Conjugated polyhydroxybenzene derivatives block tumor necrosis factor-α-mediated nuclear factor-κB activation and cyclooxygenase-2 gene transcription by targeting IκB kinase activity

Molecular Pharmacology

Volumn 60, Issue 6, 2001, Pages 1439-1448

  Chen, C C ^a   Chiu, K T ^a   Chan, S T ^a   Chern, J W ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3',4' DIHYDROXYPHENYL) 5 HYDROXYBENZO[B]FURAN; 2,3 BIS(3',4' DIHYDROXYTRANSSTYRYL)PYRIDINE; CYCLOOXYGENASE 2; GF 105; GF 90; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN INDUCING KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN INDUCING KINASE BETA; IMMUNOGLOBULIN KAPPA CHAIN; MESSENGER RNA; PHENOL DERIVATIVE; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIUM CELL; GENE OVEREXPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS;

EID: 0035213899     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.60.6.1439     Document Type: Article

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