Respiratory syncytial virus infection of human respiratory epithelial cells enhances inducible nitric oxide synthase gene expression

Journal of Leukocyte Biology

Volumn 66, Issue 1, 1999, Pages 99-104

  Tsutsumi, Hiroyuki ^a   Takeuchi, Ryoh ^b   Ohsaki, Masaya ^b   Seki, Kimihira ^b   Chiba, Shunzo ^b  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NONE

Author keywords

Human type 2 alveolar epithelial cells (A549 cells); Inducible nitric oxide synthase; Interferon regulatory factor 1; Interferons; Interleukin 1 ; Tumor necrosis factor

Indexed keywords

BETA INTERFERON; CYTOKINE; GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 1; MESSENGER RNA; NEUTRALIZING ANTIBODY; NITRIC OXIDE SYNTHASE; NITRITE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BRONCHIOLITIS; CASE REPORT; CHILD; CONTROLLED STUDY; ENZYME INDUCTION; GENE EXPRESSION; HUMAN; HUMAN CELL; INFANT; KINETICS; LUNG ALVEOLUS EPITHELIUM; PRESCHOOL CHILD; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; TRANSCRIPTION INITIATION; VIRUS INFECTION; VIRUS PATHOGENESIS;

ALPHAVIRUS; RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS; SYNCYTIAL VIRUS;

EID: 0032990672     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.66.1.99     Document Type: Article

References (38)

1. Collins, P. L., McIntosh, K., Chanock, R. M. (1996) Respiratory syncytial virus In Fields Virology, 3rd ed. (B. N. Fields and D. M. Knie, eds.) New York: Raven Press, 1313-1351.
2. Denny, F. W., Clynde, W. A. (1986) Acute lower respiratory tract infections in nonhospitalized children. J. Pediatr. 108, 635-646.
3. MacDonald, N. E., Hall, C. B., Suffin, S. C., Alexson, C., Harris, P. J., Manning, J. A, (1982) Respiratory syncytial viral infection in infants with congenital heart disease. N. Engl. J. Med. 307, 397-400.
4. Neilson, K. A., Yunis, E. J. (1990) Demonstration of respiratory syncytial virus in an autopsy series. Pediatr. Pathol. 10, 491-502.
5. Matsuda, K., Tsutsumi, H., Okamoto, Y., Chiba, S. (1995) Development of interleukin 6 and tumor necrosis factor alpha activity in nasopharyngeal secretion of infants and children during infections with respiratory syncytial virus. Clin. Diag. Lab. Immunol. 2, 322-324.
6. Noah, T. L. Henderson, F. W., Wortman, I. A., Devlin, R. B., Handy, J., Koren, H. S., Becker, S. (1995) Nasal cytokine production in viral acute upper respiratory infection of childhood. J. Infect. Dis. 171, 584-592.
7. Becker, S., Quay, J., Soukup, J. (1991) Cytokine (tumor necrosis factor, IL-6 and IL-8) production by respiratory syncytial virus-infected human alveolar macrophages. J. Immunol. 147, 4307-4312.
8. Matsuda, K., Tsutsumi, H., Sone, S., Yoto,Y., Oya, K., Okamoto, Y., Ogra, P. L., Chiba, S. (1996) Characteristics of IL-6 and TNF-α production by respiratory syncytial virus-infected macrophages in the neonate. J. Med. Virol. 48, 199-203.
9. Olszewska-Pazdrak, B., Casola, A., Saito, T., Alam, R., Crowe, S. E., Mei, F., Ogra, P. L., Garofaro, R. (1998) Cell-specific expressioin of RANTES, MCP-1, and MIP-1α by lower airway epithelial cells and eosinophils infected with respiratory syncytial virus. J. Virol. 72, 4756-4764.
10. Takeuchi, R., Tsutsumi, H., Osaki, M., Sone, S., Imai, S., Chiba, S. (1998) Respiratory syncytial virus infection of neonatal monocytes stimulates synthesis of interferon regulatory factor 1 and interleukin-1 (IL-1)-β converting enzyme and secretion of IL-1β. J. Virol. 72, 837-840.
11. Nathan, C., Xie, Q. (1994) Nitric oxide synthases: roles, tolls, and controls. Cell 78, 915-918.
12. Asano, K., Chee, C. B. E., Gaston, B., Lilly, C. M., Gerard, C., Drazen, J. M., Stamler, J. T. (1994) Constitutive and inducible nitric oxide synthases gene expression, regulation, and activity in human lung epithelial cells. Proc. Natl. Acad. Sci. USA 91, 10089-10093.
13. Shaul, P. W., North, A. J., Wu, L. C., Wells, L. B., Brannon, T. S., Lau, K. S., Michel, T., Margraf, L. R., Star, R. A. (1994) Endothelial nitric oxide synthase is expressed in cultured human bronchiolar epithelium. J. Clin. Invest. 94, 2231-2236.
14. Guo, F. H., De Raeve, H. R., Rice, T. W., Stuehr, D. J., Thunnissen, F. B. J. M., Erzurum, S. C. (1995) Continuous nitric oxide synthase by inducible nitric oxide synthase in normal human airway epithelium in vivo. Proc. Natl. Acad. Sci. USA 92, 7809-7813.
15. Watkins, D. N., Peroni, D. P., Basclain, K. A., Garlepp, M. J., Thompson, P. J. (1997) Expression and activity of nitric oxide synthases in human airway epithelium. Am. J. Respir. Cell Mol. Biol. 16, 629-639.
16. Akaike, T., Noguchi, Y., Ijiri, S., Setoguchi, K., Suga, M., Zheng, Y. M., Dietzschold, B., Maeda, H. (1996) Pathogenesis of influenza virus-induced pneumonia: Involvement of both nitric oxide and oxygen radicals. Proc. Natl. Acad. Sci. USA 93, 2448-2453.
17. Akaike, T., Maeda, H. (1998) Free radicals in viral pathogenesis: molecular mechanisms involving superoxide and NO. Proc. Soc. Exp. Biol. Med. 217, 64-73.
18. Lopez-Guerrero, J. A., Carrasco, L. (1998) Effect of nitric oxide on poliovirus infection of two human cell lines. J. Virol. 72, 2538-2540.
19. Majano, P. L., Garcia-Monzon, C., Lopez-Cabrera, M., Lara-Pezzi, E., Fernandez-Rulz, E., Garcia-Iglesias, C., Borque, M. J., Moreno-Otero, R. (1998) Inducible nitric oxide sythase expression in chronic viral hepatitis, evidence for a virus-induced gene upregulation. J. Clin. Invest. 101, 1343-1352.
20. Goldring, C. E. P., Narayanan, R., Lagadec, P., Jeannin, J-F. (1995) Transcriptional inhibition of the inducible nitric oxide synthase gene by competitive binding of NF-κB/Rel proteins. Biochem. Biophys. Res. Commun. 209, 73-79.
21. Kimura, T., Nakayama, K., Penninger, J., Kitagawa, M., Harada, H., Matsuyama, T., Tanaka, N., Kamijo, R., Vilcek, J., Mak, T. W., Taniguchi, T. (1994) Involvement of the IRF-1 transcription factor in antiviral responses to interferons. Science 264, 1921-1924.
22. Kamijo, R., Harada, H., Matsuyama, T., Bosland, M., Gerecitano, J., Shapiro, D., Le, J., Koh, S. I., Kimura, T., Green, S. J., Mak, T. W., Taniguchi, T., Vilcek, J. (1994) Requirement of transcriptional factor IRF-1 in NO synthase induction in macrophages. Science 263, 1612-1615.
23. Takeuchi, R., Tsutsumi, H., Osaki, M., Haseyama, K., Mizue, N., Chiba, S. (1998) Respiratory syncytial virus infection of human alveolar epithelial cells enhances interferon regulatory factor 1 and interleukin-1β-converting enzyme gene expression but does not cause apoptosis. J. Virol. 72, 4498-4502.
24. Sone, S., Tsutsumi, H., Takeuchi, R., Matsuda, K., Imai, S., Ogra, P. L., Chiba, S. (1997) Enhanced cytokine production by milk macrophages following infection with respiratory syncytial virus. J. Leukoc. Biol. 61, 630-636.
25. Charles, L. G., Palmer, R. M., Hickery, M. S., Bayliss, M. T., Chubb, A. P., Hall, V. S., Moss, D. W., Moncada, S. (1993) Cloning, characterization, and expression of a cDNA encoding an inducible nitric oxide synthase from the human chondrocyte. Proc. Natl. Acad. Sci. USA 90, 11419-11423.
26. Green, L. C., Wagner, D. A., Glogowski, L., Skipper, P. L., Wishnok, J. S., Tannenbaum, S. R. (1982) Analysis of nitrate, nitrite and 15N nitrate in biological fluids. Anal. Biochem. 126, 131-138.
27. Zheng, Y. M., Schofer, M. K. H., Weihe, E., Sheng, H., Corisdeo, S., Fu, J. F., Koprorwski, H., Dietzschold, B. (1993) Severity of neurological signs and degree of inflammatory lesions in the brains of the rats with Borna disease correlate with the induction of nitric oxide synthase. J. Virol. 67, 5786-5791.
28. Akaike, T., Weihe, E., Schaefer, M., Fu, Z. F., Zheng, Y. M., Vogel, W., Schmidt, H., Koprowski, H., Dietzschold, B. (1995) Effect of neurotropic virus infection on neuronal and inducible nitric oxide synthase activity in rat brain. J. Neurovirol. 1, 118-125.
29. Karupiah, G., Xie, Q. W., Buller, R. M., Nathan, C., Duarte, C., MacMicking, J. D. (1993) Inhibition of viral replication by interferon-γ-induced nitric oxide synthase. Science 261, 1445-1448.
30. Harris, N., Buller, R. M. L., Karupiah, G. (1995) Gamma interferon-induced, nitric oxide-mediated inhibition of vaccinia virus replication. J. Virol. 69, 910-915.
31. Komatsu, T., Bi, Z., Reiss, C. S. (1996) Interferon-γ induced type 1 nitric oxide synthase activity inhibits viral replication in neurons. J. Neuroimmunol. 68, 101-108.
32. Adlerr, H., Beland, J. L., Del-Pan, N. C., Kobzik, L., Brewer, J. P., Martin, T. R., Rimm, I. J. (1997) Suppression of herpes simplex virus type 1 (HSV-1)-induced pneumonia in mice by inhibition of inducible nitric oxide synthase (iNOS, NOS2). J. Exp. Med. 185, 1533-1540.
33. Zaragoza, C., Ocampo, C. J., Saura, M., McMillan, A., Lowenstein, C. L. (1997) Nitric oxide inhibition of coxackie virus replication in vitro. J. Clin. Invest. 100, 1760-1767.
34. Sanders, S. P., Sierkieski, E. S., Porter, J, D., Richards, S. M., Proud, D. (1998) Nitric oxide inhibits rhinovirus-induced cytokine production and viral replication in human respiratory epithelial cell line. J. Virol. 72, 934-942.
35. Reiss, C. H., Komatsu, T. (1998) Does nitric oxide play a critical role in viral infection? J. Virol. 72, 4547-4551.
36. Miyamoto, M., Fujita, T., Kimura, Y., Maruyama, M., Harada, H., Sudo, Y., Miyata, T., Taniguchi, T. (1988) Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements. Cell 54, 903-913.
37. Tamura, T., Ishihara, M., Lamphier, M. S., Tanaka, N., Oishi, I., Aizawa, S., Matsuyama, T., Mak, T. W., Taki, S., Taniguchi, T. (1996) An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes. Nature 376, 596-599.
38. Furchgott, R. F., Zawadzki, J. V. (1980) The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288, 373-376.