Inactivation of ErbB3 by siRNA promotes apoptosis and attenuates growth and invasiveness of human lung adenocarcinoma cell line A549

Oncogene

Volumn 24, Issue 11, 2005, Pages 1847-1859

  Sithanandam, Gunamani ^a   Fornwald, Laura W ^a   Fields, Janet ^b   Anderson, Lucy M ^b  

^a SAIC FREDERICK INC   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Akt; Apoptosis; ErbB3; Invasion; Lung adenocarcinoma; SiRNA

Indexed keywords

AGAR; EPIDERMAL GROWTH FACTOR RECEPTOR 3; ISOPROTEIN; PROTEIN KINASE B; PROTEIN KINASE B BETA; PROTEIN KINASE B1; PROTEIN KINASE B3; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; AKT1 PROTEIN, HUMAN; AKT2 PROTEIN, HUMAN; ONCOPROTEIN; PRIMER DNA; PROTEIN SERINE THREONINE KINASE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CELL COUNT; CELL CYCLE; CELL DIVISION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ADENOCARCINOMA; DRUG ANTAGONISM; GENETICS; LUNG TUMOR; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ADENOCARCINOMA; APOPTOSIS; BASE SEQUENCE; CELL DIVISION; CELL LINE, TUMOR; CELL SURVIVAL; DNA PRIMERS; HUMANS; LUNG NEOPLASMS; NEOPLASM INVASIVENESS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, ERBB-3; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 16244409820     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208381     Document Type: Article

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