-
1
-
-
0036587571
-
Transforming growth factor β signal transduction
-
Dennler S, Goumans MJ, ten Dijke P. Transforming growth factor β signal transduction. J. Leukoc. Biol. 71(5), 731-740 (2002).
-
(2002)
J. Leukoc. Biol
, vol.71
, Issue.5
, pp. 731-740
-
-
Dennler, S.1
Goumans, M.J.2
ten Dijke, P.3
-
2
-
-
0031944290
-
Regulation of immune responses by TGF-β
-
Letterio JJ, Roberts AB. Regulation of immune responses by TGF-β. Annu. Rev. Immunol. 16, 137-161 (1998).
-
(1998)
Annu. Rev. Immunol
, vol.16
, pp. 137-161
-
-
Letterio, J.J.1
Roberts, A.B.2
-
3
-
-
0030427867
-
Signal transduction by members of the transforming growth factor-β superfamily
-
Attisano L, Wrana JL. Signal transduction by members of the transforming growth factor-β superfamily. Cytokine Growth Factor Rev. 7(4), 327-339 (1996).
-
(1996)
Cytokine Growth Factor Rev
, vol.7
, Issue.4
, pp. 327-339
-
-
Attisano, L.1
Wrana, J.L.2
-
4
-
-
0034574298
-
How cells read TGF-β signals
-
Massague J. How cells read TGF-β signals. Nat. Rev. Mol. Cell Biol. 1(3), 169-178 (2000).
-
(2000)
Nat. Rev. Mol. Cell Biol
, vol.1
, Issue.3
, pp. 169-178
-
-
Massague, J.1
-
5
-
-
23044466047
-
Specificity and versatility in TGF-β signaling through Smads
-
Feng XH, Derynck R. Specificity and versatility in TGF-β signaling through Smads. Annu. Rev. Cell Dev. Biol. 21, 659-693 (2005).
-
(2005)
Annu. Rev. Cell Dev. Biol
, vol.21
, pp. 659-693
-
-
Feng, X.H.1
Derynck, R.2
-
6
-
-
0029995587
-
Transforming growth factor-β1-deficient mice: Identification of isoform-specific activities in vivo
-
Letterio JJ, Roberts AB. Transforming growth factor-β1-deficient mice: identification of isoform-specific activities in vivo. J. Leukoc. Biol. 59(6), 769-774 (1996).
-
(1996)
J. Leukoc. Biol
, vol.59
, Issue.6
, pp. 769-774
-
-
Letterio, J.J.1
Roberts, A.B.2
-
7
-
-
3543109115
-
Early growth response gene 1-mediated apoptosis is essential for transforming growth factor β1-induced pulmonary fibrosis
-
Lee CG, Cho SJ, Kang MJ et al. Early growth response gene 1-mediated apoptosis is essential for transforming growth factor β1-induced pulmonary fibrosis. J. Exp. Med. 200(3), 377-389 (2004).
-
(2004)
J. Exp. Med
, vol.200
, Issue.3
, pp. 377-389
-
-
Lee, C.G.1
Cho, S.J.2
Kang, M.J.3
-
8
-
-
0005588573
-
Interstitial lung disease: A clinical overview and general approach
-
Fishman AP, Elias JA, Fishman JA et al, Eds, McGraw-Hill Inc, NY, USA
-
Raghu G. Interstitial lung disease: a clinical overview and general approach. In: Fishman's Pulmonary Diseases and Disorders. Fishman AP, Elias JA, Fishman JA et al. (Eds). McGraw-Hill Inc., NY, USA 1037-1053 (1998).
-
(1998)
Fishman's Pulmonary Diseases and Disorders
, pp. 1037-1053
-
-
Raghu, G.1
-
9
-
-
2942720573
-
The nature of small-airway obstruction in chronic obstructive pulmonary disease
-
Hogg JC, Chu F, Utokaparch S et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N. Engl. J. Med. 350(26), 2645-2653 (2004).
-
(2004)
N. Engl. J. Med
, vol.350
, Issue.26
, pp. 2645-2653
-
-
Hogg, J.C.1
Chu, F.2
Utokaparch, S.3
-
10
-
-
0037320195
-
Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease
-
Fabbri LM, Romagnoli M, Corbetta L et al. Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 167(3), 418-424 (2003).
-
(2003)
Am. J. Respir. Crit. Care Med
, vol.167
, Issue.3
, pp. 418-424
-
-
Fabbri, L.M.1
Romagnoli, M.2
Corbetta, L.3
-
11
-
-
0033739242
-
Pharmacoeconomic evaluation of COPD
-
Hilleman DE, Dewan N, Malesker M, Friedman M. Pharmacoeconomic evaluation of COPD. Chest 118(5), 1278-1285 (2000).
-
(2000)
Chest
, vol.118
, Issue.5
, pp. 1278-1285
-
-
Hilleman, D.E.1
Dewan, N.2
Malesker, M.3
Friedman, M.4
-
12
-
-
0036199723
-
The economic impact of chronic obstructive pulmonary disease
-
Faulkner MA, Hilleman DE. The economic impact of chronic obstructive pulmonary disease. Expert Opin. Pharmacother. 3(3), 219-228 (2002).
-
(2002)
Expert Opin. Pharmacother
, vol.3
, Issue.3
, pp. 219-228
-
-
Faulkner, M.A.1
Hilleman, D.E.2
-
13
-
-
0036676669
-
The burden of chronic obstructive pulmonary disease
-
Vermeire P. The burden of chronic obstructive pulmonary disease. Respir. Med. 96(Suppl. C), S3-S10 (2002).
-
(2002)
Respir. Med
, vol.96
, Issue.SUPPL. C
-
-
Vermeire, P.1
-
14
-
-
33646799069
-
Global and regional burden of disease and risk factors, 2001: Systematic analysis of population health data
-
Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 367(9524), 1747-1757 (2006).
-
(2006)
Lancet
, vol.367
, Issue.9524
, pp. 1747-1757
-
-
Lopez, A.D.1
Mathers, C.D.2
Ezzati, M.3
Jamison, D.T.4
Murray, C.J.5
-
15
-
-
34548222188
-
Global burden of COPD: Risk factors, prevalence, and future trends
-
Mannino DM, Buist AS. Global burden of COPD: risk factors, prevalence, and future trends. Lancet 370(9589), 765-773 (2007).
-
(2007)
Lancet
, vol.370
, Issue.9589
, pp. 765-773
-
-
Mannino, D.M.1
Buist, A.S.2
-
16
-
-
2942729608
-
Management of chronic obstructive pulmonary disease
-
Sutherland ER, Cherniack RM. Management of chronic obstructive pulmonary disease. N. Engl. J. Med. 350(26), 2689-2697 (2004).
-
(2004)
N. Engl. J. Med
, vol.350
, Issue.26
, pp. 2689-2697
-
-
Sutherland, E.R.1
Cherniack, R.M.2
-
17
-
-
33747835877
-
Chronic obstructive pulmonary disease: Epidemiology, pathophysiology, pathogenesis, clinical course management and rehabilitation
-
Fishman AP Ed, McGraw-Hill Inc, NY, USA
-
Senior RM. Chronic obstructive pulmonary disease: epidemiology, pathophysiology, pathogenesis, clinical course management and rehabilitation. In: Fishman's Manual of Pulmonary Diseases and Disorders. Fishman AP (Ed.). McGraw-Hill Inc., NY, USA 118-142 (2002).
-
(2002)
Fishman's Manual of Pulmonary Diseases and Disorders
, pp. 118-142
-
-
Senior, R.M.1
-
18
-
-
0001889863
-
Chronic obstructive pulmonary disease: Epidemiology, pathophysiology, and pathogenesis
-
Fishman AP, Elias JA, Fishman JA et al, Eds, McGraw-Hill Inc, NY, USA
-
Senior RM, Shapiro SD. Chronic obstructive pulmonary disease: epidemiology, pathophysiology, and pathogenesis. In: Fishman's Pulmonary Diseases and Disorders. Fishman AP, Elias JA, Fishman JA et al. (Eds). McGraw-Hill Inc., NY, USA 659-681 (1998).
-
(1998)
Fishman's Pulmonary Diseases and Disorders
, pp. 659-681
-
-
Senior, R.M.1
Shapiro, S.D.2
-
20
-
-
0032749366
-
Airway remodeling in asthma
-
Elias JA, Zhu Z, Chupp G, Homer RJ. Airway remodeling in asthma. J. Clin. Invest. 104(8), 1001-1006 (1999).
-
(1999)
J. Clin. Invest
, vol.104
, Issue.8
, pp. 1001-1006
-
-
Elias, J.A.1
Zhu, Z.2
Chupp, G.3
Homer, R.J.4
-
21
-
-
0033968434
-
Apoptosis and formation of peroxynitrite in the lungs of patients with obliterative bronchiolitis
-
Hansen PR, Holm AM, Svendseri UG, Olsen PS, Andersen CB. Apoptosis and formation of peroxynitrite in the lungs of patients with obliterative bronchiolitis. J. Heart Lung Transplant. 19(2), 160-166 (2000).
-
(2000)
J. Heart Lung Transplant
, vol.19
, Issue.2
, pp. 160-166
-
-
Hansen, P.R.1
Holm, A.M.2
Svendseri, U.G.3
Olsen, P.S.4
Andersen, C.B.5
-
22
-
-
0033406743
-
Cellular and connective tissue changes in alveolar septal walls in emphysema
-
Vlahovic G, Russell ML, Mercer RR, Crapo JD. Cellular and connective tissue changes in alveolar septal walls in emphysema. Am. J. Respir. Crit. Care Med. 160(6), 2086-2092 (1999).
-
(1999)
Am. J. Respir. Crit. Care Med
, vol.160
, Issue.6
, pp. 2086-2092
-
-
Vlahovic, G.1
Russell, M.L.2
Mercer, R.R.3
Crapo, J.D.4
-
23
-
-
0038465920
-
Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade
-
Tuder RM, Zhen L, Cho CY et al. Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade. Am. J. Respir. Cell Mol. Biol. 29(1), 88-97 (2003).
-
(2003)
Am. J. Respir. Cell Mol. Biol
, vol.29
, Issue.1
, pp. 88-97
-
-
Tuder, R.M.1
Zhen, L.2
Cho, C.Y.3
-
24
-
-
0034474704
-
Is oxidative stress central to the pathogenesis of chronic obstructive pulmonary disease?
-
MacNee W, Rahman I. Is oxidative stress central to the pathogenesis of chronic obstructive pulmonary disease? Trends Mol. Med. 7(2), 55-62 (2001).
-
(2001)
Trends Mol. Med
, vol.7
, Issue.2
, pp. 55-62
-
-
MacNee, W.1
Rahman, I.2
-
25
-
-
0033660171
-
Inhibition of VEGF receptors causes lung cell apoptosis and emphysema
-
Kasahara Y, Tuder RM, Taraseviciene-Stewart L et al. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J. Clin. Invest. 106(11), 1311-1319 (2000).
-
(2000)
J. Clin. Invest
, vol.106
, Issue.11
, pp. 1311-1319
-
-
Kasahara, Y.1
Tuder, R.M.2
Taraseviciene-Stewart, L.3
-
26
-
-
0035077330
-
Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema
-
Kasahara Y, Tuder RM, Cool CD et al. Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am. J. Respir. Crit. Care Med. 163(3 Pt 1), 737-744 (2001).
-
(2001)
Am. J. Respir. Crit. Care Med
, vol.163
, Issue.3 PART 1
, pp. 737-744
-
-
Kasahara, Y.1
Tuder, R.M.2
Cool, C.D.3
-
27
-
-
0038070219
-
Alveolar wall apoptosis causes lung destruction and emphysematous changes
-
Aoshiba K, Yokohori N, Nagai A. Alveolar wall apoptosis causes lung destruction and emphysematous changes. Am. J. Respir. Cell Mol. Biol. 28(5), 555-562 (2003).
-
(2003)
Am. J. Respir. Cell Mol. Biol
, vol.28
, Issue.5
, pp. 555-562
-
-
Aoshiba, K.1
Yokohori, N.2
Nagai, A.3
-
28
-
-
0034949094
-
Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema
-
Majo J, Ghezzo H, Cosio MG. Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema. Eur. Respir. J. 17(5), 946-953 (2001).
-
(2001)
Eur. Respir. J
, vol.17
, Issue.5
, pp. 946-953
-
-
Majo, J.1
Ghezzo, H.2
Cosio, M.G.3
-
29
-
-
0034101866
-
Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD
-
Segura-Valdez L, Pardo A, Gaxiola M et al. Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD. Chest 117(3), 684-694 (2000).
-
(2000)
Chest
, vol.117
, Issue.3
, pp. 684-694
-
-
Segura-Valdez, L.1
Pardo, A.2
Gaxiola, M.3
-
30
-
-
1242306658
-
Increased levels of cell death and proliferation in alveolar wall cells in patients with pulmonary emphysema
-
Yokohori N, Aoshiba K, Nagai A. Increased levels of cell death and proliferation in alveolar wall cells in patients with pulmonary emphysema. Chest 125(2), 626-632 (2004).
-
(2004)
Chest
, vol.125
, Issue.2
, pp. 626-632
-
-
Yokohori, N.1
Aoshiba, K.2
Nagai, A.3
-
31
-
-
0038070232
-
Apoptosis and emphysema: The missing link
-
Tuder RM, Petrache I, Elias JA, Voelkel NF, Henson PM. Apoptosis and emphysema: the missing link. Am. J. Respir. Cell Mol. Biol. 28(5), 551-554 (2003).
-
(2003)
Am. J. Respir. Cell Mol. Biol
, vol.28
, Issue.5
, pp. 551-554
-
-
Tuder, R.M.1
Petrache, I.2
Elias, J.A.3
Voelkel, N.F.4
Henson, P.M.5
-
32
-
-
20444368841
-
Role of cathepsin S-depenaent epithelial cell apoptosis in γ interferon-induced alveolar remodeling and pulmonary emphysema
-
In Press
-
Zheng T, Kang MJ, Crothers K et al. Role of cathepsin S-depenaent epithelial cell apoptosis in γ interferon-induced alveolar remodeling and pulmonary emphysema. J. Immunol. (2005) (In Press).
-
(2005)
J. Immunol
-
-
Zheng, T.1
Kang, M.J.2
Crothers, K.3
-
33
-
-
17044453955
-
Increased expression of transforming growth factor-β1 in small airway epithelium from tobacco smokers and patients with chronic obstructive pulmonary disease (COPD)
-
Takizawa H, Tanaka M, Takami K et al. Increased expression of transforming growth factor-β1 in small airway epithelium from tobacco smokers and patients with chronic obstructive pulmonary disease (COPD). Am. J. Respir. Crit. Care Med. 163(6), 1476-1483 (2001).
-
(2001)
Am. J. Respir. Crit. Care Med
, vol.163
, Issue.6
, pp. 1476-1483
-
-
Takizawa, H.1
Tanaka, M.2
Takami, K.3
-
34
-
-
0346726049
-
Expression of transforming growth factor β1 in bronchial biopsies in asthma and COPD
-
Kokturk N, Tatlicioglu T, Memis L, Akyurek N, Akyol G. Expression of transforming growth factor β1 in bronchial biopsies in asthma and COPD. J. Asthma 40(8), 887-893 (2003).
-
(2003)
J. Asthma
, vol.40
, Issue.8
, pp. 887-893
-
-
Kokturk, N.1
Tatlicioglu, T.2
Memis, L.3
Akyurek, N.4
Akyol, G.5
-
35
-
-
0037373277
-
Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome
-
Neptune ER, Frischmeyer PA, Arking DE et al. Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome. Nat. Genet. 33(3), 407-411 (2003).
-
(2003)
Nat. Genet
, vol.33
, Issue.3
, pp. 407-411
-
-
Neptune, E.R.1
Frischmeyer, P.A.2
Arking, D.E.3
-
36
-
-
4344653389
-
SMAD-signaling in chronic obstructive pulmonary disease: Transcriptional down-regulation of inhibitory SMAD 6 and 7 by cigarette smoke
-
Springer J, Scholz FR, Peiser C, Groneberg DA, Fischer A. SMAD-signaling in chronic obstructive pulmonary disease: transcriptional down-regulation of inhibitory SMAD 6 and 7 by cigarette smoke. Biol. Chem. 385(7), 649-653 (2004).
-
(2004)
Biol. Chem
, vol.385
, Issue.7
, pp. 649-653
-
-
Springer, J.1
Scholz, F.R.2
Peiser, C.3
Groneberg, D.A.4
Fischer, A.5
-
37
-
-
0037435009
-
Loss of integrin α(v)β6-mediated TGF-β activation causes MMP12-dependent emphysema
-
Morris DG, Huang X, Kaminski N et al. Loss of integrin α(v)β6-mediated TGF-β activation causes MMP12-dependent emphysema. Nature 422(6928), 169-173 (2003).
-
(2003)
Nature
, vol.422
, Issue.6928
, pp. 169-173
-
-
Morris, D.G.1
Huang, X.2
Kaminski, N.3
-
38
-
-
3242799550
-
Smad3 null mice develop airspace enlargement and are resistant to TGF-β-mediated pulmonary fibrosis
-
Bonniaud P, Kolb M, Galt T et al. Smad3 null mice develop airspace enlargement and are resistant to TGF-β-mediated pulmonary fibrosis. J. Immunol. 173(3), 2099-2108 (2004).
-
(2004)
J. Immunol
, vol.173
, Issue.3
, pp. 2099-2108
-
-
Bonniaud, P.1
Kolb, M.2
Galt, T.3
-
39
-
-
1242329185
-
Transforming growth factor-β1 genotype and susceptibility to chronic obstructive pulmonary disease
-
Wu L, Chau J, Young RP et al. Transforming growth factor-β1 genotype and susceptibility to chronic obstructive pulmonary disease. Thorax 59 (2), 126-129 (2004).
-
(2004)
Thorax
, vol.59
, Issue.2
, pp. 126-129
-
-
Wu, L.1
Chau, J.2
Young, R.P.3
-
40
-
-
34249057411
-
Semaphorin 7A plays a critical role in TGF-β1-induced pulmonary fibrosis
-
Kang HR, Lee CG, Homer RJ, Elias JA. Semaphorin 7A plays a critical role in TGF-β1-induced pulmonary fibrosis. J. Exp. Med. 204(5), 1083-1093 (2007).
-
(2007)
J. Exp. Med
, vol.204
, Issue.5
, pp. 1083-1093
-
-
Kang, H.R.1
Lee, C.G.2
Homer, R.J.3
Elias, J.A.4
-
41
-
-
34147099468
-
Transforming growth factor (TGF)-β1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12
-
Kang HR, Cho SJ, Lee CG, Homer RJ, Elias JA. Transforming growth factor (TGF)-β1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12. J. Biol. Chem. 282(10), 7723-7732 (2007).
-
(2007)
J. Biol. Chem
, vol.282
, Issue.10
, pp. 7723-7732
-
-
Kang, H.R.1
Cho, S.J.2
Lee, C.G.3
Homer, R.J.4
Elias, J.A.5
-
42
-
-
40649126575
-
P21 regulates TGF-β1-induced pulmonary responses via a TNF-α-signaling pathway
-
Yamasaki M, Kang HR, Homer RJ et al. P21 regulates TGF-β1-induced pulmonary responses via a TNF-α-signaling pathway. Am. J. Respir. Cell Mol. Biol. 38(3), 346-353 (2008).
-
(2008)
Am. J. Respir. Cell Mol. Biol
, vol.38
, Issue.3
, pp. 346-353
-
-
Yamasaki, M.1
Kang, H.R.2
Homer, R.J.3
-
43
-
-
0036936550
-
Roles for insulin-like growth factor I and transforming growth factor-β in fibrotic lung disease
-
Krein PM, Winston BW. Roles for insulin-like growth factor I and transforming growth factor-β in fibrotic lung disease. Chest 122(6 Suppl.), 289S-293S (2002).
-
(2002)
Chest
, vol.122
, Issue.6 SUPPL.
-
-
Krein, P.M.1
Winston, B.W.2
-
44
-
-
0035895243
-
Idiopathic pulmonary fibrosis: Prevailing and evolving hypotheses about its pathogenesis and implications for therapy
-
Selman M, King TE, Pardo A. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann. Intern. Med. 134(2), 136-151 (2001).
-
(2001)
Ann. Intern. Med
, vol.134
, Issue.2
, pp. 136-151
-
-
Selman, M.1
King, T.E.2
Pardo, A.3
-
45
-
-
0030076509
-
TGF-β 1, but not TGF-β 2 or TGF-β 3, is differentially present in epithelial cells of advanced pulmonary fibrosis: An immunohistochemical study
-
Khalil N, O'Connor RN, Flanders KC, Unruh H. TGF-β 1, but not TGF-β 2 or TGF-β 3, is differentially present in epithelial cells of advanced pulmonary fibrosis: an immunohistochemical study. Am. J. Respir. Cell Mol. Biol. 14(2), 131-138 (1996).
-
(1996)
Am. J. Respir. Cell Mol. Biol
, vol.14
, Issue.2
, pp. 131-138
-
-
Khalil, N.1
O'Connor, R.N.2
Flanders, K.C.3
Unruh, H.4
-
46
-
-
0035181092
-
Regulation of the effects of TGF-β 1 by activation of latent TGF-β 1 and differential expression of TGF-β receptors (T β R-I and T β R-II) in idiopathic pulmonary fibrosis
-
Khalil N, Parekh TV, O'Connor R et al. Regulation of the effects of TGF-β 1 by activation of latent TGF-β 1 and differential expression of TGF-β receptors (T β R-I and T β R-II) in idiopathic pulmonary fibrosis. Thorax 56(12), 907-915 (2001).
-
(2001)
Thorax
, vol.56
, Issue.12
, pp. 907-915
-
-
Khalil, N.1
Parekh, T.V.2
O'Connor, R.3
-
47
-
-
0041677660
-
Release of biologically active TGF-(β) 1 by alveolar epithelial cells results in pulmonary fibrosis
-
In press
-
Xu YD, Hua J, Mui A et al. Release of biologically active TGF-(β) 1 by alveolar epithelial cells results in pulmonary fibrosis. Am. J. Physiol. (Lung Cell Mol. Physiol.) (2003) (In press).
-
(2003)
Am. J. Physiol. (Lung Cell Mol. Physiol.)
-
-
Xu, Y.D.1
Hua, J.2
Mui, A.3
-
48
-
-
0033844731
-
A CD36 synthetic peptide inhibits bleomycin-induced pulmonary inflammation and connective tissue synthesis in the rat
-
Yehualaeshet T, O'Connor R, Begleiter A et al. A CD36 synthetic peptide inhibits bleomycin-induced pulmonary inflammation and connective tissue synthesis in the rat. Am. J. Respir. Cell Mol. Biol. 23(2), 204-212 (2000).
-
(2000)
Am. J. Respir. Cell Mol. Biol
, vol.23
, Issue.2
, pp. 204-212
-
-
Yehualaeshet, T.1
O'Connor, R.2
Begleiter, A.3
-
49
-
-
0032719815
-
Transient gene transfer and expression of Smad7 prevents bleomycin-induccd lung fibrosis in mice
-
Nakao A, Fujii M, Matsumura R et al. Transient gene transfer and expression of Smad7 prevents bleomycin-induccd lung fibrosis in mice. J. Clin. Invest. 104(1), 5-11 (1999).
-
(1999)
J. Clin. Invest
, vol.104
, Issue.1
, pp. 5-11
-
-
Nakao, A.1
Fujii, M.2
Matsumura, R.3
-
50
-
-
0030800795
-
Adenovector-mediated gene transfer of active transforming growth factor-β1 induces prolonged severe fibrosis in rat lung
-
Sime PJ, Xing Z, Graham FL, Csaky KG, Gauldie J. Adenovector-mediated gene transfer of active transforming growth factor-β1 induces prolonged severe fibrosis in rat lung. J. Clin. Invest. 100(4), 768-776 (1997).
-
(1997)
J. Clin. Invest
, vol.100
, Issue.4
, pp. 768-776
-
-
Sime, P.J.1
Xing, Z.2
Graham, F.L.3
Csaky, K.G.4
Gauldie, J.5
-
51
-
-
0037241857
-
Re-evaluation of fibrogenic cytokines in lung fibrosis
-
Kelly M, Kolb M, Bonniaud P, Gauldie J. Re-evaluation of fibrogenic cytokines in lung fibrosis. Curr. Pharm. Des. 9(1), 39-49 (2003).
-
(2003)
Curr. Pharm. Des
, vol.9
, Issue.1
, pp. 39-49
-
-
Kelly, M.1
Kolb, M.2
Bonniaud, P.3
Gauldie, J.4
-
52
-
-
0036335052
-
Increased circulating levels of soluble Fas ligand are correlated with disease activity in patients with fibrosing lung diseases
-
Kuwano Y, Maeyama T, Inoshima I et al. Increased circulating levels of soluble Fas ligand are correlated with disease activity in patients with fibrosing lung diseases. Respirology 7(1), 15-21 (2002).
-
(2002)
Respirology
, vol.7
, Issue.1
, pp. 15-21
-
-
Kuwano, Y.1
Maeyama, T.2
Inoshima, I.3
-
53
-
-
0032622244
-
The involvement of Fas-Fas ligand pathway in fibrosing lung diseases
-
Kuwano K, Miyazaki H, Hagimoto N et al. The involvement of Fas-Fas ligand pathway in fibrosing lung diseases. Am. J. Respir. Cell Mol. Biol. 20(1), 53-60 (1999).
-
(1999)
Am. J. Respir. Cell Mol. Biol
, vol.20
, Issue.1
, pp. 53-60
-
-
Kuwano, K.1
Miyazaki, H.2
Hagimoto, N.3
-
54
-
-
0030215822
-
P21 Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis
-
Kuwano K, Kunitake R, Kawasaki M et al. P21 Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 154(2 Pt 1), 477-483 (1996).
-
(1996)
Am. J. Respir. Crit. Care Med
, vol.154
, Issue.2 PART 1
, pp. 477-483
-
-
Kuwano, K.1
Kunitake, R.2
Kawasaki, M.3
-
55
-
-
0032717522
-
Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis
-
Kuwano K, Hagimoto N, Kawasaki M et al. Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis. J. Clin. Invest. 104(1), 13-19 (1999).
-
(1999)
J. Clin. Invest
, vol.104
, Issue.1
, pp. 13-19
-
-
Kuwano, K.1
Hagimoto, N.2
Kawasaki, M.3
-
56
-
-
0036231985
-
Transforming growth factor-β1: Its anti-inflammatory and pro-fibrotic effects
-
Ling E, Robinson DS. Transforming growth factor-β1: its anti-inflammatory and pro-fibrotic effects. Clin. Exp. Allergy 32(2), 175-178 (2002).
-
(2002)
Clin. Exp. Allergy
, vol.32
, Issue.2
, pp. 175-178
-
-
Ling, E.1
Robinson, D.S.2
-
57
-
-
0036124599
-
Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation
-
Flanders KC, Sullivan CD, Fujii M et al. Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation. Am. J. Pathol. 160(3), 1057-1068 (2002).
-
(2002)
Am. J. Pathol
, vol.160
, Issue.3
, pp. 1057-1068
-
-
Flanders, K.C.1
Sullivan, C.D.2
Fujii, M.3
-
58
-
-
0035501062
-
TGF-β signaling in cancer - a double-edged sword
-
Akhurst RJ, Derynck R. TGF-β signaling in cancer - a double-edged sword. Trends Cell Biol. 11 (11), S44-S51 (2001).
-
(2001)
Trends Cell Biol
, vol.11
, Issue.11
-
-
Akhurst, R.J.1
Derynck, R.2
-
59
-
-
0034927240
-
Is Smad3 a major player in signal transduction pathways leading to fibrogenesis?
-
Roberts AB, Piek E, Bottinger EP et al. Is Smad3 a major player in signal transduction pathways leading to fibrogenesis? Chest 120(1 Suppl.), 43S-47S (2001).
-
(2001)
Chest
, vol.120
, Issue.1 SUPPL.
-
-
Roberts, A.B.1
Piek, E.2
Bottinger, E.P.3
-
60
-
-
0026751479
-
Differential effect of transforming growth factor β on the synthesis of Th1- and Th2-like lymphokines by human T lymphocytes
-
Fargeas C, Wu CY, Nakajima T et al. Differential effect of transforming growth factor β on the synthesis of Th1- and Th2-like lymphokines by human T lymphocytes. Eur. J. Immunol. 22(8), 2173-2176 (1992).
-
(1992)
Eur. J. Immunol
, vol.22
, Issue.8
, pp. 2173-2176
-
-
Fargeas, C.1
Wu, C.Y.2
Nakajima, T.3
-
61
-
-
0029149596
-
Control of CD4 effector fate: Transforming growth factor β1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion
-
Zhang X, Giangreco L, Broome HE, Dargan CM, Swain SL. Control of CD4 effector fate: transforming growth factor β1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion. J. Exp. Med. 182(3), 699-709 (1995).
-
(1995)
J. Exp. Med
, vol.182
, Issue.3
, pp. 699-709
-
-
Zhang, X.1
Giangreco, L.2
Broome, H.E.3
Dargan, C.M.4
Swain, S.L.5
-
62
-
-
0035903306
-
Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor β(1)
-
Lee CG, Homer RJ, Zhu Z et al. Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor β(1). J. Exp. Med. 194(6), 809-821 (2001).
-
(2001)
J. Exp. Med
, vol.194
, Issue.6
, pp. 809-821
-
-
Lee, C.G.1
Homer, R.J.2
Zhu, Z.3
-
63
-
-
0034178260
-
TGF-β1 and radiation fibrosis: A master switch and a specific therapeutic target?
-
Martin M, Lefaix J, Delanian S. TGF-β1 and radiation fibrosis: a master switch and a specific therapeutic target? Int. J. Radiat. Oncol. Biol. Phys. 47(2), 277-290 (2000).
-
(2000)
Int. J. Radiat. Oncol. Biol. Phys
, vol.47
, Issue.2
, pp. 277-290
-
-
Martin, M.1
Lefaix, J.2
Delanian, S.3
-
65
-
-
0034977190
-
TGF-β is a critical mediator of acute lung injury
-
Pittet JF, Griffiths MJ, Geiser T et al. TGF-β is a critical mediator of acute lung injury. J. Clin. Invest. 107(12), 1537-1544 (2001).
-
(2001)
J. Clin. Invest
, vol.107
, Issue.12
, pp. 1537-1544
-
-
Pittet, J.F.1
Griffiths, M.J.2
Geiser, T.3
-
66
-
-
0035701641
-
Negative effect of transforming growth factor-β-1 on intestinal anastomotic tissue regeneration
-
Fukuda H, Motohiro T, Nakai K et al. Negative effect of transforming growth factor-β-1 on intestinal anastomotic tissue regeneration. Eur. Surg. Res. 33(5-6), 388-394 (2001).
-
(2001)
Eur. Surg. Res
, vol.33
, Issue.5-6
, pp. 388-394
-
-
Fukuda, H.1
Motohiro, T.2
Nakai, K.3
-
67
-
-
0036317623
-
Development, characterization, and wound healing of the keratin 14 promoted transforming growth factor-β1 transgenic mouse
-
Chan T, Ghahary A, Demare J et al. Development, characterization, and wound healing of the keratin 14 promoted transforming growth factor-β1 transgenic mouse. Wound Repair Regen. 10(3), 177-187 (2002).
-
(2002)
Wound Repair Regen
, vol.10
, Issue.3
, pp. 177-187
-
-
Chan, T.1
Ghahary, A.2
Demare, J.3
-
68
-
-
0037092499
-
Resistance of keratinocytes to TGFβ-mediated growth restriction and apoptosis induction accelerates re-epithelialization in skin wounds
-
Amendt C, Mann A, Schirmacher P, Blessing M. Resistance of keratinocytes to TGFβ-mediated growth restriction and apoptosis induction accelerates re-epithelialization in skin wounds. J. Cell Sci. 115(Pt 10), 2189-2198 (2002).
-
(2002)
J. Cell Sci
, vol.115
, Issue.PART 10
, pp. 2189-2198
-
-
Amendt, C.1
Mann, A.2
Schirmacher, P.3
Blessing, M.4
-
69
-
-
3543107212
-
Fibrotic disease and the T(H) 1/T(H) 2 paradigm
-
Wynn TA. Fibrotic disease and the T(H) 1/T(H) 2 paradigm. Nat. Rev. Immunol. 4(8), 583-594 (2004).
-
(2004)
Nat. Rev. Immunol
, vol.4
, Issue.8
, pp. 583-594
-
-
Wynn, T.A.1
-
70
-
-
4644225081
-
IL-13 activates a mechanism of tissue fibrosis that is completely TGF-β independent
-
Kaviratne M, Hesse M, Leusink M et al. IL-13 activates a mechanism of tissue fibrosis that is completely TGF-β independent. J. Immunol. 173(6), 4020-4029 (2004).
-
(2004)
J. Immunol
, vol.173
, Issue.6
, pp. 4020-4029
-
-
Kaviratne, M.1
Hesse, M.2
Leusink, M.3
-
71
-
-
2342482002
-
Nitric oxide in health and disease of the respiratory system
-
Ricciardolo FL, Sterk PJ, Gaston B, Folkerts G. Nitric oxide in health and disease of the respiratory system. Physiol. Rev. 84(3), 731-765 (2004).
-
(2004)
Physiol. Rev
, vol.84
, Issue.3
, pp. 731-765
-
-
Ricciardolo, F.L.1
Sterk, P.J.2
Gaston, B.3
Folkerts, G.4
-
72
-
-
7044229899
-
The development of emphysema in cigarette smoke exposed mice is strain dependent
-
Guerassimov A, Hoshino Y, Takubo Y et al. The development of emphysema in cigarette smoke exposed mice is strain dependent. Am. J. Respir. Crit. Care Med. 170(9), 974-980 (2004).
-
(2004)
Am. J. Respir. Crit. Care Med
, vol.170
, Issue.9
, pp. 974-980
-
-
Guerassimov, A.1
Hoshino, Y.2
Takubo, Y.3
-
73
-
-
0035984567
-
Differences in the fibrogenic response after transfer of active transforming growth factor-β1 gene to lungs of 'fibrosis-prone' and 'fibrosis-resistant' mouse strains
-
Kolb M, Bonniaud P, Galt T et al. Differences in the fibrogenic response after transfer of active transforming growth factor-β1 gene to lungs of 'fibrosis-prone' and 'fibrosis-resistant' mouse strains. Am. J. Respir. Cell Mol. Biol. 27(2), 141-150 (2002).
-
(2002)
Am. J. Respir. Cell Mol. Biol
, vol.27
, Issue.2
, pp. 141-150
-
-
Kolb, M.1
Bonniaud, P.2
Galt, T.3
-
74
-
-
0029895964
-
Inheritance of susceptibility to bleomycin-induced pulmonary fibrosis in the mouse
-
Haston CK, Amos CI, King TM, Travis EL. Inheritance of susceptibility to bleomycin-induced pulmonary fibrosis in the mouse. Cancer Res. 56(11), 2596-2601 (1996).
-
(1996)
Cancer Res
, vol.56
, Issue.11
, pp. 2596-2601
-
-
Haston, C.K.1
Amos, C.I.2
King, T.M.3
Travis, E.L.4
-
75
-
-
0036667985
-
Bleomycin hydrolase and a genetic locus within the MHC affect risk for pulmonary fibrosis in mice
-
Haston CK, Wang M, Dejournett RE et al. Bleomycin hydrolase and a genetic locus within the MHC affect risk for pulmonary fibrosis in mice. Hum. Mol. Genet. 11(16), 1855-1863 (2002).
-
(2002)
Hum. Mol. Genet
, vol.11
, Issue.16
, pp. 1855-1863
-
-
Haston, C.K.1
Wang, M.2
Dejournett, R.E.3
-
76
-
-
0036645068
-
Universal and fadiation-specific loci influence murine susceptibility to radiation-induced pulmonary fibrosis
-
Haston CK, Zhou X, Gumbiner-Russo L et al. Universal and fadiation-specific loci influence murine susceptibility to radiation-induced pulmonary fibrosis. Cancer Res. 62(13), 3782-3788 (2002).
-
(2002)
Cancer Res
, vol.62
, Issue.13
, pp. 3782-3788
-
-
Haston, C.K.1
Zhou, X.2
Gumbiner-Russo, L.3
-
77
-
-
18744434746
-
Mapping susceptibility genes for the induction of pulmonary fibrosis in mice
-
Barth RK, Hanchett LA, Baecher-Allan CM. Mapping susceptibility genes for the induction of pulmonary fibrosis in mice. Chest 121 (3 Suppl.), 21S (2002).
-
(2002)
Chest
, vol.121
, Issue.3 SUPPL.
-
-
Barth, R.K.1
Hanchett, L.A.2
Baecher-Allan, C.M.3
-
78
-
-
0019945992
-
Lung fibrosis and emphysema: Divergent responses to a common injury?
-
Niewoehner DE, Hoidal JR. Lung fibrosis and emphysema: divergent responses to a common injury? Science 217(4557), 359-360 (1982).
-
(1982)
Science
, vol.217
, Issue.4557
, pp. 359-360
-
-
Niewoehner, D.E.1
Hoidal, J.R.2
-
80
-
-
0037097680
-
TGF-β 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells
-
Hagimoto N, Kuwano Y, Inoshima I et al. TGF-β 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells. J. Immunol. 168(12), 6470-6478 (2002).
-
(2002)
J. Immunol
, vol.168
, Issue.12
, pp. 6470-6478
-
-
Hagimoto, N.1
Kuwano, Y.2
Inoshima, I.3
-
81
-
-
34447116385
-
The regulatory role of TGF-β in airway remodeling in asthma
-
Makinde T, Murphy RF, Agrawal DK. The regulatory role of TGF-β in airway remodeling in asthma. Immunol. Cell Biol. 85(5), 348-356 (2007).
-
(2007)
Immunol. Cell Biol
, vol.85
, Issue.5
, pp. 348-356
-
-
Makinde, T.1
Murphy, R.F.2
Agrawal, D.K.3
-
83
-
-
33847040423
-
Gene transfer ofhepatocyte growth factor by electroporation reduces bleomycin-induced lung fibrosis
-
Gazdhar A, Fachinger P, van Leer C et al. Gene transfer ofhepatocyte growth factor by electroporation reduces bleomycin-induced lung fibrosis. Am. J Physiol. Lung Cell. Mol. Physiol. 292(2), L529-L536 (2007).
-
(2007)
Am. J Physiol. Lung Cell. Mol. Physiol
, vol.292
, Issue.2
-
-
Gazdhar, A.1
Fachinger, P.2
van Leer, C.3
-
84
-
-
33745472563
-
Defect of pro-hepatocyte growth factor activation by fibroblasts in idiopathic pulmonary fibrosis
-
Marchand-Adam S, Fabre A, Mailleux AA et al. Defect of pro-hepatocyte growth factor activation by fibroblasts in idiopathic pulmonary fibrosis. Am J. Respir. Crit. Care Med. 174(1), 58-66 (2006).
-
(2006)
Am J. Respir. Crit. Care Med
, vol.174
, Issue.1
, pp. 58-66
-
-
Marchand-Adam, S.1
Fabre, A.2
Mailleux, A.A.3
-
85
-
-
33745860364
-
Transgenic modeling of transforming growth factor-β(1): Role of apoptosis in fibrosis and alveolar remodeling
-
Lee CG, Kang HR, Homer RJ, Chupp, G, Elias JA. Transgenic modeling of transforming growth factor-β(1): role of apoptosis in fibrosis and alveolar remodeling. Proc. Am. Thorac Soc. 3(5), 418-423 (2006).
-
(2006)
Proc. Am. Thorac Soc
, vol.3
, Issue.5
, pp. 418-423
-
-
Lee, C.G.1
Kang, H.R.2
Homer, R.J.3
Chupp, G.4
Elias, J.A.5
-
86
-
-
34248389630
-
Effect of an angiotensin II receptor blocker and two angiotensin converting enzyme inhibitors on transforming growth factor-β (TGF-β) and α-actomyosin (α SMA), important mediators of radiation-induced pneumopathy and lung fibrosis
-
Molteni A, Wolfe LF, Ward WF et al. Effect of an angiotensin II receptor blocker and two angiotensin converting enzyme inhibitors on transforming growth factor-β (TGF-β) and α-actomyosin (α SMA), important mediators of radiation-induced pneumopathy and lung fibrosis. Curr. Pharm. Des. 13(13), 1307-1316 (2007).
-
(2007)
Curr. Pharm. Des
, vol.13
, Issue.13
, pp. 1307-1316
-
-
Molteni, A.1
Wolfe, L.F.2
Ward, W.F.3
-
87
-
-
33751207110
-
VEGF, a prosurvival factor, acts in concert with TGF-β1 to induce endothelial cell apoptosis
-
Ferrari G, Pintucci G, Seghezzi G et al. VEGF, a prosurvival factor, acts in concert with TGF-β1 to induce endothelial cell apoptosis. Proc. Natl Acad. Sci. USA 103(46), 17260-17265 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.46
, pp. 17260-17265
-
-
Ferrari, G.1
Pintucci, G.2
Seghezzi, G.3
-
88
-
-
39549091069
-
VEGF and TGF-β are required for the maintenance of the choroid plexus and ependyma
-
Maharaj AS, Wilshe TE, Saint-Geniez M et al. VEGF and TGF-β are required for the maintenance of the choroid plexus and ependyma. J. Exp. Med. 205(2), 491-501 (2008).
-
(2008)
J. Exp. Med
, vol.205
, Issue.2
, pp. 491-501
-
-
Maharaj, A.S.1
Wilshe, T.E.2
Saint-Geniez, M.3
-
89
-
-
41049094560
-
Endoglin in angiogenesis and vascular diseases
-
Ten Dijke P, Goumans MJ, Pardali E. Endoglin in angiogenesis and vascular diseases. Angiogenesis 11 (1), 79-89 (2008).
-
(2008)
Angiogenesis
, vol.11
, Issue.1
, pp. 79-89
-
-
Ten Dijke, P.1
Goumans, M.J.2
Pardali, E.3
-
90
-
-
38549159026
-
Cellular and molecular mechanisms of fibrosis
-
Wynn TA. Cellular and molecular mechanisms of fibrosis. J. Pathol. 214(2), 199-210 (2008).
-
(2008)
J. Pathol
, vol.214
, Issue.2
, pp. 199-210
-
-
Wynn, T.A.1
-
91
-
-
0037314229
-
New insights into the pathogenesis of asthma
-
Elias JA, Lee CG, Zheng T et al. New insights into the pathogenesis of asthma. J. Clin. Invest. 111(3), 291-297 (2003).
-
(2003)
J. Clin. Invest
, vol.111
, Issue.3
, pp. 291-297
-
-
Elias, J.A.1
Lee, C.G.2
Zheng, T.3
-
92
-
-
13344275780
-
Fighting pulmonary fibrosis: New science brings new therapeutic opptunities
-
Das A, Griswold D, Molloy C, Protter A, Laurent G. Fighting pulmonary fibrosis: new science brings new therapeutic opptunities. Drug Discov. Today Ther. Strateg. 1(3), 361-368 (2004).
-
(2004)
Drug Discov. Today Ther. Strateg
, vol.1
, Issue.3
, pp. 361-368
-
-
Das, A.1
Griswold, D.2
Molloy, C.3
Protter, A.4
Laurent, G.5
-
93
-
-
33646914221
-
The role of circulating fibrocytes in fibrosis
-
Quan TE, Cowper SE, Bucala R. The role of circulating fibrocytes in fibrosis. Curr. Rheumatol. Rep. 8(2), 145-150 (2006).
-
(2006)
Curr. Rheumatol. Rep
, vol.8
, Issue.2
, pp. 145-150
-
-
Quan, T.E.1
Cowper, S.E.2
Bucala, R.3
-
94
-
-
34547960749
-
The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibroses
-
Bellini A, Mattoli S. The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibroses. Lab. Invest. 87(9), 858-870 (2007).
-
(2007)
Lab. Invest
, vol.87
, Issue.9
, pp. 858-870
-
-
Bellini, A.1
Mattoli, S.2
-
95
-
-
0038544594
-
Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma
-
Schmidt M, Sun G, Stacey MA, Mori L, Mattoli S. Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma. J. Immunol. 171(1), 380-389 (2003).
-
(2003)
J. Immunol
, vol.171
, Issue.1
, pp. 380-389
-
-
Schmidt, M.1
Sun, G.2
Stacey, M.A.3
Mori, L.4
Mattoli, S.5
-
96
-
-
22144461325
-
-
Nawshad A, Lagamba D, Polad A, Hay ED. Transforming growth factor-β signaling during epithelial-mesenchymal transformation: implications for embryogenesis and tumor metastasis. Cells Tissues Organs 1790-2, 11-23 (2005).
-
Nawshad A, Lagamba D, Polad A, Hay ED. Transforming growth factor-β signaling during epithelial-mesenchymal transformation: implications for embryogenesis and tumor metastasis. Cells Tissues Organs 1790-2), 11-23 (2005).
-
-
-
-
97
-
-
33748375828
-
Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix
-
Kim KK, Kugler MC, Wolters PJ et al. Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc. Natl Acad. Sci. USA 103(35), 13180-13185 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.35
, pp. 13180-13185
-
-
Kim, K.K.1
Kugler, M.C.2
Wolters, P.J.3
-
98
-
-
34548411746
-
TGF-β-induced EMT: Mechanisms and implications for fibrotic lung disease
-
Willis BC, Borok Z. TGF-β-induced EMT: mechanisms and implications for fibrotic lung disease. Am. J. Physiol Lung Cell. Mol. Physiol. 293(3), L525-534 (2007).
-
(2007)
Am. J. Physiol Lung Cell. Mol. Physiol
, vol.293
, Issue.3
-
-
Willis, B.C.1
Borok, Z.2
-
99
-
-
16844371760
-
A novel mechanism by which hepatocyte growth factor blocks tubular epithelial to mesenchymal transition
-
Yang J, Dai C, Liu Y. A novel mechanism by which hepatocyte growth factor blocks tubular epithelial to mesenchymal transition. J. Am. Soc. Nephrol. 16(1), 69-78 (2005).
-
(2005)
J. Am. Soc. Nephrol
, vol.16
, Issue.1
, pp. 69-78
-
-
Yang, J.1
Dai, C.2
Liu, Y.3
-
100
-
-
14844290237
-
Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney
-
Zeisberg M, Shah AA, Kalluri R. Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney. J. Biol. Chem. 280(9), 8094-8100 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, Issue.9
, pp. 8094-8100
-
-
Zeisberg, M.1
Shah, A.A.2
Kalluri, R.3
-
101
-
-
33745855458
-
Neutrophil elastase: Mediator of extracellular matrix destruction and accumulation
-
Chua F, Laurent GJ. Neutrophil elastase: mediator of extracellular matrix destruction and accumulation. Proc. Am. Thorac Soc. 3(5), 424-427 (2006).
-
(2006)
Proc. Am. Thorac Soc
, vol.3
, Issue.5
, pp. 424-427
-
-
Chua, F.1
Laurent, G.J.2
-
102
-
-
37549027570
-
Transforming growth factor-β activation in the lung: Focus on fibrosis and reactive oxygen species
-
Koli K, Myllarniemi M, Keski-Oja J, Kinnula VL. Transforming growth factor-β activation in the lung: focus on fibrosis and reactive oxygen species. Antioxid. Redox Signal. 10(2), 333-342 (2008).
-
(2008)
Antioxid. Redox Signal
, vol.10
, Issue.2
, pp. 333-342
-
-
Koli, K.1
Myllarniemi, M.2
Keski-Oja, J.3
Kinnula, V.L.4
-
103
-
-
28244500027
-
Antioxidant therapy for idiopathic pulmonary fibrosis
-
Hunninghake GW. Antioxidant therapy for idiopathic pulmonary fibrosis. N. Engl. J. Med. 353(21), 2285-2287 (2005).
-
(2005)
N. Engl. J. Med
, vol.353
, Issue.21
, pp. 2285-2287
-
-
Hunninghake, G.W.1
-
104
-
-
33747756116
-
Promising pharmacologic innovations in treating pulmonary fibrosis
-
Bhatr N, Baran CP, Allen J, Magro C, Marsh CB. Promising pharmacologic innovations in treating pulmonary fibrosis. Curr. Opin. Pharmacol. 6(3), 284-292 (2006).
-
(2006)
Curr. Opin. Pharmacol
, vol.6
, Issue.3
, pp. 284-292
-
-
Bhatr, N.1
Baran, C.P.2
Allen, J.3
Magro, C.4
Marsh, C.B.5
-
105
-
-
0142085920
-
Cytokine regulation of pulmonary fibrosis in scleroderma
-
Atamas SP, White B. Cytokine regulation of pulmonary fibrosis in scleroderma. Cytokine Growth Factor Rev. 14(6), 537-550 (2003).
-
(2003)
Cytokine Growth Factor Rev
, vol.14
, Issue.6
, pp. 537-550
-
-
Atamas, S.P.1
White, B.2
-
106
-
-
33744935771
-
Targeting genes for treatment in idiopathic pulmonary fibrosis: Challenges and opportunities, promises and pitfalls
-
Ask K, Martin GE, Kolb M, Gauldie J. Targeting genes for treatment in idiopathic pulmonary fibrosis: challenges and opportunities, promises and pitfalls. Proc. Am. Thorac Soc. 3(4), 389-393 (2006).
-
(2006)
Proc. Am. Thorac Soc
, vol.3
, Issue.4
, pp. 389-393
-
-
Ask, K.1
Martin, G.E.2
Kolb, M.3
Gauldie, J.4
-
107
-
-
33845358419
-
Prostaglandin E2 is a potent inhibitor of epithelial-to-mesenchymal transition: Interaction with hepatocyte growth factor
-
Zhang A, Wang MH, Dong Z, Yang T. Prostaglandin E2 is a potent inhibitor of epithelial-to-mesenchymal transition: interaction with hepatocyte growth factor. Am. J. Physiol. Renal Physiol. 291(6), F1323-F1331 (2006).
-
(2006)
Am. J. Physiol. Renal Physiol
, vol.291
, Issue.6
-
-
Zhang, A.1
Wang, M.H.2
Dong, Z.3
Yang, T.4
-
108
-
-
33846556197
-
Prostaglandin E2 inhibition of keloid fibroblast migration, contraction, and transforming growth factor (TGF)-β1-induced collagen synthesis
-
Sandulache VC, Parekh A, Li-Korotky H, Dohar JE, Hebda PA. Prostaglandin E2 inhibition of keloid fibroblast migration, contraction, and transforming growth factor (TGF)-β1-induced collagen synthesis. Wound Repair Regen. 15(1), 122-133 (2007).
-
(2007)
Wound Repair Regen
, vol.15
, Issue.1
, pp. 122-133
-
-
Sandulache, V.C.1
Parekh, A.2
Li-Korotky, H.3
Dohar, J.E.4
Hebda, P.A.5
-
109
-
-
34548498378
-
Inhibition of TGF-β induced lung fibroblast to myofibroblast conversion by phosphodiesterase inhibiting drugs and activators of soluble guanylyl cyclase
-
Dunkern TR, Feurstein D, Rossi GA. Sabatini F, Hatzelmann A. Inhibition of TGF-β induced lung fibroblast to myofibroblast conversion by phosphodiesterase inhibiting drugs and activators of soluble guanylyl cyclase. Eur. J. Pharmacol. 572(1), 12-22 (2007).
-
(2007)
Eur. J. Pharmacol
, vol.572
, Issue.1
, pp. 12-22
-
-
Dunkern, T.R.1
Feurstein, D.2
Rossi, G.A.3
Sabatini, F.4
Hatzelmann, A.5
-
110
-
-
33746215177
-
Role of 5-lipoxygenase in IL-13-induced pulmonary inflammation and remodeling
-
Shim YM, Zhu Z, Zheng T et al. Role of 5-lipoxygenase in IL-13-induced pulmonary inflammation and remodeling. J. Immunol. 177(3), 1918-1924 (2006).
-
(2006)
J. Immunol
, vol.177
, Issue.3
, pp. 1918-1924
-
-
Shim, Y.M.1
Zhu, Z.2
Zheng, T.3
-
111
-
-
0035083956
-
Transient transgene expression of decorin in the lung reduces the fibrotic response to bleomycin
-
Kolb M, Margetts PJ, Galt T et al. Transient transgene expression of decorin in the lung reduces the fibrotic response to bleomycin. Am. J. Respir. Crit. Care Med. 163(3 Pt 1), 770-777 (2001).
-
(2001)
Am. J. Respir. Crit. Care Med
, vol.163
, Issue.3 PART 1
, pp. 770-777
-
-
Kolb, M.1
Margetts, P.J.2
Galt, T.3
-
112
-
-
49049110677
-
Integrins and the activation of latent transforming growth factor β1 - an intimate relationship
-
Epub ahead of print
-
Wipff PJ, Hinz B. Integrins and the activation of latent transforming growth factor β1 - an intimate relationship. Eur. J. Cell Biol. (2008) (Epub ahead of print).
-
(2008)
Eur. J. Cell Biol
-
-
Wipff, P.J.1
Hinz, B.2
-
113
-
-
34247612439
-
New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis: A potential role for stem cells in the lung parenchyma and implications for therapy
-
Gharaee-Kermani M, Gyetko MR, Hu B, Phan SH. New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis: a potential role for stem cells in the lung parenchyma and implications for therapy. Pharm. Res. 24(5), 819-841 (2007).
-
(2007)
Pharm. Res
, vol.24
, Issue.5
, pp. 819-841
-
-
Gharaee-Kermani, M.1
Gyetko, M.R.2
Hu, B.3
Phan, S.H.4
-
114
-
-
0346094380
-
Bone marrow-derived cells contribute to lung regeneration after elastase-induced pulmonary emphysema
-
Ishizawa K, Kubo H, Yamada M et al. Bone marrow-derived cells contribute to lung regeneration after elastase-induced pulmonary emphysema. FEBS Lett. 556(1-3), 249-252 (2004).
-
(2004)
FEBS Lett
, vol.556
, Issue.1-3
, pp. 249-252
-
-
Ishizawa, K.1
Kubo, H.2
Yamada, M.3
-
115
-
-
0035805055
-
Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell
-
Krause DS, Theise ND, Collector MI et al. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 105 (3), 369-377 (2001).
-
(2001)
Cell
, vol.105
, Issue.3
, pp. 369-377
-
-
Krause, D.S.1
Theise, N.D.2
Collector, M.I.3
-
116
-
-
1642454668
-
Bone marrow-derived progenitor cells are important for lung repair after lipopolysaccharide-induced lung injury
-
Yamada M, Kubo H, Kobayashi S et al. Bone marrow-derived progenitor cells are important for lung repair after lipopolysaccharide-induced lung injury. J. Immunol. 172(2), 1266-1272 (2004).
-
(2004)
J. Immunol
, vol.172
, Issue.2
, pp. 1266-1272
-
-
Yamada, M.1
Kubo, H.2
Kobayashi, S.3
-
117
-
-
24344448730
-
Bone marrow-derived mesenchymal stem cells in repair of the injured lung
-
Rojas M, Xu J, Woods CR et al. Bone marrow-derived mesenchymal stem cells in repair of the injured lung. Am. J. Respir. Cell Mol. Biol. 33(2), 145-152 (2005).
-
(2005)
Am. J. Respir. Cell Mol. Biol
, vol.33
, Issue.2
, pp. 145-152
-
-
Rojas, M.1
Xu, J.2
Woods, C.R.3
-
118
-
-
0037478581
-
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects
-
Ortiz LA, Gambelli F, McBride C et al. Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects. Proc. Natl Acad. Sci. USA 100(14), 8407-8411 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, Issue.14
, pp. 8407-8411
-
-
Ortiz, L.A.1
Gambelli, F.2
McBride, C.3
|