-
1
-
-
0035735902
-
Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways
-
Rommel, C. et al. Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways. Nature Cell Biol. 3, 1009-1013 (2001).
-
(2001)
Nature Cell Biol.
, vol.3
, pp. 1009-1013
-
-
Rommel, C.1
-
2
-
-
0035736260
-
Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo
-
Bodine, S. C. et al. Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nature Cell Biol. 3, 1014-1019 (2001).
-
(2001)
Nature Cell Biol.
, vol.3
, pp. 1014-1019
-
-
Bodine, S.C.1
-
3
-
-
0037047098
-
A protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification
-
Pallafacchina, G., Calabria, E., Serrano, A. L., Kalhovde, J. M. & Schiaffino, S. A protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification. Proc. Natl. Acad. Sci. USA 99, 9213-9218 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9213-9218
-
-
Pallafacchina, G.1
Calabria, E.2
Serrano, A.L.3
Kalhovde, J.M.4
Schiaffino, S.5
-
4
-
-
0348110375
-
IGF-II transcription in skeletal myogenesis is controlled by mTOR and nutrients
-
Erbay, E., Park, I. H., Nuzzi, P. D., Schoenherr, C. J. & Chen, J. IGF-II transcription in skeletal myogenesis is controlled by mTOR and nutrients. J. Cell Biol. 163, 931-936 (2003).
-
(2003)
J. Cell Biol.
, vol.163
, pp. 931-936
-
-
Erbay, E.1
Park, I.H.2
Nuzzi, P.D.3
Schoenherr, C.J.4
Chen, J.5
-
5
-
-
11144356337
-
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
-
Sandri, M. et al. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 117, 399-412 (2004).
-
(2004)
Cell
, vol.117
, pp. 399-412
-
-
Sandri, M.1
-
6
-
-
2042425906
-
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
-
Stitt, T. N. et al. The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol. Cell 14, 395-403 (2004).
-
(2004)
Mol. Cell
, vol.14
, pp. 395-403
-
-
Stitt, T.N.1
-
7
-
-
0041424822
-
Molecular mechanisms modulating muscle mass
-
Glass, D. J. Molecular mechanisms modulating muscle mass. Trends Mol. Med. 9, 344-350 (2003).
-
(2003)
Trends Mol. Med.
, vol.9
, pp. 344-350
-
-
Glass, D.J.1
-
8
-
-
0037020044
-
Identification of TOR signaling complexes: More TORC for the cell growth engine
-
Abraham, R. T. Identification of TOR signaling complexes: more TORC for the cell growth engine. Cell 111, 9-12 (2002).
-
(2002)
Cell
, vol.111
, pp. 9-12
-
-
Abraham, R.T.1
-
10
-
-
0030934472
-
The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways
-
Coolican, S. A., Samuel, D. S., Ewton, D. Z., McWade, F. J. & Florini, J. R. The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways. J. Biol. Chem. 272, 6653-6662 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6653-6662
-
-
Coolican, S.A.1
Samuel, D.S.2
Ewton, D.Z.3
McWade, F.J.4
Florini, J.R.5
-
11
-
-
0038094504
-
Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1)
-
Huang, S. et al. Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1). Mol. Cell 11, 1491-1501 (2003).
-
(2003)
Mol. Cell
, vol.11
, pp. 1491-1501
-
-
Huang, S.1
-
12
-
-
0032843917
-
Drosophila S6 kinase: A regulator of cell size
-
Montagne, J. et al. Drosophila S6 kinase: a regulator of cell size. Science 285, 2126-2129 (1999).
-
(1999)
Science
, vol.285
, pp. 2126-2129
-
-
Montagne, J.1
-
13
-
-
0034312315
-
Regulation of cellular growth by the Drosophila target of rapamycin dTOR
-
Zhang, H., Stallock, J. P., Ng, J. C., Reinhard, C. & Neufeld, T. P. Regulation of cellular growth by the Drosophila target of rapamycin dTOR. Genes Dev. 14, 2712-2724 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 2712-2724
-
-
Zhang, H.1
Stallock, J.P.2
Ng, J.C.3
Reinhard, C.4
Neufeld, T.P.5
-
14
-
-
0034976004
-
The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila
-
Miron, M. et al. The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila. Nature Cell Biol. 3, 596-601 (2001).
-
(2001)
Nature Cell Biol.
, vol.3
, pp. 596-601
-
-
Miron, M.1
-
15
-
-
0037097863
-
Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
-
Fingar, D. C., Salama, S., Tsou, C., Harlow, E. & Blenis, J. Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E. Genes Dev. 16, 1472-1487 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 1472-1487
-
-
Fingar, D.C.1
Salama, S.2
Tsou, C.3
Harlow, E.4
Blenis, J.5
-
16
-
-
0345732640
-
mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E
-
Fingar, D. C. et al. mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E. Mol. Cell. Biol. 24, 200-216 (2004).
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 200-216
-
-
Fingar, D.C.1
-
17
-
-
11144356304
-
-/-) Mice exhibit perinatal lethality and rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway
-
-/-) Mice exhibit perinatal lethality and rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway. Mol. Cell. Biol. 24, 3112-3124 (2004).
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 3112-3124
-
-
Pence, M.1
-
18
-
-
0034700456
-
Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice
-
Pende, M. et al. Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice. Nature 408, 994-997 (2000).
-
(2000)
Nature
, vol.408
, pp. 994-997
-
-
Pende, M.1
-
19
-
-
0035498939
-
Hierarchical phosphorylation of the translation inhibitor 4E-BP1
-
Gingras, A. C. et al. Hierarchical phosphorylation of the translation inhibitor 4E-BP1. Genes Dev. 15, 2852-2864 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 2852-2864
-
-
Gingras, A.C.1
-
20
-
-
0037600600
-
Role of Akt/protein kinase B in metabolism
-
Whiteman, E. L., Cho, H. & Birnbaum, M. J. Role of Akt/protein kinase B in metabolism. Trends Endocrinol. Metab 13, 444-451 (2002).
-
(2002)
Trends Endocrinol. Metab.
, vol.13
, pp. 444-451
-
-
Whiteman, E.L.1
Cho, H.2
Birnbaum, M.J.3
-
22
-
-
0038579284
-
Differences in the way a mammalian cell and yeast cells coordinate cell growth and cell-cycle progression
-
Conlon, I. & Raff, M. Differences in the way a mammalian cell and yeast cells coordinate cell growth and cell-cycle progression. J. Biol. 2, 7 (2003).
-
(2003)
J. Biol.
, vol.2
, pp. 7
-
-
Conlon, I.1
Raff, M.2
-
23
-
-
4444297122
-
Evidence for a size-sensing mechanism in animal cells
-
Dolznig, H., Grebien, F., Sauer, T., Beug, H. & Mullner, E. W. Evidence for a size-sensing mechanism in animal cells. Nature Cell Biol. 6, 899-905 (2004).
-
(2004)
Nature Cell Biol.
, vol.6
, pp. 899-905
-
-
Dolznig, H.1
Grebien, F.2
Sauer, T.3
Beug, H.4
Mullner, E.W.5
-
24
-
-
0032538890
-
Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase
-
Shima, H. et al. Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase. EMBO J. 17, 6649-6659 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 6649-6659
-
-
Shima, H.1
-
25
-
-
0003936739
-
-
(ed. Celis, J.) (Academic, New York)
-
Pinset, C. & Montarras, D. in Cell Biology, a Laboratory Handbook (ed. Celis, J.) 226-232 (Academic, New York, 1998).
-
(1998)
Cell Biology, a Laboratory Handbook
, pp. 226-232
-
-
Pinset, C.1
Montarras, D.2
|