Sonic Hedgehog signaling impairs ionizing radiation - Induced checkpoint activation and induces genomic instability

Journal of Cell Biology

Volumn 183, Issue 3, 2008, Pages 385-391

  Leonard, Jennifer M ^a   Ye, Hong ^b   Wetmore, Cynthia ^a,b   Karnitz, Larry M ^a,b  

^a MAYO GRADUATE SCHOOL   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ATR PROTEIN; CHECKPOINT KINASE 1; CLASPIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; CHECKPOINT KINASE 2; GLI PROTEIN, MOUSE; KRUPPEL LIKE FACTOR; PATCHED RECEPTORS; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; SINGLE STRANDED DNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER INHIBITION; EMBRYO; ENZYME ACTIVATION; ENZYME DEFECT; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; IONIZING RADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; CEREBELLUM TUMOR; DNA DAMAGE; GENETICS; MEDULLOBLASTOMA; MOUSE MUTANT; NEOPLASM; PHYSIOLOGY; RADIATION EXPOSURE;

ERINACEIDAE; MUS;

ANIMALS; CEREBELLAR NEOPLASMS; DNA DAMAGE; DNA, SINGLE-STRANDED; GENOMIC INSTABILITY; HEDGEHOG PROTEINS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MEDULLOBLASTOMA; MICE; MICE, KNOCKOUT; NEOPLASMS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RADIATION, IONIZING; RECEPTORS, CELL SURFACE;

EID: 56149098985     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200804042     Document Type: Article

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