Chapter Twenty-Two Mechanisms and Methods in Glucose Metabolism and Cell Death

Methods in Enzymology

Volumn 442, Issue , 2008, Pages 439-457

  Zhao, Yuxing ^a   Wieman, Heather L ^a   Jacobs, Sarah R ^a   Rathmell, Jeffrey C ^a  

^a DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER 1; PROTEIN BCL 2; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; PRASTERONE;

APOPTOSIS; CELL DEATH; CELL METABOLISM; ENZYME INHIBITION; GENE OVEREXPRESSION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCOLYSIS; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; REVIEW; ANIMAL; ARTICLE; CARBOHYDRATE METABOLISM; DRUG EFFECT; METABOLISM; PHYSIOLOGY;

ANIMALS; APOPTOSIS; CARBOHYDRATE METABOLISM; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; CELL DEATH; DEHYDROEPIANDROSTERONE; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; HUMANS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 52049110035     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(08)01422-5     Document Type: Review

References (50)

1. Alves N.L., Derks I.A., Berk E., Spijker R., van Lier R.A., and Eldering E. The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells. Immunity 24 (2006) 703-716
2. Asano T., Katagiri H., Takata K., Lin J.L., Ishihara H., Inukai K., Tsukuda K., Kikuchi M., Hirano H., Yazaki Y., and Oka Y. The role of N-glycosylation of GLUT1 for glucose transport activity. J. Biol. Chem. 266 (1991) 24632-24636
3. Bensaad K., Tsuruta A., Selak M.A., Vidal M.N., Nakano K., Bartrons R., Gottlieb E., and Vousden K.H. TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell 126 (2006) 107-120
4. Bentley J., Walker I., McIntosh E., Whetton A.D., Owen-Lynch P.J., and Baldwin S.A. Glucose transport regulation by p210 Bcr-Abl in a chronic myeloid leukaemia model. Br. J. Haematol. 112 (2001) 212-215
5. Budihardjo I., Oliver H., Lutter M., Luo X., and Wang X. Biochemical pathways of caspase activation during apoptosis. Annu. Rev. Cell Dev. Biol. 15 (1999) 269-290
6. Byfield M.P., Murray J.T., and Backer J.M. hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase. J. Biol. Chem. 280 (2005) 33076-33082
7. Callaghan M.J., Ceradini D.J., and Gurtner G.C. Hyperglycemia-induced reactive oxygen species and impaired endothelial progenitor cell function. Antioxid. Redox Signal 7 (2005) 1476-1482
8. Campbell M., Allen W.E., Sawyer C., Vanhaesebroeck B., and Trimble E.R. Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways. Circ. Res. 95 (2004) 380-388
9. Chi M.M., Pingsterhaus J., Carayannopoulos M., and Moley K.H. Decreased glucose transporter expression triggers BAX-dependent apoptosis in the murine blastocyst. J. Biol. Chem. 275 (2000) 40252-40257
10. Danial N.N., and Korsmeyer S.J. Cell death: Critical control points. Cell 116 (2004) 205-219
11. De Luca T., Morre D.M., Zhao H., and Morre D.J. NAD+/NADH and/or CoQ/CoQH2 ratios from plasma membrane electron transport may determine ceramide and sphingosine-1-phosphate levels accompanying G1 arrest and apoptosis. Biofactors 25 (2005) 43-60
12. Edinger A.L., and Thompson C.B. Death by design: Apoptosis, necrosis and autophagy. Curr. Opin. Cell Biol. 16 (2004) 663-669
13. Edinger A.L., Cinalli R.M., and Thompson C.B. Rab7 prevents growth factor-independent survival by inhibiting cell-autonomous nutrient transporter expression. Dev. Cell 5 (2003) 571-582
14. Frauwirth K.A., and Thompson C.B. Regulation of T lymphocyte metabolism. J. Immunol. 172 (2004) 4661-4665
15. Gatenby R.A., and Gillies R.J. Why do cancers have high aerobic glycolysis?. Nat. Rev. Cancer 4 (2004) 891-899
16. Gottlob K., Majewski N., Kennedy S., Kandel E., Robey R.B., and Hay N. Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. Genes Dev. 15 (2001) 1406-1418
17. Haberkorn U., Altmann A., Kamencic H., Morr I., Traut U., Henze M., Jiang S., Metz J., and Kinscherf R. Glucose transport and apoptosis after gene therapy with HSV thymidine kinase. Eur. J. Nucl. Med. 28 (2001) 1690-1696
18. Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 (2000) 57-70
19. Henquin J.C. Triggering and amplifying pathways of regulation of insulin secretion by glucose. Diabetes 49 (2000) 1751-1760
20. Jones R.G., Plas D.R., Kubek S., Buzzai M., Mu J., Xu Y., Birnbaum M.J., and Thompson C.B. AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol. Cell 18 (2005) 283-293
21. Kuan C.Y., Whitmarsh A.J., Yang D.D., Liao G., Schloemer A.J., Dong C., Bao J., Banasiak K.J., Haddad G.G., Flavell R.A., Davis R.J., and Rakic P. Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Proc. Natl. Acad. Sci. USA 100 (2003) 15184-15189
22. Lang F., Lang K.S., Lang P.A., Huber S.M., and Wieder T. Mechanisms and significance of eryptosis. Antioxid. Redox Signal 8 (2006) 1183-1192
23. Leist M., Single B., Castoldi A.F., Kuhnle S., and Nicotera P. Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis. J. Exp. Med. 185 (1997) 1481-1486
24. Lieberthal W., Menza S.A., and Levine J.S. Graded ATP depletion can cause necrosis or apoptosis of cultured mouse proximal tubular cells. Am. J. Physiol. 274 (1998) F315-F327
25. Lum J.J., Bauer D.E., Kong M., Harris M.H., Li C., Lindsten T., and Thompson C.B. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 120 (2005) 237-248
26. Lum J.J., DeBerardinis R.J., and Thompson C.B. Autophagy in metazoans: Cell survival in the land of plenty. Nat. Rev. Mol. Cell Biol. 6 (2005) 439-448
27. Majewski N., Nogueira V., Bhaskar P., Coy P.E., Skeen J.E., Gottlob K., Chandel N.S., Thompson C.B., Robey R.B., and Hay N. Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. Mol. Cell 16 (2004) 819-830
28. Morissette M.R., Howes A.L., Zhang T., and Heller Brown J. Upregulation of GLUT1 expression is necessary for hypertrophy and survival of neonatal rat cardiomyocytes. J. Mol. Cell. Cardiol. 35 (2003) 1217-1227
29. Mourrieras F., Foufelle F., Foretz M., Morin J., Bouche S., and Ferre P. Induction of fatty acid synthase and S14 gene expression by glucose, xylitol and dihydroxyacetone in cultured rat hepatocytes is closely correlated with glucose 6-phosphate concentrations. Biochem. J. 326 Pt 2 (1997) 345-349
30. Nutt L.K., Margolis S.S., Jensen M., Herman C.E., Dunphy W.G., Rathmell J.C., and Kornbluth S. Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2. Cell 123 (2005) 89-103
31. Puthalakath H., O'Reilly L.A., Gunn P., Lee L., Kelly P.N., Huntington N.D., Hughes P.D., Michalak E.M., McKimm-Breschkin J., Motoyama N., Gotoh T., Akira S., et al. ER stress triggers apoptosis by activating BH3-only protein Bim. Cell 129 (2007) 1337-1349
32. Rathmell J.C., Elstrom R.L., Cinalli R.M., and Thompson C.B. Activated Akt promotes increased resting T cell size, CD28-independent T cell growth, and development of autoimmunity and lymphoma. Eur. J. Immunol. 33 (2003) 2223-2232
33. Rathmell J.C., Fox C.J., Plas D.R., Hammerman P., Cinalli R.M., and Thompson C.B. Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival. Mol. Cell. Biol. 23 (2003) 7315-7328
34. Rathmell J.C., Vander Heiden M.G., Harris M.H., Frauwirth K.A., and Thompson C.B. In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. Mol. Cell 6 (2000) 683-692
35. Reimertz C., Kogel D., Rami A., Chittenden T., and Prehn J.H. Gene expression during ER stress-induced apoptosis in neurons: Induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J. Cell Biol. 162 (2003) 587-597
36. Sade H., and Sarin A. Reactive oxygen species regulate quiescent T-cell apoptosis via the BH3-only proapoptotic protein BIM. Cell Death Differ. 11 (2004) 416-423
37. Semenza G.L., Artemov D., Bedi A., Bhujwalla Z., Chiles K., Feldser D., Laughner E., Ravi R., Simons J., Taghavi P., and Zhong H. 'The metabolism of tumours': 70 years later. Novartis Found Symp 240 (2001) 251-260 discussion 60-64
38. Shintani T., and Klionsky D.J. Autophagy in health and disease: A double-edged sword. Science 306 (2004) 990-995
39. Smith T.A. Mammalian hexokinases and their abnormal expression in cancer. Br. J. Biomed. Sci. 57 (2000) 170-178
40. Valverde A.M., Navarro P., Benito M., and Lorenzo M. H-ras induces glucose uptake in brown adipocytes in an insulin- and phosphatidylinositol 3-kinase-independent manner. Exp. Cell Res. 243 (1998) 274-281
41. Vander Heiden M.G., Plas D.R., Rathmell J.C., Fox C.J., Harris M.H., and Thompson C.B. Growth factors can influence cell growth and survival through effects on glucose metabolism. Mol. Cell. Biol. 21 (2001) 5899-5912
42. Warburg O. On the origin of cancer cells. Science 123 (1956) 309-314
43. Ward M.W., Huber H.J., Weisova P., Dussmann H., Nicholls D.G., and Prehn J.H. Mitochondrial and plasma membrane potential of cultured cerebellar neurons during glutamate-induced necrosis, apoptosis, and tolerance. J. Neurosci. 27 (2007) 8238-8249
44. Wieman H.L., Wofford J.A., and Rathmell J.C. Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking. Mol. Biol. Cell 18 (2007) 1437-1446
45. Wilson J.E. Isozymes of mammalian hexokinase: Structure, subcellular localization and metabolic function. J. Exp. Biol. 206 (2003) 2049-2057
46. Wolin M.S., Ahmad M., Gao Q., and Gupte S.A. Cytosolic NAD(P)H regulation of redox signaling and vascular oxygen sensing. Antioxid. Redox Signal 9 (2007) 671-678
47. Younes M., Brown R.W., Stephenson M., Gondo M., and Cagle P.T. Overexpression of Glut1 and Glut3 in stage I nonsmall cell lung carcinoma is associated with poor survival. Cancer 80 (1997) 1046-1051
48. Zamaraeva M.V., Sabirov R.Z., Maeno E., Ando-Akatsuka Y., Bessonova S.V., and Okada Y. Cells die with increased cytosolic ATP during apoptosis: A bioluminescence study with intracellular luciferase. Cell Death Differ 12 (2005) 1390-1397
49. Zhao Y., Altman B.J., Coloff J.L., Herman C.E., Jacobs S.R., Wieman H.L., Wofford J.A., Dimascio L.N., Ilkayeva O., Kelekar A., Reya T., and Rathmell J.C. Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. Mol. Cell. Biol. 27 (2007) 4328-4339
50. Zhou R., Vander Heiden M.G., and Rudin C.M. Genotoxic exposure is associated with alterations in glucose uptake and metabolism. Cancer Res. 62 (2002) 3515-3520