Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site

Journal of Molecular Biology

Volumn 316, Issue 2, 2002, Pages 257-264

  Dunten, Pete ^a   Belunis, Charles ^a   Crowther, Robert ^a   Hollfelder, Kurt ^a   Kammlott, Ursula ^a   Levin, Wayne ^a   Michel, Hanspeter ^a   Ramsey, Gwendolyn B ^a   Swain, Amy ^a   Weber, David ^a   Wertheimer, Stanley J ^a  

^a HOFFMANN LA ROCHE INC   (United States)

Author keywords

Diabetes; Gluconeogenesis; Phosphoenolpyruvate carboxykinase; X ray structure

Indexed keywords

CITRIC ACID; GLUCOSE; GUANINE; GUANOSINE TRIPHOSPHATE; LACTIC ACID; PHENYLALANINE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP);

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CITRIC ACID CYCLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOSOL; ENZYME ANALYSIS; ENZYME BINDING; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; GLUCONEOGENESIS; GLUCOSE METABOLISM; HUMAN; HYPERGLYCEMIA; NON INSULIN DEPENDENT DIABETES MELLITUS; PRECURSOR; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION;

EID: 18444386228     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.5364     Document Type: Article

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