Modulation of proteinase K-resistant prion protein in cells and infectious brain homogenate by redox iron: Implications for prion replication and disease pathogenesis

Molecular Biology of the Cell

Volumn 18, Issue 9, 2007, Pages 3302-3312

  Basu, Subhabrata ^a   Mohan, Maradumane L ^a   Luo, Xiu ^a   Kundu, Bishwajit ^b   Kong, Qingzhong ^a   Singh, Neena ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

Author keywords

[No Author keywords available]

Indexed keywords

FERROUS ION; PRION PROTEIN; PRION PROTEIN SCRAPIE; PROTEINASE K; UNCLASSIFIED DRUG;

AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BETA SHEET; BRAIN HOMOGENATE; CELL CULTURE; CELL LYSATE; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IRON METABOLISM; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; OXIDATION REDUCTION REACTION; PATHOGENESIS; PRION DISEASE; PRIORITY JOURNAL; PROTEIN BINDING;

AGED; ANIMALS; BRAIN; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; DEFEROXAMINE; ENDOPEPTIDASE K; FERRIC COMPOUNDS; FERRITINS; HUMANS; IRON; MICE; MIDDLE AGED; OXIDATION-REDUCTION; PRION DISEASES; PROTEIN CONFORMATION; PRPC PROTEINS; PRPSC PROTEINS; TISSUE EXTRACTS;

EID: 34548512806     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E07-04-0317     Document Type: Article

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