Dineopentyl phosphate hydrolysis: Evidence for stepwise water attack

Journal of Organic Chemistry

Volumn 73, Issue 18, 2008, Pages 6960-6969

  Kamerlin, Shina C L ^a   Williams, Nicholas H ^b   Warshel, Arieh ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ENGINEERING; BIOCHEMISTRY; CATALYSTS; ENZYMES; ESTERIFICATION; ESTERS; FOOD ADDITIVES; FREE ENERGY; HYDROCARBONS; HYDROLYSIS; ORGANIC COMPOUNDS; PROTEINS; PROTON TRANSFER; PROTONS; RATE CONSTANTS;

ENERGY PRODUCTIONS; EQUIVALENT MECHANISMS; EXPERIMENTAL DATA; EXPERIMENTAL METHODS; FREE-ENERGY SURFACES; INTENSIVE RESEARCH; MECHANISM OF ACTIONS; METHYL GROUPS; NUCLEOPHILIC ATTACKS; PHOSPHATE DIESTERS; PHOSPHATE ESTER HYDROLYSIS; PHOSPHORANE; PROTEIN FUNCTIONS; REACTION PATHWAYS; SIMPLE REACTION; TRIESTERS;

MECHANISMS;

DINEOPENTYL PHOSPHATE; GUANOSINE TRIPHOSPHATE; ORGANOPHOSPHATE; PHOSPHORANE DERIVATIVE; RAS PROTEIN; UNCLASSIFIED DRUG; WATER;

AB INITIO CALCULATION; ARTICLE; CATALYSIS; CHEMICAL REACTION; DENSITY FUNCTIONAL THEORY; ENERGY; ENZYME REGULATION; ENZYME SUBSTRATE; HYDROLYSIS; PH; REACTION ANALYSIS;

COMPUTER SIMULATION; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; HYDROXIDES; KINETICS; MODELS, CHEMICAL; MOLECULAR STRUCTURE; ORGANOPHOSPHORUS COMPOUNDS; PROTONS; WATER;

EID: 52449134610     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo801207q     Document Type: Article

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