What are the roles of substrate-assisted catalysis and proximity effects in peptide bond formation by the ribosome?

Biochemistry

Volumn 44, Issue 34, 2005, Pages 11307-11314

  Sharma, Pankaz K ^a   Xiang, Yun ^a   Kato, Mitsunori ^a   Warshel, Arieh ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CHEMICAL BONDS; COMPUTER SIMULATION; ELECTROSTATICS; ENTROPY; ENZYMES; REACTION KINETICS; SUBSTRATES;

BOND FORMATION; CATALYTIC POWER; PROXIMITY EFFECTS; REFERENCE SOLUTION;

RNA;

PEPTIDYLTRANSFERASE; PROTEIN; RNA; WATER;

ACCELERATION; ARTICLE; CALCULATION; CATALYSIS; CATALYST; CHEMICAL BOND; COMPUTER SIMULATION; ENERGY TRANSFER; ENTROPY; ENZYME ACTIVITY; PEPTIDE BOND; PRIORITY JOURNAL; REACTION ANALYSIS; REACTION TIME; RIBOSOME; SOLVATION;

BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; EVOLUTION, MOLECULAR; MODELS, MOLECULAR; MODELS, THEORETICAL; PEPTIDES; PEPTIDYL TRANSFERASES; PROTEIN CONFORMATION; RIBOSOMES; RNA;

EID: 23944472625     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0509806     Document Type: Article

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