Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 29, 2005, Pages 10200-10205

  Zhao, Chen ^a   Denison, Carilee ^b   Huibregtse, Jon M ^a   Gygi, Steven ^b   Krug, Robert M ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Antiviral; Innate immunity; Mass spectroscopy

Indexed keywords

ALPHA INTERFERON; ANTIVIRUS PROTEIN; BETA INTERFERON; DNA DIRECTED DNA POLYMERASE ALPHA; HUP56 PROTEIN; INTERFERON; ISG15 PROTEIN; MYXOVIRUS RESISTANCE PROTEIN A; PKR PROTEIN; PROTEIN; RIG 1 PROTEIN; UBCH8 PROTEIN; UBE1L PROTEIN; UBIQUITIN; UBIQUITIN LIKE PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL INFECTION; CELL FUNCTION; CELL METABOLISM; CELL SELECTION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONJUGATION; CYTOSKELETON; DOUBLE AFFINITY SELECTION; GENETIC TRANSCRIPTION; HELA CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLUENZA VIRUS B; INNATE IMMUNITY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PURIFICATION; PROTEIN TARGETING; RNA SPLICING; RNA TRANSLATION; STRESS; TECHNIQUE; VIRUS INFECTION;

ANTIVIRAL AGENTS; CYTOKINES; DEAD-BOX RNA HELICASES; EIF-2 KINASE; GTP-BINDING PROTEINS; HELA CELLS; HUMANS; IMMUNITY, NATURAL; INFLUENZA B VIRUS; INTERFERON TYPE I; MASS SPECTROMETRY; RNA HELICASES; UBIQUITIN-ACTIVATING ENZYMES; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINS;

INFLUENZA B VIRUS;

EID: 22544487172     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0504754102     Document Type: Article

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