Short communication differential modulation of the uptake currents by redox interconversion of cysteine residues in the human neuronal glutamate transporter EAAC1

European Journal of Neuroscience

Volumn 9, Issue 10, 1997, Pages 2207-2212

  Trotti, Davide ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Endogenous oxidant; Glutamate transporter; Human eaac1; Peroxynitrite; Redox

Indexed keywords

5,5' DITHIOBIS(2 NITROBENZOIC ACID); CARRIER PROTEIN; CHLORIDE ION; CYSTEINE; DISULFIDE; DITHIOTHREITOL; EXCITOTOXIN; GLUTAMIC ACID; PEROXYNITRITE;

AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; CENTRAL NERVOUS SYSTEM; CHLORIDE CONDUCTANCE; CONTROLLED STUDY; ISOTOPE LABELING; NEUROTRANSMISSION; NONHUMAN; OOCYTE; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS;

AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; CARRIER PROTEINS; CYSTEINE; DITHIONITROBENZOIC ACID; DITHIOTHREITOL; EVOKED POTENTIALS; EXCITATORY AMINO ACID TRANSPORTER 3; FEMALE; GLUTAMATE PLASMA MEMBRANE TRANSPORT PROTEINS; GLUTAMATES; HUMANS; NEURONS; NITRATES; OOCYTES; OXIDANTS; OXIDATION-REDUCTION; PATCH-CLAMP TECHNIQUES; SYMPORTERS; XENOPUS;

EID: 0030690557     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1997.tb01388.x     Document Type: Article

References (3)

1. Attwell, D., Barbour, B. and Szatkowski, M. (1993) Nonvesicular release of neurotransmitter. Neuron, 11, 401-407.
2. Barbour, B., Szatkowski, M., Ingledew, N. and Attwell, D. (1989) Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells. Nature, 342, 918-920.
3. Billups, B., Rossi, D. and Attwell, D. (1996) Anion conductance behavior of the glutamate uptake carrier in salamander retinal glial cells. J. Neurosci., 16, 6722-6731.