Ergolide, sesquiterpene lactone from Inula britannica, inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-κB

British Journal of Pharmacology

Volumn 133, Issue 4, 2001, Pages 503-512

  Whan Han, Jeung ^a   Gon Lee, Byeong ^a   Kee Kim, Yong ^a   Woo Yoon, Jong ^a   Kyoung Jin, Hye ^a   Hong, Sungyoul ^a   Young Lee, Hoi ^b   Ro Lee, Kang ^a   Woo Lee, Hyang ^a  

^a Sungkyunkwan University   (South Korea)

^b Konyang University   (South Korea)

Author keywords

Cyclo oxygenase 2; Ergolide; Inducible nitric oxide synthase; I B; NF B

Indexed keywords

CYCLOOXYGENASE 2; CYSTEINE; ERGOLIDE; GAMMA INTERFERON; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INULA BRITANNICA EXTRACT; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE SYNTHASE; NITRITE; PLANT EXTRACT; PROSTAGLANDIN E2; PROTEIN SUBUNIT; SESQUITERPENE LACTONE; SYNAPTOTAGMIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DNA BINDING; ENZYME INHIBITION; IMMUNOBLOTTING; INULA BRITANNICA; MACROPHAGE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PLANT; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TRANSPORT;

INULA BRITANNICA;

EID: 0034955767     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704099     Document Type: Article

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