Severe Defect in Proglucagon Processing in Islet A-cells of Prohormone Convertase 2 Null Mice

Journal of Biological Chemistry

Volumn 276, Issue 29, 2001, Pages 27197-27202

  Furuta, Machi ^a,c   Zhou, An ^d   Webb, Gene ^a   Carroll, Raymond ^a   Ravazzola, Mariella ^b   Orci, Lelio ^b   Steiner, Donald F ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^c WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^d LEGACY RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; BLOOD; CELLS; ENZYMES; GLUCOSE; INSULIN;

GLUCAGON; HYPOGLYCEMIA;

HORMONES;

FURIN; GLUCAGON; GLUCOSE; INSULIN; PROGLUCAGON; PROPROTEIN CONVERTASE 2; UNCLASSIFIED DRUG; MESSENGER RNA; PROTEIN PRECURSOR; SUBTILISIN;

ANIMAL CELL; ARTICLE; CELL ULTRASTRUCTURE; GENE DELETION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HOMOZYGOSITY; HYPERPLASIA; HYPERTROPHY; HYPOGLYCEMIA; IMMUNOCYTOCHEMISTRY; MOUSE; NONHUMAN; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; SECRETORY GRANULE; ANIMAL; CYTOLOGY; ENZYMOLOGY; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; MOUSE MUTANT; PANCREAS ISLET; WESTERN BLOTTING;

ANIMALIA; RODENTIA;

ANIMALS; BLOTTING, WESTERN; GLUCAGON; IMMUNOHISTOCHEMISTRY; ISLETS OF LANGERHANS; MICE; MICE, MUTANT STRAINS; PROGLUCAGON; PROPROTEIN CONVERTASE 2; PROTEIN PRECURSORS; RNA, MESSENGER; SUBTILISINS;

EID: 0035920170     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103362200     Document Type: Article

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