Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21(ras)

Biochemistry

Volumn 35, Issue 45, 1996, Pages 14225-14231

  Schweins, T ^a,b   Geyer, M ^c   Kalbitzer, H R ^c   Wittinghofer, A ^b   Warshel, A ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^c MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; PROTEIN P21;

ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME SUBSTRATE COMPLEX; GENE MUTATION; HUMAN; HYDROLYSIS; LINEAR ENERGY TRANSFER; ONCOGENE RAS; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

BINDING SITES; ENZYME ACTIVATION; GTP PHOSPHOHYDROLASES; GTPASE-ACTIVATING PROTEINS; GUANOSINE TRIPHOSPHATE; HUMANS; KINETICS; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEINS; PROTO-ONCOGENE PROTEINS P21(RAS); RAS GTPASE-ACTIVATING PROTEINS; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 0029825324     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi961118o     Document Type: Article

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