Inhibition of ICAM-1 gene expression, monocyte adhesion and cancer cell invasion by targetin IKK complex: Molecular and functional study of novel α-methylene-γ-butyrolactone derivatives

Carcinogenesis

Volumn 25, Issue 10, 2004, Pages 1925-1934

  Huang, Wei Chien ^a   Chan, Shu Ting ^a   Yang, Tzu Lin ^a   Tzeng, Cherng Chyi ^b   Chen, Ching Chow ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2; CYL 19S; CYL 26Z; GAMMA BUTYROLACTONE DERIVATIVE; GELATINASE B; I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOTRANSFERASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER INVASION; CELL ADHESION; CELL ASSAY; CELL LINE; CELL STRAIN U937; COMPLEX FORMATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVATION; ENZYME INHIBITION; EPITHELIUM CELL; GENE ACTIVITY; GENE EXPRESSION; GENE INDUCTION; GENE OVEREXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; IMMUNOREGULATION; LUNG ALVEOLUS EPITHELIUM; MOLECULAR BIOLOGY; MONOCYTE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WILD TYPE;

4-BUTYROLACTONE; ANTI-ULCER AGENTS; CELL ADHESION; CYCLOOXYGENASE 2; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B KINASE; INTERCELLULAR ADHESION MOLECULE-1; ISOENZYMES; LUCIFERASES; MATRIX METALLOPROTEINASE 9; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MONOCYTES; NEOPLASM INVASIVENESS; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS;

EID: 4944227529     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh211     Document Type: Article

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