DNA damage and homologous recombination signaling induced by thymidylate deprivation

Biochemical Pharmacology

Volumn 76, Issue 8, 2008, Pages 987-996

  Yang, Zhengguan ^a   Waldman, Alan S ^a   Wyatt, Michael D ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Antifolates; Damage foci; Homologous recombination; RAD51; Replication protein A; Thymidylate deprivation

Indexed keywords

CHECKPOINT KINASE 1; DEOXYURIDINE TRIPHOSPHATE DERIVATIVE; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; DNA; HISTONE H2AX; NIBRIN; RAD51 PROTEIN; RALTITREXED; REPLICATION FACTOR A; REPLICATION PROTEIN A2; SMALL INTERFERING RNA; THYMIDINE PHOSPHATE; THYMIDYLATE SYNTHASE; UNCLASSIFIED DRUG; URACIL;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL STRAIN HT29; DNA DAMAGE; DNA REPLICATION; DNA STRAND BREAKAGE; ENZYME INHIBITION; EXCISION REPAIR; HELA CELL; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; IC 50; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

CELL LINE, TUMOR; CELL SURVIVAL; COLONIC NEOPLASMS; DNA DAMAGE; DNA, NEOPLASM; FLOW CYTOMETRY; FOLIC ACID; FOLIC ACID ANTAGONISTS; HELA CELLS; HUMANS; NUCLEOTIDES; PHOSPHORYLATION; QUINAZOLINES; RAD51 RECOMBINASE; RECOMBINATION, GENETIC; REPLICATION PROTEIN A; THIOPHENES; THYMIDINE MONOPHOSPHATE; THYMIDYLATE SYNTHASE;

EID: 52949117694     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.08.010     Document Type: Article

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