-
1
-
-
0034916581
-
Prion diseases of humans and animals: Their causes and molecular basis
-
Collinge, J. Prion diseases of humans and animals: Their causes and molecular basis. Annu. Rev. Neurosci. 24, 519-550 (2001).
-
(2001)
Annu. Rev. Neurosci
, vol.24
, pp. 519-550
-
-
Collinge, J.1
-
3
-
-
0342951746
-
A new variant of Creutzfeldt-Jakob disease in the UK
-
Will, R.G. et al. A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 347, 921-925 (1996).
-
(1996)
Lancet
, vol.347
, pp. 921-925
-
-
Will, R.G.1
-
4
-
-
0033600407
-
Variant Creutzfeldt-Jakob disease
-
Collinge, J. Variant Creutzfeldt-Jakob disease. Lancet354, 317-323 (1999).
-
(1999)
Lancet
, vol.354
, pp. 317-323
-
-
Collinge, J.1
-
5
-
-
0000049491
-
Experimental transmission of trembling to the goat
-
Cullie, J. & Chelle, P.L. Experimental transmission of trembling to the goat. C. R. Seances Acad. Sci. 208, 1058-1160 (1939).
-
(1939)
C. R. Seances Acad. Sci
, vol.208
, pp. 1058-1160
-
-
Cullie, J.1
Chelle, P.L.2
-
6
-
-
49749206702
-
Encephalopathy in mice produced by inoculation with scrapie brain material
-
Chandler, R.L. Encephalopathy in mice produced by inoculation with scrapie brain material. Lancet 1, 1378-1379 (1961).
-
(1961)
Lancet
, vol.1
, pp. 1378-1379
-
-
Chandler, R.L.1
-
7
-
-
0014021742
-
Experimental transmission of a Kuru-like syndrome to chimpanzees
-
Gajdusek, D.C., Gibbs, C.J. & Alpers, M. Experimental transmission of a Kuru-like syndrome to chimpanzees. Nature 209, 794-796 (1966).
-
(1966)
Nature
, vol.209
, pp. 794-796
-
-
Gajdusek, D.C.1
Gibbs, C.J.2
Alpers, M.3
-
8
-
-
0014430962
-
Creutzfeldt-Jakob disease (Spongiform encephalopathy): Transmission to the chimpanzee
-
Gibbs, C.J. Jr et al. Creutzfeldt-Jakob disease (spongiform encephalopathy): Transmission to the chimpanzee. Science 161, 388-389 (1968).
-
(1968)
Science
, vol.161
, pp. 388-389
-
-
Gibbs, C.J.1
-
9
-
-
0019778656
-
Creutzfeldt-Jakob disease virus isolations from the Gerstmann-Straussler syndrome with an analysis of the various forms of amyloid plaque deposition in the virus-induced spongiform encephalopathies
-
Masters, C.L., Gajdusek, D.C. & Gibbs, C.J., Jr. Creutzfeldt-Jakob disease virus isolations from the Gerstmann-Straussler syndrome with an analysis of the various forms of amyloid plaque deposition in the virus-induced spongiform encephalopathies. Brain 104, 559-588 (1981).
-
(1981)
Brain
, vol.104
, pp. 559-588
-
-
Masters, C.L.1
Gajdusek, D.C.2
Gibbs, C.J.3
-
10
-
-
0017063432
-
Is the scrapie agent a virus?
-
Cho, H.J. Is the scrapie agent a virus? Nature 262, 411-412 (1976).
-
(1976)
Nature
, vol.262
, pp. 411-412
-
-
Cho, H.J.1
-
11
-
-
0014211846
-
Does the agent of scrapie replicate without nucleic acid?
-
Alper, T., Cramp, W.A., Haig, D.A. & Clarke, M.C. Does the agent of scrapie replicate without nucleic acid? Nature214, 764-766 (1967).
-
(1967)
Nature
, vol.214
, pp. 764-766
-
-
Alper, T.1
Cramp, W.A.2
Haig, D.A.3
Clarke, M.C.4
-
12
-
-
0014004625
-
The exceptionally small size of the scrapie agent. Biochem. Biophys
-
Alper, T., Haig, D.A. & Clarke, M.C. The exceptionally small size of the scrapie agent. Biochem. Biophys. Res. Commun. 22, 278-284 (1966).
-
(1966)
Res. Commun
, vol.22
, pp. 278-284
-
-
Alper, T.1
Haig, D.A.2
Clarke, M.C.3
-
13
-
-
0020481648
-
Scrapie agent: Prions or virinos?
-
Kimberlin, R.H. Scrapie agent: Prions or virinos? Nature 297, 107-108 (1982).
-
(1982)
Nature
, vol.297
, pp. 107-108
-
-
Kimberlin, R.H.1
-
14
-
-
0014190760
-
Self-replication and scrapie
-
Griffith, J.S. Self-replication and scrapie. Nature 215, 1043-1044 (1967).
-
(1967)
Nature
, vol.215
, pp. 1043-1044
-
-
Griffith, J.S.1
-
15
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
Prusiner, S.B. Novel proteinaceous infectious particles cause scrapie. Science 216, 136-144 (1982).
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
16
-
-
0020490156
-
Identification of a protein that purifies with the scrapie prion
-
Bolton, D.C., McKinley, M.P. & Prusiner, S.B. Identification of a protein that purifies with the scrapie prion. Science 218, 1309-1311 (1982).
-
(1982)
Science
, vol.218
, pp. 1309-1311
-
-
Bolton, D.C.1
McKinley, M.P.2
Prusiner, S.B.3
-
17
-
-
0003279877
-
Immunoaffinity purification and neutralization of scrapie prion infectivity
-
Gabizon, R., McKinley, M.P., Groth, D. & Prusiner, S.B. Immunoaffinity purification and neutralization of scrapie prion infectivity. Proc. Natl. Acad. Sci. USA 85, 6617-6621 (1988).
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 6617-6621
-
-
Gabizon, R.1
McKinley, M.P.2
Groth, D.3
Prusiner, S.B.4
-
18
-
-
0035979274
-
Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody
-
Enari, M., Flechsig, E. & Weissmann, C. Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody. Proc. Natl. Acad. Sci. USA 98, 9295-9299 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9295-9299
-
-
Enari, M.1
Flechsig, E.2
Weissmann, C.3
-
19
-
-
0035899413
-
Antibodies inhibit prion propagation and clear cell cultures of prion infectivity
-
Peretz, D. et al. Antibodies inhibit prion propagation and clear cell cultures of prion infectivity. Nature412, 739-743 (2001).
-
(2001)
Nature
, vol.412
, pp. 739-743
-
-
Peretz, D.1
-
20
-
-
0022005315
-
A cellular gene encodes scrapie PrP 27-30 protein
-
Oesch, B. et al. A cellular gene encodes scrapie PrP 27-30 protein. Cell 40, 735-746 (1985).
-
(1985)
Cell
, vol.40
, pp. 735-746
-
-
Oesch, B.1
-
21
-
-
0021884354
-
Identification of scrapie prion protein-specific mRNA in scrapie- infected and uninfected brain
-
Chesebro, B. et al. Identification of scrapie prion protein-specific mRNA in scrapie- infected and uninfected brain. Nature 315, 331-333 (1985).
-
(1985)
Nature
, vol.315
, pp. 331-333
-
-
Chesebro, B.1
-
22
-
-
0027534612
-
Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing
-
Stahl, N. et al. Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing. Biochemistry 32, 1991-2002 (1993).
-
(1993)
Biochemistry
, vol.32
, pp. 1991-2002
-
-
Stahl, N.1
-
23
-
-
0027332116
-
Conversion of a-helices into p-sheets features in the formation of scrapie prion poteins
-
Pan, K.M. et al. Conversion of a-helices into p-sheets features in the formation of scrapie prion poteins. Proc. Natl. Acad. Sci. USA 90, 10962-10966 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10962-10966
-
-
Pan, K.M.1
-
24
-
-
0025681138
-
Spontaneous neurodegeneration in transgenic mice with mutant prion protein
-
Hsiao, K.K. et al. Spontaneous neurodegeneration in transgenic mice with mutant prion protein. Science 250, 1587-1590 (1990).
-
(1990)
Science
, vol.250
, pp. 1587-1590
-
-
Hsiao, K.K.1
-
25
-
-
0028608963
-
Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein
-
Hsiao, K.K. et al. Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein. Proc. Natl. Acad. Sci. USA 91, 9126-9130 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9126-9130
-
-
Hsiao, K.K.1
-
26
-
-
0037366956
-
Gene-targeted mouse model of P102L Gerstmann- Straussler-Scheinker syndrome
-
Barron, R.M. & Manson, J.C. A gene-targeted mouse model of P102L Gerstmann- Straussler-Scheinker syndrome. Clin. Lab. Med. 23, 161-173 (2003).
-
(2003)
Clin. Lab. Med
, vol.23
, pp. 161-173
-
-
Barron, R.M.1
Manson, J.2
-
27
-
-
0027319326
-
Mice devoid of PrP are resistant to Scrapie
-
Bueler, H. et al. Mice devoid of PrP are resistant to Scrapie. Cell 73, 1339-1347 (1993).
-
(1993)
Cell
, vol.73
, pp. 1339-1347
-
-
Bueler, H.1
-
28
-
-
0021745705
-
In vitro replication of scrapie agent in a neuronal model: Infection of PC12 cells
-
Rubenstein, R., Carp, R.I. & Callahan, S.M. In vitro replication of scrapie agent in a neuronal model: Infection of PC12 cells. J. Gen. Virol. 65, 2191-2198 (1984).
-
(1984)
J. Gen. Virol
, vol.65
, pp. 2191-2198
-
-
Rubenstein, R.1
Carp, R.I.2
Callahan, S.M.3
-
29
-
-
0023091197
-
Characterization of scrapie infection in mouse neuroblastoma cells
-
Race, R.E., Fadness, L.H. & Chesebro, B. Characterization of scrapie infection in mouse neuroblastoma cells. J. Gen. Virol. 68, 1391-1399 (1987).
-
(1987)
J. Gen. Virol
, vol.68
, pp. 1391-1399
-
-
Race, R.E.1
Fadness, L.H.2
Chesebro, B.3
-
30
-
-
0027956109
-
Cell-free formation of protease-resistant prion protein
-
Kocisko, D.A. et al. Cell-free formation of protease-resistant prion protein. Nature 370, 471-474 (1994).
-
(1994)
Nature
, vol.370
, pp. 471-474
-
-
Kocisko, D.A.1
-
31
-
-
0035859102
-
Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding
-
Saborio, G.P., Permanne, B. & Soto, C. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 411, 810-813 (2001).
-
(2001)
Nature
, vol.411
, pp. 810-813
-
-
Saborio, G.P.1
Permanne, B.2
Soto, C.3
-
32
-
-
0032472239
-
BSE and prions: Uncertainties about the agent
-
Chesebro, B. BSE and prions: Uncertainties about the agent. Science 279, 42-43 (1998).
-
(1998)
Science
, vol.279
, pp. 42-43
-
-
Chesebro, B.1
-
33
-
-
0031720905
-
Eight prion strains have PrP(Sc) molecules with different conformations
-
Safar, J. et al. Eight prion strains have PrP(Sc) molecules with different conformations. Nat. Med. 4, 1157-1165 (1998).
-
(1998)
Nat. Med
, vol.4
, pp. 1157-1165
-
-
Safar, J.1
-
34
-
-
0033610870
-
Strain-dependent differences in p- sheet conformations of abnormal prion protein
-
Caughey, B., Raymond, G.J. & Bessen, R.A. Strain-dependent differences in p- sheet conformations of abnormal prion protein. J. Biol. Chem. 273, 32230-32235 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 32230-32235
-
-
Caughey, B.1
Raymond, G.J.2
Bessen, R.A.3
-
35
-
-
0028997297
-
Non-genetic propagation of strain-specific properties of scrapie prion protein
-
Bessen, R.A. et al. Non-genetic propagation of strain-specific properties of scrapie prion protein. Nature 375, 698-700 (1995).
-
(1995)
Nature
, vol.375
, pp. 698-700
-
-
Bessen, R.A.1
-
36
-
-
0344030333
-
Transmission of the BSE agent to mice in the absence of detectable abnormal prion protein
-
Lasmezas, C.I. et al. Transmission of the BSE agent to mice in the absence of detectable abnormal prion protein. Science275, 402-405 (1997).
-
(1997)
Science
, vol.275
, pp. 402-405
-
-
Lasmezas, C.I.1
-
37
-
-
0034730170
-
Species-barrier-independent prion replication in apparently resistant species
-
Hill, A.F. et al. Species-barrier-independent prion replication in apparently resistant species. Proc. Natl. Acad. Sci. USA 97, 10248-10253 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10248-10253
-
-
Hill, A.F.1
-
38
-
-
0036375067
-
A critical review of the nature of the spongiform encephalopathy agent: Protein theory versus virus theory
-
Narang, H. A critical review of the nature of the spongiform encephalopathy agent: Protein theory versus virus theory. Exp. Biol. Med. 227, 4-19 (2002).
-
(2002)
Exp. Biol. Med
, vol.227
, pp. 4-19
-
-
Narang, H.1
-
39
-
-
0030843497
-
RNA aptamers specifically interact with the prion protein PrP
-
Weiss, S. et al. RNA aptamers specifically interact with the prion protein PrP. J. Virol. 71, 8790-8797 (1997).
-
(1997)
J. Virol
, vol.71
, pp. 8790-8797
-
-
Weiss, S.1
-
40
-
-
0036371353
-
PrPC has nucleic acid chaperoning properties similar to the nucleocapsid protein of HIV-1
-
Derrington, E. et al. PrPC has nucleic acid chaperoning properties similar to the nucleocapsid protein of HIV-1. C. R. Acad. Sci. III 325, 17-23 (2002).
-
(2002)
C. R. Acad. Sci. III
, vol.325
, pp. 17-23
-
-
Derrington, E.1
-
41
-
-
0142184333
-
RNA molecules stimulate prion protein conversion
-
Deleault, N.R., Lucassen, R.W. & Supattapone, S. RNA molecules stimulate prion protein conversion. Nature 425, 717-720 (2003).
-
(2003)
Nature
, vol.425
, pp. 717-720
-
-
Deleault, N.R.1
Lucassen, R.W.2
Supattapone, S.3
-
42
-
-
0037264120
-
Unfolding the role of protein misfolding in neurodegenerative diseases
-
Soto, C. Unfolding the role of protein misfolding in neurodegenerative diseases. Nat. Rev. Neurosci. 4, 49-60 (2003).
-
(2003)
Nat. Rev. Neurosci
, vol.4
, pp. 49-60
-
-
Soto, C.1
-
43
-
-
0034657130
-
Evidence for seeding of p-amyloid by intracerebral infusion of Alzheimer brain extracts in p-amyloid precursor protein-transgenic mice
-
Kane, M.D. et al. Evidence for seeding of p-amyloid by intracerebral infusion of Alzheimer brain extracts in p-amyloid precursor protein-transgenic mice. J. Neurosci. 20, 3606-3611 (2000).
-
(2000)
J. Neurosci
, vol.20
, pp. 3606-3611
-
-
Kane, M.D.1
-
44
-
-
0037076355
-
Transmissibility of systemic amyloidosis by a prion-like mechanism
-
Lundmark, K. et al. Transmissibility of systemic amyloidosis by a prion-like mechanism. Proc. Natl. Acad. Sci. USA 99, 6979-6984 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 6979-6984
-
-
Lundmark, K.1
-
45
-
-
0030006902
-
Two mutant prion proteins expressed in cultured cells acquire biochemical properties reminiscent of the scrapie isoform
-
Lehmann, S. & Harris, D.A. Two mutant prion proteins expressed in cultured cells acquire biochemical properties reminiscent of the scrapie isoform. Proc. Natl. Acad. Sci. USA 93, 5610-5614 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5610-5614
-
-
Lehmann, S.1
Harris, D.A.2
-
46
-
-
0032427904
-
Neurological illness in trans- genic mice expressing a prion protein with an insertional mutation
-
Chiesa, R., Piccardo, P., Ghetti, B. & Harris, D.A. Neurological illness in trans- genic mice expressing a prion protein with an insertional mutation. Neuron 21, 1339-1351 (1998).
-
(1998)
Neuron
, vol.21
, pp. 1339-1351
-
-
Chiesa, R.1
Piccardo, P.2
Ghetti, B.3
Harris, D.A.4
-
47
-
-
0033583190
-
Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations
-
Jackson, G.S. et al. Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations. Science 283, 1935-1937 (1999).
-
(1999)
Science
, vol.283
, pp. 1935-1937
-
-
Jackson, G.S.1
-
48
-
-
0032892306
-
Protease-resistant prion protein produced in vitro lacks detectable infectivity
-
Hill, A.F., Antoniou, M. & Collinge, J. Protease-resistant prion protein produced in vitro lacks detectable infectivity. J. Gen. Virol. 80, 11-14 (1999).
-
(1999)
J. Gen. Virol
, vol.80
, pp. 11-14
-
-
Hill, A.F.1
Antoniou, M.2
Collinge, J.3
-
49
-
-
0038447100
-
Evaluation of quinacrine treatment for prion diseases
-
Barret, A. et al. Evaluation of quinacrine treatment for prion diseases. J. Virol. 77, 8462-8469 (2003).
-
(2003)
J. Virol
, vol.77
, pp. 8462-8469
-
-
Barret, A.1
-
50
-
-
0028308104
-
[URE3] as an altered URE2 protein: Evidence for a prion analog in Saccharomyces cerevisiae
-
Wickner, R.B. [URE3] as an altered URE2 protein: Evidence for a prion analog in Saccharomyces cerevisiae. Science 264, 566-569 (1994).
-
(1994)
Science
, vol.264
, pp. 566-569
-
-
Wickner, R.B.1
-
51
-
-
0036403732
-
Prions as protein-based genetic elements
-
Uptain, S.M. & Lindquist, S. Prions as protein-based genetic elements. Annu. Rev. Microbiol. 56, 703-741 (2002).
-
(2002)
Annu. Rev. Microbiol
, vol.56
, pp. 703-741
-
-
Uptain, S.M.1
Lindquist, S.2
-
52
-
-
0034725747
-
Evidence for the prion hypothesis: Induction of the yeast [PSI+] factor by in vitro-converted Sup35 protein
-
Sparrer, H.E., Santoso, A., Szoka, F.C., Jr & Weissman, J.S. Evidence for the prion hypothesis: Induction of the yeast [PSI+] factor by in vitro-converted Sup35 protein. Science 289, 595-599 (2000).
-
(2000)
Science
, vol.289
, pp. 595-599
-
-
Sparrer, H.E.1
Santoso, A.2
Szoka, F.C.3
Weissman, J.S.4
-
53
-
-
0037188506
-
Amyloid aggregates of the HET-s prion protein are infectious
-
Maddelein, M.L., Dos, R.S., Duvezin-Caubet, S., Coulary-Salin, B. & Saupe, S.J. Amyloid aggregates of the HET-s prion protein are infectious. Proc. Natl. Acad. Sci. USA 99, 7402-7407 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 7402-7407
-
-
Maddelein, M.L.1
Dos, R.S.2
Duvezin-Caubet, S.3
Coulary-Salin, B.4
Saupe, S.J.5
-
54
-
-
1642617641
-
Protein-only transmission of three yeast prion strains
-
King, C.Y. & Diaz-Avalos, R. Protein-only transmission of three yeast prion strains. Nature 428, 319-323 (2004).
-
(2004)
Nature
, vol.428
, pp. 319-323
-
-
King, C.Y.1
Diaz-Avalos, R.2
-
55
-
-
1642633056
-
Conformational variations in an infectious protein determine prion strain differences
-
Tanaka, M., Chien, P., Naber, N., Cooke, R. & Weissman, J.S. Conformational variations in an infectious protein determine prion strain differences. Nature 428, 323-328 (2004).
-
(2004)
Nature
, vol.428
, pp. 323-328
-
-
Tanaka, M.1
Chien, P.2
Naber, N.3
Cooke, R.4
Weissman, J.S.5
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