Genetic dissection of γ-secretase-dependent and -independent functions of presenilin in regulating neuronal cell cycle and cell death

Journal of Neuroscience

Volumn 28, Issue 44, 2008, Pages 11421-11431

  Kallhoff Munoz, Verena ^a   Hu, Lingyun ^a   Chen, Xiaoli ^a   Pautler, Robia G ^a   Zheng, Hui ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

secretase; Alzheimer's disease; Cell cycle events; Mice; Neurodegeneration; Presenilin

Indexed keywords

CYCLIN D1; GAMMA SECRETASE; GAMMA TUBULIN; NEURON SPECIFIC NUCLEAR PROTEIN; PRESENILIN; PROTEIN P53; QUERCETIN; SECRETASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN SIZE; CELL CYCLE PHASE; CELL CYCLE REGULATION; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; GENE MUTATION; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; ANIMAL; CELL CULTURE; CELL CYCLE; COMPARATIVE STUDY; ENZYMOLOGY; GENE DELETION; GENETICS; HUMAN; MOUSE MUTANT; NERVE CELL; PHYSIOLOGY; TRANSGENIC MOUSE;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CELL CYCLE; CELL DEATH; CELLS, CULTURED; GENE DELETION; HUMANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NEURONS; PRESENILINS;

EID: 56149118152     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2873-08.2008     Document Type: Article

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