TRPA1 channels mediate cold temperature sensing in mammalian vagal sensory neurons: Pharmacological and genetic evidence

Journal of Neuroscience

Volumn 28, Issue 31, 2008, Pages 7863-7875

  Fajardo, Otto ^a   Meseguer, Victor ^a   Belmonte, Carlos ^a   Viana, Félix ^a  

^a INSTITUTO DE NEUROCIENCIAS   (Spain)

Author keywords

Laryngeal afferents; Nociceptor; Nodose ganglion; Noxious cold; Thermotransduction; TRP channel

Indexed keywords

1 (2 HYDROXYPHENYL) 4 (3 NITROPHENYL) 1,2,3,6 TETRAHYDROPYRIMIDIN 2 ONE; [2 (1,3 DIMETHYL 2,6 DIOXO 1,2,3,6 TETRAHYDRO 7H PURIN 7 YL) N (4 ISOPROPYLPHENYL)ACETAMIDE]; [4 (3 CHLOROPYRIDIN 2 YL) PIPERAZINE 1 CARBOXYLIC ACID (4 TERTBUTYLPHENYL) AMIDE]; ACETAMIDE DERIVATIVE; AMIDE; CAMPHOR; CAPSAICIN; CINNAMALDEHYDE; MENTHOL; RUTHENIUM RED; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; UNCLASSIFIED DRUG; ANKTM1 PROTEIN, MOUSE; CALCIUM; NERVE GROWTH FACTOR;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CALCIUM CELL LEVEL; COLD SENSITIVITY; CONTROLLED STUDY; COOLING; EVOKED RESPONSE; GENETIC ASSOCIATION; HEAT; HEAT SENSITIVITY; MALE; MAMMAL; MOUSE; NERVE CELL EXCITABILITY; NOCICEPTIVE STIMULATION; NODOSE GANGLION; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY NERVE; SOMATIC CELL; TEMPERATURE SENSITIVITY; THERMORECEPTOR; VAGUS NERVE; VAGUS NERVE STIMULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINE; CHO CELL; COLD; COMPARATIVE STUDY; CRICETULUS; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; HAMSTER; HUMAN; MOUSE MUTANT; PHYSIOLOGY; SENSORY NERVE CELL; SPRAGUE DAWLEY RAT; TEMPERATURE SENSE;

ANIMALS; CALCIUM; CELL LINE; CELLS, CULTURED; CHO CELLS; COLD; CRICETINAE; CRICETULUS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE GROWTH FACTOR; NEURONS, AFFERENT; RATS; RATS, SPRAGUE-DAWLEY; TEMPERATURE SENSE; TRANSIENT RECEPTOR POTENTIAL CHANNELS; VAGUS NERVE;

EID: 50349100515     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1696-08.2008     Document Type: Article

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