Three consecutive arginines are important for the mycobacterial peptide deformylase enzyme activity

Journal of Biological Chemistry

Volumn 283, Issue 35, 2008, Pages 23754-23764

  Saxena, Rahul ^a,b   Kanudia, Pavitra ^a   Datt, Manish ^a   Dar, Haider Hussain ^a   Karthikeyan, Subramanian ^a   Singh, Balvinder ^a   Chakraborti, Pradip K ^a  

^a INSTITUTE OF MICROBIAL TECHNOLOGY   (India)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; DICHROISM; DYNAMICS; ENZYME ACTIVITY; ENZYMES; MOLECULAR DYNAMICS; OPTICAL PROPERTIES; ORGANIC ACIDS; POLYPEPTIDES; QUANTUM CHEMISTRY; SYNTHESIS (CHEMICAL);

ACTIVE SITES; AMINO ACID SEQUENCES; ANTI SENSES; ARGININE RESIDUES; CIRCULAR DICHROISMS; EUBACTERIA; FORMYL GROUPS; FUTURE DESIGNS; GENES ENCODING; M. TUBERCULOSES; MOLECULAR DYNAMICS SIMULATIONS; MYCOBACTERIAL; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; PEPTIDE DEFORMYLASE; PROTEIN SYNTHESES; STRUCTURAL ALTERATIONS; SUBSTRATE BINDINGS; TRIPLE MUTANTS;

AMINO ACIDS;

ANTISENSE OLIGODEOXYNUCLEOTIDE; ARGININE DERIVATIVE; ARYLFORMAMIDASE; BACTERIAL ENZYME; BACTERIAL PROTEIN; AMIDASE; ANTISENSE OLIGONUCLEOTIDE; ARGININE; PEPTIDE DEFORMYLASE;

AMINO ACID SEQUENCE; ARTICLE; BACTERIUM CULTURE; CIRCULAR DICHROISM; CONTROLLED STUDY; ENZYME ACTIVITY; MYCOBACTERIUM; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; AMINO ACID SUBSTITUTION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DRUG ANTAGONISM; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MISSENSE MUTATION; PHYSIOLOGY; PROTEIN PROCESSING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY;

BACTERIA (MICROORGANISMS); CORYNEBACTERINEAE; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS;

AMIDOHYDROLASES; AMINO ACID SUBSTITUTION; ARGININE; BINDING SITES; CIRCULAR DICHROISM; COMPUTER SIMULATION; MODELS, MOLECULAR; MUTATION, MISSENSE; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; OLIGONUCLEOTIDES, ANTISENSE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 53049090380     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M709672200     Document Type: Article

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