Computational and theoretical methods to explore the relation between enzyme dynamics and catalysis

Chemical Reviews

Volumn 106, Issue 8, 2006, Pages 3170-3187

  Antoniou, Dimitri ^a   Basner, Jodi ^a,b   Núñez, Sara ^a,c   Schwartz, Steven D ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b Bldg 142   (United States)

^c Solvay Pharmaceuticals Inc   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; COMPUTATIONAL METHODS; ELECTRON TUNNELING; QUANTUM THEORY; THERMODYNAMICS; VIBRATIONS (MECHANICAL);

CATALYTIC MECHANISM; DIHYDROFOLATE REDUCTASE (DHFR); ENZYME DYNAMICS; THERMODYNAMIC CYCLES;

ENZYMES;

LACTATE DEHYDROGENASE; PURINE NUCLEOSIDE PHOSPHORYLASE;

CATALYSIS; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; CONFORMATION; HUMAN; KINETICS; QUANTUM THEORY; REVIEW;

CATALYSIS; COMPUTER SIMULATION; HUMANS; KINETICS; L-LACTATE DEHYDROGENASE; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PURINE-NUCLEOSIDE PHOSPHORYLASE; QUANTUM THEORY;

EID: 33748614305     PISSN: 00092665     EISSN: None     Source Type: Journal    
DOI: 10.1021/cr0503052     Document Type: Review

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