Type II pneumocyte-CD8+ T-cell interactions relationship between target cell cytotoxicity and activation

American Journal of Respiratory Cell and Molecular Biology

Volumn 25, Issue 3, 2001, Pages 362-369

  Zhao, M Q ^a   Amir, M K ^a   Rice, W R ^a   Enelow, R I ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; INFLUENZA VIRUS; INFLUENZAVIRUS A;

EID: 0034808106     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.25.3.4476     Document Type: Article

References (43)

1. Distinct types of lung disease caused by functional subsets of antiviral T cells
2. To kill or to cure: Options in host defense against viral infection
3. Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo
4. Immunopathological mechanisms in respiratory syncytial virus disease
5. Alveolar epithelial cell chemokine expression triggered by antigen-specific cytolytic CD8+ T cell recognition
6. Experimental T cell-mediated lung disease: Structural and functional consequences of alveolar cell recognition by CD8+ T lymphocytes
7. Perforin-independent cytotoxicity in T cell-mediated cytotoxicity of alveolar epithelial cells is preferentially mediated by tumor necrosis factor-α: Relative insensitivity to Fas ligand
8. A novel addition to the T cell repertory. Cell surface expression of tumor necrosis factor/cachectin by activated normal human T cells
9. In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis
10. A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF
11. Use of antiviral T-lymphocyte clones to characterize antigen presentation and T-lymphocyte subsets
12. Immune function in mice lacking the perforin gene
13. A lung-specific neo-antigen elicits specific CD8+ T cell tolerance with preserved CD4+ T cell reactivity
14. Isolation and primary culture of murine alveolar type II cells
15. The cell-mediated and humorat responses to influenza virus infection in the mouse lung
16. Role of viral infectivity in the induction of influenza virus-specific cytotoxic T cells
17. CD4+ and CD8+ cytolytic T lymphocyte recognition of viral antigens
18. Viral antigen presentation and MHC assembly
19. Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis
20. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
21. Mechanism of lymphocyte-mediated cytolysis: Functional cytolytic T cells lacking perforin and granzymes
22. Partial activation of CD8+ T cells by a self-derived peptide
23. Selective activation of Fas/Fas ligand-mediated cytotoxicity by a self peptide
24. T cell receptor antagonist peptides induce positive selection
25. Respiratory syncytial virus increases IL-8 gene expression and protein release in A549 cells
26. Initial and innate responses to viral infections - Pattern setting in immunity or disease
27. Protective heterologous antiviral immunity and enhanced immunopathogenesis mediated by memory T cell populations
28. Virus-specific CD8+ T cells in primary and secondary influenza pneumonia
29. Resistance of CTL to perforin-mediated lysis. Evidence for a lymphocyte membrane protein interacting with perforin
30. Selective regulation of apoptosis: The cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway
31. A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes
32. Monocyte chemotactic protein expression during schistosome egg granuloma formation. Sequence of production, localization, contribution, and regulation
33. Involvement of the IP-10 chemokine in sarcoid granulomatous reactions
34. The CXC chemokines, IL-8 and IP-10, regulate angiogenic activity in idiopathic pulmonary fibrosis
35. Neutralization of the CXC chemokine, macrophage inflammatory protein-2, attenuates bleomycin-induced pulmonary fibrosis
36. IFN-gamma-inducible protein-10 attenuates Neomycin-induced pulmonary fibrosis via inhibition of angiogenesis
37. Monocyte chemoattractant protein-1 synthesis by murine lung fibroblasts modulates CD4+ T cell activation
38. C-C chemokines: Novel mediators of the profibrotic response to Neomycin challenge
39. Fas and perforin as major mechanisms of T cell-mediated cytotoxicity
40. The role of the Fas lytic pathway in a perforin-less CTL hybridoma
41. CD8+ T cells clear influenza virus by perforin or Fas-dependent processes
42. The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 Kda tumor necrosis factor receptor
43. Regulated commitment of TNF receptor signaling: A molecular switch for death or activation