Identification of an active site on the laminin α5 chain globular domain that binds to CD44 and inhibits malignancy

Cancer Research

Volumn 64, Issue 14, 2004, Pages 4810-4816

  Hibino, Suguru ^a,b   Shibuya, Masahiko ^c   Engbring, Jean A ^a   Mochizuki, Mayumi ^d   Nomizu, Motoyoshi ^d   Kleinman, Hynda K ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b NIPPON MEDICAL SCHOOL   (Japan)

^c TOKYO METROPOLITAN KOMAGOME HOSPITAL   (Japan)

^d HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CELL SURFACE RECEPTOR; COLLAGEN; GLYCOSAMINOGLYCAN; GLYCOSIDASE; HERMES ANTIGEN; LAMININ; LAMININ 10; LAMININ 11; LAMININ ALPHA5; MEMBRANE PROTEIN; PROTEOGLYCAN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BINDING SITE; CANCER INHIBITION; CANCER INVASION; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LUNG METASTASIS; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; TUMOR GROWTH; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD44; BINDING SITES; CELL ADHESION; CELL DIVISION; CELL MOVEMENT; CHICK EMBRYO; GLYCOSAMINOGLYCANS; HUMANS; LAMININ; LUNG NEOPLASMS; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE;

EID: 3142742372     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-0129     Document Type: Article

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