Transforming growth factor-β1 genotype and susceptibility to chronic obstructive pulmonary disease

Thorax

Volumn 59, Issue 2, 2004, Pages 126-129

  Wu, L ^b   Chau, J ^b   Young, R P ^b   Pokorny, V ^b   Mills, G D ^c   Hopkins, R ^d   McLean, L ^e   Black, P N ^a,b  

^a AUCKLAND CITY HOSPITAL   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c WAIKATO HOSPITAL   (New Zealand)

^d GREEN LANE HOSPITAL   (New Zealand)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA1;

ADULT; ARTICLE; BLOOD DONOR; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SMOKING;

ADULT; AGED; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; REGRESSION ANALYSIS; SMOKING; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 1242329185     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thorax.2003.005769     Document Type: Article

References (25)

1. Fletcher C, Peto R. The natural history of chronic airflow obstruction. BMJ 1977;1:1645-8.
2. McCloskey SC, Patel BD, Hinchcliffe SJ, et al. Siblings of patients with severe obstructive pulmonary disease have a significant risk of airflow obstruction. Am J Respir Crit Care Med 2001;164:1419-24.
3. Hoidal JR. Genetics of COPD: present and future. Eur Respir J 2001;18:741-3.
4. Sporn MB, Roberts AB. Transforming growth factor-β multiple actions and potential clinical applications. JAMA 1989;262:938-41.
5. Letterio JJ, Roberts AB. Regulation of immune responses by TGF-β. Annu Rev Immunol 1998;16:137-61.
6. Eickelberg O, Kohler E, Reichenberger F, et al. Extracellular matrix deposition by primary human lung fibroblasts in response to TGF-beta1 and TGF-beta3. Am J Physiol 1999;276:L814-24.
7. Fang KC, Walters PJ, Steinhoff M, et al. Mast cell expression of gelatinases A and B is regulated by kit ligand and TGF-beta. J Immunol 1999;162:5528-35.
8. McGowan SE, Jackson SK, Olson PJ, et al. Exogenous and endogenous transforming growth factor-beta influence elastin gene expression in cultured lung fibroblasts. Am J Respir Cell Mol Biol 1997;17:25-35.
9. Kucich U, Rosenbloom JC, Abrams WR, et al. Transforming growth factor-beta stabilizes elastin mRNA by a pathway requiring active Smads, protein kinase C-delta and p38. Am J Respir Cell Mol Biol 2002;26:183-8.
10. Syrris P, Carter ND, Metcalfe JC, et al. Transforming growth factor-β1 gene polymorphisms and coronary artery disease. Clin Sci 1998;96:659-67.
11. Awad M, El-Gamel A, Hasleton P, et al. Genotypic variation in the transforming growth factor-β1 gene. Transplantation 1998;66:1014-20.
12. Lympany PA, Avila JJ, Mullighan C, et al. Rapid genotyping of transforming growth factor-β1 gene polymorphisms in a UK Caucasoid control population using the polymerase chain reaction and sequence-specific primers. Tissue Antigens 1998;52:573-8.
13. Cambien F, Ricard S, Troesch A, et al. Polymorphisms of the transforming growth factor-β1 gene in relation to myocardial infarction and blood pressure. The Etude Cas-Témoin de l'Infarctus du Myocarde (ECTIM) Study. Hypertension 1996;28:881-7.
14. 1 hyperexpression in African-American hypertensives: a novel mediator of hypertension and/or target organ damage. Proc Natl Acad Sci USA 2000;97:3479-84.
15. 1 gene with genetic susceptibility to osteoporosis in postmenopausal Japanese women. J Bone Miner Res 1998;13:1569-76.
16. 1 gene polymorphisms in patients with systemic sclerosis. Ann Rheum Dis 2002;61:678-81.
17. 1 gene-race interactions for resting and exercise blood pressure in the HERITAGE family study. J Appl Physiol 2001;91:1808-13.
18. American Thoracic Society. Standardization of spirometry, 1994 update: American Thoracic Society. Am J Respir Crit Care Med 1995;152:1107-36.
19. 1 genotype and accelerated decline in lung function of patients with cystic fibrosis. Thorax 2000;55:459-62.
20. Morris DG, Huang X, Kaminski N, et al. Loss of integrin αvβ6 mediated TGF-β activation causes MMP12-dependent emphysema. Nature 2003;422:169-73.
21. Cardon LR, Palmer LJ. Population stratification and spurious allelic association. Lancet 2003;361:598-604.
22. O'Brien C, Guest PJ, Hill SL, et al. Physiological and radiological characterization of patients diagnosed with chronic obstructive pulmonary disease in primary care. Thorax 2000;55:635-42.
23. Finlay GA, O'Donnell, O'Connor CM, et al. Elastin and collagen remodeling in emphysema. Am J Pathol 1996;149:1405-15.
24. Di Stefano A, Capelli A, Lusuardi M, et al. Severity of airflow limitation is associated with severity of airway inflammation in smokers. Am J Respir Crit Care Med 1996;153:530-4.
25. + T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998;157:822-6.