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Volumn 185, Issue PART2, 2008, Pages 341-359

Molecular imaging-guided gene therapy of gliomas

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; BRAIN TUMOR; COMPUTER ASSISTED DIAGNOSIS; DIAGNOSTIC IMAGING; GENE EXPRESSION REGULATION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETICS; GLIOMA; HUMAN; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; POSITRON EMISSION TOMOGRAPHY; REVIEW; TREATMENT OUTCOME;

EID: 52049123085     PISSN: 01712004     EISSN: 18650325     Source Type: Book Series    
DOI: 10.1007/978-3-540-77496-9_15     Document Type: Article
Times cited : (6)

References (109)
  • 1
    • 0032893756 scopus 로고    scopus 로고
    • Malignant transformation alters membrane choline phospholipid metabolism of human mammary epithelial cells
    • Aboagye EO, Bhujwalla ZM (1999) Malignant transformation alters membrane choline phospholipid metabolism of human mammary epithelial cells. Cancer Res 59:80-84
    • (1999) Cancer Res , vol.59 , pp. 80-84
    • Aboagye, E.O.1    Bhujwalla, Z.M.2
  • 2
    • 0344200002 scopus 로고    scopus 로고
    • Multimodal cancer treatment mediated by replicating oncolytic virus that delivers the oxazaphosphorine/rat cytochrome P450 2B1 and ganciclovir/herpes simplex virus thymidine kinase gene therapies
    • Aghi M, Chou TC, Suling K, Breakefield XO, Chiocca A (1999) Multimodal cancer treatment mediated by replicating oncolytic virus that delivers the oxazaphosphorine/rat cytochrome P450 2B1 and ganciclovir/herpes simplex virus thymidine kinase gene therapies. Cancer Res 59:3861-3865
    • (1999) Cancer Res , vol.59 , pp. 3861-3865
    • Aghi, M.1    Chou, T.C.2    Suling, K.3    Breakefield, X.O.4    Chiocca, A.5
  • 3
    • 4644294588 scopus 로고    scopus 로고
    • Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model
    • Alauddin MM, Shahinian A, Gordon EM, Conti PS (2004a) Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model. Mol Imaging 3:76-84
    • (2004) Mol Imaging , vol.3 , pp. 76-84
    • Alauddin, M.M.1    Shahinian, A.2    Gordon, E.M.3    Conti, P.S.4
  • 4
    • 16644366895 scopus 로고    scopus 로고
    • Synthesis and evaluation of 2-deoxy-2-18F-fluoro-5-fluoro-1-beta-D- arabinofuranosyluracil as a potential PET imaging agent for suicide gene expression
    • Alauddin MM, Shahinian A, Park R, Tohme M, Fissekis JD, Conti PS (2004b) Synthesis and evaluation of 2-deoxy-2-18F-fluoro-5-fluoro-1-beta-D- arabinofuranosyluracil as a potential PET imaging agent for suicide gene expression. J Nucl Med 45:2063-2069
    • (2004) J Nucl Med , vol.45 , pp. 2063-2069
    • Alauddin, M.M.1    Shahinian, A.2    Park, R.3    Tohme, M.4    Fissekis, J.D.5    Conti, P.S.6
  • 5
    • 0031016159 scopus 로고    scopus 로고
    • 18-Fluorodeoxyglucose uptake and survival of patients with suspected recurrent malignant glioma
    • Barker FG, Chang SM, Valk PE, Pounds TR, Prados MD (1997) 18-Fluorodeoxyglucose uptake and survival of patients with suspected recurrent malignant glioma. Cancer 79:115-126
    • (1997) Cancer , vol.79 , pp. 115-126
    • Barker, F.G.1    Chang, S.M.2    Valk, P.E.3    Pounds, T.R.4    Prados, M.D.5
  • 6
    • 0012473447 scopus 로고    scopus 로고
    • Molecular-genetic imaging: A nuclear medicine-based perspective
    • Blasberg RG, Gelovani J (2002) Molecular-genetic imaging: a nuclear medicine-based perspective. Mol Imaging 1:280-300
    • (2002) Mol Imaging , vol.1 , pp. 280-300
    • Blasberg, R.G.1    Gelovani, J.2
  • 7
    • 0033953623 scopus 로고    scopus 로고
    • Early evaluation of tumour metabolic response using [18F] fluorodeoxyglucose and positron emission tomography: A pilot study following the phase II chemotherapy schedule for temozolomide in recurrent high-grade gliomas
    • Brock CS, Young H, O'Reilly SM et al (2000) Early evaluation of tumour metabolic response using [18F]fluorodeoxyglucose and positron emission tomography: a pilot study following the phase II chemotherapy schedule for temozolomide in recurrent high-grade gliomas. Br J Cancer 82:608-615
    • (2000) Br J Cancer , vol.82 , pp. 608-615
    • Brock, C.S.1    Young, H.2    O'reilly, S.M.3
  • 8
    • 0035919216 scopus 로고    scopus 로고
    • The sensitivity and specificity of FDG PET in distinguishing recurrent brain tumor from radionecrosis in patients treated with stereotactic radiosurgery
    • Chao ST, Suh JH, Raja S, Lee SY, Barnett G (2001) The sensitivity and specificity of FDG PET in distinguishing recurrent brain tumor from radionecrosis in patients treated with stereotactic radiosurgery. Int J Cancer 96:191-197
    • (2001) Int J Cancer , vol.96 , pp. 191-197
    • Chao, S.T.1    Suh, J.H.2    Raja, S.3    Lee, S.Y.4    Barnett, G.5
  • 9
    • 0034694661 scopus 로고    scopus 로고
    • Diffusion magnetic resonance imaging: An early surrogate marker of therapeutic efficacy in brain tumors
    • Chenevert TL, Stegman LD, Taylor JM et al (2000) Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors. J Natl Cancer Inst 92: 2029-2036
    • (2000) J Natl Cancer Inst , vol.92 , pp. 2029-2036
    • Chenevert, T.L.1    Stegman, L.D.2    Taylor, J.M.3
  • 10
    • 22444450186 scopus 로고    scopus 로고
    • SPECT imaging of herpes simplex virus type1 thymidine kinase gene expression by [(123)I]FIAU(1)
    • Choi SR, Zhuang ZP, Chacko AM et al (2005) SPECT imaging of herpes simplex virus type1 thymidine kinase gene expression by [(123)I]FIAU(1). Acad Radiol 12:798-805
    • (2005) Acad Radiol , vol.12 , pp. 798-805
    • Choi, S.R.1    Zhuang, Z.P.2    Chacko, A.M.3
  • 11
    • 0036167148 scopus 로고    scopus 로고
    • Usefulness of 11C-methionine PET in the evaluation of brain lesions that are hypo-or isometabolic on 18F-FDG PET
    • Chung JK, Kim K, Kim SK et al (2002) Usefulness of 11C-methionine PET in the evaluation of brain lesions that are hypo-or isometabolic on 18F-FDG PET. Eur J Nucl Med Mol Imaging 29:176-182
    • (2002) Eur J Nucl Med Mol Imaging , vol.29 , pp. 176-182
    • Chung, J.K.1    Kim, K.2    Kim, S.K.3
  • 13
    • 0034804988 scopus 로고    scopus 로고
    • Correlation between magnetic resonance spectroscopy imaging and image-guided biopsies: Semiquantitative and qualitative histopathological analyses of patients with untreated glioma
    • Croteau D, Scarpace L, Hearshen D et al (2001) Correlation between magnetic resonance spectroscopy imaging and image-guided biopsies: semiquantitative and qualitative histopathological analyses of patients with untreated glioma. Neurosurgery 49:823-829
    • (2001) Neurosurgery , vol.49 , pp. 823-829
    • Croteau, D.1    Scarpace, L.2    Hearshen, D.3
  • 14
    • 0026772206 scopus 로고
    • In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
    • Culver KW, Ram Z, Wallbridge S, Ishii H, Oldfield EH, Blaese RM (1992) In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 256:1550-1552
    • (1992) Science , vol.256 , pp. 1550-1552
    • Culver, K.W.1    Ram, Z.2    Wallbridge, S.3    Ishii, H.4    Oldfield, E.H.5    Blaese, R.M.6
  • 15
    • 0036389499 scopus 로고    scopus 로고
    • Positron emission tomography: Measurement of transgene expression
    • de Vries EF, VaalburgW(2002) Positron emission tomography: measurement of transgene expression. Methods 27:234-241
    • (2002) Methods , vol.27 , pp. 234-241
    • De Vries, E.F.1    Vaalburg, W.2
  • 17
    • 0029770438 scopus 로고    scopus 로고
    • Prognostic value positron emission tomography with [18F]fluoro-2-deoxy-D- glucose in the low-grade glioma
    • De Witte O, Levivier M, Violon P et al (1996) Prognostic value positron emission tomography with [18F]fluoro-2-deoxy-D-glucose in the low-grade glioma. Neurosurgery 39:470-476
    • (1996) Neurosurgery , vol.39 , pp. 470-476
    • De Witte, O.1    Levivier, M.2    Violon, P.3
  • 18
    • 0034756420 scopus 로고    scopus 로고
    • Positron emission tomography with injection of methionine as a prognostic factor in glioma
    • De Witte O, Goldberg I, Wikler D et al (2001) Positron emission tomography with injection of methionine as a prognostic factor in glioma. J Neurosurg 95:746-750
    • (2001) J Neurosurg , vol.95 , pp. 746-750
    • De Witte, O.1    Goldberg, I.2    Wikler, D.3
  • 19
    • 1642512319 scopus 로고    scopus 로고
    • Non-invasive in vivo imaging with radiolabelled FIAU for monitoring cancer gene therapy using herpes simplex virus type 1 thymidine kinase and ganciclovir
    • Deng WP, Yang WK, Lai WF et al (2004) Non-invasive in vivo imaging with radiolabelled FIAU for monitoring cancer gene therapy using herpes simplex virus type 1 thymidine kinase and ganciclovir. Eur J Nucl Med Mol Imaging 31:99-109
    • (2004) Eur J Nucl Med Mol Imaging , vol.31 , pp. 99-109
    • Deng, W.P.1    Yang, W.K.2    Lai, W.F.3
  • 20
    • 0029113635 scopus 로고
    • Decreased cerebral glucose metabolism in patients with brain tumors: An effect of corticosteroids
    • Fulham MJ, Brunetti A, Aloj L, Raman R, Dwyer AJ, Di Chiro G (1995) Decreased cerebral glucose metabolism in patients with brain tumors: an effect of corticosteroids. J Neurosurg 83:657-664
    • (1995) J Neurosurg , vol.83 , pp. 657-664
    • Fulham, M.J.1    Brunetti, A.2    Aloj, L.3    Raman, R.4    Dwyer, A.J.5    Di Chiro, G.6
  • 21
    • 0042386691 scopus 로고    scopus 로고
    • Combretastatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic magnetic resonance imaging
    • Galbraith SM, Maxwell RJ, Lodge MA et al (2003) Combretastatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic magnetic resonance imaging. J Clin Oncol 21:2831-2842
    • (2003) J Clin Oncol , vol.21 , pp. 2831-2842
    • Galbraith, S.M.1    Maxwell, R.J.2    Ma, L.3
  • 22
    • 33646395417 scopus 로고    scopus 로고
    • Use of (11)C-methionine PET to monitor the effects of temozolomide chemotherapy in malignant gliomas
    • Galldiks N, Kracht LW, Burghaus L et al (2006) Use of (11)C-methionine PET to monitor the effects of temozolomide chemotherapy in malignant gliomas. Eur J Nucl Med Mol Imaging 33:516-524
    • (2006) Eur J Nucl Med Mol Imaging , vol.33 , pp. 516-524
    • Galldiks, N.1    Kracht, L.W.2    Burghaus, L.3
  • 23
    • 0031742514 scopus 로고    scopus 로고
    • Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir
    • Gambhir SS, Barrio JR, Wu L et al (1998) Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir. J Nucl Med 39:2003-2011
    • (1998) J Nucl Med , vol.39 , pp. 2003-2011
    • Gambhir, S.S.1    Barrio, J.R.2    Wu, L.3
  • 24
    • 0034048929 scopus 로고    scopus 로고
    • Imaging transgene expression with radionuclide imaging technologies
    • Gambhir SS, Herschman HR, Cherry SR et al (2000) Imaging transgene expression with radionuclide imaging technologies. Neoplasia 2:118-138
    • (2000) Neoplasia , vol.2 , pp. 118-138
    • Gambhir, S.S.1    Herschman, H.R.2    Cherry, S.R.3
  • 25
    • 0025794065 scopus 로고
    • Identification of early recurrence of primary central nervous system tumors by [18F]fluorodeoxyglucose positron emission tomography
    • Glantz MJ, Hoffman JM, Coleman RE et al (1991) Identification of early recurrence of primary central nervous system tumors by [18F]fluorodeoxyglucose positron emission tomography. Ann Neurol 29:347-355
    • (1991) Ann Neurol , vol.29 , pp. 347-355
    • Glantz, M.J.1    Hoffman, J.M.2    Coleman, R.E.3
  • 27
    • 0036189478 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced magnetic resonance imaging as a surrogate marker of tumor response to anti-angiogenic therapy in a xenograft model of glioblastoma multiforme
    • Gossmann A, Helbich TH, Kuriyama N et al (2002) Dynamic contrast-enhanced magnetic resonance imaging as a surrogate marker of tumor response to anti-angiogenic therapy in a xenograft model of glioblastoma multiforme. J Magn Reson Imaging 15:233-240
    • (2002) J Magn Reson Imaging , vol.15 , pp. 233-240
    • Gossmann, A.1    Helbich, T.H.2    Kuriyama, N.3
  • 28
    • 6944256513 scopus 로고    scopus 로고
    • A tracer kinetic model for 18F-FHBG for quantitating herpes simplex virus type 1 thymidine kinase reporter gene expression in living animals using PET
    • Green LA, Nguyen K, Berenji B et al (2004) A tracer kinetic model for 18F-FHBG for quantitating herpes simplex virus type 1 thymidine kinase reporter gene expression in living animals using PET. J Nucl Med 45:1560-1570
    • (2004) J Nucl Med , vol.45 , pp. 1560-1570
    • Green, L.A.1    Nguyen, K.2    Berenji, B.3
  • 29
    • 0002016402 scopus 로고    scopus 로고
    • Imaging expression of cytosine deaminaseherpes virus thymidine kinase fusion gene (CD/TK) expression with [124I]FIAU and PET
    • Hackman T, Doubrovin M, Balatoni J et al (2002) Imaging expression of cytosine deaminaseherpes virus thymidine kinase fusion gene (CD/TK) expression with [124I]FIAU and PET. Mol Imaging 1:36-42
    • (2002) Mol Imaging , vol.1 , pp. 36-42
    • Hackman, T.1    Doubrovin, M.2    Balatoni, J.3
  • 30
    • 0032590214 scopus 로고    scopus 로고
    • 1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: Implications for the in vivo detection of apoptosis
    • Hakumaki JM, Poptani H, Sandmair AM, Yla-Herttuala S, Kauppinen RA (1999) 1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: implications for the in vivo detection of apoptosis. Nat Med 5:1323-1327
    • (1999) Nat Med , vol.5 , pp. 1323-1327
    • Hakumaki, J.M.1    Poptani, H.2    Sandmair, A.M.3    Yla-Herttuala, S.4    Kauppinen, R.A.5
  • 31
    • 0034095219 scopus 로고    scopus 로고
    • Thymidine kinase activation of ganciclovir in recurrent malignant gliomas: A gene-marking and neuropathological study
    • Harsh GR, Deisboeck TS, Louis DN et al (2000) Thymidine kinase activation of ganciclovir in recurrent malignant gliomas: a gene-marking and neuropathological study. J Neurosurg 92: 804-811
    • (2000) J Neurosurg , vol.92 , pp. 804-811
    • Harsh, G.R.1    Deisboeck, T.S.2    Louis, D.N.3
  • 32
    • 1242271955 scopus 로고    scopus 로고
    • Diffusion-weighted imaging in the follow-up of treated high-grade gliomas: Tumor recurrence versus radiation injury
    • Hein PA, Eskey CJ, Dunn JF, Hug EB (2004) Diffusion-weighted imaging in the follow-up of treated high-grade gliomas: tumor recurrence versus radiation injury. AJNR Am J Neuroradiol 25:201-209
    • (2004) AJNR Am J Neuroradiol , vol.25 , pp. 201-209
    • Hein, P.A.1    Eskey, C.J.2    Dunn, J.F.3    Hug, E.B.4
  • 33
    • 0021140061 scopus 로고
    • Regional kinetic constants and cerebral metabolic rate for glucose in normal human volunteers determined by dynamic positron emission tomography of [18F]-2-fluoro-2-deoxy-D-glucose
    • Heiss WD, Pawlik G, Herholz K, Wagner R, Goldner H, Wienhard K (1984) Regional kinetic constants and cerebral metabolic rate for glucose in normal human volunteers determined by dynamic positron emission tomography of [18F]-2-fluoro-2-deoxy-D-glucose. J Cereb Blood Flow Metab 4:212-223
    • (1984) J Cereb Blood Flow Metab , vol.4 , pp. 212-223
    • Heiss, W.D.1    Pawlik, G.2    Herholz, K.3    Wagner, R.4    Goldner, H.5    Wienhard, K.6
  • 34
    • 0025271517 scopus 로고
    • Positron emission tomography of fluorine-18-deoxyglucose and image-guided phosphorus-31 magnetic resonance spectroscopy in brain tumors
    • Heiss WD, Heindel W, Herholz K et al (1990) Positron emission tomography of fluorine-18-deoxyglucose and image-guided phosphorus-31 magnetic resonance spectroscopy in brain tumors. J Nucl Med 31:302-310
    • (1990) J Nucl Med , vol.31 , pp. 302-310
    • Heiss, W.D.1    Heindel, W.2    Herholz, K.3
  • 36
    • 0026544671 scopus 로고
    • In vivo imaging of glucose consumption and lactate concentration in human gliomas
    • Herholz K, HeindelW, Luyten PR et al (1992) In vivo imaging of glucose consumption and lactate concentration in human gliomas. Ann Neurol 31:319-327
    • (1992) Ann Neurol , vol.31 , pp. 319-327
    • Herholz, K.1    Heindel, W.2    Luyten, P.R.3
  • 37
    • 0027527761 scopus 로고
    • Correlation of glucose consumption and tumor cell density in astrocytomas
    • Herholz K, Pietrzyk U, Voges J et al (1993) Correlation of glucose consumption and tumor cell density in astrocytomas. A stereotactic PET study. J Neurosurg 79:853-858
    • (1993) A Stereotactic PET Study. J Neurosurg , vol.79 , pp. 853-858
    • Herholz, K.1    Pietrzyk, U.2    Voges, J.3
  • 38
    • 0031596996 scopus 로고    scopus 로고
    • 11C-methionine PET for differential diagnosis of lowgrade gliomas
    • Herholz K, Holzer T, Bauer B et al (1998) 11C-methionine PET for differential diagnosis of lowgrade gliomas. Neurology 50:1316-1322
    • (1998) Neurology , vol.50 , pp. 1316-1322
    • Herholz, K.1    Holzer, T.2    Bauer, B.3
  • 39
    • 0038798593 scopus 로고    scopus 로고
    • Monitoring the effect of chemotherapy in a mixed glioma by C-11-methionine PET
    • Herholz K, Kracht LW, HeissWD(2003) Monitoring the effect of chemotherapy in a mixed glioma by C-11-methionine PET. J Neuroimaging 13:269-271
    • (2003) J Neuroimaging , vol.13 , pp. 269-271
    • Herholz, K.1    Kracht, L.W.2    Heiss, W.D.3
  • 40
    • 0036792374 scopus 로고    scopus 로고
    • Increased choline levels coincide with enhanced proliferative activity of human neuroepithelial brain tumors
    • Herminghaus S, Pilatus U, Moller-Hartmann W et al (2002) Increased choline levels coincide with enhanced proliferative activity of human neuroepithelial brain tumors. NMR Biomed 15: 385-392
    • (2002) NMR Biomed , vol.15 , pp. 385-392
    • Herminghaus, S.1    Pilatus, U.2    Moller-Hartmann, W.3
  • 41
    • 0033954691 scopus 로고    scopus 로고
    • Researchers and regulators reflect on first gene therapy death
    • Hollon T (2000) Researchers and regulators reflect on first gene therapy death. Nat Med 6:6
    • (2000) Nat Med , vol.6 , pp. 6
    • Hollon, T.1
  • 44
    • 0033139768 scopus 로고    scopus 로고
    • Functional coexpression of HSV-1 thymidine kinase and green fluorescent protein: Implications for noninvasive imaging of transgene expression
    • Jacobs AH, Dubrovin M, Hewett J et al (1999c) Functional coexpression of HSV-1 thymidine kinase and green fluorescent protein: implications for noninvasive imaging of transgene expression. Neoplasia 1:154-161
    • (1999) Neoplasia , vol.1 , pp. 154-161
    • Jacobs, A.H.1    Dubrovin, M.2    Hewett, J.3
  • 45
    • 0035448565 scopus 로고    scopus 로고
    • Positron-emission tomography of vector-mediated gene expression in gene therapy for gliomas
    • Jacobs AH, Voges J, Reszka R et al (2001) Positron-emission tomography of vector-mediated gene expression in gene therapy for gliomas. Lancet 358:727-729
    • (2001) Lancet , vol.358 , pp. 727-729
    • Jacobs, A.H.1    Voges, J.2    Reszka, R.3
  • 47
    • 0348134527 scopus 로고    scopus 로고
    • Imaging in gene therapy of patients with glioma
    • Jacobs AH, Voges J, Kracht LW et al (2003a) Imaging in gene therapy of patients with glioma. J Neurooncol 65:291-305
    • (2003) J Neurooncol , vol.65 , pp. 291-305
    • Jacobs, A.H.1    Voges, J.2    Kracht, L.W.3
  • 48
    • 0037429004 scopus 로고    scopus 로고
    • Improved herpes simplex virus type 1 amplicon vectors for proportional coexpression of positron emission tomography marker and therapeutic genes
    • Jacobs AH, Winkeler A, Hartung M et al (2003b) Improved herpes simplex virus type 1 amplicon vectors for proportional coexpression of positron emission tomography marker and therapeutic genes. Hum Gene Ther 14:277-297
    • (2003) Hum Gene Ther , vol.14 , pp. 277-297
    • Jacobs, A.H.1    Winkeler, A.2    Hartung, M.3
  • 50
    • 33644877069 scopus 로고    scopus 로고
    • 18F-fluoro-L-thymidine and 11Cmethylmethionine as markers of increased transport and proliferation in brain tumors
    • Jacobs AH, Thomas A, Kracht LW et al (2005b) 18F-fluoro-L-thymidine and 11Cmethylmethionine as markers of increased transport and proliferation in brain tumors. J Nucl Med 46:1948-1958
    • (2005) J Nucl Med , vol.46 , pp. 1948-1958
    • Jacobs, A.H.1    Thomas, A.2    Kracht, L.W.3
  • 51
    • 33847728953 scopus 로고    scopus 로고
    • Imaging-guided gene therapy of experimental gliomas
    • Jacobs AH, Rueger MA, Winkeler A et al (2007) Imaging-guided gene therapy of experimental gliomas. Cancer Res 67:1706-1715
    • (2007) Cancer Res , vol.67 , pp. 1706-1715
    • Jacobs, A.H.1    Rueger, M.A.2    Winkeler, A.3
  • 52
    • 33646787078 scopus 로고    scopus 로고
    • Comparison of [14C]FMAU, [3H]FEAU, [14C]FIAU, and [3H]PCV for monitoring reporter gene expression of wild type and mutant herpes simplex virus type 1 thymidine kinase in cell culture
    • Kang KW, Min JJ, Chen X, Gambhir SS (2005) Comparison of [14C]FMAU, [3H]FEAU, [14C]FIAU, and [3H]PCV for monitoring reporter gene expression of wild type and mutant herpes simplex virus type 1 thymidine kinase in cell culture. Mol Imaging Biol 7:296-303
    • (2005) Mol Imaging Biol , vol.7 , pp. 296-303
    • Kang, K.W.1    Min, J.J.2    Chen, X.3    Gambhir, S.S.4
  • 53
    • 0031968208 scopus 로고    scopus 로고
    • Preoperative evaluation of 54 gliomas by PET with fluorine-18- fluorodeoxyglucose and/or carbon-11-methionine
    • Kaschten B, Stevenaert A, Sadzot B et al (1998) Preoperative evaluation of 54 gliomas by PET with fluorine-18-fluorodeoxyglucose and/or carbon-11-methionine. J Nucl Med 39:778-785
    • (1998) J Nucl Med , vol.39 , pp. 778-785
    • Kaschten, B.1    Stevenaert, A.2    Sadzot, B.3
  • 54
    • 0026823461 scopus 로고
    • Differentiation of residual or recurrent tumors from post-treatment changes with F-18 FDG PET
    • Kim EE, Chung SK, Haynie TP et al (1992) Differentiation of residual or recurrent tumors from post-treatment changes with F-18 FDG PET. Radiographics 12:269-279
    • (1992) Radiographics , vol.12 , pp. 269-279
    • Kim, E.E.1    Chung, S.K.2    Haynie, T.P.3
  • 55
    • 4544316108 scopus 로고    scopus 로고
    • Multimodality imaging of lymphocytic migration using lentiviral-based transduction of a tri-fusion reporter gene
    • Kim YJ, Dubey P, Ray P, Gambhir SS, Witte ON (2004) Multimodality imaging of lymphocytic migration using lentiviral-based transduction of a tri-fusion reporter gene. Mol Imaging Biol 6:331-340
    • (2004) Mol Imaging Biol , vol.6 , pp. 331-340
    • Kim, Y.J.1    Dubey, P.2    Ray, P.3    Gambhir, S.S.4    Witte, O.N.5
  • 56
    • 2442767029 scopus 로고    scopus 로고
    • A phase I/II study of herpes simplex virus type 1 thymidine kinase suicide gene therapy for recurrent glioblastoma
    • Klatzmann D, Valery CA, Bensimon G et al (1998) A phase I/II study of herpes simplex virus type 1 thymidine kinase suicide gene therapy for recurrent glioblastoma. Study Group on Gene Therapy for Glioblastoma. Hum Gene Ther 9: 2595-2604
    • (1998) Study Group on Gene Therapy for Glioblastoma. Hum Gene Ther , vol.9 , pp. 2595-2604
    • Klatzmann, D.1    Valery, C.A.2    Bensimon, G.3
  • 58
    • 0033735455 scopus 로고    scopus 로고
    • Malignant gliomas: MR imaging spectrum of radiation therapy-and chemotherapy-induced necrosis of the brain after treatment
    • Kumar AJ, Leeds NE, Fuller GN et al (2000) Malignant gliomas: MR imaging spectrum of radiation therapy-and chemotherapy-induced necrosis of the brain after treatment. Radiology 217:377-384
    • (2000) Radiology , vol.217 , pp. 377-384
    • Kumar, A.J.1    Leeds, N.E.2    Fuller, G.N.3
  • 59
    • 18244425092 scopus 로고    scopus 로고
    • Transport mechanisms of 3-[123I]iodo-alpha-methyl-L-tyrosine in a human glioma cell line: Comparison with [3H]methyl]-L-methionine
    • Langen KJ, Muhlensiepen H, Holschbach M, Hautzel H, Jansen P, Coenen HH (2000) Transport mechanisms of 3-[123I]iodo-alpha-methyl-L-tyrosine in a human glioma cell line: comparison with [3H]methyl]-L-methionine. J Nucl Med 41:1250-1255
    • (2000) J Nucl Med , vol.41 , pp. 1250-1255
    • Langen, K.J.1    Muhlensiepen, H.2    Holschbach, M.3    Hautzel, H.4    Jansen, P.5    Coenen, H.H.6
  • 60
    • 26244436659 scopus 로고    scopus 로고
    • Metabolic differences between primary and recurrent human brain tumors: A 1H NMR spectroscopic investigation
    • Lehnhardt FG, Bock C, Rohn G, Ernestus RI, Hoehn M (2005) Metabolic differences between primary and recurrent human brain tumors: a 1H NMR spectroscopic investigation. NMR Biomed 18:371-382
    • (2005) NMR Biomed , vol.18 , pp. 371-382
    • Lehnhardt, F.G.1    Bock, C.2    Rohn, G.3    Ernestus, R.I.4    Hoehn, M.5
  • 61
    • 1442282498 scopus 로고    scopus 로고
    • Convection-enhanced delivery of paclitaxel for the treatment of recurrent malignant glioma: A phase I/II clinical study
    • Lidar Z, Mardor Y, Jonas T et al (2004) Convection-enhanced delivery of paclitaxel for the treatment of recurrent malignant glioma: a phase I/II clinical study. J Neurosurg 100:472-479
    • (2004) J Neurosurg , vol.100 , pp. 472-479
    • Lidar, Z.1    Mardor, Y.2    Jonas, T.3
  • 62
    • 0034491721 scopus 로고    scopus 로고
    • Pharmacokinetic analysis of glioma compartments with dynamic Gd-DTPA-enhanced magnetic resonance imaging
    • Ludemann L, Hamm B, Zimmer C (2000) Pharmacokinetic analysis of glioma compartments with dynamic Gd-DTPA-enhanced magnetic resonance imaging. Magn Reson Imaging 18: 1201-1214
    • (2000) Magn Reson Imaging , vol.18 , pp. 1201-1214
    • Ludemann, L.1    Hamm, B.2    Zimmer, C.3
  • 63
    • 6544233317 scopus 로고    scopus 로고
    • Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals
    • MacLaren DC, Gambhir SS, Satyamurthy N et al (1999) Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals. Gene Ther 6:785-791
    • (1999) Gene Ther , vol.6 , pp. 785-791
    • Maclaren, D.C.1    Gambhir, S.S.2    Satyamurthy, N.3
  • 64
    • 0034087594 scopus 로고    scopus 로고
    • Characterizing tumors using metabolic imaging: PET imaging of cellular proliferation and steroid receptors
    • Mankoff DA, Dehdashti F, Shields AF (2000) Characterizing tumors using metabolic imaging: PET imaging of cellular proliferation and steroid receptors. Neoplasia 2:71-88
    • (2000) Neoplasia , vol.2 , pp. 71-88
    • Mankoff, D.A.1    Dehdashti, F.2    Shields, A.F.3
  • 65
    • 0035394313 scopus 로고    scopus 로고
    • Monitoring response to convection-enhanced taxol delivery in brain tumor patients using diffusion-weighted magnetic resonance imaging
    • Mardor Y, Roth Y, Lidar Z et al (2001) Monitoring response to convection-enhanced taxol delivery in brain tumor patients using diffusion-weighted magnetic resonance imaging. Cancer Res 61:4971-4973
    • (2001) Cancer Res , vol.61 , pp. 4971-4973
    • Mardor, Y.1    Roth, Y.2    Lidar, Z.3
  • 66
    • 11144354376 scopus 로고    scopus 로고
    • Pretreatment prediction of brain tumors' response to radiation therapy using high b-value diffusion-weighted MRI
    • Mardor Y, Roth Y, Ochershvilli A et al (2004) Pretreatment prediction of brain tumors' response to radiation therapy using high b-value diffusion-weighted MRI. Neoplasia 6:136-142
    • (2004) Neoplasia , vol.6 , pp. 136-142
    • Mardor, Y.1    Roth, Y.2    Ochershvilli, A.3
  • 67
    • 2442468880 scopus 로고    scopus 로고
    • The impact of tumour volume and surgery on the outcome of adults with supratentorial WHO grade II astrocytomas and oligoastrocytomas
    • Mariani L, Siegenthaler P, Guzman R et al (2004) The impact of tumour volume and surgery on the outcome of adults with supratentorial WHO grade II astrocytomas and oligoastrocytomas. Acta Neurochir (Wien) 146:441-448
    • (2004) Acta Neurochir (Wien) , vol.146 , pp. 441-448
    • Mariani, L.1    Siegenthaler, P.2    Guzman, R.3
  • 68
    • 12944315014 scopus 로고    scopus 로고
    • Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: Results of a phase i trial
    • Markert JM, Medlock MD, Rabkin SD et al (2000) Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial. Gene Ther 7: 867-874
    • (2000) Gene Ther , vol.7 , pp. 867-874
    • Markert, J.M.1    Medlock, M.D.2    Rabkin, S.D.3
  • 70
    • 0347615101 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer and liver metastases: Results from two phase i studies
    • Morgan B, Thomas AL, Drevs J et al (2003) Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer and liver metastases: results from two phase I studies. J Clin Oncol 21:3955-3964
    • (2003) J Clin Oncol , vol.21 , pp. 3955-3964
    • Morgan, B.1    Thomas, A.L.2    Drevs, J.3
  • 72
    • 0033000339 scopus 로고    scopus 로고
    • Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: A pilot study in humans
    • Palu G, Cavaggioni A, Calvi P et al (1999) Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: a pilot study in humans. Gene Ther 6:330-337
    • (1999) Gene Ther , vol.6 , pp. 330-337
    • Palu, G.1    Cavaggioni, A.2    Calvi, P.3
  • 73
    • 85047699172 scopus 로고    scopus 로고
    • The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: A proof of principle study
    • Papanastassiou V, Rampling R, Fraser M et al (2002) The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle study. Gene Ther 9:398-406
    • (2002) Gene Ther , vol.9 , pp. 398-406
    • Papanastassiou, V.1    Rampling, R.2    Fraser, M.3
  • 74
    • 2342457057 scopus 로고    scopus 로고
    • Comparison of O-(2-18F-fluoroethyl)-L-tyrosine PET and 3-123I-iodo-alpha-methyl-L-tyrosine SPECT in brain tumors
    • Pauleit D, Floeth F, Tellmann L et al (2004) Comparison of O-(2-18F-fluoroethyl)-L-tyrosine PET and 3-123I-iodo-alpha-methyl-L-tyrosine SPECT in brain tumors. J Nucl Med 45:374-381
    • (2004) J Nucl Med , vol.45 , pp. 374-381
    • Pauleit, D.1    Floeth, F.2    Tellmann, L.3
  • 75
    • 0034126959 scopus 로고    scopus 로고
    • PET: The merging of biology and imaging into molecular imaging
    • Phelps ME (2000) PET: the merging of biology and imaging into molecular imaging. J Nucl Med 41:661-681
    • (2000) J Nucl Med , vol.41 , pp. 661-681
    • Phelps, M.E.1
  • 76
  • 78
    • 25144492058 scopus 로고    scopus 로고
    • O-(2-[18F]fluoroethyl)-L-tyrosine PET for monitoring the effects of convection-enhanced delivery of paclitaxel in patients with recurrent glioblastoma
    • Popperl G, Goldbrunner R, Gildehaus FJ et al (2005) O-(2-[18F] fluoroethyl)-L-tyrosine PET for monitoring the effects of convection-enhanced delivery of paclitaxel in patients with recurrent glioblastoma. Eur J Nucl Med Mol Imaging 32:1018-1025
    • (2005) Eur J Nucl Med Mol Imaging , vol.32 , pp. 1018-1025
    • Popperl, G.1    Goldbrunner, R.2    Gildehaus, F.J.3
  • 79
    • 0002065461 scopus 로고    scopus 로고
    • Epidemiology
    • Berger MS, Wilson CD (Eds). Saunders, Philadelphia, Pp
    • Preston-Martin S (1999) Epidemiology. In Berger MS, Wilson CD (eds) The gliomas. Saunders, Philadelphia, pp 2-11
    • (1999) The Gliomas , pp. 2-11
    • Preston-Martin, S.1
  • 80
    • 3242776853 scopus 로고    scopus 로고
    • Peritumoral brain regions in gliomas and meningiomas: Investigation with isotropic diffusion-weighted MR imaging and diffusion-tensor MR imaging
    • Provenzale JM, McGraw P, Mhatre P, Guo AC, Delong D (2004) Peritumoral brain regions in gliomas and meningiomas: investigation with isotropic diffusion-weighted MR imaging and diffusion-tensor MR imaging. Radiology 232:451-460
    • (2004) Radiology , vol.232 , pp. 451-460
    • Provenzale, J.M.1    McGraw, P.2    Mhatre, P.3    Guo, A.C.4    Delong, D.5
  • 81
    • 0034694011 scopus 로고    scopus 로고
    • A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme
    • Rainov NG (2000) A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum Gene Ther 11:2389-2401
    • (2000) Hum Gene Ther , vol.11 , pp. 2389-2401
    • Rainov, N.G.1
  • 82
    • 0031463632 scopus 로고    scopus 로고
    • Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells
    • Ram Z, Culver KW, Oshiro EM et al (1997) Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nat Med 3:1354-1361
    • (1997) Nat Med , vol.3 , pp. 1354-1361
    • Ram, Z.1    Culver, K.W.2    Oshiro, E.M.3
  • 83
    • 12944272092 scopus 로고    scopus 로고
    • Toxicity evaluation of replicationcompetent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma
    • Rampling R, Cruickshank G, Papanastassiou V et al (2000) Toxicity evaluation of replicationcompetent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma. Gene Ther 7:859-866
    • (2000) Gene Ther , vol.7 , pp. 859-866
    • Rampling, R.1    Cruickshank, G.2    Papanastassiou, V.3
  • 84
    • 1242338786 scopus 로고    scopus 로고
    • Imaging tri-fusion multimodality reporter gene expression in living subjects
    • Ray P, De A, Min JJ, Tsien RY, Gambhir SS (2004) Imaging tri-fusion multimodality reporter gene expression in living subjects. Cancer Res 64:1323-1330
    • (2004) Cancer Res , vol.64 , pp. 1323-1330
    • Ray, P.1    De, A.2    Min, J.J.3    Tsien, R.Y.4    Gambhir, S.S.5
  • 85
    • 0035883412 scopus 로고    scopus 로고
    • Positron emission tomography (11)C-methionine and survival in patients with low-grade gliomas
    • Ribom D, Eriksson A, Hartman M et al (2001) Positron emission tomography (11)C-methionine and survival in patients with low-grade gliomas. Cancer 92:1541-1549
    • (2001) Cancer , vol.92 , pp. 1541-1549
    • Ribom, D.1    Eriksson, A.2    Hartman, M.3
  • 86
    • 0033984339 scopus 로고    scopus 로고
    • Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization
    • Rogulski KR, Wing MS, Paielli DL, Gilbert JD, Kim JH, Freytag SO (2000) Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization. Hum.Gene Ther 11:67-76
    • (2000) Hum.Gene Ther , vol.11 , pp. 67-76
    • Rogulski, K.R.1    Wing, M.S.2    Paielli, D.L.3    Gilbert, J.D.4    Kim, J.H.5    Freytag, S.O.6
  • 87
    • 0029044821 scopus 로고
    • Assessment of ganciclovir toxicity to experimental intracranial gliomas following recombinant adenoviral-mediated transfer of the herpes simplex virus thymidine kinase gene by magnetic resonance imaging and proton magnetic resonance spectroscopy
    • Ross BD, Kim B, Davidson BL (1995) Assessment of ganciclovir toxicity to experimental intracranial gliomas following recombinant adenoviral-mediated transfer of the herpes simplex virus thymidine kinase gene by magnetic resonance imaging and proton magnetic resonance spectroscopy. Clin Cancer Res 1:651-657
    • (1995) Clin Cancer Res , vol.1 , pp. 651-657
    • Ross, B.D.1    Kim, B.2    Davidson, B.L.3
  • 88
    • 4344567362 scopus 로고    scopus 로고
    • Molecular imaging of temporal dynamics and spatial heterogeneity of hypoxia-inducible factor-1 signal transduction activity in tumors in living mice
    • Serganova I, Doubrovin M, Vider J et al (2004) Molecular imaging of temporal dynamics and spatial heterogeneity of hypoxia-inducible factor-1 signal transduction activity in tumors in living mice. Cancer Res 64:6101-6108
    • (2004) Cancer Res , vol.64 , pp. 6101-6108
    • Serganova, I.1    Doubrovin, M.2    Vider, J.3
  • 89
    • 0033588816 scopus 로고    scopus 로고
    • A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir
    • Shand N, Weber F, Mariani L et al (1999) A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group. Hum Gene Ther 10: 2325-2335
    • (1999) GLI328 European-Canadian Study Group. Hum Gene Ther , vol.10 , pp. 2325-2335
    • Shand, N.1    Weber, F.2    Mariani, L.3
  • 90
    • 0031790264 scopus 로고    scopus 로고
    • Imaging proliferation in vivo with [F-18]FLT and positron emission tomography
    • Shields AF, Grierson JR, Dohmen BM et al (1998) Imaging proliferation in vivo with [F-18]FLT and positron emission tomography. Nat Med 4:1334-1336
    • (1998) Nat Med , vol.4 , pp. 1334-1336
    • Shields, A.F.1    Grierson, J.R.2    Dohmen, B.M.3
  • 92
    • 10844239971 scopus 로고    scopus 로고
    • Positron emission tomography (PET) imaging of tumor-localized Salmonella expressing HSV1-TK
    • Soghomonyan SA, Doubrovin M, Pike J et al (2005) Positron emission tomography (PET) imaging of tumor-localized Salmonella expressing HSV1-TK. Cancer Gene Ther 12:101-108
    • (2005) Cancer Gene Ther , vol.12 , pp. 101-108
    • Soghomonyan, S.A.1    Doubrovin, M.2    Pike, J.3
  • 93
    • 0017368491 scopus 로고
    • The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: Theory, procedure, and normal values in the conscious and anesthetized albino rat
    • Sokoloff L, Reivich M, Kennedy C et al (1977) The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem 28:897-916
    • (1977) J Neurochem , vol.28 , pp. 897-916
    • Sokoloff, L.1    Reivich, M.2    Kennedy, C.3
  • 94
    • 1842429022 scopus 로고    scopus 로고
    • MicroPET imaging of Cre-loxP-mediated conditional activation of a herpes simplex virus type 1 thymidine kinase reporter gene
    • Sundaresan G, Paulmurugan R, Berger F et al (2004) MicroPET imaging of Cre-loxP-mediated conditional activation of a herpes simplex virus type 1 thymidine kinase reporter gene. Gene Ther 11:609-618
    • (2004) Gene Ther , vol.11 , pp. 609-618
    • Sundaresan, G.1    Paulmurugan, R.2    Berger, F.3
  • 95
    • 20144377354 scopus 로고    scopus 로고
    • Semi-quantification of methionine uptake and flair signal for the evaluation of chemotherapy in low-grade oligodendroglioma
    • Tang BN, Sadeghi N, Branle F, De Witte O, Wikler D, Goldman S (2005) Semi-quantification of methionine uptake and flair signal for the evaluation of chemotherapy in low-grade oligodendroglioma. J Neurooncol 71:161-168
    • (2005) J Neurooncol , vol.71 , pp. 161-168
    • Tang, B.N.1    Sadeghi, N.2    Branle, F.3    De Witte, O.4    Wikler, D.5    Goldman, S.6
  • 96
    • 0028802564 scopus 로고
    • Imaging the expression of transfected genes in vivo
    • Tjuvajev JG, Stockhammer G, Desai R et al (1995) Imaging the expression of transfected genes in vivo. Cancer Res 55:6126-6132
    • (1995) Cancer Res , vol.55 , pp. 6126-6132
    • Tjuvajev, J.G.1    Stockhammer, G.2    Desai, R.3
  • 97
    • 9544242826 scopus 로고    scopus 로고
    • Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: A potential method for monitoring clinical gene therapy
    • Tjuvajev JG, Finn R, Watanabe K et al (1996) Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy. Cancer Res 56:4087-4095
    • (1996) Cancer Res , vol.56 , pp. 4087-4095
    • Tjuvajev, J.G.1    Finn, R.2    Watanabe, K.3
  • 98
    • 17144471900 scopus 로고    scopus 로고
    • Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography
    • Tjuvajev JG, Avril N, Oku T et al (1998) Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography. Cancer Res 58:4333-4341
    • (1998) Cancer Res , vol.58 , pp. 4333-4341
    • Tjuvajev, J.G.1    Avril, N.2    Oku, T.3
  • 99
    • 0033205584 scopus 로고    scopus 로고
    • A general approach to the non-invasive imaging of transgenes using cis-linked herpes simplex virus thymidine kinase
    • Tjuvajev JG, Joshi A, Callegari J et al (1999) A general approach to the non-invasive imaging of transgenes using cis-linked herpes simplex virus thymidine kinase. Neoplasia 1:315-320
    • (1999) Neoplasia , vol.1 , pp. 315-320
    • Tjuvajev, J.G.1    Joshi, A.2    Callegari, J.3
  • 100
    • 0032505773 scopus 로고    scopus 로고
    • Treatment of human breast cancer in a brain metastatic model by G207, a replication-competent multimutated herpes simplex virus 1
    • Toda M, Rabkin SD, Martuza RL (1998) Treatment of human breast cancer in a brain metastatic model by G207, a replication-competent multimutated herpes simplex virus 1. Hum Gene Ther 9:2177-2185
    • (1998) Hum Gene Ther , vol.9 , pp. 2177-2185
    • Toda, M.1    Rabkin, S.D.2    Martuza, R.L.3
  • 101
    • 0033589694 scopus 로고    scopus 로고
    • Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus
    • Todo T, Rabkin SD, Sundaresan P et al (1999) Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus. Hum Gene Ther 10:2741-2755
    • (1999) Hum Gene Ther , vol.10 , pp. 2741-2755
    • Todo, T.1    Rabkin, S.D.2    Sundaresan, P.3
  • 102
    • 0034085545 scopus 로고    scopus 로고
    • Evaluation of early response to SU101 target-based therapy in patients with recurrent supratentorial malignant gliomas using FDG PET and Gd-DTPA MRI
    • Vlassenko AG, Thiessen B, Beattie BJ, Malkin MG, Blasberg RG (2000) Evaluation of early response to SU101 target-based therapy in patients with recurrent supratentorial malignant gliomas using FDG PET and Gd-DTPA MRI. J Neurooncol 46:249-259
    • (2000) J Neurooncol , vol.46 , pp. 249-259
    • Vlassenko, A.G.1    Thiessen, B.2    Beattie, B.J.3    Malkin, M.G.4    Blasberg, R.G.5
  • 103
    • 0141870056 scopus 로고    scopus 로고
    • Imaging-guided convection-enhanced delivery and gene therapy of glioblastoma
    • Voges J, Reszka R, Gossmann A et al(2003) Imaging-guided convection-enhanced delivery and gene therapy of glioblastoma. Ann Neurol 54:479-487
    • (2003) Ann Neurol , vol.54 , pp. 479-487
    • Voges, J.1    Reszka, R.2    Gossmann, A.3
  • 104
    • 0037432287 scopus 로고    scopus 로고
    • Interobserver variability in the radiological assessment of response to chemotherapy in glioma
    • Vos MJ, Uitdehaag BM, Barkhof F et al (2003) Interobserver variability in the radiological assessment of response to chemotherapy in glioma. Neurology 60:826-830
    • (2003) Neurology , vol.60 , pp. 826-830
    • Vos, M.J.1    Uitdehaag, B.M.2    Barkhof, F.3
  • 105
    • 0034062857 scopus 로고    scopus 로고
    • In vivo magnetic resonance imaging of transgene expression
    • Weissleder R, Moore A, Mahmood U et al (2000) In vivo magnetic resonance imaging of transgene expression. Nat Med 6:351-355
    • (2000) Nat Med , vol.6 , pp. 351-355
    • Weissleder, R.1    Moore, A.2    Mahmood, U.3
  • 106
    • 9944256262 scopus 로고    scopus 로고
    • A preclinical model for noninvasive imaging of hypoxia-induced gene expression; Comparison with an exogenous marker of tumor hypoxia
    • Wen B, Burgman P, Zanzonico P et al (2004) A preclinical model for noninvasive imaging of hypoxia-induced gene expression; comparison with an exogenous marker of tumor hypoxia. Eur J Nucl Med Mol Imaging 31:1530-1538
    • (2004) Eur J Nucl Med Mol Imaging , vol.31 , pp. 1530-1538
    • Wen, B.1    Burgman, P.2    Zanzonico, P.3
  • 107
    • 0034747395 scopus 로고    scopus 로고
    • Enzyme-targeted, nucleoside-based radiopharmaceuticals for scintigraphic monitoring of gene transfer and expression
    • Wiebe LI, Knaus EE (2001) Enzyme-targeted, nucleoside-based radiopharmaceuticals for scintigraphic monitoring of gene transfer and expression. Curr Pharm Des 7:1893-1906
    • (2001) Curr Pharm des , vol.7 , pp. 1893-1906
    • Wiebe, L.I.1    Knaus, E.E.2
  • 108
    • 0029962290 scopus 로고    scopus 로고
    • Glucose consumption and methionine uptake in lowgrade gliomas after iodine-125 brachytherapy
    • Wurker M, Herholz K, Voges J et al (1996) Glucose consumption and methionine uptake in lowgrade gliomas after iodine-125 brachytherapy. Eur J Nucl Med 23:583-586
    • (1996) Eur J Nucl Med , vol.23 , pp. 583-586
    • Wurker, M.1    Herholz, K.2    Voges, J.3
  • 109
    • 14644408765 scopus 로고    scopus 로고
    • Imaging progress of herpes simplex virus type 1 thymidine kinase suicide gene therapy in living subjects with positron emission tomography
    • Yaghoubi SS, Barrio JR, Namavari M et al (2005) Imaging progress of herpes simplex virus type 1 thymidine kinase suicide gene therapy in living subjects with positron emission tomography. Cancer Gene Ther 12:329-339
    • (2005) Cancer Gene Ther , vol.12 , pp. 329-339
    • Yaghoubi, S.S.1    Barrio, J.R.2    Namavari, M.3


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