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Volumn 18, Issue 7, 1998, Pages 2475-2485

Multiple signaling pathways regulate cell surface expression and activity of the excitatory amino acid carrier 1 subtype of Glu transporter in C6 glioma

Author keywords

C6 glioma; EAAC1; Excitatory amino acid; Glutamate transport; Phosphatidylinositol 3 kinase; Protein kinase C; Trafficking

Indexed keywords

4 O METHYLPHORBOL 13 ACETATE 12 MYRISTATE; ASPARTIC ACID; CARRIER PROTEIN; CELL SURFACE PROTEIN; EXCITATORY AMINO ACID TRANSPORTER 3; GLUTAMIC ACID; GLYCINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 0032053985     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-07-02475.1998     Document Type: Article
Times cited : (260)

References (53)
  • 1
    • 0030932152 scopus 로고    scopus 로고
    • Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance
    • Arriza JL, Eliasof S, Kavanaugh MP, Amara SG (1997) Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance. Proc Natl Acad Sci USA 94:4155-4160.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4155-4160
    • Arriza, J.L.1    Eliasof, S.2    Kavanaugh, M.P.3    Amara, S.G.4
  • 2
    • 0027376769 scopus 로고
    • Nonvesicular release of neurotransmitter
    • Attwell D, Barbour B, Szatkowski M (1993) Nonvesicular release of neurotransmitter. Neuron 11:401-407.
    • (1993) Neuron , vol.11 , pp. 401-407
    • Attwell, D.1    Barbour, B.2    Szatkowski, M.3
  • 3
    • 0028924892 scopus 로고
    • Presynaptic enhancement of inhibitory synaptic transmission by protein kinase A and C in rat hippocampus in vitro
    • Capogna M, Gahwiler BH, Thompson SM (1995) Presynaptic enhancement of inhibitory synaptic transmission by protein kinase A and C in rat hippocampus in vitro. J Neurosci 15:1249-1260.
    • (1995) J Neurosci , vol.15 , pp. 1249-1260
    • Capogna, M.1    Gahwiler, B.H.2    Thompson, S.M.3
  • 4
    • 0027761918 scopus 로고
    • Phosphorylation and modulation of brain glutamate transporters by protein kinase C
    • Casado M, Bendahan A, Zafra F, Danbolt NC, Gimenez C, Kanner BI (1993) Phosphorylation and modulation of brain glutamate transporters by protein kinase C. J Biol Chem 268:27313-27317.
    • (1993) J Biol Chem , vol.268 , pp. 27313-27317
    • Casado, M.1    Bendahan, A.2    Zafra, F.3    Danbolt, N.C.4    Gimenez, C.5    Kanner, B.I.6
  • 5
    • 0028308412 scopus 로고
    • Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation
    • Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR (1994) Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 14:4902-4911.
    • (1994) Mol Cell Biol , vol.14 , pp. 4902-4911
    • Cheatham, B.1    Vlahos, C.J.2    Cheatham, L.3    Wang, L.4    Blenis, J.5    Kahn, C.R.6
  • 6
    • 0027360635 scopus 로고
    • Protein kinase C α, δ, ε, and ζ in C6 glioma cells: TPA induces translocation and down-regulation of conventional and new PKC isoforms but not atypical PKCζ
    • Chen C-C (1993) Protein kinase C α, δ, ε, and ζ in C6 glioma cells: TPA induces translocation and down-regulation of conventional and new PKC isoforms but not atypical PKCζ. FEBS Lett 332:169-173.
    • (1993) FEBS Lett , vol.332 , pp. 169-173
    • Chen, C.-C.1
  • 8
    • 0031068608 scopus 로고    scopus 로고
    • 2+-independent protein kinase C isoforms may modulate parietal cell HCl secretion
    • 2+-independent protein kinase C isoforms may modulate parietal cell HCl secretion. Am J Physiol 272:G246-G256.
    • (1997) Am J Physiol , vol.272
    • Chew, C.S.1    Zhou, C.J.2    Parente Jr., J.A.3
  • 9
    • 0028260280 scopus 로고
    • Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin
    • Clarke JF, Young PW, Yonezawa K, Kasuea M, Holman GD (1994) Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin. Biochem J 300:631-635.
    • (1994) Biochem J , vol.300 , pp. 631-635
    • Clarke, J.F.1    Young, P.W.2    Yonezawa, K.3    Kasuea, M.4    Holman, G.D.5
  • 10
    • 0026347085 scopus 로고
    • Transmitter release: Target of regulation by protein kinase C?
    • Gispen WH, Routtenberg A, eds. New York: Elsevier Science
    • Dekker LV, De Graan PNE, Gispen WH (1991) Transmitter release: target of regulation by protein kinase C? In: Progress in brain research (Gispen WH, Routtenberg A, eds), pp 209-233. New York: Elsevier Science.
    • (1991) Progress in Brain Research , pp. 209-233
    • Dekker, L.V.1    De Graan, P.N.E.2    Gispen, W.H.3
  • 11
    • 0030900558 scopus 로고    scopus 로고
    • GRIP: A synaptic PDZ domain-containing protein that interacts with AMPA receptors
    • Dong H, O'Brien RJ, Fung ET, Lanahan AA, Worley PF, Huganir RL (1997) GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors. Nature 386:279-284.
    • (1997) Nature , vol.386 , pp. 279-284
    • Dong, H.1    O'Brien, R.J.2    Fung, E.T.3    Lanahan, A.A.4    Worley, P.F.5    Huganir, R.L.6
  • 12
    • 0030036982 scopus 로고    scopus 로고
    • +-dependent L-glutamate transport activity in C6 glioma by phorbol ester
    • +-dependent L-glutamate transport activity in C6 glioma by phorbol ester. J Neurochem 67:508-516.
    • (1996) J Neurochem , vol.67 , pp. 508-516
    • Dowd, L.A.1    Robinson, M.B.2
  • 13
    • 0029921679 scopus 로고    scopus 로고
    • +-dependent glutamate transport activity in synaptosomes, C6 glioma, and Xenopus oocytes expressing excitatory amino acid carrier 1 (EAAC1)
    • +-dependent glutamate transport activity in synaptosomes, C6 glioma, and Xenopus oocytes expressing excitatory amino acid carrier 1 (EAAC1). Mol Pharmacol 49:465-473.
    • (1996) Mol Pharmacol , vol.49 , pp. 465-473
    • Dowd, L.A.1    Coyle, A.J.2    Rothstein, J.D.3    Pritchett, D.B.4    Robinson, M.B.5
  • 14
    • 0029147928 scopus 로고
    • Regulated subcellular distribution of the NR1 subunit of the NMDA receptor
    • Ehlers MD, Tingley WG, Huganir RL (1995) Regulated subcellular distribution of the NR1 subunit of the NMDA receptor. Science 269:1734-1737.
    • (1995) Science , vol.269 , pp. 1734-1737
    • Ehlers, M.D.1    Tingley, W.G.2    Huganir, R.L.3
  • 15
    • 0030014746 scopus 로고    scopus 로고
    • Protein kinase C δ specifically associates with phosphatidylinositol 3-kinase following cytokine stimulation
    • Ettinger SL, Lauener RW, Duronio V (1996) Protein kinase C δ specifically associates with phosphatidylinositol 3-kinase following cytokine stimulation. J Biol Chem 271:14514-14518.
    • (1996) J Biol Chem , vol.271 , pp. 14514-14518
    • Ettinger, S.L.1    Lauener, R.W.2    Duronio, V.3
  • 16
    • 0029076899 scopus 로고
    • An excitatory amino acid transporter with properties of a ligand-gated chloride channel
    • Fairman WA, Vandenberg RJ, Arriza JL, Kavanaugh MP, Amara SG (1995) An excitatory amino acid transporter with properties of a ligand-gated chloride channel. Nature 375:599-603.
    • (1995) Nature , vol.375 , pp. 599-603
    • Fairman, W.A.1    Vandenberg, R.J.2    Arriza, J.L.3    Kavanaugh, M.P.4    Amara, S.G.5
  • 17
    • 0031563761 scopus 로고    scopus 로고
    • Cellular and synaptic localization of the neuronal glutamate transporters EAAT3 and EAAT4
    • Furuta A, Martin LJ, Lin C-LG, Dykes-Hoberg M, Rothstein JD (1997) Cellular and synaptic localization of the neuronal glutamate transporters EAAT3 and EAAT4. Neuroscience 81:1031-1042.
    • (1997) Neuroscience , vol.81 , pp. 1031-1042
    • Furuta, A.1    Martin, L.J.2    Lin, C.-L.G.3    Dykes-Hoberg, M.4    Rothstein, J.D.5
  • 18
    • 0029811866 scopus 로고    scopus 로고
    • Association of phosphatidylinositol 3-kinase to protein kinase Cζ during interleukin-2 stimulation
    • Gomez J, Martinez A-C, Garcia A, Rebollo A (1996) Association of phosphatidylinositol 3-kinase to protein kinase Cζ during interleukin-2 stimulation. Eur J Immunol 26:1781-1787.
    • (1996) Eur J Immunol , vol.26 , pp. 1781-1787
    • Gomez, J.1    Martinez, A.-C.2    Garcia, A.3    Rebollo, A.4
  • 19
    • 0029992108 scopus 로고    scopus 로고
    • Bioenergetics and glutamate excitotoxicity
    • Greene JG, Greenamyre JT (1996) Bioenergetics and glutamate excitotoxicity. Prog Neurobiol 48:613-634.
    • (1996) Prog Neurobiol , vol.48 , pp. 613-634
    • Greene, J.G.1    Greenamyre, J.T.2
  • 21
    • 0028518842 scopus 로고
    • Subcellular localization and trafficking of the GLUT4 glucose transporter isoform in insulin-responsive cells
    • Holman GD, Cushman SW (1994) Subcellular localization and trafficking of the GLUT4 glucose transporter isoform in insulin-responsive cells. BioEssays 16:753-759.
    • (1994) BioEssays , vol.16 , pp. 753-759
    • Holman, G.D.1    Cushman, S.W.2
  • 22
    • 0028023547 scopus 로고
    • Insulin resistance, diabetes, and the insulin-related trafficking of GLUT4
    • James DE, Piper RC (1994) Insulin resistance, diabetes, and the insulin-related trafficking of GLUT4. J Cell Biol 126:1123-1126.
    • (1994) J Cell Biol , vol.126 , pp. 1123-1126
    • James, D.E.1    Piper, R.C.2
  • 23
    • 0026458124 scopus 로고
    • Primary structure and functional characterization of a high-affinity glutamate transporter
    • Kanai Y, Hediger MA (1992) Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 360:467-471.
    • (1992) Nature , vol.360 , pp. 467-471
    • Kanai, Y.1    Hediger, M.A.2
  • 24
    • 0028486018 scopus 로고
    • Phosphatidylinositol 3-kinase
    • Kapeller R, Cantley LC (1994) Phosphatidylinositol 3-kinase. BioEssays 16:565-576.
    • (1994) BioEssays , vol.16 , pp. 565-576
    • Kapeller, R.1    Cantley, L.C.2
  • 25
    • 0030200438 scopus 로고    scopus 로고
    • Heteromultimerization and NMDA receptor-clustering activity of chapsyn-110, a member of the PSD-95 family of proteins
    • Kim E, Cho KO, Rothschild A, Sheng M (1996) Heteromultimerization and NMDA receptor-clustering activity of chapsyn-110, a member of the PSD-95 family of proteins. Neuron 17:103-113.
    • (1996) Neuron , vol.17 , pp. 103-113
    • Kim, E.1    Cho, K.O.2    Rothschild, A.3    Sheng, M.4
  • 26
    • 0027428320 scopus 로고
    • Carrier-mediated release of neurotransmitters
    • Levi G, Raiteri M (1993) Carrier-mediated release of neurotransmitters. Trends Neurosci 16:415-419.
    • (1993) Trends Neurosci , vol.16 , pp. 415-419
    • Levi, G.1    Raiteri, M.2
  • 28
    • 0031029249 scopus 로고    scopus 로고
    • Nuclear translocation of PKCζ during ischemia and its inhibition by wortmannin, an inhibitor of phosphatidylinosilol 3-kinase
    • Mizukami Y, Hirata T, Yoshida K (1997) Nuclear translocation of PKCζ during ischemia and its inhibition by wortmannin, an inhibitor of phosphatidylinosilol 3-kinase. FEBS Lett 401:247-251.
    • (1997) FEBS Lett , vol.401 , pp. 247-251
    • Mizukami, Y.1    Hirata, T.2    Yoshida, K.3
  • 29
    • 0001608898 scopus 로고    scopus 로고
    • MGIuR-mediated increase in cell surface expression of the neuronal glutamate transporter, EAAC1, a possible endogenous mechanism to limit excitotoxicity
    • Munir M, Rothstein JR, Robinson MB (1997) MGIuR-mediated increase in cell surface expression of the neuronal glutamate transporter, EAAC1, a possible endogenous mechanism to limit excitotoxicity. Soc Neurosci Abstr 23:585.9.
    • (1997) Soc Neurosci Abstr , vol.23 , pp. 5859
    • Munir, M.1    Rothstein, J.R.2    Robinson, M.B.3
  • 30
    • 0029159785 scopus 로고
    • Novel functions of phosphatidylinositol 3-kinase in terminally differentiated cells
    • Nakanishi S, Yano H, Matsuda Y (1995) Novel functions of phosphatidylinositol 3-kinase in terminally differentiated cells. Cell Signal 7:545-557.
    • (1995) Cell Signal , vol.7 , pp. 545-557
    • Nakanishi, S.1    Yano, H.2    Matsuda, Y.3
  • 31
    • 0029788522 scopus 로고    scopus 로고
    • Phorbol esters stimulate phosphatidylinositol 3,4,5-triphosphate production on 3T3-L1 adipocytes: Implications for stimulation of glucose transport
    • Navé BT, Siddle K, Shepherd PR (1996) Phorbol esters stimulate phosphatidylinositol 3,4,5-triphosphate production on 3T3-L1 adipocytes: implications for stimulation of glucose transport. Biochem J 318:203-205.
    • (1996) Biochem J , vol.318 , pp. 203-205
    • Navé, B.T.1    Siddle, K.2    Shepherd, P.R.3
  • 32
    • 0030047543 scopus 로고    scopus 로고
    • Calcium movements in traumatic brain injury: The role of glutamate receptor-operated ion channels
    • Nilsson P, Laursen H, Hillered L, Hansen AJ (1996) Calcium movements in traumatic brain injury: the role of glutamate receptor-operated ion channels. J Cereb Blood Flow Metab 16:262-270.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 262-270
    • Nilsson, P.1    Laursen, H.2    Hillered, L.3    Hansen, A.J.4
  • 33
    • 0028122981 scopus 로고
    • Staurosporine inhibits phorbol 12-myristate 13-acetate- And insulin-stimulated translocation of GLUT1 and GLUT4 glucose transporters in rat adipose cells
    • Nishimura H, Simpson IA (1994) Staurosporine inhibits phorbol 12-myristate 13-acetate- and insulin-stimulated translocation of GLUT1 and GLUT4 glucose transporters in rat adipose cells. Biochem J 302:271-277.
    • (1994) Biochem J , vol.302 , pp. 271-277
    • Nishimura, H.1    Simpson, I.A.2
  • 36
    • 0029984610 scopus 로고    scopus 로고
    • Rat C6 and human astrocytic tumor cells express a neuronal type of glutamate transporter
    • Palos TP, Ramachandran B, Boado R, Howard BD (1996) Rat C6 and human astrocytic tumor cells express a neuronal type of glutamate transporter. Mol Brain Res 37:297-303.
    • (1996) Mol Brain Res , vol.37 , pp. 297-303
    • Palos, T.P.1    Ramachandran, B.2    Boado, R.3    Howard, B.D.4
  • 38
    • 0031014266 scopus 로고    scopus 로고
    • Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression
    • Qian Y, Galli A, Ramamoorthy S, Risso S, DeFelice LJ, Blakely RD (1997) Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression. J Neurosci 17:45-57.
    • (1997) J Neurosci , vol.17 , pp. 45-57
    • Qian, Y.1    Galli, A.2    Ramamoorthy, S.3    Risso, S.4    DeFelice, L.J.5    Blakely, R.D.6
  • 39
    • 0030964875 scopus 로고    scopus 로고
    • Second messengers, trafficking-related proteins, and amino acid residues that contribute to the functional regulation of the rat brain GABA transporter GAT1
    • Quick MW, Corey JL, Davidson N, Lester HA (1997) Second messengers, trafficking-related proteins, and amino acid residues that contribute to the functional regulation of the rat brain GABA transporter GAT1. J Neurosci 17:2967-2979.
    • (1997) J Neurosci , vol.17 , pp. 2967-2979
    • Quick, M.W.1    Corey, J.L.2    Davidson, N.3    Lester, H.A.4
  • 40
    • 0011323738 scopus 로고    scopus 로고
    • Heterogeneity and functional properties of subtypes of sodium-dependent glutamate transporters in the mammalian central nervous system
    • Robinson MB, Dowd LA (1997) Heterogeneity and functional properties of subtypes of sodium-dependent glutamate transporters in the mammalian central nervous system [review]. Adv Pharmacol 37:69-115.
    • (1997) Adv Pharmacol , vol.37 , pp. 69-115
    • Robinson, M.B.1    Dowd, L.A.2
  • 41
    • 0026596688 scopus 로고
    • Glutamate uptake disguises neurotoxic potency of glutamate agonists in cerebral cortex in dissociated cell culture
    • Rosenberg PA, Amin S, Leitner M (1992) Glutamate uptake disguises neurotoxic potency of glutamate agonists in cerebral cortex in dissociated cell culture. J Neurosci 12:56-61.
    • (1992) J Neurosci , vol.12 , pp. 56-61
    • Rosenberg, P.A.1    Amin, S.2    Leitner, M.3
  • 43
    • 0029030610 scopus 로고
    • Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
    • Rothstein JD, VanKammen M, Levey AI, Martin LJ, Kuncl RW (1995) Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann Neurol 38:73-84.
    • (1995) Ann Neurol , vol.38 , pp. 73-84
    • Rothstein, J.D.1    Vankammen, M.2    Levey, A.I.3    Martin, L.J.4    Kuncl, R.W.5
  • 45
    • 0024520841 scopus 로고
    • Integral and peripheral protein composition of the apical and basolateral membrane domains in cells
    • Sargiacomo M, Lisanti M, Graeve L, Le Bivic A, Rodriguez-Boulan E (1989) Integral and peripheral protein composition of the apical and basolateral membrane domains in cells. J Membr Biol 107:277-286.
    • (1989) J Membr Biol , vol.107 , pp. 277-286
    • Sargiacomo, M.1    Lisanti, M.2    Graeve, L.3    Le Bivic, A.4    Rodriguez-Boulan, E.5
  • 50
    • 0031031775 scopus 로고    scopus 로고
    • i oscillations in rat glioma cells
    • i oscillations in rat glioma cells. Pflügers Arch 433:312-320.
    • (1997) Pflügers Arch , vol.433 , pp. 312-320
    • Ubl, J.J.1    Reiser, G.2
  • 51
    • 0028238350 scopus 로고
    • Antagonist-dependent and -independent steps in the mechanism of adrenergic receptor internalization
    • Von Zastrow M, Kobilka BK (1994) Antagonist-dependent and -independent steps in the mechanism of adrenergic receptor internalization. J Biol Chem 269:18448-18452.
    • (1994) J Biol Chem , vol.269 , pp. 18448-18452
    • Von Zastrow, M.1    Kobilka, B.K.2
  • 52
    • 0028791442 scopus 로고
    • Biochemical and pharmacological studies with KT7692 and LY294002 on the role of phosphatidylinositol 3-kinase in FcεRI-mediated signal transduction
    • Yano H, Agatsuma T, Nakanishi S, Saitoh Y, Fukui Y, Nonomura Y, Matsuda Y (1995) Biochemical and pharmacological studies with KT7692 and LY294002 on the role of phosphatidylinositol 3-kinase in FcεRI-mediated signal transduction. Biochem J 312:145-150.
    • (1995) Biochem J , vol.312 , pp. 145-150
    • Yano, H.1    Agatsuma, T.2    Nakanishi, S.3    Saitoh, Y.4    Fukui, Y.5    Nonomura, Y.6    Matsuda, Y.7
  • 53
    • 0030922926 scopus 로고    scopus 로고
    • Activation of protein kinase C inhibits uptake, currents, and binding associated with the human dopamine transporter expressed in Xenopus oocytes
    • Zhu SJ, Kavanaugh MP, Sonders MS, Amara SG, Zahniser NR (1997) Activation of protein kinase C inhibits uptake, currents, and binding associated with the human dopamine transporter expressed in Xenopus oocytes. J Pharmacol Exp Ther 282:1358-1365.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 1358-1365
    • Zhu, S.J.1    Kavanaugh, M.P.2    Sonders, M.S.3    Amara, S.G.4    Zahniser, N.R.5


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