Down-regulation of the interferon signaling pathway in T lymphocytes from patients with metastatic melanoma

PLoS Medicine

Volumn 4, Issue 5, 2007, Pages 0897-0911

  Critchley Thorne, Rebecca J ^a   Yan, Ning ^a,b   Nacu, Serban ^b   Weber, Jeffrey ^c   Holmes, Susan P ^b   Lee, Peter P ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CD3 ANTIBODY; CD69 ANTIGEN; CD71 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; 3,4 BIS (2,4,5 TRIMETHYL THIOPHEN 3 YL)FURAN 2,5 DIONE; 3,4-BIS-(2,4,5-TRIMETHYL-THIOPHEN-3-YL)FURAN-2,5-DIONE; BIOLOGICAL MARKER; FURAN DERIVATIVE; IMMUNOLOGIC FACTOR; LEUKOCYTE ANTIGEN; STAT1 PROTEIN, HUMAN; THIOPHENE DERIVATIVE; TYROSINE;

ADULT; ARTICLE; B LYMPHOCYTE; CELL SORTER; CELL SURVIVAL; CONCENTRATION (PARAMETERS); CONFIDENCE INTERVAL; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IMMUNOPATHOLOGY; MALE; MELANOMA; METASTASIS; MOLECULAR MECHANICS; PERIPHERAL LYMPHOCYTE; POLYMERASE CHAIN REACTION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; STIMULATION; T LYMPHOCYTE; TH1 CELL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; DRUG EFFECT; GENETICS; IMMUNOLOGY; IMMUNOTHERAPY; IN VITRO STUDY; METABOLISM; NATURAL KILLER CELL; PATHOLOGY; PHOSPHORYLATION; SKIN TUMOR;

ANTIGENS, CD; BIOLOGICAL MARKERS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL SURVIVAL; DOWN-REGULATION; FURANS; HUMANS; IMMUNOLOGIC FACTORS; IMMUNOTHERAPY; INTERFERON-ALPHA; KILLER CELLS, NATURAL; MELANOMA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; STAT1 TRANSCRIPTION FACTOR; THIOPHENES; TYROSINE;

EID: 34249709048     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.0040176     Document Type: Article

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