Inhibition of stearoyl-CoA desaturase 1 expression in human lung adenocarcinoma cells impairs tumorigenesis

International Journal of Oncology

Volumn 33, Issue 4, 2008, Pages 839-850

  Scaglia, Natalia ^a,b   Igal, R Ariel ^b  

^a INSTITUTO DE INVESTIGACIONES BIOQUÍMICAS DE LA PLATA INIBIOLP   (Argentina)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Akt pathway; Cell proliferation; Human cancer cells; Monounsaturated fatty acid synthesis; Tumor formation

Indexed keywords

ACYL COENZYME A DESATURASE; ACYL COENZYME A DESATURASE 1; GLYCOGEN SYNTHASE KINASE 3BETA; ISOENZYME; MONOUNSATURATED FATTY ACID; OLEIC ACID; PROTEIN KINASE B; SATURATED FATTY ACID; SERINE; UNCLASSIFIED DRUG;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; FEMALE; GENE EXPRESSION REGULATION; GROWTH RATE; HUMAN; HUMAN CELL; IN VIVO STUDY; LIPID ANALYSIS; LUNG ADENOCARCINOMA; LUNG CARCINOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TUMOR XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIPIDS; LUNG NEOPLASMS; MICE; MICE, NUDE; OLEIC ACID; PHENOTYPE; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS C-AKT; STEAROYL-COA DESATURASE;

EID: 54049084951     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo_00000072     Document Type: Article

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