Cardiac nociceptors innervated by vagal afferents in rats

Autonomic Neuroscience: Basic and Clinical

Volumn 126-127, Issue , 2006, Pages 174-178

  Hisata, Yoichi ^a   Zeredo, Jorge L ^a   Eishi, Kiyoyuki ^a   Toda, Kazuo ^a  

^a Grad Sch Biomed Sci   (Japan)

Author keywords

Angina pectoris; Cardiac pain; Polymodal nociceptor; Rat; Receptive field; Vagal nerve

Indexed keywords

BRADYKININ;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL VENTILATION; ELECTROSTIMULATION; HEART; INNERVATION; MECHANICAL STIMULATION; NERVE CONDUCTION; NOCICEPTIVE RECEPTOR; NONHUMAN; PRIORITY JOURNAL; RAT; VAGUS NERVE;

ACTION POTENTIALS; ANIMALS; BRADYKININ; HEART; NERVE FIBERS; NEURONS, AFFERENT; NOCICEPTORS; PAIN MEASUREMENT; PAIN THRESHOLD; PHYSICAL STIMULATION; RATS; RATS, WISTAR; STIMULATION, CHEMICAL; VAGUS NERVE; VASODILATOR AGENTS;

EID: 33744537127     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autneu.2006.02.008     Document Type: Article

References (25)

1. Baker D.G., Coleridge H.M., Coleridge J.C., and Nerdrum T. Search for a cardiac nociceptor: stimulation by bradykinin of sympathetic afferent nerve endings in the heart of the cat. J. Physiol. (Lond.) 306 (1980) 519-536
2. Barber M.J., Mueller T.M., Davies B.G., and Zipes D.P. Phenol topically applied to canine left ventricular epicardium interrupts sympathetic but not vagal afferents. Circ. Res. 55 (1984) 532-544
3. Bassenge E., and Munzel T. Cardiac mechanisms for the development of angina pectoris pain. Z. Kardiol. 77 Suppl. 5 (1988) 5-14
4. Benson C.J., Eckert S.P., and McCleskey E.W. Acid-evoked currents in cardiac sensory neurons: a possible mediator of myocardial ischemic sensation. Circ. Res. 84 (1999) 921-928
5. Crea F., and Gaspardone A. New look to an old symptom: angina pectoris. Circulation 96 (1997) 3766-3773
6. Ditting T., Hilgers K.F., Scrogin K.E., Stetter A., Linz P., and Veelken R. Mecanosensitive cardiac C-fiber response to change in ventricular filling, coronary perfusion pressure, hemorrhage, and volume expansion in rats. Am. J. Physiol., Heart Circ. Physiol. 288 (2004) H541-H552
7. Foreman R.D. Mechanisms of cardiac pain. Annu. Rev. Physiol. 61 (1999) 143-167
8. Koltzenburg M., Kress M., and Reeh P.W. The nociceptor sensitization by bradykinin does not depend on sympathetic neurons. Neuroscience 46 (1992) 465-473
9. Kumazawa T., and Mizumura K. Thin-fibre receptors responding to mechanical, chemical, and thermal stimulation in the skeletal muscle of the dog. J. Physiol. (Lond.) 273 (1977) 179-194
10. Kumazawa T., and Mizumura K. Chemical responses of polymodal receptors of the scrotal contents in dogs. J. Physiol. 299 (1980) 219-231
11. Kumazawa T., Mizumura K., and Sato J. Response properties of polymodal receptors studied using in vitro testis superior spermatic nerve preparations of dogs. J. Neurophysiol. 57 (1987) 702-711
12. Lombardi F., Della Bella P., Casati R., and Malliani A. Effects of intracoronary administration of bradykinin on the impulse activity of afferent sympathetic unmyelinated fibers with left ventricular endings in the cat. Circ. Res. 48 (1981) 69-75
13. Meller S.T., and Gebhart G.F. A critical review of the afferent pathways and the potential chemical mediators involved in cardiac pain. Neuroscience 48 (1992) 501-524
14. Meller S.T., Lewis S.J., Ness T.J., Brody M.J., and Gebhart G.F. Vagal afferent-mediated inhibition of a nociceptive reflex by intravenous serotonin in the rat: I. Characterization. Brain Res. 524 (1990) 90-100
15. Minisi A.J., and Thames M.D. Distribution of left ventricular sympathetic afferents demonstrated by reflex responses to transmural myocardial ischemia and to intracoronary and epicardial bradykinin. Circulation 87 (1993) 240-246
16. Mody V.H., and Faxon D.P. Management of unstable angina: integrating the new approaches. Rev. Cardiovasc. Med. 1 (2000) 104-119
17. Nerdrum T., Baker D.G., Coleridge H.M., and Coleridge J.C. Interaction of bradykinin and prostaglandin E1 on cardiac pressor reflex and sympathetic afferents. Am. J. Physiol. 250 (1986) R815-R822
18. Pan H.L., and Chen S.R. Myocardial ischemia recruits mechanically insensitive cardiac sympathetic afferents in cats. J. Neurophysiol. 87 (2002) 660-668
19. Perl E.R. Afferent basis of nociception and pain: evidence from the characteristics of sensory receptors and their projections to the spinal dorsal horn. Res. Publ. - Assoc. Res. Nerv. Ment. Dis. 58 (1980) 19-45
20. Qin C., Chandler M.J., Miller K.E., and Foreman R.D. Responses and afferent pathways of superficial and deeper c(1)-c(2) spinal cells to intrapericardial algogenic chemicals in rats. J. Neurophysiol. 85 (2001) 1522-1532
21. Russek H.I. Intractable angina pectoris. Med. Clin. North Am. 54 (1970) 333-348
22. Takeuchi Y., Ishii N., and Toda K. An in vitro temporomandibular joint-nerve preparation for pain study in rats. J. Neurosci. Methods 109 (2001) 123-128
23. Toda K., Ishii N., and Nakamura Y. Characteristics of mucosal nociceptors in the rat oral cavity: an in vitro study. Neurosci. Lett. 228 (1997) 95-98
24. Veelken R., Stetter A., Dickel T., and Hilgers K.F. Bimodality of cardiac vagal afferent C-fibres in the rat. Pflugers Arch. 446 (2003) 516-522
25. Zimmermann M. Physiological mechanisms of pain and pain therapy. Triangle 20 (1981) 7-18