo, C.B., Jones, P.A. Epigenetic therapy of cancer: Past, present and future. Nat Rev Drug Discov 2006, 5(1): 37-50.
-
(2006)
Nat Rev Drug Discov
, vol.5
, Issue.1
, pp. 37-50
-
-
Yoo, C.B.1
Jones, P.A.2
-
26
-
-
33645086120
-
Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines
-
Stresemann, C., Brueckner, B., Musch, T., Stopper, H., Lyko, F. Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines. Cancer Res 2006, 66(5): 2794-800.
-
(2006)
Cancer Res
, vol.66
, Issue.5
, pp. 2794-2800
-
-
Stresemann, C.1
Brueckner, B.2
Musch, T.3
Stopper, H.4
Lyko, F.5
-
27
-
-
27744548525
-
Multiple markers for melanoma progression regulated by DNA methylation: Insights from transcriptomic studies
-
Gallagher, W.M., Bergin, O.E., Rafferty, M. et al. Multiple markers for melanoma progression regulated by DNA methylation: Insights from transcriptomic studies. Carcinogenesis 2005, 26(11): 1856-67.
-
(2005)
Carcinogenesis
, vol.26
, Issue.11
, pp. 1856-1867
-
-
Gallagher, W.M.1
Bergin, O.E.2
Rafferty, M.3
-
28
-
-
33745727112
-
HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors
-
Wang, S.E., Narasanna, A., Perez-Torres, M. et al. HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors. Cancer Cell 2006, 10(1): 25-38.
-
(2006)
Cancer Cell
, vol.10
, Issue.1
, pp. 25-38
-
-
Wang, S.E.1
Narasanna, A.2
Perez-Torres, M.3
-
29
-
-
34548692277
-
EGFR gene copy number alterations in primary cutaneous malignant melanomas are associated with poor prognosis
-
Rákosy, Z., Vízkeleti, L., Ecsedi, S. et al. EGFR gene copy number alterations in primary cutaneous malignant melanomas are associated with poor prognosis. Int J Cancer 2007, 121(8): 1729-37.
-
(2007)
Int J Cancer
, vol.121
, Issue.8
, pp. 1729-1737
-
-
Rákosy, Z.1
Vízkeleti, L.2
Ecsedi, S.3
-
30
-
-
14844354802
-
ErbB receptors mediate both migratory and proliferative activities in human melanocytes and melanoma cells
-
Gordon-Thomson, C., Jones, J., Mason, R.S., Moore, G.P. ErbB receptors mediate both migratory and proliferative activities in human melanocytes and melanoma cells. Melanoma Res 2005, 15(1): 21-8.
-
(2005)
Melanoma Res
, vol.15
, Issue.1
, pp. 21-28
-
-
Gordon-Thomson, C.1
Jones, J.2
Mason, R.S.3
Moore, G.P.4
-
31
-
-
26444574802
-
Development of farnesyl transferase inhibitors: A review
-
Appels, N.M., Beijnen, J.H., Schellens, J.H. Development of farnesyl transferase inhibitors: A review. Oncologist 2005, 10(8): 565-78.
-
(2005)
Oncologist
, vol.10
, Issue.8
, pp. 565-578
-
-
Appels, N.M.1
Beijnen, J.H.2
Schellens, J.H.3
-
32
-
-
33646261668
-
Targeting the mitogen-activated protein kinase pathway in the treatment of malignant melanoma
-
Panka, D.J., Atkins, M.B., Mier, J.W. Targeting the mitogen-activated protein kinase pathway in the treatment of malignant melanoma. Clin Cancer Res 2006, 12(7, Part 2): 2371s-5s.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.7 and PART 2
-
-
Panka, D.J.1
Atkins, M.B.2
Mier, J.W.3
-
33
-
-
18144364350
-
Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis
-
x
-
x Presta, M., Dell'Era, P., Mitola, S., Moroni, E., Ronca, R., Rusnati, M. Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis. Cytokine Growth Factor Rev 2005, 16(2): 159-78.
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, Issue.2
, pp. 159-178
-
-
Presta, M.1
Dell'Era, P.2
Mitola, S.3
Moroni, E.4
Ronca, R.5
Rusnati, M.6
-
34
-
-
28344434370
-
FGF1 inhibits p53-dependent apoptosis and cell cycle arrest via an intracrine pathway
-
Bouleau, S., Grimal, H., Rincheval, V., Godefroy, N., Mignotte, B., Vayssière, J.L., Renaud, F. FGF1 inhibits p53-dependent apoptosis and cell cycle arrest via an intracrine pathway. Oncogene 2005, 24(53): 7839-49.
-
(2005)
Oncogene
, vol.24
, Issue.53
, pp. 7839-7849
-
-
Bouleau, S.1
Grimal, H.2
Rincheval, V.3
Godefroy, N.4
Mignotte, B.5
Vayssière, J.L.6
Renaud, F.7
-
35
-
-
0029900931
-
Expression of FGF1 and FGFR1 in human melanoma tissues
-
Xerri, L., Battyani, Z., Grob, J.J., Parc, P., Hassoun, J., Bonerandi, J.J., Birnbaum, D. Expression of FGF1 and FGFR1 in human melanoma tissues. Melanoma Res 1996, 6(3): 223-30.
-
(1996)
Melanoma Res
, vol.6
, Issue.3
, pp. 223-230
-
-
Xerri, L.1
Battyani, Z.2
Grob, J.J.3
Parc, P.4
Hassoun, J.5
Bonerandi, J.J.6
Birnbaum, D.7
-
36
-
-
33645232700
-
Correlation of basic fibroblast growth factor expression with the invasion and the prognosis of oral squamous cell carcinoma
-
Hase, T., Kawashiri, S., Tanaka, A. et al. Correlation of basic fibroblast growth factor expression with the invasion and the prognosis of oral squamous cell carcinoma. J Oral Pathol Med 2006, 35(3): 136-9.
-
(2006)
J Oral Pathol Med
, vol.35
, Issue.3
, pp. 136-139
-
-
Hase, T.1
Kawashiri, S.2
Tanaka, A.3
-
37
-
-
0035861967
-
Signals via FGF receptor 2 regulate migration of endothelial cells
-
Nakamura, T., Mochizuki, Y., Kanetake, H., Kanda, S. Signals via FGF receptor 2 regulate migration of endothelial cells. Biochem Biophys Res Commun 2001, 289(4): 801-6.
-
(2001)
Biochem Biophys Res Commun
, vol.289
, Issue.4
, pp. 801-806
-
-
Nakamura, T.1
Mochizuki, Y.2
Kanetake, H.3
Kanda, S.4
-
38
-
-
0037301929
-
Angiogenesis in cutaneous melanoma: Pathogenesis and clinical implications
-
Srivastava, A., Ralhan, R., Kaur, J. Angiogenesis in cutaneous melanoma: Pathogenesis and clinical implications. Microsc Res Tech 2003, 60(2): 208-24.
-
(2003)
Microsc Res Tech
, vol.60
, Issue.2
, pp. 208-224
-
-
Srivastava, A.1
Ralhan, R.2
Kaur, J.3
-
39
-
-
24144454630
-
FLT3 tyrosine kinase inhibitors
-
Levis, M., Small, D. FLT3 tyrosine kinase inhibitors. Int J Hematol 2005, 82(2): 100-7.
-
(2005)
Int J Hematol
, vol.82
, Issue.2
, pp. 100-107
-
-
Levis, M.1
Small, D.2
-
40
-
-
0033111943
-
Expression and function of Flt3/flk2 in human tumor cell lines
-
Serve, H., Flesch, K., Serve, S., Fenski, R., Berdel, W.E. Expression and function of Flt3/flk2 in human tumor cell lines. Int J Oncol 1999, 14(4): 765-70.
-
(1999)
Int J Oncol
, vol.14
, Issue.4
, pp. 765-770
-
-
Serve, H.1
Flesch, K.2
Serve, S.3
Fenski, R.4
Berdel, W.E.5
-
41
-
-
35548970287
-
Heat shock proteins in cancer
-
Sherman, M., Multhoff, G. Heat shock proteins in cancer. Ann N Y Acad Sci 2007, 1113: 192-201.
-
(2007)
Ann N Y Acad Sci
, vol.1113
, pp. 192-201
-
-
Sherman, M.1
Multhoff, G.2
-
42
-
-
34548259088
-
Hsp70 chaperone as a survival factor in cell pathology
-
Guzhova, I., Margulis, B. Hsp70 chaperone as a survival factor in cell pathology. Int Rev Cytol 2006, 254: 101-49.
-
(2006)
Int Rev Cytol
, vol.254
, pp. 101-149
-
-
Guzhova, I.1
Margulis, B.2
-
43
-
-
12444278161
-
Heat shock protein 70 membrane expression and melanoma-associated marker phenotype in primary and metastatic melanoma
-
Farkas, B., Hantschel, M., Magyarlaki, M. et al. Heat shock protein 70 membrane expression and melanoma-associated marker phenotype in primary and metastatic melanoma. Melanoma Res 2003,13(2): 147-52.
-
(2003)
Melanoma Res
, vol.13
, Issue.2
, pp. 147-152
-
-
Farkas, B.1
Hantschel, M.2
Magyarlaki, M.3
-
44
-
-
34548189523
-
Extracellular heat shock protein 90: A role for a molecular chaperone in cell motility and cancer metastasis
-
Tsutsumi, S., Neckers, L. Extracellular heat shock protein 90: A role for a molecular chaperone in cell motility and cancer metastasis. Cancer Sci 2007, 98(10): 1536-9.
-
(2007)
Cancer Sci
, vol.98
, Issue.10
, pp. 1536-1539
-
-
Tsutsumi, S.1
Neckers, L.2
-
45
-
-
40149102363
-
HSP90 as a marker of progression in melanoma
-
McCarthy, M.M., Pick, E., Kluger, Y. et al. HSP90 as a marker of progression in melanoma. Ann Oncol 2008, 19(3): 590-4.
-
(2008)
Ann Oncol
, vol.19
, Issue.3
, pp. 590-594
-
-
McCarthy, M.M.1
Pick, E.2
Kluger, Y.3
-
46
-
-
20244381142
-
Emergence of nuclear heparanase induces differentiation of human mammary cancer cells
-
Nobuhisa, T., Naomoto, Y., Takaoka, M. et al. Emergence of nuclear heparanase induces differentiation of human mammary cancer cells. Biochem Biophys Res Commun 2005, 331(1): 175-80.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, Issue.1
, pp. 175-180
-
-
Nobuhisa, T.1
Naomoto, Y.2
Takaoka, M.3
-
47
-
-
40249098048
-
Heparanase and vascular endothelial growth factor expression in the progression of oral mucosal melanoma
-
Rivera, R.S., Nagatsuka, H., Siar, C.H. et al. Heparanase and vascular endothelial growth factor expression in the progression of oral mucosal melanoma. Oncol Rep 2008, 19(3): 657-61.
-
(2008)
Oncol Rep
, vol.19
, Issue.3
, pp. 657-661
-
-
Rivera, R.S.1
Nagatsuka, H.2
Siar, C.H.3
-
48
-
-
32544431582
-
Epigenetics and human disease: Translating basic biology into clinical applications
-
Rodenhiser, D., Mann, M. Epigenetics and human disease: Translating basic biology into clinical applications. CMAJ 2006, 174(3): 341-8.
-
(2006)
CMAJ
, vol.174
, Issue.3
, pp. 341-348
-
-
Rodenhiser, D.1
Mann, M.2
-
49
-
-
19544371601
-
Histone deacetylase inhibitors and malignant melanoma
-
Boyle, G.M., Marlyn, A.C., Parsons, P.G. Histone deacetylase inhibitors and malignant melanoma. Pigment Cell Res 2005, 18(3): 160-6.
-
(2005)
Pigment Cell Res
, vol.18
, Issue.3
, pp. 160-166
-
-
Boyle, G.M.1
Marlyn, A.C.2
Parsons, P.G.3
-
50
-
-
7544219925
-
Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer
-
Graaf, M.R., Richel, D.J., van Noorden, C.J., Guchelaar, H.J. Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer. Cancer Treat Rev 2004, 30(7): 609-41.
-
(2004)
Cancer Treat Rev
, vol.30
, Issue.7
, pp. 609-641
-
-
Graaf, M.R.1
Richel, D.J.2
van Noorden, C.J.3
Guchelaar, H.J.4
-
51
-
-
0034865456
-
Rho GTPases and cell migration
-
Ridley, A.J. Rho GTPases and cell migration. J Cell Sci 2001, 114(Pt. 15): 2713-22.
-
(2001)
J Cell Sci
, vol.114
, Issue.PART. 15
, pp. 2713-2722
-
-
Ridley, A.J.1
-
52
-
-
37149012084
-
Statins stimulate in vitro membrane FasL expression and lymphocyte apoptosis through RhoA/ROCK pathway in murine melanoma cells
-
Sarrabayrouse, G., Synaeve, C., Leveque, K., Favre, G., Tilkin-Mariamé, A.F. Statins stimulate in vitro membrane FasL expression and lymphocyte apoptosis through RhoA/ROCK pathway in murine melanoma cells. Neoplasia 2007, 9(12): 1078-90.
-
(2007)
Neoplasia
, vol.9
, Issue.12
, pp. 1078-1090
-
-
Sarrabayrouse, G.1
Synaeve, C.2
Leveque, K.3
Favre, G.4
Tilkin-Mariamé, A.F.5
-
53
-
-
25144496041
-
The IGF-1 receptor and its contributions to metastatic tumor growth-novel approaches to the inhibition of IGF-1R function
-
Bähr, C., Groner, B. The IGF-1 receptor and its contributions to metastatic tumor growth-novel approaches to the inhibition of IGF-1R function. Growth Factors 2005, 23(1): 1-14.
-
(2005)
Growth Factors
, vol.23
, Issue.1
, pp. 1-14
-
-
Bähr, C.1
Groner, B.2
-
54
-
-
21244493635
-
Treatment of hematologic malignancies and solid tumors by inhibiting IGF receptor signaling
-
Mitsiades, C.S., Mitsiades, N. Treatment of hematologic malignancies and solid tumors by inhibiting IGF receptor signaling. Expert Rev Anticancer Ther 2005, 5(3): 487-99.
-
(2005)
Expert Rev Anticancer Ther
, vol.5
, Issue.3
, pp. 487-499
-
-
Mitsiades, C.S.1
Mitsiades, N.2
-
55
-
-
0031772310
-
Expression of the insulin-like growth factor-1 receptor and its anti-apoptotic effect in malignant melanoma: A potential therapeutic target
-
Kanter-Lewensohn, L., Dricu, A., Wang, M., Wejde, J., Kiessling, R., Larsson, O. Expression of the insulin-like growth factor-1 receptor and its anti-apoptotic effect in malignant melanoma: A potential therapeutic target. Melanoma Res 1998, 8(5): 389-97.
-
(1998)
Melanoma Res
, vol.8
, Issue.5
, pp. 389-397
-
-
Kanter-Lewensohn, L.1
Dricu, A.2
Wang, M.3
Wejde, J.4
Kiessling, R.5
Larsson, O.6
-
56
-
-
0034222940
-
Expression of integrin alpha5beta1 and MMPs associated with epithelioid morphology and malignancy of uveal melanoma
-
Béliveau, A., Bérubé, M., Rousseau, A., Pelletier, G., Guérin, S.L. Expression of integrin alpha5beta1 and MMPs associated with epithelioid morphology and malignancy of uveal melanoma. Invest Ophthalmol Vis Sci 2000, 41(8): 2363-72.
-
(2000)
Invest Ophthalmol Vis Sci
, vol.41
, Issue.8
, pp. 2363-2372
-
-
Béliveau, A.1
Bérubé, M.2
Rousseau, A.3
Pelletier, G.4
Guérin, S.L.5
-
57
-
-
0037437153
-
Integrin-specific signaling pathways controlling focal adhesion formation and cell migration
-
Mostafavi-Pour, Z., Askari, J.A., Parkinson, S.J., Parker, P.J., Ng, T.T., Humphries, M.J. Integrin-specific signaling pathways controlling focal adhesion formation and cell migration. J Cell Biol 2003,161(1): 155-67.
-
(2003)
J Cell Biol
, vol.161
, Issue.1
, pp. 155-167
-
-
Mostafavi-Pour, Z.1
Askari, J.A.2
Parkinson, S.J.3
Parker, P.J.4
Ng, T.T.5
Humphries, M.J.6
-
58
-
-
0141780878
-
Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins
-
Bax, D.V., Bernard, S.E., Lomas, A. et al. Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins. J Biol Chem 2003, 278(36): 34605-16.
-
(2003)
J Biol Chem
, vol.278
, Issue.36
, pp. 34605-34616
-
-
Bax, D.V.1
Bernard, S.E.2
Lomas, A.3
-
59
-
-
19644367119
-
VEGF-integrin interplay controls tumor growth and vascularization
-
De, S., Razorenova, O., McCabe, N.P., O'Toole, T., Qin, J., Byzova, T.V. VEGF-integrin interplay controls tumor growth and vascularization. Proc Natl Acad Sci USA 2005, 102(21): 7589-94.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.21
, pp. 7589-7594
-
-
De, S.1
Razorenova, O.2
McCabe, N.P.3
O'Toole, T.4
Qin, J.5
Byzova, T.V.6
-
60
-
-
35349023688
-
Alpha-v-beta3 integrin expression in melanocytic nevi and cutaneous melanoma
-
Neto, D.S., Pantaleão, L., de Sá, B.C., Landman, G. Alpha-v-beta3 integrin expression in melanocytic nevi and cutaneous melanoma. J Cutan Pathol 2007, 34(11): 851-6.
-
(2007)
J Cutan Pathol
, vol.34
, Issue.11
, pp. 851-856
-
-
Neto, D.S.1
Pantaleão, L.2
de Sá, B.C.3
Landman, G.4
-
61
-
-
0036659130
-
Role of CXCL1 in tumorigenesis of melanoma
-
Dhawan, P., Richmond, A. Role of CXCL1 in tumorigenesis of melanoma. J Leukocyte Biol 2002, 72(1): 9-18.
-
(2002)
J Leukocyte Biol
, vol.72
, Issue.1
, pp. 9-18
-
-
Dhawan, P.1
Richmond, A.2
-
62
-
-
0036270898
-
The role of chemokines in melanoma tumor growth and metastasis
-
Payne, A.S., Cornelius, L.A. The role of chemokines in melanoma tumor growth and metastasis. J Invest Dermatol 2002,118(6): 915-22.
-
(2002)
J Invest Dermatol
, vol.118
, Issue.6
, pp. 915-922
-
-
Payne, A.S.1
Cornelius, L.A.2
-
63
-
-
0033913570
-
IL-8 expression in malignant melanoma: Implications in growth and metastasis
-
Singh, R.K., Varney, M.L. IL-8 expression in malignant melanoma: Implications in growth and metastasis. Histol Histopathol 2000, 15(3): 843-9.
-
(2000)
Histol Histopathol
, vol.15
, Issue.3
, pp. 843-849
-
-
Singh, R.K.1
Varney, M.L.2
-
64
-
-
33746072622
-
Imatinib inhibits c-Kit-induced hypoxia-inducible factor-1alpha activity and vascular endothelial growth factor expression in small cell lung cancer cells
-
Litz, J., Krystal, G.W. Imatinib inhibits c-Kit-induced hypoxia-inducible factor-1alpha activity and vascular endothelial growth factor expression in small cell lung cancer cells. Mol Cancer Ther 2006, 5(6): 1415-22.
-
(2006)
Mol Cancer Ther
, vol.5
, Issue.6
, pp. 1415-1422
-
-
Litz, J.1
Krystal, G.W.2
-
65
-
-
33746804126
-
The alpha subunit of the granulocyte-macrophage colony-stimulating factor receptor interacts with c-Kit and inhibits c-Kit signaling
-
Chen, J., Cárcamo, J.M., Golde, D.W. The alpha subunit of the granulocyte-macrophage colony-stimulating factor receptor interacts with c-Kit and inhibits c-Kit signaling. J Biol Chem 2006, 281(31): 22421-6.
-
(2006)
J Biol Chem
, vol.281
, Issue.31
, pp. 22421-22426
-
-
Chen, J.1
Cárcamo, J.M.2
Golde, D.W.3
-
66
-
-
33646272204
-
Chemotherapy and targeted therapy combinations in advanced melanoma
-
Flaherty, K.T. Chemotherapy and targeted therapy combinations in advanced melanoma. Clin Cancer Res 2006, 12(7, Part 2): 2366s-70s.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.7 and PART 2
-
-
Flaherty, K.T.1
-
67
-
-
33745307617
-
Ras, PI(3)K and mTOR signalling controls tumour cell growth
-
Shaw, R.J., Cantley, L.C. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature 2006, 441 (7092): 424-30.
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 424-430
-
-
Shaw, R.J.1
Cantley, L.C.2
-
68
-
-
31444434449
-
mTOR signalling: Implications for cancer and anticancer therapy
-
Petroulakis, E., Mamane, Y., Le Bacquer, O., Shahbazian, D., Sonenberg, N. mTOR signalling: Implications for cancer and anticancer therapy. Br J Cancer 2006, 94(2): 195-9.
-
(2006)
Br J Cancer
, vol.94
, Issue.2
, pp. 195-199
-
-
Petroulakis, E.1
Mamane, Y.2
Le Bacquer, O.3
Shahbazian, D.4
Sonenberg, N.5
-
69
-
-
40649126759
-
mTOR is activated in the majority of malignant melanomas
-
Karbowniczek, M., Spittle, C.S., Morrison, T., Wu, H., Henske, E.P. mTOR is activated in the majority of malignant melanomas. J Invest Dermatol 2008, 128(4): 980-7.
-
(2008)
J Invest Dermatol
, vol.128
, Issue.4
, pp. 980-987
-
-
Karbowniczek, M.1
Spittle, C.S.2
Morrison, T.3
Wu, H.4
Henske, E.P.5
-
70
-
-
15744380263
-
Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition
-
Ohren, J.F., Chen, H., Pavlovsky, A. et al. Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition. Nat Struct Mol Biol 2004, 11(12): 1192-7.
-
(2004)
Nat Struct Mol Biol
, vol.11
, Issue.12
, pp. 1192-1197
-
-
Ohren, J.F.1
Chen, H.2
Pavlovsky, A.3
-
71
-
-
33748063941
-
Roles of the RAF/ MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance
-
McCubrey, J.A., Steelman, L.S., Abrams, S.L. et al. Roles of the RAF/ MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance. Adv Enzyme Regul 2006, 46: 249-79.
-
(2006)
Adv Enzyme Regul
, vol.46
, pp. 249-279
-
-
McCubrey, J.A.1
Steelman, L.S.2
Abrams, S.L.3
-
72
-
-
15744393216
-
MEK1-dependent delayed expression of Fos-related antigen-1 counteracts c-Fos and p65 NF-kappaB-mediated interleukin-8 transcription in response to cytokines or growth factors
-
Hoffmann, E., Thiefes, A., Buhrow, D., Dittrich-Breiholz, O., Schneider, H., Resch, K., Kracht, M. MEK1-dependent delayed expression of Fos-related antigen-1 counteracts c-Fos and p65 NF-kappaB-mediated interleukin-8 transcription in response to cytokines or growth factors. J Biol Chem 2005, 280(10): 9706-18.
-
(2005)
J Biol Chem
, vol.280
, Issue.10
, pp. 9706-9718
-
-
Hoffmann, E.1
Thiefes, A.2
Buhrow, D.3
Dittrich-Breiholz, O.4
Schneider, H.5
Resch, K.6
Kracht, M.7
-
73
-
-
42149194973
-
Prognostic significance of cadherin-based adhesion molecules in cutaneous malignant melanoma
-
Kreizenbeck, G.M., Berger, A.J., Subtil, A., Rimm, D.L., Gould Rothberg, B.E. Prognostic significance of cadherin-based adhesion molecules in cutaneous malignant melanoma. Cancer Epidemiol Biomark Prev 2008, 17(4): 949-58.
-
(2008)
Cancer Epidemiol Biomark Prev
, vol.17
, Issue.4
, pp. 949-958
-
-
Kreizenbeck, G.M.1
Berger, A.J.2
Subtil, A.3
Rimm, D.L.4
Gould Rothberg, B.E.5
-
74
-
-
33644864094
-
Involvement of Src family kinases in N-cadherin phosphorylation and beta-catenin dissociation during transendothelial migration of melanoma cells
-
Qi, J., Wang, J., Romanyuk, O., Siu, C.H. Involvement of Src family kinases in N-cadherin phosphorylation and beta-catenin dissociation during transendothelial migration of melanoma cells. Mol Biol Cell 2006, 17(3): 1261-72.
-
(2006)
Mol Biol Cell
, vol.17
, Issue.3
, pp. 1261-1272
-
-
Qi, J.1
Wang, J.2
Romanyuk, O.3
Siu, C.H.4
-
75
-
-
5444267235
-
N-cadherin in the spotlight of cell-cell adhesion, differentiation, embryogenesis, invasion and signalling
-
Derycke, L.D., Bracke, M.E. N-cadherin in the spotlight of cell-cell adhesion, differentiation, embryogenesis, invasion and signalling. Int J Dev Biol 2004, 48(5-6): 463-76.
-
(2004)
Int J Dev Biol
, vol.48
, Issue.5-6
, pp. 463-476
-
-
Derycke, L.D.1
Bracke, M.E.2
-
76
-
-
33845414010
-
Cadherins in development: Cell adhesion, sorting, and tissue morphogenesis
-
Halbleib, J.M., Nelson, W.J. Cadherins in development: Cell adhesion, sorting, and tissue morphogenesis. Genes Dev 2006, 20(23): 3199-214.
-
(2006)
Genes Dev
, vol.20
, Issue.23
, pp. 3199-3214
-
-
Halbleib, J.M.1
Nelson, W.J.2
-
77
-
-
33947380240
-
Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology
-
Ratnam, K., Low, J.A. Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology. Clin Cancer Res 2007, 13(5): 1383-8.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.5
, pp. 1383-1388
-
-
Ratnam, K.1
Low, J.A.2
-
78
-
-
0035937826
-
A role for poly(ADP-ribose) polymerase in the transcriptional regulation of the melanoma growth stimulatory activity (CXCL1) gene expression
-
Nirodi, C., NagDas, S., Gygi, S.P., Olson, G., Aebersold, R., Richmond, A. A role for poly(ADP-ribose) polymerase in the transcriptional regulation of the melanoma growth stimulatory activity (CXCL1) gene expression. J Biol Chem 2001, 276(12): 9366-74.
-
(2001)
J Biol Chem
, vol.276
, Issue.12
, pp. 9366-9374
-
-
Nirodi, C.1
NagDas, S.2
Gygi, S.P.3
Olson, G.4
Aebersold, R.5
Richmond, A.6
-
79
-
-
18244376911
-
Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy
-
Muruganandham, M., Alfieri, A.A., Matei, C. et al. Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy. Clin Cancer Res 2005, 11(9): 3503-13.
-
(2005)
Clin Cancer Res
, vol.11
, Issue.9
, pp. 3503-3513
-
-
Muruganandham, M.1
Alfieri, A.A.2
Matei, C.3
-
80
-
-
33745817828
-
Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents
-
Khan, J,A., Tao, X., Tong, L. Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nat Struct Mol Biol 2006, 13(7): 582-8.
-
(2006)
Nat Struct Mol Biol
, vol.13
, Issue.7
, pp. 582-588
-
-
Khan, J.A.1
Tao, X.2
Tong, L.3
-
81
-
-
35848947564
-
Activation of FAK/PI3K/Rac1 signaling controls actin reorganization and inhibits cell motility in human cancer cells
-
Kallergi, G., Agelaki, S., Markomanolaki, H., Georgoulias, V., Stournaras, C. Activation of FAK/PI3K/Rac1 signaling controls actin reorganization and inhibits cell motility in human cancer cells. Cell Physiol Biochem 2007, 20(6): 977-86.
-
(2007)
Cell Physiol Biochem
, vol.20
, Issue.6
, pp. 977-986
-
-
Kallergi, G.1
Agelaki, S.2
Markomanolaki, H.3
Georgoulias, V.4
Stournaras, C.5
-
82
-
-
34248524006
-
Novel inhibitors in the treatment of metastatic melanoma
-
Kalinsky, K., Haluska, F.G. Novel inhibitors in the treatment of metastatic melanoma. Expert Rev Anticancer Ther 2007, 7(5): 715-24.
-
(2007)
Expert Rev Anticancer Ther
, vol.7
, Issue.5
, pp. 715-724
-
-
Kalinsky, K.1
Haluska, F.G.2
-
83
-
-
27944467785
-
New-clear functions of PDK1: Beyond a master kinase in the cytosol?
-
Kikani, C.K., Dong, L.Q., Liu, F. "New"-clear functions of PDK1: Beyond a master kinase in the cytosol? J Cell Biochem 2005, 96(6): 1157-62.
-
(2005)
J Cell Biochem
, vol.96
, Issue.6
, pp. 1157-1162
-
-
Kikani, C.K.1
Dong, L.Q.2
Liu, F.3
-
84
-
-
21244435590
-
Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1
-
Feldman, R.I., Wu, J.M., Polokoff, M.A. et al. Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1. J Biol Chem 2005, 280(20): 19867-74.
-
(2005)
J Biol Chem
, vol.280
, Issue.20
, pp. 19867-19874
-
-
Feldman, R.I.1
Wu, J.M.2
Polokoff, M.A.3
-
85
-
-
20444430119
-
-
Board, R., Jayson, G.C. Platelet-derived growth factor receptor (PDGFR): A target for anticancer therapeutics. Drug Resist Updat 2005, 8(1-2): 75-83.
-
Board, R., Jayson, G.C. Platelet-derived growth factor receptor (PDGFR): A target for anticancer therapeutics. Drug Resist Updat 2005, 8(1-2): 75-83.
-
-
-
-
86
-
-
36849088516
-
The RTK/RAS/ BRAF/PI3K pathways in melanoma: Biology, small molecule inhibitors, and potential applications
-
Haluska, F., Pemberton, T., Ibrahim, N., Kalinsky, K. The RTK/RAS/ BRAF/PI3K pathways in melanoma: Biology, small molecule inhibitors, and potential applications. Semin Oncol 2007, 34(6): 546-54.
-
(2007)
Semin Oncol
, vol.34
, Issue.6
, pp. 546-554
-
-
Haluska, F.1
Pemberton, T.2
Ibrahim, N.3
Kalinsky, K.4
-
87
-
-
16544382996
-
Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate
-
Furuhashi, M., Sjöblom, T., Abramsson, A. et al. Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate. Cancer Res 2004, 64(8): 2725-33.
-
(2004)
Cancer Res
, vol.64
, Issue.8
, pp. 2725-2733
-
-
Furuhashi, M.1
Sjöblom, T.2
Abramsson, A.3
-
88
-
-
21544442035
-
Protein kinase C in melanoma
-
Oka, M., Kikkawa, U. Protein kinase C in melanoma. Cancer Metastasis Rev 2005, 24(2): 287-300.
-
(2005)
Cancer Metastasis Rev
, vol.24
, Issue.2
, pp. 287-300
-
-
Oka, M.1
Kikkawa, U.2
-
89
-
-
0035999087
-
Protein kinase C isoforms in normal and transformed cells of the melanocytic lineage
-
Selzer, E., Okamoto, I., Lucas, T., Kodym, R., Pehamberger, H., Jansen, B. Protein kinase C isoforms in normal and transformed cells of the melanocytic lineage. Melanoma Res 2002, 12(3): 201-9.
-
(2002)
Melanoma Res
, vol.12
, Issue.3
, pp. 201-209
-
-
Selzer, E.1
Okamoto, I.2
Lucas, T.3
Kodym, R.4
Pehamberger, H.5
Jansen, B.6
-
90
-
-
31544442670
-
Oncogenic BRAF is required for tumor growth and maintenance in melanoma models
-
Hoeflich, K.P., Gray, D.C., Eby, M.T. et al. Oncogenic BRAF is required for tumor growth and maintenance in melanoma models. Cancer Res 2006, 66(2): 999-1006.
-
(2006)
Cancer Res
, vol.66
, Issue.2
, pp. 999-1006
-
-
Hoeflich, K.P.1
Gray, D.C.2
Eby, M.T.3
-
91
-
-
33745714241
-
-
Iervolino, A., Iuliano, R., Trapasso, F. et al. The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteins. Cancer Res 2006, 66(12): 6280-7.
-
Iervolino, A., Iuliano, R., Trapasso, F. et al. The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteins. Cancer Res 2006, 66(12): 6280-7.
-
-
-
-
92
-
-
0033637760
-
Mapping of melanoma modifier loci in RET transgenic mice
-
Dragani, T.A., Peissel, B., Zanesi, N. et al. Mapping of melanoma modifier loci in RET transgenic mice. Jpn J Cancer Res 2000, 91(11): 1142-7.
-
(2000)
Jpn J Cancer Res
, vol.91
, Issue.11
, pp. 1142-1147
-
-
Dragani, T.A.1
Peissel, B.2
Zanesi, N.3
-
93
-
-
33750083890
-
Src family kinases phosphorylate the Bcr-Abl SH3-SH2 region and modulate Bcr-Abl transforming activity
-
Meyn, M.A. 3rd., Wilson, M.B., Abdi, F.A. et al. Src family kinases phosphorylate the Bcr-Abl SH3-SH2 region and modulate Bcr-Abl transforming activity. J Biol Chem 2006, 281(41): 30907-16.
-
(2006)
J Biol Chem
, vol.281
, Issue.41
, pp. 30907-30916
-
-
Meyn 3rd, M.A.1
Wilson, M.B.2
Abdi, F.A.3
-
94
-
-
33846261886
-
The Src signaling pathway: A potential target in melanoma and other malignancies
-
Homsi, J., Cubitt, C., Daud, A. The Src signaling pathway: A potential target in melanoma and other malignancies. Expert Opin Ther Targets 2007, 11(1): 91-100.
-
(2007)
Expert Opin Ther Targets
, vol.11
, Issue.1
, pp. 91-100
-
-
Homsi, J.1
Cubitt, C.2
Daud, A.3
-
95
-
-
34247389227
-
Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma
-
Pashenkov, M., Goëss, G., Wagner, C. et al. Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma. J Clin Oncol 2006, 24(36): 5716-24.
-
(2006)
J Clin Oncol
, vol.24
, Issue.36
, pp. 5716-5724
-
-
Pashenkov, M.1
Goëss, G.2
Wagner, C.3
-
96
-
-
0141532262
-
Toll-like receptor signaling
-
Akira, S. Toll-like receptor signaling. J Biol Chem 2003, 278(40): 38105-8.
-
(2003)
J Biol Chem
, vol.278
, Issue.40
, pp. 38105-38108
-
-
Akira, S.1
-
97
-
-
29144455886
-
Rotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxation
-
Sari, L., Andricioaei, I. Rotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxation. Nucleic Acids Res 2005, 33(20): 6621-34.
-
(2005)
Nucleic Acids Res
, vol.33
, Issue.20
, pp. 6621-6634
-
-
Sari, L.1
Andricioaei, I.2
-
98
-
-
33749658088
-
Topoisomerase enzymes as therapeutic targets for cancer chemotherapy
-
Giles, G.I., Sharma, R.P. Topoisomerase enzymes as therapeutic targets for cancer chemotherapy. Med Chem 2005, 1(4): 383-94.
-
(2005)
Med Chem
, vol.1
, Issue.4
, pp. 383-394
-
-
Giles, G.I.1
Sharma, R.P.2
-
99
-
-
0031787528
-
Expression of DNA topoisomerase I, DNA topoisomerase II-alpha, and p53 in metastatic malignant melanoma
-
Lynch, B.J., Komaromy-Hiller, G., Bronstein, I.B., Holden, J.A. Expression of DNA topoisomerase I, DNA topoisomerase II-alpha, and p53 in metastatic malignant melanoma. Hum Pathol 1998, 29(11): 1240-5.
-
(1998)
Hum Pathol
, vol.29
, Issue.11
, pp. 1240-1245
-
-
Lynch, B.J.1
Komaromy-Hiller, G.2
Bronstein, I.B.3
Holden, J.A.4
-
100
-
-
28244433817
-
Human topoisomerase IIalpha rapidly relaxes positively supercoiled DNA: Implications for enzyme action ahead of replication forks
-
McClendon, A.K., Rodriguez, A.C., Osheroff, N. Human topoisomerase IIalpha rapidly relaxes positively supercoiled DNA: Implications for enzyme action ahead of replication forks. J Biol Chem 2005, 280(47): 39337-45.
-
(2005)
J Biol Chem
, vol.280
, Issue.47
, pp. 39337-39345
-
-
McClendon, A.K.1
Rodriguez, A.C.2
Osheroff, N.3
-
101
-
-
0034056352
-
Topoisomerase II-alpha expression in melanocytic nevi and malignant melanoma
-
Mu, X.C., Tran, T.A., Ross, J.S., Carlson, J.A. Topoisomerase II-alpha expression in melanocytic nevi and malignant melanoma. J Cutan Pathol 2000, 27(5): 242-8.
-
(2000)
J Cutan Pathol
, vol.27
, Issue.5
, pp. 242-248
-
-
Mu, X.C.1
Tran, T.A.2
Ross, J.S.3
Carlson, J.A.4
-
102
-
-
25444515482
-
Targeting TGFbeta signaling for cancer therapy
-
Iyer, S., Wang, Z.G., Akhtari, M., Zhao, W., Seth, P. Targeting TGFbeta signaling for cancer therapy. Cancer Biol Ther 2005, 4(3): 261-6.
-
(2005)
Cancer Biol Ther
, vol.4
, Issue.3
, pp. 261-266
-
-
Iyer, S.1
Wang, Z.G.2
Akhtari, M.3
Zhao, W.4
Seth, P.5
-
103
-
-
42249097586
-
Transforming growth factor-beta in cutaneous melanoma
-
Javelaud, D., Alexaki, V.I., Mauviel, A. Transforming growth factor-beta in cutaneous melanoma. Pigment Cell Melanoma Res 2008, 21(2): 123-32.
-
(2008)
Pigment Cell Melanoma Res
, vol.21
, Issue.2
, pp. 123-132
-
-
Javelaud, D.1
Alexaki, V.I.2
Mauviel, A.3
-
104
-
-
22844439645
-
Recent advances in the new generation taxane anticancer agents
-
Geney, R., Chen, J., Ojima, I. Recent advances in the new generation taxane anticancer agents. Med Chem 2005, 1(2): 125-39.
-
(2005)
Med Chem
, vol.1
, Issue.2
, pp. 125-139
-
-
Geney, R.1
Chen, J.2
Ojima, I.3
-
105
-
-
33645937652
-
Microtubule stabilizing agents: Their molecular signaling consequences and the potential for enhancement by drug combination
-
Bergstralh, D.T., Ting, J.P. Microtubule stabilizing agents: Their molecular signaling consequences and the potential for enhancement by drug combination. Cancer Treat Rev 2006, 32(3): 166-79.
-
(2006)
Cancer Treat Rev
, vol.32
, Issue.3
, pp. 166-179
-
-
Bergstralh, D.T.1
Ting, J.P.2
-
106
-
-
33644990998
-
Update on tubulin-binding agents
-
Attard, G., Greystoke, A., Kaye, S., De Bono, J. Update on tubulin-binding agents. Pathol Biol 2006, 54(2): 72-84.
-
(2006)
Pathol Biol
, vol.54
, Issue.2
, pp. 72-84
-
-
Attard, G.1
Greystoke, A.2
Kaye, S.3
De Bono, J.4
-
107
-
-
33645782015
-
TNF-alpha in cancer treatment: Molecular insights, antitumor effects, and clinical utility
-
van Horssen, R., Ten Hagen, T.L., Eggermont, A.M. TNF-alpha in cancer treatment: Molecular insights, antitumor effects, and clinical utility. Oncologist 2006, 11(4): 397-408.
-
(2006)
Oncologist
, vol.11
, Issue.4
, pp. 397-408
-
-
van Horssen, R.1
Ten Hagen, T.L.2
Eggermont, A.M.3
-
108
-
-
33744955317
-
Efficiency of recombinant human TNF in human cancer therapy
-
Lejeune, F.J., Liénard, D., Matter, M., Rüegg, C. Efficiency of recombinant human TNF in human cancer therapy. Cancer Immun 2006, 6: 6.
-
(2006)
Cancer Immun
, vol.6
, pp. 6
-
-
Lejeune, F.J.1
Liénard, D.2
Matter, M.3
Rüegg, C.4
-
109
-
-
23044500915
-
Pyruvate kinase type M2 and its role in tumor growth and spreading
-
Mazurek, S., Boschek, C.B., Hugo, F., Eigenbrodt, E. Pyruvate kinase type M2 and its role in tumor growth and spreading. Semin Cancer Biol 2005, 15(4): 300-8.
-
(2005)
Semin Cancer Biol
, vol.15
, Issue.4
, pp. 300-308
-
-
Mazurek, S.1
Boschek, C.B.2
Hugo, F.3
Eigenbrodt, E.4
-
110
-
-
27744532710
-
Tumor type M2 pyruvate kinase (TuM2-PK) as a novel plasma tumor marker in melanoma
-
Ugurel, S., Bell, N., Sucker, A., Zimpfer, A., Rittgen, W., Schadendorf, D. Tumor type M2 pyruvate kinase (TuM2-PK) as a novel plasma tumor marker in melanoma. Int J Cancer 2005, 117(5): 825-30.
-
(2005)
Int J Cancer
, vol.117
, Issue.5
, pp. 825-830
-
-
Ugurel, S.1
Bell, N.2
Sucker, A.3
Zimpfer, A.4
Rittgen, W.5
Schadendorf, D.6
-
111
-
-
0033572853
-
Protein specific N-glycosylation of tyrosinase and tyrosinase-related protein-1 in B16 mouse melanoma cells
-
Negroiu, G., Branza-Nichita, N., Petrescu, A.J., Dwek, R.A., Petrescu, S.M. Protein specific N-glycosylation of tyrosinase and tyrosinase-related protein-1 in B16 mouse melanoma cells. Biochem J 1999, 344(Pt. 3): 659-65.
-
(1999)
Biochem J
, vol.344
, Issue.PART. 3
, pp. 659-665
-
-
Negroiu, G.1
Branza-Nichita, N.2
Petrescu, A.J.3
Dwek, R.A.4
Petrescu, S.M.5
-
112
-
-
35948969144
-
Expression of melanin-related genes in cultured adult human retinal pigment epithelium and uveal melanoma cells
-
Lu, F., Yan, D., Zhou, X., Hu, D.N., Qu, J. Expression of melanin-related genes in cultured adult human retinal pigment epithelium and uveal melanoma cells. Mol Vis 2007, 13: 2066-72.
-
(2007)
Mol Vis
, vol.13
, pp. 2066-2072
-
-
Lu, F.1
Yan, D.2
Zhou, X.3
Hu, D.N.4
Qu, J.5
-
113
-
-
14644440555
-
Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
-
Hicklin, D.J., Ellis, L.M. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 2005, 23(5): 1011-27.
-
(2005)
J Clin Oncol
, vol.23
, Issue.5
, pp. 1011-1027
-
-
Hicklin, D.J.1
Ellis, L.M.2
-
114
-
-
33646107369
-
VEGF receptor signalling - In control of vascular function
-
Olsson, A.K., Dimberg, A., Kreuger, J., Claesson-Welsh, L. VEGF receptor signalling - In control of vascular function. Nat Rev Mol Cell Biol 2006, 7(5): 359-71.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, Issue.5
, pp. 359-371
-
-
Olsson, A.K.1
Dimberg, A.2
Kreuger, J.3
Claesson-Welsh, L.4
-
115
-
-
56749106582
-
VEGF, VEGFR1, and VEGFR2 expression in melanoma
-
Abst 8520
-
Mehnert, J.M., McCarthy, M.M., Aziz, S.A. et al. VEGF, VEGFR1, and VEGFR2 expression in melanoma. J Clin Oncol [43rd Annu Meet Am Soc Clin Oncol (ASCO) (June 1-5, Chicago) 2007] 2007, 25(18, Suppl.): Abst 8520.
-
J Clin Oncol [43rd Annu Meet Am Soc Clin Oncol (ASCO) (June 1-5, Chicago) 2007] 2007, 25(18, Suppl.)
-
-
Mehnert, J.M.1
McCarthy, M.M.2
Aziz, S.A.3
-
116
-
-
33344474964
-
Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis
-
Shibuya, M., Claesson-Welsh, L. Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis. Exp Cell Res 2006, 312(5): 549-60.
-
(2006)
Exp Cell Res
, vol.312
, Issue.5
, pp. 549-560
-
-
Shibuya, M.1
Claesson-Welsh, L.2
-
117
-
-
33747152506
-
Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration
-
Favier, B., Alam, A., Barron, P. et al. Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration. Blood 2006, 108(4): 1243-50.
-
(2006)
Blood
, vol.108
, Issue.4
, pp. 1243-1250
-
-
Favier, B.1
Alam, A.2
Barron, P.3
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