-
1
-
-
0002960897
-
Endothelin-converting enzyme 2
-
in. Barrett, A. J., Rawlings, N. D. Woessner, J. F., eds. pp. Academic Press, San Diego, CA.
-
Ahn K. (1998) Endothelin-converting enzyme 2, in Handbook of Proteolytic Enzymes (Barrett A. J., Rawlings N. D. Woessner J. F., eds pp. 1090 1091. Academic Press, San Diego, CA.
-
(1998)
Handbook of Proteolytic Enzymes
, pp. 1090-1091
-
-
Ahn, K.1
-
2
-
-
1542404674
-
Peptidomics
-
Baggerman G., Verleyen P., Clynen E., Huybrechts J., De Loof A. Schoofs L. (2004) Peptidomics. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 803, 3 16.
-
(2004)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
, vol.803
, pp. 3-16
-
-
Baggerman, G.1
Verleyen, P.2
Clynen, E.3
Huybrechts, J.4
De Loof, A.5
Schoofs, L.6
-
3
-
-
0032530962
-
Existence of distinct tyrosylprotein sulfotransferase genes: Molecular characterization of tyrosylprotein sulfotransferase-2
-
Beisswanger R., Corbeil D., Vannier C., Thiele C., Dohrmann U., Kellner R., Ashman K., Niehrs C. Huttner W. B. (1998) Existence of distinct tyrosylprotein sulfotransferase genes: molecular characterization of tyrosylprotein sulfotransferase-2. Proc. Natl Acad. Sci. USA 95, 11134 11139.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 11134-11139
-
-
Beisswanger, R.1
Corbeil, D.2
Vannier, C.3
Thiele, C.4
Dohrmann, U.5
Kellner, R.6
Ashman, K.7
Niehrs, C.8
Huttner, W.B.9
-
4
-
-
0000478206
-
Glycosylation, phosphorylation, and sulfation of peptide hormones and their precursors
-
in. Fricker, L. D., ed. pp. CRC Press, Boca Raton, FL.
-
Bennett H. P. J. (1991) Glycosylation, phosphorylation, and sulfation of peptide hormones and their precursors, in Peptide Biosynthesis and Processing (Fricker L. D., ed pp. 111 140. CRC Press, Boca Raton, FL.
-
(1991)
Peptide Biosynthesis and Processing
, pp. 111-140
-
-
Bennett, H.P.J.1
-
5
-
-
0030839894
-
fat mice: A regional difference in the involvement of carboxypeptidase e (Cpe) in pro-CCK processing
-
fat mice: A regional difference in the involvement of carboxypeptidase E (Cpe) in pro-CCK processing. Endocrinology 138, 4034 4037.
-
(1997)
Endocrinology
, vol.138
, pp. 4034-4037
-
-
Cain, B.M.1
Wang, W.2
Beinfeld, M.C.3
-
6
-
-
9444264432
-
The carboxypeptidase e knockout mouse exhibits endocrinological and behavioral deficits
-
Cawley N. X., Zhou J., Hill J. M., Abebe D., Romboz S., Yanik T., Rodriguiz R. M., Wetsel W. C. Loh Y. P. (2004) The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits. Endocrinology 145, 5807 5819.
-
(2004)
Endocrinology
, vol.145
, pp. 5807-5819
-
-
Cawley, N.X.1
Zhou, J.2
Hill, J.M.3
Abebe, D.4
Romboz, S.5
Yanik, T.6
Rodriguiz, R.M.7
Wetsel, W.C.8
Loh, Y.P.9
-
7
-
-
0036645730
-
fat mice using differential isotopic tags and mass spectrometry
-
fat mice using differential isotopic tags and mass spectrometry. Anal. Chem. 74, 3190 3198.
-
(2002)
Anal. Chem.
, vol.74
, pp. 3190-3198
-
-
Che, F.-Y.1
Fricker, L.D.2
-
8
-
-
14744270672
-
Quantitative peptidomics of mouse pituitary: Comparison of different stable isotopic tags
-
Che F.-Y. Fricker L. D. (2005) Quantitative peptidomics of mouse pituitary: comparison of different stable isotopic tags. J. Mass Spectrom. 40, 238 249.
-
(2005)
J. Mass Spectrom.
, vol.40
, pp. 238-249
-
-
Che, F.-Y.1
Fricker, L.D.2
-
10
-
-
14744275484
-
fat/fat mouse pituitary using stable isotopic tags and mass spectrometry
-
fat/fat mouse pituitary using stable isotopic tags and mass spectrometry. J. Mass Spectrom. 40, 227 237.
-
(2005)
J. Mass Spectrom.
, vol.40
, pp. 227-237
-
-
Che, F.-Y.1
Biswas, R.2
Fricker, L.D.3
-
11
-
-
26844518104
-
Quantitative neuropeptidomics of microwave-irradiated mouse brain and pituitary
-
Che F.-Y., Lim J., Biswas R., Pan H. Fricker L. D. (2005b) Quantitative neuropeptidomics of microwave-irradiated mouse brain and pituitary. Mol. Cell Proteomics 4, 1391 1405.
-
(2005)
Mol. Cell Proteomics
, vol.4
, pp. 1391-1405
-
-
Che, F.-Y.1
Lim, J.2
Biswas, R.3
Pan, H.4
Fricker, L.D.5
-
12
-
-
14244256205
-
fat/fat mouse hypothalamus: Effect of food deprivation and exercise on peptide levels
-
fat/fat mouse hypothalamus: effect of food deprivation and exercise on peptide levels. J. Biol. Chem. 280, 4451 4461.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 4451-4461
-
-
Che, F.-Y.1
Yuan, Q.2
Kalinina, E.3
Fricker, L.D.4
-
13
-
-
38049037238
-
Optimization of neuropeptide extraction from the mouse hypothalamus
-
Che F. Y., Zhang X., Berezniuk I., Callaway M., Lim J. Fricker L. D. (2007) Optimization of neuropeptide extraction from the mouse hypothalamus. J. Proteome Res. 6, 4667 4676.
-
(2007)
J. Proteome Res.
, vol.6
, pp. 4667-4676
-
-
Che, F.Y.1
Zhang, X.2
Berezniuk, I.3
Callaway, M.4
Lim, J.5
Fricker, L.D.6
-
14
-
-
0034897806
-
A missense polymorphism in the human carboxypeptidase e gene alters its enzymatic activity: Possible implications in type 2 diabetes mellitus
-
Chen H., Jawahar S., Qian Y. et al. (2001) A missense polymorphism in the human carboxypeptidase E gene alters its enzymatic activity: possible implications in type 2 diabetes mellitus. Hum. Mut. 18, 120 131.
-
(2001)
Hum. Mut.
, vol.18
, pp. 120-131
-
-
Chen, H.1
Jawahar, S.2
Qian, Y.3
-
15
-
-
0031985151
-
Prodynorphin processing by proprotein convertase 2: Cleavage at single basic residues and enhanced processing in the presence of carboxypeptidase activity
-
Day R., Lazure C., Basak A., Boudreault A., Limperis P., Dong W. Lindberg I. (1998) Prodynorphin processing by proprotein convertase 2: cleavage at single basic residues and enhanced processing in the presence of carboxypeptidase activity. J. Biol. Chem. 273, 829 836.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 829-836
-
-
Day, R.1
Lazure, C.2
Basak, A.3
Boudreault, A.4
Limperis, P.5
Dong, W.6
Lindberg, I.7
-
16
-
-
0003149562
-
Peptide processing at monobasic sites
-
in. Fricker, L. D., ed. pp. CRC Press, Boca Raton, FL.
-
Devi L. (1991) Peptide processing at monobasic sites, in Peptide Biosynthesis and Processing (Fricker L. D., ed pp. 175 198. CRC Press, Boca Raton, FL.
-
(1991)
Peptide Biosynthesis and Processing
, pp. 175-198
-
-
Devi, L.1
-
17
-
-
33845388969
-
Rat neuropeptidomics by LC-MS/MS and MALDI-FTMS: Enhanced dissection and extraction techniques coupled with 2D RP-RP HPLC
-
Dowell J. A., Heyden W. V. Li L. (2006) Rat neuropeptidomics by LC-MS/MS and MALDI-FTMS: enhanced dissection and extraction techniques coupled with 2D RP-RP HPLC. J. Proteome Res. 5, 3368 3375.
-
(2006)
J. Proteome Res.
, vol.5
, pp. 3368-3375
-
-
Dowell, J.A.1
Heyden, W.V.2
Li, L.3
-
20
-
-
0029017876
-
Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon- sensitive metalloprotease with acidic pH optimum
-
Emoto N. Yanagisawa M. (1995) Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon-sensitive metalloprotease with acidic pH optimum. J. Biol. Chem. 270, 15262 15268.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 15262-15268
-
-
Emoto, N.1
Yanagisawa, M.2
-
21
-
-
0032478636
-
Gp180, a protein that binds duck hepatitis B virus particles, has metallocarboxypeptidase D-like enzymatic activity
-
Eng F. J., Novikova E. G., Kuroki K., Ganem D. Fricker L. D. (1998) gp180, a protein that binds duck hepatitis B virus particles, has metallocarboxypeptidase D-like enzymatic activity. J. Biol. Chem. 273, 8382 8388.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 8382-8388
-
-
Eng, F.J.1
Novikova, E.G.2
Kuroki, K.3
Ganem, D.4
Fricker, L.D.5
-
22
-
-
0032953879
-
Sequences within the cytoplasmic domain of gp180/carboxypeptidase D mediate localization to the trans-Golgi network
-
Eng F. J., Varlamov O. Fricker L. D. (1999) Sequences within the cytoplasmic domain of gp180/carboxypeptidase D mediate localization to the trans-Golgi network. Mol. Biol. Cell 10, 35 46.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 35-46
-
-
Eng, F.J.1
Varlamov, O.2
Fricker, L.D.3
-
23
-
-
34547116181
-
Neuropeptidomics strategies for specific and sensitive identification of endogenous peptides
-
Falth M., Skold K., Svensson M., Nilsson A., Fenyo D. Andren P. E. (2007) Neuropeptidomics strategies for specific and sensitive identification of endogenous peptides. Mol. Cell Proteomics 6, 1188 1197.
-
(2007)
Mol. Cell Proteomics
, vol.6
, pp. 1188-1197
-
-
Falth, M.1
Skold, K.2
Svensson, M.3
Nilsson, A.4
Fenyo, D.5
Andren, P.E.6
-
25
-
-
0023864209
-
Carboxypeptidase e
-
Fricker L. D. (1988) Carboxypeptidase E. Ann. Rev. Physiol. 50, 309 321.
-
(1988)
Ann. Rev. Physiol.
, vol.50
, pp. 309-321
-
-
Fricker, L.D.1
-
26
-
-
34548100559
-
Neuropeptidomics to study peptide processing in animal models of obesity
-
Fricker L. D. (2007) Neuropeptidomics to study peptide processing in animal models of obesity. Endocrinology 148, 4185 4190.
-
(2007)
Endocrinology
, vol.148
, pp. 4185-4190
-
-
Fricker, L.D.1
-
27
-
-
0033213907
-
Peptides, enzymes, and obesity: New insights from a "dead" enzyme
-
Fricker L. D. Leiter E. H. (1999) Peptides, enzymes, and obesity: new insights from a "dead" enzyme. Trends Biochem. Sci. 24, 390 393.
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 390-393
-
-
Fricker, L.D.1
Leiter, E.H.2
-
28
-
-
0001727492
-
Enkephalin convertase: Purification and characterization of a specific enkephalin-synthesizing carboxypeptidase localized to adrenal chromaffin granules
-
Fricker L. D. Snyder S. H. (1982) Enkephalin convertase: purification and characterization of a specific enkephalin-synthesizing carboxypeptidase localized to adrenal chromaffin granules. Proc. Natl Acad. Sci. USA 79, 3886 3890.
-
(1982)
Proc. Natl Acad. Sci. USA
, vol.79
, pp. 3886-3890
-
-
Fricker, L.D.1
Snyder, S.H.2
-
29
-
-
0029825451
-
Carboxypeptidase e activity is deficient in mice with the fat mutation: Effect on peptide processing
-
Fricker L. D., Berman Y. L., Leiter E. H. Devi L. A. (1996) Carboxypeptidase E activity is deficient in mice with the fat mutation: effect on peptide processing. J. Biol. Chem. 271, 30619 30624.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30619-30624
-
-
Fricker, L.D.1
Berman, Y.L.2
Leiter, E.H.3
Devi, L.A.4
-
30
-
-
0034651077
-
Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing
-
Fricker L. D., McKinzie A. A., Sun J. et al. (2000) Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing. J. Neurosci. 20, 639 648.
-
(2000)
J. Neurosci.
, vol.20
, pp. 639-648
-
-
Fricker, L.D.1
McKinzie, A.A.2
Sun, J.3
-
31
-
-
33644879722
-
Peptidomics: Identification and quantification of endogenous peptides in neuroendocrine tissues
-
Fricker L. D., Lim J., Pan H. Che F.-Y. (2006) Peptidomics: Identification and quantification of endogenous peptides in neuroendocrine tissues. Mass Spectrom. Rev. 25, 327 344.
-
(2006)
Mass Spectrom. Rev.
, vol.25
, pp. 327-344
-
-
Fricker, L.D.1
Lim, J.2
Pan, H.3
Che, F.-Y.4
-
32
-
-
12644253798
-
Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2
-
Furuta M., Yano H., Zhou A., Rouille Y., Holst J. J., Carroll R., Ravazzola M., Orci L., Furata H. Steiner D. F. (1997) Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2. Proc. Natl Acad. Sci. USA 94, 6646 6651.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 6646-6651
-
-
Furuta, M.1
Yano, H.2
Zhou, A.3
Rouille, Y.4
Holst, J.J.5
Carroll, R.6
Ravazzola, M.7
Orci, L.8
Furata, H.9
Steiner, D.F.10
-
33
-
-
0032488981
-
Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2
-
Furuta M., Carroll R., Martin S., Swift H. H., Ravazzola M., Orci L. Steiner D. F. (1998) Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2. J. Biol. Chem. 273, 3431 3437.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3431-3437
-
-
Furuta, M.1
Carroll, R.2
Martin, S.3
Swift, H.H.4
Ravazzola, M.5
Orci, L.6
Steiner, D.F.7
-
34
-
-
0035920170
-
Severe defect in proglucagon processing in islet A-cells of prohormone convertase 2 null mice
-
Furuta M., Zhou A., Webb G., Carroll R., Ravazzola M., Orci L. Steiner D. F. (2001) Severe defect in proglucagon processing in islet A-cells of prohormone convertase 2 null mice. J. Biol. Chem. 276, 27197 27202.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27197-27202
-
-
Furuta, M.1
Zhou, A.2
Webb, G.3
Carroll, R.4
Ravazzola, M.5
Orci, L.6
Steiner, D.F.7
-
35
-
-
0026742381
-
Regulation of carboxypeptidase E: Effect of pH, temperature, and Co++ on kinetic parameters of substrate hydrolysis
-
Greene D., Das B. Fricker L. D. (1992) Regulation of carboxypeptidase E: effect of pH, temperature, and Co++ on kinetic parameters of substrate hydrolysis. Biochem. J. 285, 613 618.
-
(1992)
Biochem. J.
, vol.285
, pp. 613-618
-
-
Greene, D.1
Das, B.2
Fricker, L.D.3
-
36
-
-
0036953551
-
Neuropeptides, food intake and body weight regulation: A hypothalamic focus
-
Hillebrand J. J., de Wied D. Adan R. A. (2002) Neuropeptides, food intake and body weight regulation: a hypothalamic focus. Peptides 23, 2283 2306.
-
(2002)
Peptides
, vol.23
, pp. 2283-2306
-
-
Hillebrand, J.J.1
De Wied, D.2
Adan, R.A.3
-
37
-
-
41149103075
-
Proteases for processing proneuropeptides into peptide neurotransmitters and hormones
-
Hook V., Funkelstein L., Lu D., Bark S., Wegrzyn J. Hwang S. R. (2008) Proteases for processing proneuropeptides into peptide neurotransmitters and hormones. Annu. Rev. Pharmacol. Toxicol. 48, 393 423.
-
(2008)
Annu. Rev. Pharmacol. Toxicol.
, vol.48
, pp. 393-423
-
-
Hook, V.1
Funkelstein, L.2
Lu, D.3
Bark, S.4
Wegrzyn, J.5
Hwang, S.R.6
-
38
-
-
33644843132
-
Discovering new invertebrate neuropeptides using mass spectrometry
-
Hummon A. B., Amare A. Sweedler J. V. (2006) Discovering new invertebrate neuropeptides using mass spectrometry. Mass Spectrom. Rev. 25, 77 98.
-
(2006)
Mass Spectrom. Rev.
, vol.25
, pp. 77-98
-
-
Hummon, A.B.1
Amare, A.2
Sweedler, J.V.3
-
39
-
-
34248177365
-
Cathepsin L expression is directed to secretory vesicles for enkephalin neuropeptide biosynthesis and secretion
-
Hwang S. R., Garza C., Mosier C., Toneff T., Wunderlich E., Goldsmith P. Hook V. (2007a) Cathepsin L expression is directed to secretory vesicles for enkephalin neuropeptide biosynthesis and secretion. J. Biol. Chem. 282, 9556 9563.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 9556-9563
-
-
Hwang, S.R.1
Garza, C.2
Mosier, C.3
Toneff, T.4
Wunderlich, E.5
Goldsmith, P.6
Hook, V.7
-
40
-
-
33846964171
-
Secretory vesicle aminopeptidase B related to neuropeptide processing: Molecular identification and subcellular localization to enkephalin- and NPY-containing chromaffin granules
-
Hwang S. R., O'Neill A., Bark S., Foulon T. Hook V. (2007b) Secretory vesicle aminopeptidase B related to neuropeptide processing: molecular identification and subcellular localization to enkephalin- and NPY-containing chromaffin granules. J. Neurochem. 100, 1340 1350.
-
(2007)
J. Neurochem.
, vol.100
, pp. 1340-1350
-
-
Hwang, S.R.1
O'Neill, A.2
Bark, S.3
Foulon, T.4
Hook, V.5
-
41
-
-
33645101466
-
fat/fat mice: Implications for neuropeptide discovery
-
fat/fat mice: implications for neuropeptide discovery. J. Neurochem. 96, 1169 1181.
-
(2006)
J. Neurochem.
, vol.96
, pp. 1169-1181
-
-
Lim, J.1
Berezniuk, I.2
Che, F.-Y.3
Parikh, R.4
Biswas, R.5
Pan, H.6
Fricker, L.D.7
-
42
-
-
0000791266
-
Peptide processing proteinases with selectivity for paired basic residues
-
in. Fricker, L. D., ed. pp. CRC Press, Boca Raton, FL.
-
Lindberg I. Hutton J. C. (1991) Peptide processing proteinases with selectivity for paired basic residues, in Peptide Biosynthesis and Processing (Fricker L. D., ed pp. 141 174. CRC Press, Boca Raton, FL.
-
(1991)
Peptide Biosynthesis and Processing
, pp. 141-174
-
-
Lindberg, I.1
Hutton, J.C.2
-
44
-
-
0025036862
-
Cellular and molecular aspects of peptide hormone biosynthesis
-
Mains R. E., Dickerson I. M., May V., Stoffers D. A., Perkins S. N., Ouafik L. H., Husten E. J. Eipper B. A. (1990) Cellular and molecular aspects of peptide hormone biosynthesis. Front Endocrinol. 11, 52 89.
-
(1990)
Front Endocrinol.
, vol.11
, pp. 52-89
-
-
Mains, R.E.1
Dickerson, I.M.2
May, V.3
Stoffers, D.A.4
Perkins, S.N.5
Ouafik, L.H.6
Husten, E.J.7
Eipper, B.A.8
-
45
-
-
0028237286
-
The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2
-
Martens G. J., Braks J. A., Eib D. W., Zhou Y. Lindberg I. (1994) The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2. Proc. Natl Acad. Sci. USA 91, 5784 5787.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 5784-5787
-
-
Martens, G.J.1
Braks, J.A.2
Eib, D.W.3
Zhou, Y.4
Lindberg, I.5
-
46
-
-
0035794161
-
ProSAAS processing in mouse brain and pituitary
-
Mzhavia N., Berman Y., Che F.-Y., Fricker L. D. Devi L. A. (2001) ProSAAS processing in mouse brain and pituitary. J. Biol. Chem. 276, 6207 6213.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 6207-6213
-
-
Mzhavia, N.1
Berman, Y.2
Che, F.-Y.3
Fricker, L.D.4
Devi, L.A.5
-
47
-
-
0036177067
-
Processing of proSAAS in neuroendocrine cell lines
-
Mzhavia N., Qian Y., Feng Y., Che F.-Y., Devi L. A. Fricker L. D. (2002) Processing of proSAAS in neuroendocrine cell lines. Biochem. J. 361, 67 76.
-
(2002)
Biochem. J.
, vol.361
, pp. 67-76
-
-
Mzhavia, N.1
Qian, Y.2
Feng, Y.3
Che, F.-Y.4
Devi, L.A.5
Fricker, L.D.6
-
48
-
-
0038013935
-
Characterization of endothelin-converting enzyme-2. Implication for a role in the nonclassical processing of regulatory peptides
-
Mzhavia N., Pan H., Che F.-Y., Fricker L. D. Devi L. A. (2003) Characterization of endothelin-converting enzyme-2. Implication for a role in the nonclassical processing of regulatory peptides. J. Biol. Chem. 278, 14704 14711.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 14704-14711
-
-
Mzhavia, N.1
Pan, H.2
Che, F.-Y.3
Fricker, L.D.4
Devi, L.A.5
-
49
-
-
0029040210
-
Hyperproinsulinemia in obese fat/fat mice associated with a point mutation in the carboxypeptidase e gene and reduced carboxypeptidase e activity in the pancreatic islets
-
Naggert J. K., Fricker L. D., Varlamov O., Nishina P. M., Rouille Y., Steiner D. F., Carroll R. J., Paigen B. J. Leiter E. H. (1995) Hyperproinsulinemia in obese fat/fat mice associated with a point mutation in the carboxypeptidase E gene and reduced carboxypeptidase E activity in the pancreatic islets. Nat. Genet. 10, 135 142.
-
(1995)
Nat. Genet.
, vol.10
, pp. 135-142
-
-
Naggert, J.K.1
Fricker, L.D.2
Varlamov, O.3
Nishina, P.M.4
Rouille, Y.5
Steiner, D.F.6
Carroll, R.J.7
Paigen, B.J.8
Leiter, E.H.9
-
50
-
-
0030725756
-
Furin: A mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins
-
Nakayama K. (1997) Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins. Biochem. J. 327, 625 635.
-
(1997)
Biochem. J.
, vol.327
, pp. 625-635
-
-
Nakayama, K.1
-
51
-
-
0031603460
-
Prediction of signal peptides and signal anchors by a hidden Markov model
-
Nielsen H. Krogh A. (1998) Prediction of signal peptides and signal anchors by a hidden Markov model. Proc. Int. Conf. Intell. Syst. Mol. Biol. 6, 122 130.
-
(1998)
Proc. Int. Conf. Intell. Syst. Mol. Biol.
, vol.6
, pp. 122-130
-
-
Nielsen, H.1
Krogh, A.2
-
52
-
-
0030614959
-
Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
-
Nielsen H., Engelbrecht J., Brunak S. von Heijne G. (1997) Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 10, 1 6.
-
(1997)
Protein Eng.
, vol.10
, pp. 1-6
-
-
Nielsen, H.1
Engelbrecht, J.2
Brunak, S.3
Von Heijne, G.4
-
53
-
-
0029670114
-
A novel [125I]iodinated carboxypeptidase a substrate detects a metallopeptidase activity distinct from carboxypeptidase a in brain
-
Normant E., Schwartz J. C. Gros C. (1996) A novel [125I]iodinated carboxypeptidase A substrate detects a metallopeptidase activity distinct from carboxypeptidase A in brain. Neuropeptides 30, 13 17.
-
(1996)
Neuropeptides
, vol.30
, pp. 13-17
-
-
Normant, E.1
Schwartz, J.C.2
Gros, C.3
-
54
-
-
0032878243
-
Characterization of the enzymatic properties of the first and second domains of metallocarboxypeptidase D
-
Novikova E. G., Eng F. J., Yan L., Qian Y. Fricker L. D. (1999) Characterization of the enzymatic properties of the first and second domains of metallocarboxypeptidase D. J. Biol. Chem. 274, 28887 28892.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28887-28892
-
-
Novikova, E.G.1
Eng, F.J.2
Yan, L.3
Qian, Y.4
Fricker, L.D.5
-
55
-
-
0034681380
-
Carboxypeptidase Z is present in the regulated secretory pathway and extracellular matrix in cultured cells and in human tissues
-
Novikova E. G., Reznik S. E., Varlamov O. Fricker L. D. (2000) Carboxypeptidase Z is present in the regulated secretory pathway and extracellular matrix in cultured cells and in human tissues. J. Biol. Chem. 275, 4865 4870.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 4865-4870
-
-
Novikova, E.G.1
Reznik, S.E.2
Varlamov, O.3
Fricker, L.D.4
-
56
-
-
33748051433
-
The role of prohormone convertase-2 in hypothalamic neuropeptide processing: A quantitative neuropeptidomic study
-
Pan H., Che F. Y., Peng B., Steiner D. F., Pintar J. E. Fricker L. D. (2006) The role of prohormone convertase-2 in hypothalamic neuropeptide processing: a quantitative neuropeptidomic study. J. Neurochem. 98, 1763 1777.
-
(2006)
J. Neurochem.
, vol.98
, pp. 1763-1777
-
-
Pan, H.1
Che, F.Y.2
Peng, B.3
Steiner, D.F.4
Pintar, J.E.5
Fricker, L.D.6
-
58
-
-
0025840609
-
Primary structure and functional expression of a glutaminyl cyclase
-
Pohl T., Zimmer M., Mugele K. Spiess J. (1991) Primary structure and functional expression of a glutaminyl cyclase. Proc. Natl Acad. Sci. USA 88, 10059 10063.
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 10059-10063
-
-
Pohl, T.1
Zimmer, M.2
Mugele, K.3
Spiess, J.4
-
59
-
-
0000821179
-
New insights into copper monooxygenases and peptide amidation: Structure, mechanism and function
-
Prigge S. T., Mains R. E., Eipper B. A. Amzel L. M. (2000) New insights into copper monooxygenases and peptide amidation: structure, mechanism and function. Cell. Mol. Life Sci. 57, 1236 1259.
-
(2000)
Cell. Mol. Life Sci.
, vol.57
, pp. 1236-1259
-
-
Prigge, S.T.1
Mains, R.E.2
Eipper, B.A.3
Amzel, L.M.4
-
60
-
-
0029943687
-
Impaired processing of brain proneurotensin and promelanin-concentrating hormone in obese fat/fat mice
-
Rovere C., Viale A., Nahon J. Kitabgi P. (1996) Impaired processing of brain proneurotensin and promelanin-concentrating hormone in obese fat/fat mice. Endocrinology 137, 2954 2958.
-
(1996)
Endocrinology
, vol.137
, pp. 2954-2958
-
-
Rovere, C.1
Viale, A.2
Nahon, J.3
Kitabgi, P.4
-
61
-
-
0035109058
-
Tissue distribution and processing of proSAAS by proprotein convertases
-
Sayah M., Fortenberry Y., Cameron A. Lindberg I. (2001) Tissue distribution and processing of proSAAS by proprotein convertases. J. Neurochem. 76, 1833 1841.
-
(2001)
J. Neurochem.
, vol.76
, pp. 1833-1841
-
-
Sayah, M.1
Fortenberry, Y.2
Cameron, A.3
Lindberg, I.4
-
62
-
-
33750109567
-
Proprotein convertases: Lessons from knockouts
-
Scamuffa N., Calvo F., Chretien M., Seidah N. G. Khatib A. M. (2006) Proprotein convertases: lessons from knockouts. FASEB J. 20, 1954 1963.
-
(2006)
FASEB J.
, vol.20
, pp. 1954-1963
-
-
Scamuffa, N.1
Calvo, F.2
Chretien, M.3
Seidah, N.G.4
Khatib, A.M.5
-
63
-
-
0343307146
-
Eukaryotic protein processing: Endoproteolysis of precursor proteins
-
Seidah N. G. Chretien M. (1997) Eukaryotic protein processing: endoproteolysis of precursor proteins. Curr. Opin. Biotechnol. 8, 602 607.
-
(1997)
Curr. Opin. Biotechnol.
, vol.8
, pp. 602-607
-
-
Seidah, N.G.1
Chretien, M.2
-
64
-
-
14244267611
-
Proprotein convertase 2
-
in. Barrett, A. J., Rawlings, N. D. Woessner, J. F., eds. pp. Academic Press, San Diego, CA.
-
Seidah N. G. Chretien M. (2004a) Proprotein convertase 2, in Handbook of Proteolytic Enzymes (Barrett A. J., Rawlings N. D. Woessner J. F., eds pp. 1865 1868. Academic Press, San Diego, CA.
-
(2004)
Handbook of Proteolytic Enzymes
, pp. 1865-1868
-
-
Seidah, N.G.1
Chretien, M.2
-
65
-
-
14244256220
-
Proprotein convertase I
-
in. Barrett, A. J., Rawlings, N. D. Woessner, J. F., eds. pp. Academic Press, San Diego, CA.
-
Seidah N. G. Chretien M. (2004b) Proprotein convertase I, in Handbook of Proteolytic Enzymes (Barrett A. J., Rawlings N. D. Woessner J. F., eds pp. 1861 1864. Academic Press, San Diego, CA.
-
(2004)
Handbook of Proteolytic Enzymes
, pp. 1861-1864
-
-
Seidah, N.G.1
Chretien, M.2
-
66
-
-
0036224579
-
A neuroproteomic approach to targeting neuropeptides in the brain
-
Skold K., Svensson M., Kaplan A., Bjorkesten L., Astrom J. Andren P. E. (2002) A neuroproteomic approach to targeting neuropeptides in the brain. Proteomics 2, 447 454.
-
(2002)
Proteomics
, vol.2
, pp. 447-454
-
-
Skold, K.1
Svensson, M.2
Kaplan, A.3
Bjorkesten, L.4
Astrom, J.5
Andren, P.E.6
-
67
-
-
12144286825
-
Deficits in reproduction and pro-gonadotropin-releasing hormone processing in male Cpefat mice
-
Srinivasan S., Bunch D. O., Feng Y. et al. (2004) Deficits in reproduction and pro-gonadotropin-releasing hormone processing in male Cpefat mice. Endocrinology 145, 2023 2034.
-
(2004)
Endocrinology
, vol.145
, pp. 2023-2034
-
-
Srinivasan, S.1
Bunch, D.O.2
Feng, Y.3
-
68
-
-
0141620180
-
Neuropeptides: General characteristics and neuropharmaceutical potential in treating CNS disorders
-
Strand F. L. (2003) Neuropeptides: general characteristics and neuropharmaceutical potential in treating CNS disorders. Prog. Drug Res. 61, 1 37.
-
(2003)
Prog. Drug Res.
, vol.61
, pp. 1-37
-
-
Strand, F.L.1
-
70
-
-
33846262180
-
Neuropeptidomics: MS applied to the discovery of novel peptides from the brain
-
Svensson M., Skold K., Nilsson A., Falth M., Nydahl K., Svenningsson P. Andren P. E. (2007a) Neuropeptidomics: MS applied to the discovery of novel peptides from the brain. Anal. Chem. 79, 15 21.
-
(2007)
Anal. Chem.
, vol.79
, pp. 15-21
-
-
Svensson, M.1
Skold, K.2
Nilsson, A.3
Falth, M.4
Nydahl, K.5
Svenningsson, P.6
Andren, P.E.7
-
71
-
-
34250841238
-
Neuropeptidomics: Expanding proteomics downwards
-
Svensson M., Skold K., Nilsson A., Falth M., Svenningsson P. Andren P. E. (2007b) Neuropeptidomics: expanding proteomics downwards. Biochem. Soc. Trans. 35, 588 593.
-
(2007)
Biochem. Soc. Trans.
, vol.35
, pp. 588-593
-
-
Svensson, M.1
Skold, K.2
Nilsson, A.3
Falth, M.4
Svenningsson, P.5
Andren, P.E.6
-
72
-
-
0036253032
-
ACEH/ACE2 is a novel mammalian metallocarboxypeptidase and a homologue of angiotensin-converting enzyme insensitive to ACE inhibitors
-
Turner A. J., Tipnis S. R., Guy J. L., Rice G. Hooper N. M. (2002) ACEH/ACE2 is a novel mammalian metallocarboxypeptidase and a homologue of angiotensin-converting enzyme insensitive to ACE inhibitors. Can. J. Physiol. Pharmacol. 80, 346 353.
-
(2002)
Can. J. Physiol. Pharmacol.
, vol.80
, pp. 346-353
-
-
Turner, A.J.1
Tipnis, S.R.2
Guy, J.L.3
Rice, G.4
Hooper, N.M.5
-
73
-
-
0030888254
-
Effect of carboxypeptidase e deficiency on progastrin processing and gastrin mRNA expression in mice with the fat mutation
-
Udupi V., Gomez P., Song L., Varlamov O., Reed J. T., Leiter E. H., Fricker L. D. Greeley G. H. J. (1997) Effect of carboxypeptidase E deficiency on progastrin processing and gastrin mRNA expression in mice with the fat mutation. Endocrinology 138, 1959 1963.
-
(1997)
Endocrinology
, vol.138
, pp. 1959-1963
-
-
Udupi, V.1
Gomez, P.2
Song, L.3
Varlamov, O.4
Reed, J.T.5
Leiter, E.H.6
Fricker, L.D.7
Greeley, G.H.J.8
-
74
-
-
0029995282
-
The C-terminal region of carboxypeptidase e involved in membrane binding is distinct from the region involved with intracellular routing
-
Varlamov O. Fricker L. D. (1996) The C-terminal region of carboxypeptidase E involved in membrane binding is distinct from the region involved with intracellular routing. J. Biol. Chem. 271, 6077 6083.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6077-6083
-
-
Varlamov, O.1
Fricker, L.D.2
-
75
-
-
0031956333
-
Intracellular trafficking of metallocarboxypeptidase D in AtT-20 cells: Localization to the trans-Golgi network and recycling from the cell surface
-
Varlamov O. Fricker L. D. (1998) Intracellular trafficking of metallocarboxypeptidase D in AtT-20 cells: localization to the trans-Golgi network and recycling from the cell surface. J. Cell Sci. 111, 877 885.
-
(1998)
J. Cell Sci.
, vol.111
, pp. 877-885
-
-
Varlamov, O.1
Fricker, L.D.2
-
76
-
-
0029953281
-
Induced and spontaneous mutations at Ser202 of carboxypeptidase E: Effect on enzyme expression, activity, and intracellular routing
-
Varlamov O., Leiter E. H. Fricker L. D. (1996) Induced and spontaneous mutations at Ser202 of carboxypeptidase E: effect on enzyme expression, activity, and intracellular routing. J. Biol. Chem. 271, 13981 13986.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13981-13986
-
-
Varlamov, O.1
Leiter, E.H.2
Fricker, L.D.3
-
77
-
-
0033591343
-
Localization of metallocarboxypeptidase D in AtT-20 cells: Potential role in prohormone processing
-
Varlamov O., Eng F. J., Novikova E. G. Fricker L. D. (1999a) Localization of metallocarboxypeptidase D in AtT-20 cells: potential role in prohormone processing. J. Biol. Chem. 274, 14759 14767.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14759-14767
-
-
Varlamov, O.1
Eng, F.J.2
Novikova, E.G.3
Fricker, L.D.4
-
78
-
-
0033553401
-
Biosynthesis and packaging of carboxypeptidase D into nascent secretory vesicles in pituitary cell lines
-
Varlamov O., Wu F., Shields D. Fricker L. D. (1999b) Biosynthesis and packaging of carboxypeptidase D into nascent secretory vesicles in pituitary cell lines. J. Biol. Chem. 274, 14040 14045.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14040-14045
-
-
Varlamov, O.1
Wu, F.2
Shields, D.3
Fricker, L.D.4
-
79
-
-
34249295158
-
Proteomics of neuroendocrine secretory vesicles reveal distinct functional systems for biosynthesis and exocytosis of peptide hormones and neurotransmitters
-
Wegrzyn J., Lee J., Neveu J. M., Lane W. S. Hook V. (2007) Proteomics of neuroendocrine secretory vesicles reveal distinct functional systems for biosynthesis and exocytosis of peptide hormones and neurotransmitters. J. Proteome Res. 6, 1652 1665.
-
(2007)
J. Proteome Res.
, vol.6
, pp. 1652-1665
-
-
Wegrzyn, J.1
Lee, J.2
Neveu, J.M.3
Lane, W.S.4
Hook, V.5
-
80
-
-
0037177891
-
Identification and characterization of three members of the human metallocarboxypeptidase gene family
-
Wei S., Segura S., Vendrell J., Aviles F. X., Lanoue E., Day R., Feng Y. Fricker L. D. (2002) Identification and characterization of three members of the human metallocarboxypeptidase gene family. J. Biol. Chem. 277, 14954 14964.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 14954-14964
-
-
Wei, S.1
Segura, S.2
Vendrell, J.3
Aviles, F.X.4
Lanoue, E.5
Day, R.6
Feng, Y.7
Fricker, L.D.8
-
82
-
-
11144355761
-
Obesity and diabetes in transgenic mice expressing proSAAS
-
Wei S., Feng Y., Che F.-Y., Pan H., Mzhavia N., Devi L., McKenzie A. A., Levin N., Richards W. G. Fricker L. D. (2004) Obesity and diabetes in transgenic mice expressing proSAAS. J. Endocrinol. 180, 357 368.
-
(2004)
J. Endocrinol.
, vol.180
, pp. 357-368
-
-
Wei, S.1
Feng, Y.2
Che, F.-Y.3
Pan, H.4
Mzhavia, N.5
Devi, L.6
McKenzie, A.A.7
Levin, N.8
Richards, W.G.9
Fricker, L.D.10
-
83
-
-
0033821404
-
The hypothalamus and the regulation of energy homeostasis: Lifting the lid on a black box
-
Williams G., Harrold J. A. Cutler D. J. (2000) The hypothalamus and the regulation of energy homeostasis: lifting the lid on a black box. Proc. Nutr. Soc. 59, 385 396.
-
(2000)
Proc. Nutr. Soc.
, vol.59
, pp. 385-396
-
-
Williams, G.1
Harrold, J.A.2
Cutler, D.J.3
-
85
-
-
0033597852
-
Proteolytic processing in the secretory pathway
-
Zhou A., Webb G., Zhu X. Steiner D. F. (1999) Proteolytic processing in the secretory pathway. J. Biol. Chem. 274, 20745 20748.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20745-20748
-
-
Zhou, A.1
Webb, G.2
Zhu, X.3
Steiner, D.F.4
-
86
-
-
0029075455
-
7B2 facilitates the maturation of proPC2 in neuroendocrine cells and is required for the expression of enzymatic activity
-
Zhu X. Lindberg I. (1995) 7B2 facilitates the maturation of proPC2 in neuroendocrine cells and is required for the expression of enzymatic activity. J. Cell Biol. 129, 1641 1650.
-
(1995)
J. Cell Biol.
, vol.129
, pp. 1641-1650
-
-
Zhu, X.1
Lindberg, I.2
-
87
-
-
0029954032
-
Internal cleavage of the inhibitory 7B2 CT peptide by PC2: A potential mechanism for its inactivation
-
Zhu X., Rouille Y., Lamango N. S., Steiner D. F. Lindberg I. (1996) Internal cleavage of the inhibitory 7B2 CT peptide by PC2: a potential mechanism for its inactivation. Proc. Natl Acad. Sci. USA 93, 4919 4924.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 4919-4924
-
-
Zhu, X.1
Rouille, Y.2
Lamango, N.S.3
Steiner, D.F.4
Lindberg, I.5
|