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Volumn 72, Issue 6, 2008, Pages 507-516

Impact of cytokine gene polymorphisms on graft-vs-host disease

Author keywords

Cytokine effectors; Genetic polymorphisms; Graft vs host disease

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; CYTOKINE; GAMMA INTERFERON; HLA ANTIGEN CLASS 1; IMMUNOGLOBULIN RECEPTOR; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 6; LYMPHOTOXIN; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR;

EID: 55949126381     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/j.1399-0039.2008.01139.x     Document Type: Review
Times cited : (18)

References (102)
  • 1
    • 0035905908 scopus 로고    scopus 로고
    • Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers
    • Bensinger WI, Martin PJ, Storer B et al. Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers. N Engl J Med 2001 : 344 : 175 81.
    • (2001) N Engl J Med , vol.344 , pp. 175-81
    • Bensinger, W.I.1    Martin, P.J.2    Storer, B.3
  • 3
    • 28344449643 scopus 로고    scopus 로고
    • Acute lung injury after allogeneic stem cell transplantation: From the clinic, to the bench and back again
    • Cooke KR. Acute lung injury after allogeneic stem cell transplantation: from the clinic, to the bench and back again. Pediatr Transplant 2005 : 9 : 25 36.
    • (2005) Pediatr Transplant , vol.9 , pp. 25-36
    • Cooke, K.R.1
  • 4
    • 34547933330 scopus 로고    scopus 로고
    • IFN{gamma} differentially controls the development of idiopathic pneumonia syndrome and GVHD of the gastrointestinal tract
    • Burman AC, Banovic TD, Kuns RD et al. IFN{gamma} differentially controls the development of idiopathic pneumonia syndrome and GVHD of the gastrointestinal tract. Blood 2007 : 110 : 1064 72.
    • (2007) Blood , vol.110 , pp. 1064-72
    • Burman, A.C.1    Banovic, T.D.2    Kuns, R.D.3
  • 5
    • 19344363574 scopus 로고    scopus 로고
    • New approaches for preventing and treating chronic graft-versus-host disease
    • Lee SJ. New approaches for preventing and treating chronic graft-versus-host disease. Blood 2005 : 105 : 4200 6.
    • (2005) Blood , vol.105 , pp. 4200-6
    • Lee, S.J.1
  • 6
    • 0028208934 scopus 로고
    • Effect of total body irradiation, busulfan-cyclophosphamide, or cyclophosphamide conditioning on inflammatory cytokine release and development of acute and chronic graft-versus-host disease in H-2-incompatible transplanted SCID mice
    • Xun CQ, Thompson JS, Jennings CD, Brown SA, Widmer MB. Effect of total body irradiation, busulfan-cyclophosphamide, or cyclophosphamide conditioning on inflammatory cytokine release and development of acute and chronic graft-versus-host disease in H-2-incompatible transplanted SCID mice. Blood 1994 : 83 : 2360 7.
    • (1994) Blood , vol.83 , pp. 2360-7
    • Xun, C.Q.1    Thompson, J.S.2    Jennings, C.D.3    Brown, S.A.4    Widmer, M.B.5
  • 7
    • 0026573134 scopus 로고
    • Macrophage priming and lipopolysaccharide-triggered release of tumor necrosis factor alpha during graft-versus-host disease
    • Nestel FP, Price KS, Seemayer TA, Lapp WS. Macrophage priming and lipopolysaccharide-triggered release of tumor necrosis factor alpha during graft-versus-host disease. J Exp Med 1992 : 175 : 405 13.
    • (1992) J Exp Med , vol.175 , pp. 405-13
    • Nestel, F.P.1    Price, K.S.2    Seemayer, T.A.3    Lapp, W.S.4
  • 8
    • 0024405827 scopus 로고
    • The biology of cachectin/TNF-a primary mediator of the host response
    • Beutler B, Cerami A. The biology of cachectin/TNF-a primary mediator of the host response. Annu Rev Immunol 1989 : 7 : 625 55.
    • (1989) Annu Rev Immunol , vol.7 , pp. 625-55
    • Beutler, B.1    Cerami, A.2
  • 9
    • 0034650697 scopus 로고    scopus 로고
    • The p55 TNFa receptor plays a critical role in T cell alloreactivity
    • Hill GR, Rebel V, Teshima T et al. The p55 TNFa receptor plays a critical role in T cell alloreactivity. J Immunol 2000 : 164 : 656 63.
    • (2000) J Immunol , vol.164 , pp. 656-63
    • Hill, G.R.1    Rebel, V.2    Teshima, T.3
  • 10
    • 0023620524 scopus 로고
    • Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-versus-host disease
    • Piguet PF, Grau GE, Allet B, Vassalli PJ. Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-versus-host disease. J Exp Med 1987 : 166 : 1280 9.
    • (1987) J Exp Med , vol.166 , pp. 1280-9
    • Piguet, P.F.1    Grau, G.E.2    Allet, B.3    Vassalli, P.J.4
  • 11
    • 0030861750 scopus 로고    scopus 로고
    • Total body irradiation and acute graft-versus-host disease: The role of gastrointestinal damage and inflammatory cytokines
    • Hill GR, Crawford JM, Cooke KR, Brinson YS, Pan L, Ferrara JLM. Total body irradiation and acute graft-versus-host disease: the role of gastrointestinal damage and inflammatory cytokines. Blood 1997 : 90 : 3204 13.
    • (1997) Blood , vol.90 , pp. 3204-13
    • Hill, G.R.1    Crawford, J.M.2    Cooke, K.R.3    Brinson, Y.S.4    Pan, L.5    Ferrara, J.L.M.6
  • 12
    • 0032717103 scopus 로고    scopus 로고
    • Differential roles of IL-1 and TNFa on graft-versus-host disease and graft-versus leukemia
    • Hill GR, Teshima T, Gerbita A et al. Differential roles of IL-1 and TNFa on graft-versus-host disease and graft-versus leukemia. J Clin Invest 1999 : 104 : 459 67.
    • (1999) J Clin Invest , vol.104 , pp. 459-67
    • Hill, G.R.1    Teshima, T.2    Gerbita, A.3
  • 13
    • 0025008619 scopus 로고
    • Increased serum levels of tumor necrosis factor alpha precede major complications of bone marrow transplantation
    • Holler E, Kolb HJ, Moller A et al. Increased serum levels of tumor necrosis factor alpha precede major complications of bone marrow transplantation. Blood 1990 : 75 : 1011 6.
    • (1990) Blood , vol.75 , pp. 1011-6
    • Holler, E.1    Kolb, H.J.2    Moller, A.3
  • 14
    • 41349118744 scopus 로고    scopus 로고
    • Etanercept plus methylprednisolone as initial therapy for acute graft-versus-host disease
    • Levine JE, Paczesny S, Mineishi S et al. Etanercept plus methylprednisolone as initial therapy for acute graft-versus-host disease. Blood 2008 : 111 : 2470 5.
    • (2008) Blood , vol.111 , pp. 2470-5
    • Levine, J.E.1    Paczesny, S.2    Mineishi, S.3
  • 15
    • 33745031300 scopus 로고    scopus 로고
    • Combination antithymocyte globulin and soluble TNF[alpha] inhibitor (etanercept) +//- mycophenolate mofetil for treatment of steroid refractory acute graft-versus-host disease
    • Kennedy GA, Butler J, Western R, Morton J, Durrant S, Hill GR. Combination antithymocyte globulin and soluble TNF[alpha] inhibitor (etanercept) +//- mycophenolate mofetil for treatment of steroid refractory acute graft-versus-host disease. Bone Marrow Transplant 2006 : 37 : 1143 7.
    • (2006) Bone Marrow Transplant , vol.37 , pp. 1143-7
    • Kennedy, G.A.1    Butler, J.2    Western, R.3    Morton, J.4    Durrant, S.5    Hill, G.R.6
  • 16
    • 0142054436 scopus 로고
    • Phase I-II trial of a monoclonal anti-tumor necrosis factor alpha antibody for the treatment of refractory severe acute graft-versus-host disease
    • Herve P, Flesch M, Tiberghien P et al. Phase I-II trial of a monoclonal anti-tumor necrosis factor alpha antibody for the treatment of refractory severe acute graft-versus-host disease. Blood 1992 : 81 : 1993 9.
    • (1992) Blood , vol.81 , pp. 1993-9
    • Herve, P.1    Flesch, M.2    Tiberghien, P.3
  • 17
    • 0027762493 scopus 로고
    • Treatment of GVHD-TNF-antibodies and related antagonists
    • Holler E, Kolb HJ, Wilmanns W. Treatment of GVHD-TNF-antibodies and related antagonists. Bone Marrow Transplant 1993 : 3 : 29 31.
    • (1993) Bone Marrow Transplant , vol.3 , pp. 29-31
    • Holler, E.1    Kolb, H.J.2    Wilmanns, W.3
  • 18
    • 37349068567 scopus 로고    scopus 로고
    • Haematopoietic stem cell transplantation: Can our genes predict clinical outcome?
    • Dickinson AM, Harrold JL, Cullup H. Haematopoietic stem cell transplantation: can our genes predict clinical outcome? Expert Rev Mol Med 2007 : 9 : 1 19.
    • (2007) Expert Rev Mol Med , vol.9 , pp. 1-19
    • Dickinson, A.M.1    Harrold, J.L.2    Cullup, H.3
  • 19
    • 0037795749 scopus 로고    scopus 로고
    • Serum levels of cytokines correlate to donor chimerism and acute graft-vs.-host disease after haematopoietic stem cell transplantation
    • Remberger M, Jaksch M, Uzunel M, Mattsson J. Serum levels of cytokines correlate to donor chimerism and acute graft-vs.-host disease after haematopoietic stem cell transplantation. Eur J Haematol 2003 : 70 : 384 91.
    • (2003) Eur J Haematol , vol.70 , pp. 384-91
    • Remberger, M.1    Jaksch, M.2    Uzunel, M.3    Mattsson, J.4
  • 20
    • 0032533678 scopus 로고    scopus 로고
    • Cytokine gene polymorphisms associating with severe acute graft-versus-host disease in HLA-identical sibling transplants
    • Middleton P, Taylor PA, Jackson G, Proctor SJ, Dickinson A. Cytokine gene polymorphisms associating with severe acute graft-versus-host disease in HLA-identical sibling transplants. Blood 1998 : 92 : 3943 8.
    • (1998) Blood , vol.92 , pp. 3943-8
    • Middleton, P.1    Taylor, P.A.2    Jackson, G.3    Proctor, S.J.4    Dickinson, A.5
  • 21
    • 0036456625 scopus 로고    scopus 로고
    • The TNFd4 allele is correlated to moderate-to-severe acute graft-versus-host disease after allogeneic stem cell transplantation
    • Nordlander A, Uzunel M, Mattsson J, Remberger M. The TNFd4 allele is correlated to moderate-to-severe acute graft-versus-host disease after allogeneic stem cell transplantation. Br J Haematol 2002 : 119 : 1133 6.
    • (2002) Br J Haematol , vol.119 , pp. 1133-6
    • Nordlander, A.1    Uzunel, M.2    Mattsson, J.3    Remberger, M.4
  • 22
    • 0035959305 scopus 로고    scopus 로고
    • Both genetic and clinical factors predict the development of graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
    • Socie G, Loiseau P, Tamouza R et al. Both genetic and clinical factors predict the development of graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Transplantation 2001 : 72 : 699 706.
    • (2001) Transplantation , vol.72 , pp. 699-706
    • Socie, G.1    Loiseau, P.2    Tamouza, R.3
  • 23
    • 33744461827 scopus 로고    scopus 로고
    • Association of TNFd and IL-10 polymorphisms with mortality in unrelated hematopoietic stem cell transplantation
    • Bettens F, Passweg J, Gratwohl A et al. Association of TNFd and IL-10 polymorphisms with mortality in unrelated hematopoietic stem cell transplantation. Transplantation 2006 : 81 : 1261 7.
    • (2006) Transplantation , vol.81 , pp. 1261-7
    • Bettens, F.1    Passweg, J.2    Gratwohl, A.3
  • 24
    • 0030954180 scopus 로고    scopus 로고
    • Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation
    • Wilson AG, Symons JA, McDowell TL, McDevitt HO, Duff GW. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci U S A 1997 : 94 : 3195 9.
    • (1997) Proc Natl Acad Sci U S a , vol.94 , pp. 3195-9
    • Wilson, A.G.1    Symons, J.A.2    McDowell, T.L.3    McDevitt, H.O.4    Duff, G.W.5
  • 25
    • 0030704726 scopus 로고    scopus 로고
    • A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • Groux H, O'Garra A, Bigler M et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997 : 389 : 737 42.
    • (1997) Nature , vol.389 , pp. 737-42
    • Groux, H.1    O'Garra, A.2    Bigler, M.3
  • 26
    • 33748162638 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells: Cytokine modulation comes of age
    • Rutella S, Danese S, Leone G. Tolerogenic dendritic cells: cytokine modulation comes of age. Blood 2006 : 108 : 1435 40.
    • (2006) Blood , vol.108 , pp. 1435-40
    • Rutella, S.1    Danese, S.2    Leone, G.3
  • 27
    • 0027281346 scopus 로고
    • Human interleukin-10 can directly inhibit T-cell growth
    • Taga K, Mostowski H, Tosato G. Human interleukin-10 can directly inhibit T-cell growth. Blood 1993 : 81 : 2964 71.
    • (1993) Blood , vol.81 , pp. 2964-71
    • Taga, K.1    Mostowski, H.2    Tosato, G.3
  • 28
    • 0026570853 scopus 로고
    • IL-10 inhibits human T cell proliferation and IL-2 production
    • Taga K, Tosato G. IL-10 inhibits human T cell proliferation and IL-2 production. J Immunol 1992 : 148 : 1143 8.
    • (1992) J Immunol , vol.148 , pp. 1143-8
    • Taga, K.1    Tosato, G.2
  • 30
    • 0028603338 scopus 로고
    • Effects of exogenous interleukin-10 in a murine model of graft-versus-host disease to minor histocompatibility antigens
    • Krenger W, Snyder K, Smith S, Ferrara JLM. Effects of exogenous interleukin-10 in a murine model of graft-versus-host disease to minor histocompatibility antigens. Transplantation 1994 : 58 : 1251 7.
    • (1994) Transplantation , vol.58 , pp. 1251-7
    • Krenger, W.1    Snyder, K.2    Smith, S.3    Ferrara, J.L.M.4
  • 31
    • 0032533769 scopus 로고    scopus 로고
    • Interleukin-10 dose-dependent regulation of CD4+ and CD8+ T cell-mediated graft-versus-host disease
    • Blazar BR, Taylor PA, Panoskaltsis-Mortari A et al. Interleukin-10 dose-dependent regulation of CD4+ and CD8+ T cell-mediated graft-versus-host disease. Transplantation 1998 : 66 : 1220 9.
    • (1998) Transplantation , vol.66 , pp. 1220-9
    • Blazar, B.R.1    Taylor, P.A.2    Panoskaltsis-Mortari, A.3
  • 32
    • 0028898494 scopus 로고
    • Interleukin-10 administration decreases survival in murine recipients of major histocompatibility complex disparate donor bone marrow grafts
    • Blazar BR, Taylor PA, Smith S, Vallera DA. Interleukin-10 administration decreases survival in murine recipients of major histocompatibility complex disparate donor bone marrow grafts. Blood 1995 : 85 : 842 51.
    • (1995) Blood , vol.85 , pp. 842-51
    • Blazar, B.R.1    Taylor, P.A.2    Smith, S.3    Vallera, D.A.4
  • 33
    • 84983719872 scopus 로고    scopus 로고
    • Relation of an interleukin-10 promoter polymorphism to graft-versus-host disease and survival after hematopoietic-cell transplantation
    • Lin MT, Storer B, Martin PJ et al. Relation of an interleukin-10 promoter polymorphism to graft-versus-host disease and survival after hematopoietic-cell transplantation. N Engl J Med 2003 : 349 : 2201 10.
    • (2003) N Engl J Med , vol.349 , pp. 2201-10
    • Lin, M.T.1    Storer, B.2    Martin, P.J.3
  • 34
    • 84983726676 scopus 로고    scopus 로고
    • Genetic variation in the IL-10 pathway modulates severity of acute graft-versus-host disease following hematopoietic cell transplantation: Synergism between IL-10 genotype of patient and IL-10 receptor beta genotype of donor
    • Lin MT, Storer B, Martin PJ et al. Genetic variation in the IL-10 pathway modulates severity of acute graft-versus-host disease following hematopoietic cell transplantation: synergism between IL-10 genotype of patient and IL-10 receptor beta genotype of donor. Blood 2005 : 106 : 3995 4001.
    • (2005) Blood , vol.106 , pp. 3995-4001
    • Lin, M.T.1    Storer, B.2    Martin, P.J.3
  • 35
    • 0345305788 scopus 로고    scopus 로고
    • A protective gene for graft-versus-host disease
    • Cooke KR, Ferrara JL. A protective gene for graft-versus-host disease. N Engl J Med 2003 : 349 : 2183 4.
    • (2003) N Engl J Med , vol.349 , pp. 2183-4
    • Cooke, K.R.1    Ferrara, J.L.2
  • 36
    • 33749358615 scopus 로고    scopus 로고
    • Host B cells produce IL-10 following TBI and attenuate acute GVHD after allogeneic bone marrow transplantation
    • Rowe V, Banovic T, Macdonald KP et al. Host B cells produce IL-10 following TBI and attenuate acute GVHD after allogeneic bone marrow transplantation. Blood 2006 : 108 : 2485 92.
    • (2006) Blood , vol.108 , pp. 2485-92
    • Rowe, V.1    Banovic, T.2    MacDonald, K.P.3
  • 37
    • 0027716849 scopus 로고
    • Interleukin 1 is a critical effector molecule during cytokine dysregulation in graft-versus-host disease to minor histocompatibility antigens
    • Abhyankar S, Gilliland DG, Ferrara JLM. Interleukin 1 is a critical effector molecule during cytokine dysregulation in graft-versus-host disease to minor histocompatibility antigens. Transplantation 1993 : 56 : 1518 23.
    • (1993) Transplantation , vol.56 , pp. 1518-23
    • Abhyankar, S.1    Gilliland, D.G.2    Ferrara, J.L.M.3
  • 38
    • 0002419095 scopus 로고
    • Cytokines as mediators of chronic inflammatory disease
    • In: Kimball, E.S., ed. Boca Raton: CRC Press
    • Dunn CJ. Cytokines as mediators of chronic inflammatory disease. In : Kimball ES, ed. Cytokines and Inflammation. Boca Raton : CRC Press, 1991, 1 35.
    • (1991) Cytokines and Inflammation. , pp. 1-35
    • Dunn, C.J.1
  • 39
    • 0031927564 scopus 로고    scopus 로고
    • IL-1 receptor antagonist (IL-1Ra) plasma levels are co-ordinately regulated by both IL-1Ra and IL-1beta genes
    • Hurme M, Santtila S. IL-1 receptor antagonist (IL-1Ra) plasma levels are co-ordinately regulated by both IL-1Ra and IL-1beta genes. Eur J Immunol 1998 : 28 : 2598 602.
    • (1998) Eur J Immunol , vol.28 , pp. 2598-602
    • Hurme, M.1    Santtila, S.2
  • 40
    • 0026470727 scopus 로고
    • Cytokine receptors: Structure and signal transduction
    • Foxwell BMJ, Barrett K, Feldmann M. Cytokine receptors: structure and signal transduction. Clin Exp Immunol 1992 : 90 : 161 9.
    • (1992) Clin Exp Immunol , vol.90 , pp. 161-9
    • Foxwell, B.M.J.1    Barrett, K.2    Feldmann, M.3
  • 41
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello CA. Biologic basis for interleukin-1 in disease. Blood 1996 : 87 : 2095 147.
    • (1996) Blood , vol.87 , pp. 2095-147
    • Dinarello, C.A.1
  • 42
    • 0027181936 scopus 로고
    • Interleukin-1 type II receptor: A decoy target for IL-1 that is regulated by IL-4
    • Colotta F, Re F, Muzio M et al. Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. Science 1993 : 261 : 472 5.
    • (1993) Science , vol.261 , pp. 472-5
    • Colotta, F.1    Re, F.2    Muzio, M.3
  • 44
    • 0042914300 scopus 로고    scopus 로고
    • Polymorphisms of interleukin-1 alpha constitute independent risk factors for chronic graft-versus-host disease after allogeneic bone marrow transplantation
    • Cullup H, Dickinson AM, Cavet J, Jackson GH, Middleton PG. Polymorphisms of interleukin-1 alpha constitute independent risk factors for chronic graft-versus-host disease after allogeneic bone marrow transplantation. Br J Haematol 2003 : 122 : 778 87.
    • (2003) Br J Haematol , vol.122 , pp. 778-87
    • Cullup, H.1    Dickinson, A.M.2    Cavet, J.3    Jackson, G.H.4    Middleton, P.G.5
  • 45
    • 0028873394 scopus 로고
    • A genetic association between juvenile rheumatoid arthritis and a novel interleukin-1 alpha polymorphism
    • McDowell TL, Symons JA, Ploski R, Forre O, Duff GW. A genetic association between juvenile rheumatoid arthritis and a novel interleukin-1 alpha polymorphism. Arthritis Rheum 1995 : 38 : 221 8.
    • (1995) Arthritis Rheum , vol.38 , pp. 221-8
    • McDowell, T.L.1    Symons, J.A.2    Ploski, R.3    Forre, O.4    Duff, G.W.5
  • 46
    • 0030221694 scopus 로고    scopus 로고
    • An intronic polymorphic repeat sequence modulates interleukin-1 alpha gene regulation
    • Bailly S, Israel N, Fay M, Gougerot-Pocidalo MA, Duff GW. An intronic polymorphic repeat sequence modulates interleukin-1 alpha gene regulation. Mol Immunol 1996 : 33 : 999 1006.
    • (1996) Mol Immunol , vol.33 , pp. 999-1006
    • Bailly, S.1    Israel, N.2    Fay, M.3    Gougerot-Pocidalo, M.A.4    Duff, G.W.5
  • 47
    • 0034994656 scopus 로고    scopus 로고
    • Donor interleukin 1 receptor antagonist genotype associated with acute graft-versus-host disease in human leucocyte antigen-matched sibling allogeneic transplants
    • Cullup H, Dickinson AM, Jackson GH, Taylor PR, Cavet J, Middleton PG. Donor interleukin 1 receptor antagonist genotype associated with acute graft-versus-host disease in human leucocyte antigen-matched sibling allogeneic transplants. Br J Haematol 2001 : 113 : 807 13.
    • (2001) Br J Haematol , vol.113 , pp. 807-13
    • Cullup, H.1    Dickinson, A.M.2    Jackson, G.H.3    Taylor, P.R.4    Cavet, J.5    Middleton, P.G.6
  • 48
    • 0036892525 scopus 로고    scopus 로고
    • Host defense and inflammatory gene polymorphisms are associated with outcomes after HLA-identical sibling bone marrow transplantation
    • Rocha V, Franco RF, Porcher R et al. Host defense and inflammatory gene polymorphisms are associated with outcomes after HLA-identical sibling bone marrow transplantation. Blood 2002 : 100 : 3908 18.
    • (2002) Blood , vol.100 , pp. 3908-18
    • Rocha, V.1    Franco, R.F.2    Porcher, R.3
  • 49
    • 0025986570 scopus 로고
    • Inhibition of interleukin-1 by an interleukin-1 receptor antagonist prevents graft-versus-host disease
    • McCarthy PL, Abhyankar S, Neben S et al. Inhibition of interleukin-1 by an interleukin-1 receptor antagonist prevents graft-versus-host disease. Blood 1991 : 78 : 1915 8.
    • (1991) Blood , vol.78 , pp. 1915-8
    • McCarthy, P.L.1    Abhyankar, S.2    Neben, S.3
  • 50
    • 0028086480 scopus 로고
    • Recombinant human interleukin-1 receptor antagonist in the treatment of steroid-resistant graft-versus-host disease
    • Antin JH, Weinstein HJ, Guinan EC et al. Recombinant human interleukin-1 receptor antagonist in the treatment of steroid-resistant graft-versus-host disease. Blood 1994 : 84 : 1342 8.
    • (1994) Blood , vol.84 , pp. 1342-8
    • Antin, J.H.1    Weinstein, H.J.2    Guinan, E.C.3
  • 51
    • 0037111657 scopus 로고    scopus 로고
    • Interleukin-1 blockade does not prevent acute graft-versus-host disease: Results of a randomized, double-blind, placebo-controlled trial of interleukin-1 receptor antagonist in allogeneic bone marrow transplantation
    • Antin JH, Weisdorf D, Neuberg D et al. Interleukin-1 blockade does not prevent acute graft-versus-host disease: results of a randomized, double-blind, placebo-controlled trial of interleukin-1 receptor antagonist in allogeneic bone marrow transplantation. Blood 2002 : 100 : 3479 82.
    • (2002) Blood , vol.100 , pp. 3479-82
    • Antin, J.H.1    Weisdorf, D.2    Neuberg, D.3
  • 52
    • 0028277663 scopus 로고
    • Unraveling function in the TNF ligand and receptor families
    • Beutler B, van Huffel C. Unraveling function in the TNF ligand and receptor families. Science 1994 : 264 : 667 8.
    • (1994) Science , vol.264 , pp. 667-8
    • Beutler, B.1    Van Huffel, C.2
  • 53
    • 0033787711 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the first intron of the human IFN-[gamma] gene: Absolute correlation with a polymorphic CA microsatellite marker of high IFN-[gamma] production
    • Pravica V, Perrey C, Stevens A, Lee J-H, Hutchinson IV. A single nucleotide polymorphism in the first intron of the human IFN-[gamma] gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-[gamma] production. Hum Immunol 2000 : 61 : 863 6.
    • (2000) Hum Immunol , vol.61 , pp. 863-6
    • Pravica, V.1    Perrey, C.2    Stevens, A.3    Lee, J.-H.4    Hutchinson, I.V.5
  • 54
    • 0035438384 scopus 로고    scopus 로고
    • Interferon-gamma and interleukin-6 gene polymorphisms associate with graft-versus-host disease in HLA-matched sibling bone marrow transplantation
    • Cavet J, Dickinson AM, Norden J, Taylor PR, Jackson GH, Middleton PG. Interferon-gamma and interleukin-6 gene polymorphisms associate with graft-versus-host disease in HLA-matched sibling bone marrow transplantation. Blood 2001 : 98 : 1594 600.
    • (2001) Blood , vol.98 , pp. 1594-600
    • Cavet, J.1    Dickinson, A.M.2    Norden, J.3    Taylor, P.R.4    Jackson, G.H.5    Middleton, P.G.6
  • 55
    • 0029084805 scopus 로고
    • Interleukin-6 family of cytokines and gp130
    • Kishimoto T, Akira S, Narazaki M, Taga T. Interleukin-6 family of cytokines and gp130. Blood 1995 : 86 : 1243 54.
    • (1995) Blood , vol.86 , pp. 1243-54
    • Kishimoto, T.1    Akira, S.2    Narazaki, M.3    Taga, T.4
  • 56
    • 0026485304 scopus 로고
    • Interleukin-6 and its receptor: A paradigm for cytokines
    • Kishimoto T, Akira S, Taga T. Interleukin-6 and its receptor: a paradigm for cytokines. Science 1992 : 258 : 593 7.
    • (1992) Science , vol.258 , pp. 593-7
    • Kishimoto, T.1    Akira, S.2    Taga, T.3
  • 57
    • 21544462602 scopus 로고    scopus 로고
    • IL-6 and IL-10 promoter gene polymorphisms of patients and donors of allogeneic sibling hematopoietic stem cell transplants associate with the risk of acute graft-versus-host disease
    • Karabon L, Wysoczanska B, Bogunia-Kubik K, Suchnicki K, Lange A. IL-6 and IL-10 promoter gene polymorphisms of patients and donors of allogeneic sibling hematopoietic stem cell transplants associate with the risk of acute graft-versus-host disease. Hum Immunol 2005 : 66 : 700 10.
    • (2005) Hum Immunol , vol.66 , pp. 700-10
    • Karabon, L.1    Wysoczanska, B.2    Bogunia-Kubik, K.3    Suchnicki, K.4    Lange, A.5
  • 58
    • 0032189103 scopus 로고    scopus 로고
    • The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis
    • Fishman D, Faulds G, Jeffery R et al. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 1998 : 102 : 1369 76.
    • (1998) J Clin Invest , vol.102 , pp. 1369-76
    • Fishman, D.1    Faulds, G.2    Jeffery, R.3
  • 59
    • 0029937270 scopus 로고    scopus 로고
    • Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
    • Kaplan MH, Sun Y-L, Hoey T, Grusby MJ. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 1996 : 382 : 174 7.
    • (1996) Nature , vol.382 , pp. 174-7
    • Kaplan, M.H.1    Sun, Y.-L.2    Hoey, T.3    Grusby, M.J.4
  • 60
    • 0033490502 scopus 로고    scopus 로고
    • Interleukin-12: A cytokine at the interface of inflammation and immunity
    • Trinchieri G. Interleukin-12: a cytokine at the interface of inflammation and immunity. Adv Immunol 1998 : 70 : 83 243.
    • (1998) Adv Immunol , vol.70 , pp. 83-243
    • Trinchieri, G.1
  • 61
    • 0030267472 scopus 로고    scopus 로고
    • IL-12 p40 message RNA expression in target organs during acute graft-versus-host disease. Possible involvement of IFN-gamma
    • Kichian K, Nestel FP, Kim D, Ponka P, Lapp WS. IL-12 p40 message RNA expression in target organs during acute graft-versus-host disease. Possible involvement of IFN-gamma. J Immunol 1996 : 157 : 2851 6.
    • (1996) J Immunol , vol.157 , pp. 2851-6
    • Kichian, K.1    Nestel, F.P.2    Kim, D.3    Ponka, P.4    Lapp, W.S.5
  • 62
    • 0032079469 scopus 로고    scopus 로고
    • Interleukin-12 inhibits graft-versus-host disease through an Fas- mediated mechanism associated with alterations in donor T-cell activation and expansion
    • Dey BR, Yang YG, Szot GL, Pearson DA, Sykes M. Interleukin-12 inhibits graft-versus-host disease through an Fas- mediated mechanism associated with alterations in donor T-cell activation and expansion. Blood 1998 : 91 : 3315 22.
    • (1998) Blood , vol.91 , pp. 3315-22
    • Dey, B.R.1    Yang, Y.G.2    Szot, G.L.3    Pearson, D.A.4    Sykes, M.5
  • 63
    • 0035914735 scopus 로고    scopus 로고
    • Interleukin-18 regulates acute graft-versus-host disease by enhancing Fas-mediated donor T cell apoptosis
    • Reddy P, Teshima T, Kukuruga M et al. Interleukin-18 regulates acute graft-versus-host disease by enhancing Fas-mediated donor T cell apoptosis. J Exp Med 2001 : 194 : 1433 40.
    • (2001) J Exp Med , vol.194 , pp. 1433-40
    • Reddy, P.1    Teshima, T.2    Kukuruga, M.3
  • 64
    • 0038784377 scopus 로고    scopus 로고
    • Pretreatment of donors with interleukin-18 attenuates acute graft-versus-host disease via STAT6 and preserves graft-versus-leukemia effects
    • Reddy P, Teshima T, Hildebrandt G et al. Pretreatment of donors with interleukin-18 attenuates acute graft-versus-host disease via STAT6 and preserves graft-versus-leukemia effects. Blood 2003 : 101 : 2877 85.
    • (2003) Blood , vol.101 , pp. 2877-85
    • Reddy, P.1    Teshima, T.2    Hildebrandt, G.3
  • 65
    • 33646560950 scopus 로고    scopus 로고
    • Transforming growth factor-[beta] induces development of the TH17 lineage
    • Mangan PR, Harrington LE, O'Quinn DB et al. Transforming growth factor-[beta] induces development of the TH17 lineage. Nature 2006 : 441 : 231 4.
    • (2006) Nature , vol.441 , pp. 231-4
    • Mangan, P.R.1    Harrington, L.E.2    O'Quinn, D.B.3
  • 66
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli E, Carrier Y, Gao W et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006 : 441 : 235 8.
    • (2006) Nature , vol.441 , pp. 235-8
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3
  • 67
    • 32244442562 scopus 로고    scopus 로고
    • TGF[beta] in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B. TGF[beta] in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006 : 24 : 179 89.
    • (2006) Immunity , vol.24 , pp. 179-89
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 68
    • 45749101727 scopus 로고    scopus 로고
    • Induction and effector functions of TH17 cells
    • Bettelli E, Korn T, Oukka M, Kuchroo VK. Induction and effector functions of TH17 cells. Nature 2008 : 453 : 1051 7.
    • (2008) Nature , vol.453 , pp. 1051-7
    • Bettelli, E.1    Korn, T.2    Oukka, M.3    Kuchroo, V.K.4
  • 69
    • 34248572345 scopus 로고    scopus 로고
    • T(H)-17 cells in the circle of immunity and autoimmunity
    • Bettelli E, Oukka M, Kuchroo VK. T(H)-17 cells in the circle of immunity and autoimmunity. Nat Immunol 2007 : 8 : 345 50.
    • (2007) Nat Immunol , vol.8 , pp. 345-50
    • Bettelli, E.1    Oukka, M.2    Kuchroo, V.K.3
  • 70
    • 27544465354 scopus 로고    scopus 로고
    • A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
    • Park H, Li Z, Yang XO et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 2005 : 6 : 1133 41.
    • (2005) Nat Immunol , vol.6 , pp. 1133-41
    • Park, H.1    Li, Z.2    Yang, X.O.3
  • 71
    • 36248965294 scopus 로고    scopus 로고
    • TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology
    • McGeachy MJ, Bak-Jensen KS, Chen Y et al. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology. Nat Immunol 2007 : 8 : 1390 7.
    • (2007) Nat Immunol , vol.8 , pp. 1390-7
    • McGeachy, M.J.1    Bak-Jensen, K.S.2    Chen, Y.3
  • 72
    • 39449110445 scopus 로고    scopus 로고
    • The link between IL-23 and Th17 cell-mediated immune pathologies
    • McGeachy MJ, Cua DJ. The link between IL-23 and Th17 cell-mediated immune pathologies. Semin Immunol 2007 : 19 : 372 6.
    • (2007) Semin Immunol , vol.19 , pp. 372-6
    • McGeachy, M.J.1    Cua, D.J.2
  • 73
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington LE, Hatton RD, Mangan PR et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005 : 6 : 1123 32.
    • (2005) Nat Immunol , vol.6 , pp. 1123-32
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3
  • 74
    • 33747777440 scopus 로고    scopus 로고
    • Cutting edge: IL-23 cross-regulates IL-12 production in T cell-dependent experimental colitis
    • Becker C, Dornhoff H, Neufert C et al. Cutting edge: IL-23 cross-regulates IL-12 production in T cell-dependent experimental colitis. J Immunol 2006 : 177 : 2760 4.
    • (2006) J Immunol , vol.177 , pp. 2760-4
    • Becker, C.1    Dornhoff, H.2    Neufert, C.3
  • 75
    • 52649136967 scopus 로고    scopus 로고
    • Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft versus host disease
    • Yi T, Zhao D, Lin CL et al. Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft versus host disease. Blood 2008 : 2 : 2.
    • (2008) Blood , vol.22
    • Yi, T.1    Zhao, D.2    Lin, C.L.3
  • 76
    • 33745082823 scopus 로고    scopus 로고
    • Role of transforming growth factor-beta in hematologic malignancies
    • Dong M, Blobe GC. Role of transforming growth factor-beta in hematologic malignancies. Blood 2006 : 107 : 4589 96.
    • (2006) Blood , vol.107 , pp. 4589-96
    • Dong, M.1    Blobe, G.C.2
  • 78
    • 0038044861 scopus 로고    scopus 로고
    • IL-10 and TGF-{beta} induce alloreactive CD4+CD25- T cells to acquire regulatory cell function
    • Chen Z-M, O'Shaughnessy MJ, Gramaglia I et al. IL-10 and TGF-{beta} induce alloreactive CD4+CD25- T cells to acquire regulatory cell function. Blood 2003 : 101 : 5076 83.
    • (2003) Blood , vol.101 , pp. 5076-83
    • Chen, Z.-M.1    O'Shaughnessy, M.J.2    Gramaglia, I.3
  • 79
    • 0036372440 scopus 로고    scopus 로고
    • Transforming growth factor-beta in T-cell biology
    • Gorelik L, Flavell RA. Transforming growth factor-beta in T-cell biology. Nat Rev Immunol 2002 : 2 : 46 53.
    • (2002) Nat Rev Immunol , vol.2 , pp. 46-53
    • Gorelik, L.1    Flavell, R.A.2
  • 80
    • 0033213948 scopus 로고    scopus 로고
    • Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta
    • Zeller JC, Panoskaltsis-Mortari A, Murphy WJ et al. Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta. J Immunol 1999 : 163 : 3684 91.
    • (1999) J Immunol , vol.163 , pp. 3684-91
    • Zeller, J.C.1    Panoskaltsis-Mortari, A.2    Murphy, W.J.3
  • 81
    • 1242267910 scopus 로고    scopus 로고
    • CD4+ and CD8+ regulatory T cells generated ex vivo with IL-2 and TGF-beta suppress a stimulatory graft-versus-host disease with a lupus-like syndrome
    • Zheng SG, Wang JH, Koss MN, Quismorio F Jr., Gray JD, Horwitz DA. CD4+ and CD8+ regulatory T cells generated ex vivo with IL-2 and TGF-beta suppress a stimulatory graft-versus-host disease with a lupus-like syndrome. J Immunol 2004 : 172 : 1531 9.
    • (2004) J Immunol , vol.172 , pp. 1531-9
    • Zheng, S.G.1    Wang, J.H.2    Koss, M.N.3    Quismorio Jr., F.4    Gray, J.D.5    Horwitz, D.A.6
  • 82
    • 24744447794 scopus 로고    scopus 로고
    • TGF-{beta} in allogeneic stem cell transplantation: Friend or foe?
    • Banovic T, MacDonald KPA, Morris ES et al. TGF-{beta} in allogeneic stem cell transplantation: friend or foe? Blood 2005 : 106 : 2206 14.
    • (2005) Blood , vol.106 , pp. 2206-14
    • Banovic, T.1    MacDonald, K.P.A.2    Morris, E.S.3
  • 83
    • 0036861905 scopus 로고    scopus 로고
    • Polymorphisms of transforming growth factor-beta1 and transforming growth factor-beta1 type II receptor genes are associated with acute graft-versus-host disease in children with HLA-matched sibling bone marrow transplantation
    • Hattori H, Matsuzaki A, Suminoe A et al. Polymorphisms of transforming growth factor-beta1 and transforming growth factor-beta1 type II receptor genes are associated with acute graft-versus-host disease in children with HLA-matched sibling bone marrow transplantation. Bone Marrow Transplant 2002 : 30 : 665 71.
    • (2002) Bone Marrow Transplant , vol.30 , pp. 665-71
    • Hattori, H.1    Matsuzaki, A.2    Suminoe, A.3
  • 84
    • 0036222293 scopus 로고    scopus 로고
    • Relevance of KIR gene polymorphisms in bone marrow transplantation outcome
    • Gagne K, Brizard G, Gueglio B et al. Relevance of KIR gene polymorphisms in bone marrow transplantation outcome. Hum Immunol 2002 : 63 : 271 80.
    • (2002) Hum Immunol , vol.63 , pp. 271-80
    • Gagne, K.1    Brizard, G.2    Gueglio, B.3
  • 85
    • 0033168770 scopus 로고    scopus 로고
    • Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation
    • Ruggeri L, Capanni M, Casucci M et al. Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation. Blood 1999 : 94 : 333 9.
    • (1999) Blood , vol.94 , pp. 333-9
    • Ruggeri, L.1    Capanni, M.2    Casucci, M.3
  • 86
    • 0031944075 scopus 로고    scopus 로고
    • NK cell receptors
    • Lanier LL. NK cell receptors. Annu Rev Immunol 1998 : 16 : 359 93.
    • (1998) Annu Rev Immunol , vol.16 , pp. 359-93
    • Lanier, L.L.1
  • 87
    • 0036222654 scopus 로고    scopus 로고
    • A structural perspective on MHC class I recognition by killer cell immunoglobulin-like receptors
    • Boyington JC, Sun PD. A structural perspective on MHC class I recognition by killer cell immunoglobulin-like receptors. Mol Immunol 2002 : 38 : 1007 21.
    • (2002) Mol Immunol , vol.38 , pp. 1007-21
    • Boyington, J.C.1    Sun, P.D.2
  • 89
    • 0037086131 scopus 로고    scopus 로고
    • Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
    • Ruggeri L, Capanni M, Urbani E et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 2002 : 295 : 2097 100.
    • (2002) Science , vol.295 , pp. 2097-100
    • Ruggeri, L.1    Capanni, M.2    Urbani, E.3
  • 90
    • 34347396957 scopus 로고    scopus 로고
    • Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: Challenging its predictive value
    • Ruggeri L, Mancusi A, Capanni M et al. Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: challenging its predictive value. Blood 2007 : 110 : 433 40.
    • (2007) Blood , vol.110 , pp. 433-40
    • Ruggeri, L.1    Mancusi, A.2    Capanni, M.3
  • 91
    • 34247581578 scopus 로고    scopus 로고
    • Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GVHD) following unrelated donor allogeneic HCT
    • Miller JS, Cooley S, Parham P et al. Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GVHD) following unrelated donor allogeneic HCT. Blood 2007 : 109 : 5058 61.
    • (2007) Blood , vol.109 , pp. 5058-61
    • Miller, J.S.1    Cooley, S.2    Parham, P.3
  • 92
    • 0023697978 scopus 로고
    • Tumor necrosis factor can induce both apoptotic and necrotic forms of cell lysis
    • Laster SM, Wood JG, Gooding LR. Tumor necrosis factor can induce both apoptotic and necrotic forms of cell lysis. J Immunol 1988 : 141 : 2629.
    • (1988) J Immunol , vol.141 , pp. 2629
    • Laster, S.M.1    Wood, J.G.2    Gooding, L.R.3
  • 94
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
    • Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med 1994 : 179 : 1109 18.
    • (1994) J Exp Med , vol.179 , pp. 1109-18
    • Sallusto, F.1    Lanzavecchia, A.2
  • 95
    • 0036281797 scopus 로고    scopus 로고
    • Acute graft-versus-host disease does not require alloantigen expression on host epithelium
    • Teshima T, Ordemann R, Reddy P et al. Acute graft-versus-host disease does not require alloantigen expression on host epithelium. Nat Med 2002 : 8 : 575 81.
    • (2002) Nat Med , vol.8 , pp. 575-81
    • Teshima, T.1    Ordemann, R.2    Reddy, P.3
  • 96
    • 0344140225 scopus 로고
    • Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition
    • Okusawa S, Gelfand JA, Ikejima T, Connolly RJ, Dinarello CA. Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition. J Clin Invest 1988 : 81 : 1162.
    • (1988) J Clin Invest , vol.81 , pp. 1162
    • Okusawa, S.1    Gelfand, J.A.2    Ikejima, T.3    Connolly, R.J.4    Dinarello, C.A.5
  • 97
    • 0023181249 scopus 로고
    • Tumor necrosis factor and interleukin 1: Cytokines with multiple overlapping biological activities
    • Le J, Vilcek J. Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities. Lab Invest 1987 : 56 : 234.
    • (1987) Lab Invest , vol.56 , pp. 234
    • Le, J.1    Vilcek, J.2
  • 98
    • 0030044284 scopus 로고    scopus 로고
    • Interleukins 6 and 11 protect mice from mortality in a staphylococcal enterotoxin-induced toxic shock model
    • Barton BE, Shortall J, Jackson JV. Interleukins 6 and 11 protect mice from mortality in a staphylococcal enterotoxin-induced toxic shock model. Infection and Immunity 1996 : 64 : 714 8.
    • (1996) Infection and Immunity , vol.64 , pp. 714-8
    • Barton, B.E.1    Shortall, J.2    Jackson, J.V.3
  • 99
    • 5644277476 scopus 로고    scopus 로고
    • Interleukin-17 Family Members and Inflammation
    • Kolls JK, Lindén A. Interleukin-17 Family Members and Inflammation. Immunity 2004 : 21 : 467 76.
    • (2004) Immunity , vol.21 , pp. 467-76
    • Kolls, J.K.1    Lindén, A.2
  • 100
    • 1842376280 scopus 로고    scopus 로고
    • High interleukin-10 serum levels are associated with fatal outcome in patients after bone marrow transplantation
    • Hempel L, Korholz D, Nussbaum P, Bonig H, Burdach S, Zintl F. High interleukin-10 serum levels are associated with fatal outcome in patients after bone marrow transplantation. Bone Marrow Transplant 1997 : 20 : 365 8.
    • (1997) Bone Marrow Transplant , vol.20 , pp. 365-8
    • Hempel, L.1    Korholz, D.2    Nussbaum, P.3    Bonig, H.4    Burdach, S.5    Zintl, F.6
  • 101
    • 47549112840 scopus 로고    scopus 로고
    • IL-21 and TGF-beta are required for differentiation of human T(H)17 cells
    • Yang L, Anderson DE, Baecher-Allan C et al. IL-21 and TGF-beta are required for differentiation of human T(H)17 cells. Nature 2008 : 454 : 350 2.
    • (2008) Nature , vol.454 , pp. 350-2
    • Yang, L.1    Anderson, D.E.2    Baecher-Allan, C.3
  • 102
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-{beta} induction of transcription factor Foxp3
    • Chen W, Jin W, Hardegen N et al. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-{beta} induction of transcription factor Foxp3. J Exp Med 2003 : 198 : 1875 86.
    • (2003) J Exp Med , vol.198 , pp. 1875-86
    • Chen, W.1    Jin, W.2    Hardegen, N.3


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