A monoclonal antibody induces opening of a coiled coil. Global protection of amide protons from H/D exchange decreases by up to 1000-fold in antibody-bound triple-stranded coiled coil

European Journal of Biochemistry

Volumn 249, Issue 1, 1997, Pages 325-329

  Dürr, Eberhard ^a   Bosshard, Hans R ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Coiled coil; Conformational change; Electrospray ionization MS; H D exchange of amide protons; Monoclonal antibody

Indexed keywords

AMINO ACID SEQUENCE; ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CONFORMATIONAL TRANSITION; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN STRUCTURE; THERMODYNAMICS;

EID: 0030810528     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1997.t01-1-00325.x     Document Type: Article

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