Chondroitin sulphate modification in the α4 chain of human recombinant laminin-8 (α4β1γ1)

Matrix Biology

Volumn 21, Issue 6, 2002, Pages 483-486

  Kortesmaa, Jarkko ^a   Doi, Masayuki ^b   Patarroyo, Manuel ^c   Tryggvason, Karl ^b  

^a BioStratum AB   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Chondroitin sulphate; Laminin 8; Recombinant

Indexed keywords

CHONDROITIN SULFATE; INTEGRIN RECEPTOR; LAMININ; LAMININ 8; UNCLASSIFIED DRUG;

ABSORPTION; AMINO ACID SEQUENCE; ARTICLE; CELL ADHESION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOLECULE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PURIFICATION;

ANIMALS; CELL ADHESION; CELL LINE; CHONDROITIN SULFATES; HUMANS; INTEGRIN ALPHA6BETA1; LAMININ; MICE; PROTEIN HYBRIDIZATION; RECOMBINANT PROTEINS;

EID: 0036775810     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(02)00052-5     Document Type: Article

References (6)

1. Colognato H., Yurchenco P.D. Form and function: the laminin family of heterotrimers. Dev. Dyn. 218:2000;213-234.
2. Doi M., Thyboll J., Kortesmaa J., Jansson K., Iivanainen A., Parvardeh M., Timpl R., Hedin U., Swedenborg J., Tryggvason K. Recombinant human laminin-10: (alpha5beta1gamma1): production, purification and migration promoting activity on vascular endothelial cells. J. Biol. Chem. 277:2002;12741-12748.
3. Fujiwara H., Kikkawa Y., Sanzen N., Sekiguchi K. Purification and characterization of human laminin-8. Laminin-8 stimulates cell adhesion and migration through alpha3beta1 and alpha6beta1 integrins. J. Biol. Chem. 276:2001;17550-17558.
4. Genetics Computer Group. 2000. Program Manual for the GCG Package. Genetics Computer Group, Madison, WI.
5. Kortesmaa J., Yurchenco P., Tryggvason K. Recombinant laminin-8 (alpha(4)beta(1)gamma(1)). Production, purification,and interactions with integrins. J. Biol. Chem. 275:2000;14853-14859.
6. Sasaki T., Mann K., Timpl R. Modification of the laminin alpha 4 chain by chondroitin sulfate attachment to its N-terminal domain. FEBS Lett. 505:2001;173-178.