Epithelial-mesenchymal transition downregulates laminin α5 chain and upregulates laminin α4 chain in oral squamous carcinoma cells

Histochemistry and Cell Biology

Volumn 130, Issue 3, 2008, Pages 509-525

  Takkunen, Minna ^a   Ainola, Mari ^b   Vainionpää, Noora ^a   Grenman, Reidar ^c   Patarroyo, Manuel ^d   García De Herreros, Antonio ^e   Konttinen, Yrjö T ^b,f,g   Virtanen, Ismo ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c TURKU UNIVERSITY HOSPITAL   (Finland)

^d KAROLINSKA INSTITUTE   (Sweden)

^e HOSPITAL DEL MAR   (Spain)

^f ORTON ORTHOPAEDIC HOSPITAL   (Finland)

^g COXA Hospital for Joint Replacement ^*  (Finland)

Author keywords

Basement membrane; Epithelial mesenchymal transition; Laminin 4 chain; Laminin 5 chain; Oral squamous cell carcinoma; Snail

Indexed keywords

ALPHA6BETA4 INTEGRIN; FIBRONECTIN; INTEGRIN LINKED KINASE; LAMININ; LAMININ 10; LAMININ 411; LAMININ ALPHA4; LAMININ ALPHA5; LAMININ RECEPTOR; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 6;

ARTICLE; CANCER GROWTH; CELL ADHESION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MESENCHYME CELL; MOUTH CARCINOMA; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SQUAMOUS CELL CARCINOMA; UPREGULATION;

AGED; CARCINOMA, SQUAMOUS CELL; CELL DIFFERENTIATION; CELL LINE, TUMOR; DOWN-REGULATION; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LAMININ; MESENCHYMAL STEM CELLS; MOUTH NEOPLASMS; NEOPLASM INVASIVENESS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN SUBUNITS; RECEPTORS, LAMININ; TRANSCRIPTION FACTORS; UP-REGULATION;

GASTROPODA;

EID: 50249168739     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-008-0443-6     Document Type: Article

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