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Volumn 2, Issue 4, 2007, Pages 359-370

The glial response to CNS HIV infection includes p53 activation and increased expression of p53 target genes

Author keywords

Apoptosis; Astrocyte; Bax; HIV; Microglia; Neurodegeneration; Oligodendrocyte; p21(WAF1)

Indexed keywords

PROTEIN P53;

EID: 35648945862     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-007-9095-x     Document Type: Article
Times cited : (27)

References (77)
  • 5
    • 0032876814 scopus 로고    scopus 로고
    • The p53 pathway and apoptosis
    • 2
    • Burns TF, El-Deiry WS (1999) The p53 pathway and apoptosis. J Cell Physiol 181(2):231-239
    • (1999) J Cell Physiol , vol.181 , pp. 231-239
    • Burns, T.F.1    El-Deiry, W.S.2
  • 6
    • 0035961212 scopus 로고    scopus 로고
    • Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in the rat
    • 1
    • Casha S, Yu WR, Fehlings MG (2001) Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in the rat. Neuroscience 103(1):203-218
    • (2001) Neuroscience , vol.103 , pp. 203-218
    • Casha, S.1    Yu, W.R.2    Fehlings, M.G.3
  • 7
    • 33748432958 scopus 로고    scopus 로고
    • Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammation
    • 2
    • Cassiani-Ingoni R, Coksaygan T, Xue H, Reichert-Scrivner SA, Wiendl H, Rao MS, Magnus T (2006) Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammation. Exp Neurol 201(2):349-358
    • (2006) Exp Neurol , vol.201 , pp. 349-358
    • Cassiani-Ingoni, R.1    Coksaygan, T.2    Xue, H.3    Reichert-Scrivner, S.A.4    Wiendl, H.5    Rao, M.S.6    Magnus, T.7
  • 10
    • 0026607994 scopus 로고
    • P53 expression in brain after middle cerebral artery occlusion in the rat
    • 3
    • Chopp M, Li Y, Zhang ZG, Freytag SO (1992) p53 expression in brain after middle cerebral artery occlusion in the rat. Biochem Biophys Res Commun 182(3):1201-1207
    • (1992) Biochem Biophys Res Commun , vol.182 , pp. 1201-1207
    • Chopp, M.1    Li, Y.2    Zhang, Z.G.3    Freytag, S.O.4
  • 11
    • 0037418620 scopus 로고    scopus 로고
    • Neurobiological mediators of neuronal apoptosis in experimental neuroAIDS
    • 2-3
    • Corasaniti MT, Rotiroti D, Nappi G, Bagetta G (2003) Neurobiological mediators of neuronal apoptosis in experimental neuroAIDS. Toxicol Lett 139(2-3):199-206
    • (2003) Toxicol Lett , vol.139 , pp. 199-206
    • Corasaniti, M.T.1    Rotiroti, D.2    Nappi, G.3    Bagetta, G.4
  • 12
    • 0034622946 scopus 로고    scopus 로고
    • Evidence for independent development of resistance to HIV-1 reverse transcriptase inhibitors in the cerebrospinal fluid
    • 13
    • Cunningham PH, Smith DG, Satchell C, Cooper DA, Brew B (2000) Evidence for independent development of resistance to HIV-1 reverse transcriptase inhibitors in the cerebrospinal fluid. Aids 14(13):1949-1954
    • (2000) Aids , vol.14 , pp. 1949-1954
    • Cunningham, P.H.1    Smith, D.G.2    Satchell, C.3    Cooper, D.A.4    Brew, B.5
  • 13
    • 0031959496 scopus 로고    scopus 로고
    • P53- and CD95-associated apoptosis in neurodegenerative diseases
    • 4
    • de la Monte SM, Sohn YK, Ganju N, Wands JR (1998) P53- and CD95-associated apoptosis in neurodegenerative diseases. Lab Invest 78(4):401-411
    • (1998) Lab Invest , vol.78 , pp. 401-411
    • De La Monte, S.M.1    Sohn, Y.K.2    Ganju, N.3    Wands, J.R.4
  • 14
    • 0141758289 scopus 로고    scopus 로고
    • Enhanced oligodendrocyte survival after spinal cord injury in Bax-deficient mice and mice with delayed Wallerian degeneration
    • 25
    • Dong H, Fazzaro A, Xiang C, Korsmeyer SJ, Jacquin MF, McDonald JW (2003) Enhanced oligodendrocyte survival after spinal cord injury in Bax-deficient mice and mice with delayed Wallerian degeneration. J Neurosci 23(25):8682-8691
    • (2003) J Neurosci , vol.23 , pp. 8682-8691
    • Dong, H.1    Fazzaro, A.2    Xiang, C.3    Korsmeyer, S.J.4    Jacquin, M.F.5
  • 15
    • 0032895217 scopus 로고    scopus 로고
    • Cortical synaptic density is reduced in mild to moderate human immunodeficiency virus neurocognitive disorder. HNRC Group. HIV Neurobehavioral Research Center
    • 2
    • Everall IP, Heaton RK, Marcotte TD, Ellis RJ, McCutchan JA, Atkinson JH, Grant I, Mallory M, Masliah E (1999) Cortical synaptic density is reduced in mild to moderate human immunodeficiency virus neurocognitive disorder. HNRC Group. HIV Neurobehavioral Research Center. Brain Pathol 9(2):209-217
    • (1999) Brain Pathol , vol.9 , pp. 209-217
    • Everall, I.P.1    Heaton, R.K.2    Marcotte, T.D.3    Ellis, R.J.4    Atkinson, J.H.5    Grant, I.6    Mallory, M.7    Masliah, E.8
  • 16
    • 0036848969 scopus 로고    scopus 로고
    • Microglia in human immunodeficiency virus-associated neurodegeneration
    • 2
    • Garden GA (2002) Microglia in human immunodeficiency virus-associated neurodegeneration. Glia 40(2):240-251
    • (2002) Glia , vol.40 , pp. 240-251
    • Garden, G.A.1
  • 18
    • 0027155807 scopus 로고
    • Diffuse microgliosis associated with cerebral atrophy in the acquired immunodeficiency syndrome
    • 1
    • Gelman BB (1993) Diffuse microgliosis associated with cerebral atrophy in the acquired immunodeficiency syndrome. Ann Neurol 34(1):65-70
    • (1993) Ann Neurol , vol.34 , pp. 65-70
    • Gelman, B.B.1
  • 20
    • 0027343618 scopus 로고
    • Reactive glia as rivals in regulating neuronal survival
    • 1
    • Giulian D (1993) Reactive glia as rivals in regulating neuronal survival. Glia 7(1):102-110
    • (1993) Glia , vol.7 , pp. 102-110
    • Giulian, D.1
  • 21
    • 0025609978 scopus 로고
    • Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1
    • 4987
    • Giulian D, Vaca K, Noonan CA (1990) Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1. Science 250(4987):1593-1596
    • (1990) Science , vol.250 , pp. 1593-1596
    • Giulian, D.1    Vaca, K.2    Noonan, C.A.3
  • 22
    • 0027407936 scopus 로고
    • The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes
    • 7
    • Giulian D, Wendt E, Vaca K, Noonan CA (1993) The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes. Proc Natl Acad Sci USA 90(7):2769-2773
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 2769-2773
    • Giulian, D.1    Wendt, E.2    Vaca, K.3    Noonan, C.A.4
  • 23
    • 0028881820 scopus 로고
    • Cell surface morphology identifies microglia as a distinct class of mononuclear phagocyte
    • 11
    • Giulian D, Li J, Bartel S, Broker J, Li X, Kirkpatrick JB (1995) Cell surface morphology identifies microglia as a distinct class of mononuclear phagocyte. J Neurosci 15(11):7712-7726
    • (1995) J Neurosci , vol.15 , pp. 7712-7726
    • Giulian, D.1    Li, J.2    Bartel, S.3    Broker, J.4    Li, X.5    Kirkpatrick, J.B.6
  • 24
    • 0027436791 scopus 로고
    • Clinical-neuropathologic correlation in HIV-associated dementia
    • 11
    • Glass JD, Wesselingh SL, Selnes OA, McArthur JC (1993) Clinical-neuropathologic correlation in HIV-associated dementia. Neurology 43(11):2230-2237
    • (1993) Neurology , vol.43 , pp. 2230-2237
    • Glass, J.D.1    Wesselingh, S.L.2    Selnes, O.A.3
  • 25
    • 0028808135 scopus 로고
    • Immunocytochemical quantitation of human immunodeficiency virus in the brain: Correlations with dementia
    • 5
    • Glass JD, Fedor H, Wesselingh SL, McArthur JC (1995) Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia. Ann Neurol 38(5):755-762
    • (1995) Ann Neurol , vol.38 , pp. 755-762
    • Glass, J.D.1    Fedor, H.2    Wesselingh, S.L.3
  • 28
    • 2442494895 scopus 로고    scopus 로고
    • The common and distinct target genes of the p53 family transcription factors
    • 7-8
    • Harms K, Nozell S, Chen X (2004) The common and distinct target genes of the p53 family transcription factors. Cell Mol Life Sci 61(7-8):822-842
    • (2004) Cell Mol Life Sci , vol.61 , pp. 822-842
    • Harms, K.1    Nozell, S.2    Chen, X.3
  • 29
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • 6630
    • Haupt Y, Maya R, Kazaz A, Oren M (1997) Mdm2 promotes the rapid degradation of p53. Nature 387(6630):296-299
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 30
    • 0035826221 scopus 로고    scopus 로고
    • P53 protein accumulation in addition to the transactivation activity is required for p53-dependent cell cycle arrest after treatment of cells with camptothecin
    • 10
    • Jaks V, Joers A, Kristjuhan A, Maimets T (2001) p53 protein accumulation in addition to the transactivation activity is required for p53-dependent cell cycle arrest after treatment of cells with camptothecin. Oncogene 20(10):1212-1219
    • (2001) Oncogene , vol.20 , pp. 1212-1219
    • Jaks, V.1    Joers, A.2    Kristjuhan, A.3    Maimets, T.4
  • 31
    • 0026767492 scopus 로고
    • Epidemiology of human immunodeficiency virus encephalopathy in the United States
    • 8
    • Janssen RS, Nwanyanwu OC, Selik RM, Stehr-Green JK (1992) Epidemiology of human immunodeficiency virus encephalopathy in the United States. Neurology 42(8):1472-1476
    • (1992) Neurology , vol.42 , pp. 1472-1476
    • Janssen, R.S.1    Nwanyanwu, O.C.2    Selik, R.M.3    Stehr-Green, J.K.4
  • 32
    • 0035077448 scopus 로고    scopus 로고
    • Problems of cell death in neurodegeneration and Alzheimer's Disease
    • 1
    • Jellinger KA, Stadelmann C (2001) Problems of cell death in neurodegeneration and Alzheimer's Disease. J Alzheimers Dis 3(1):31-40
    • (2001) J Alzheimers Dis , vol.3 , pp. 31-40
    • Jellinger, K.A.1    Stadelmann, C.2
  • 33
    • 0033529303 scopus 로고    scopus 로고
    • Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis
    • 14
    • Kaul M, Lipton SA (1999) Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis. Proc Natl Acad Sci USA 96(14):8212-8216
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 8212-8216
    • Kaul, M.1    Lipton, S.A.2
  • 34
    • 1542726344 scopus 로고    scopus 로고
    • Signaling pathways to neuronal damage and apoptosis in human immunodeficiency virus type 1-associated dementia: Chemokine receptors, excitotoxicity, and beyond
    • Suppl 1
    • Kaul M, Lipton SA (2004) Signaling pathways to neuronal damage and apoptosis in human immunodeficiency virus type 1-associated dementia: chemokine receptors, excitotoxicity, and beyond. J Neurovirol 10(Suppl 1):97-101
    • (2004) J Neurovirol , vol.10 , pp. 97-101
    • Kaul, M.1    Lipton, S.A.2
  • 35
    • 0035912198 scopus 로고    scopus 로고
    • Pathways to neuronal injury and apoptosis in HIV-associated dementia
    • 6831
    • Kaul M, Garden GA, Lipton SA (2001) Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 410(6831):988-994
    • (2001) Nature , vol.410 , pp. 988-994
    • Kaul, M.1    Garden, G.A.2    Lipton, S.A.3
  • 36
    • 0034788643 scopus 로고    scopus 로고
    • Pathways of neuron-astrocyte interactions and their possible role in neuroprotection
    • 4
    • Kirchhoff F, Dringen R, Giaume C (2001) Pathways of neuron-astrocyte interactions and their possible role in neuroprotection. Eur Arch Psychiatry Clin Neurosci 251(4):159-169
    • (2001) Eur Arch Psychiatry Clin Neurosci , vol.251 , pp. 159-169
    • Kirchhoff, F.1    Dringen, R.2    Giaume, C.3
  • 38
    • 0030965946 scopus 로고    scopus 로고
    • Regulation of p53 stability by Mdm2
    • 6630
    • Kubbutat MH, Jones SN, Vousden KH (1997) Regulation of p53 stability by Mdm2. Nature 387(6630):299-303
    • (1997) Nature , vol.387 , pp. 299-303
    • Kubbutat, M.H.1    Jones, S.N.2    Vousden, K.H.3
  • 39
    • 0344406085 scopus 로고    scopus 로고
    • Changing patterns in the neuropathogenesis of HIV during the HAART era
    • 2
    • Langford TD, Letendre SL, Larrea GJ, Masliah E (2003) Changing patterns in the neuropathogenesis of HIV during the HAART era. Brain Pathol 13(2):195-210
    • (2003) Brain Pathol , vol.13 , pp. 195-210
    • Langford, T.D.1    Letendre, S.L.2    Larrea, G.J.3    Masliah, E.4
  • 40
    • 0028909868 scopus 로고
    • Seminars in medicine of the Beth Israel Hospital, Boston. Dementia associated with the acquired immunodeficiency syndrome
    • 14
    • Lipton SA, Gendelman HE (1995) Seminars in medicine of the Beth Israel Hospital, Boston. Dementia associated with the acquired immunodeficiency syndrome. N Engl J Med 332(14):934-940
    • (1995) N Engl J Med , vol.332 , pp. 934-940
    • Lipton, S.A.1    Gendelman, H.E.2
  • 42
    • 0034717014 scopus 로고    scopus 로고
    • Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling
    • 21
    • Marchenko ND, Zaika A, Moll UM (2000) Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J Biol Chem 275(21):16202-16212
    • (2000) J Biol Chem , vol.275 , pp. 16202-16212
    • Marchenko, N.D.1    Zaika, A.2    Moll, U.M.3
  • 43
    • 0034517935 scopus 로고    scopus 로고
    • P53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis
    • 6 Pt B
    • Martin LJ (2000) p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis. Neurobiol Dis 7(6 Pt B):613-622
    • (2000) Neurobiol Dis , vol.7 , pp. 613-622
    • Martin, L.J.1
  • 44
    • 0036260697 scopus 로고    scopus 로고
    • Cellular response to oxidative stress: Signaling for suicide and survival
    • 1
    • Martindale JL, Holbrook NJ (2002) Cellular response to oxidative stress: signaling for suicide and survival. J Cell Physiol 192(1):1-15
    • (2002) J Cell Physiol , vol.192 , pp. 1-15
    • Martindale, J.L.1    Holbrook, N.J.2
  • 45
    • 33646198141 scopus 로고    scopus 로고
    • Olig2-positive progenitors in the embryonic spinal cord give rise not only to motoneurons and oligodendrocytes, but also to a subset of astrocytes and ependymal cells
    • 2
    • Masahira N, Takebayashi H, Ono K, Watanabe K, Ding L, Furusho M, Ogawa Y, Nabeshima Y, Alvarez-Buylla A, Shimizu K, Ikenaka K (2006) Olig2-positive progenitors in the embryonic spinal cord give rise not only to motoneurons and oligodendrocytes, but also to a subset of astrocytes and ependymal cells. Dev Biol 293(2):358-369
    • (2006) Dev Biol , vol.293 , pp. 358-369
    • Masahira, N.1    Takebayashi, H.2    Ono, K.3    Watanabe, K.4    Ding, L.5    Furusho, M.6    Ogawa, Y.7    Nabeshima, Y.8    Alvarez-Buylla, A.9    Shimizu, K.10    Ikenaka, K.11
  • 47
    • 0031470192 scopus 로고    scopus 로고
    • Dendritic injury is a pathological substrate for human immunodeficiency virus-related cognitive disorders. HNRC Group. the HIV Neurobehavioral Research Center
    • 6
    • Masliah E, Heaton RK, Marcotte TD, Ellis RJ, Wiley CA, Mallory M, Achim CL, McCutchan JA, Nelson JA, Atkinson JH, Grant I (1997) Dendritic injury is a pathological substrate for human immunodeficiency virus-related cognitive disorders. HNRC Group. The HIV Neurobehavioral Research Center. Ann Neurol 42(6):963-972
    • (1997) Ann Neurol , vol.42 , pp. 963-972
    • Masliah, E.1    Heaton, R.K.2    Marcotte, T.D.3    Ellis, R.J.4    Wiley, C.A.5    Mallory, M.6    Achim, C.L.7    Nelson, J.A.8    Atkinson, J.H.9    Grant, I.10
  • 51
    • 11444256801 scopus 로고    scopus 로고
    • Glia and their cytokines in progression of neurodegeneration
    • 3
    • Mrak RE, Griffin WS (2005) Glia and their cytokines in progression of neurodegeneration. Neurobiol Aging 26(3):349-354
    • (2005) Neurobiol Aging , vol.26 , pp. 349-354
    • Mrak, R.E.1    Griffin, W.S.2
  • 52
    • 0033059025 scopus 로고    scopus 로고
    • The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury
    • 1
    • Napieralski JA, Raghupathi R, McIntosh TK (1999) The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury. Brain Res Mol Brain Res 71(1):78-86
    • (1999) Brain Res Mol Brain Res , vol.71 , pp. 78-86
    • Napieralski, J.A.1    Raghupathi, R.2
  • 53
    • 22744434226 scopus 로고    scopus 로고
    • Cell death mechanisms in HIV-associated dementia: The involvement of syncytia
    • Suppl 1
    • Nardacci R, Antinori A, Kroemer G, Piacentini M (2005a) Cell death mechanisms in HIV-associated dementia: the involvement of syncytia. Cell Death Differ 12(Suppl 1):855-858
    • (2005) Cell Death Differ , vol.12 , pp. 855-858
    • Nardacci, R.1    Antinori, A.2    Kroemer, G.3    Piacentini, M.4
  • 55
    • 0032880444 scopus 로고    scopus 로고
    • Pathobiology of human immunodeficiency virus dementia
    • 2
    • Nath A (1999) Pathobiology of human immunodeficiency virus dementia. Semin Neurol 19(2):113-127
    • (1999) Semin Neurol , vol.19 , pp. 113-127
    • Nath, A.1
  • 56
    • 3042816808 scopus 로고    scopus 로고
    • The role of excitotoxicity in secondary mechanisms of spinal cord injury: A review with an emphasis on the implications for white matter degeneration
    • 6
    • Park E, Velumian AA, Fehlings MG (2004) The role of excitotoxicity in secondary mechanisms of spinal cord injury: a review with an emphasis on the implications for white matter degeneration. J Neurotrauma 21(6):754-774
    • (2004) J Neurotrauma , vol.21 , pp. 754-774
    • Park, E.1    Velumian, A.A.2    Fehlings, M.G.3
  • 58
    • 0029065185 scopus 로고
    • Evidence of apoptotic cell death in HIV encephalitis
    • 5
    • Petito CK, Roberts B (1995) Evidence of apoptotic cell death in HIV encephalitis. Am J Pathol 146(5):1121-1130
    • (1995) Am J Pathol , vol.146 , pp. 1121-1130
    • Petito, C.K.1    Roberts, B.2
  • 59
    • 0036895062 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy and apoptosis of infected oligodendrocytes in the central nervous system of patients with and without AIDS
    • 12
    • Richardson-Burns SM, Kleinschmidt-DeMasters BK, DeBiasi RL, Tyler KL (2002) Progressive multifocal leukoencephalopathy and apoptosis of infected oligodendrocytes in the central nervous system of patients with and without AIDS. Arch Neurol 59(12):1930-1936
    • (2002) Arch Neurol , vol.59 , pp. 1930-1936
    • Richardson-Burns, S.M.1    Kleinschmidt-Demasters, B.K.2    Debiasi, R.L.3    Tyler, K.L.4
  • 61
    • 0032585811 scopus 로고    scopus 로고
    • Neuronal cell death in down's syndrome
    • Sawa A (1999) Neuronal cell death in down's syndrome. J Neural Transm Suppl 57:87-97
    • (1999) J Neural Transm Suppl , vol.57 , pp. 87-97
    • Sawa, A.1
  • 63
    • 0030695396 scopus 로고    scopus 로고
    • Apoptosis of microglia and oligodendrocytes after spinal cord contusion in rats
    • 5
    • Shuman SL, Bresnahan JC, Beattie MS (1997) Apoptosis of microglia and oligodendrocytes after spinal cord contusion in rats. J Neurosci Res 50(5):798-808
    • (1997) J Neurosci Res , vol.50 , pp. 798-808
    • Shuman, S.L.1    Bresnahan, J.C.2    Beattie, M.S.3
  • 64
    • 0242321735 scopus 로고    scopus 로고
    • Growth hormone prevents human immunodeficiency virus-induced neuronal p53 expression
    • 5
    • Silva C, Zhang K, Tsutsui S, Holden JK, Gill MJ, Power C (2003) Growth hormone prevents human immunodeficiency virus-induced neuronal p53 expression. Ann Neurol 54(5):605-614
    • (2003) Ann Neurol , vol.54 , pp. 605-614
    • Silva, C.1    Zhang, K.2    Tsutsui, S.3    Holden, J.K.4    Gill, M.J.5    Power, C.6
  • 65
    • 0033230581 scopus 로고    scopus 로고
    • The cellular response to p53: The decision between life and death
    • 45
    • Sionov RV, Haupt Y (1999) The cellular response to p53: the decision between life and death. Oncogene 18(45):6145-6157
    • (1999) Oncogene , vol.18 , pp. 6145-6157
    • Sionov, R.V.1    Haupt, Y.2
  • 66
    • 0030038103 scopus 로고    scopus 로고
    • Oxidative stress, caloric restriction, and aging
    • 5271
    • Sohal RS, Weindruch R (1996) Oxidative stress, caloric restriction, and aging. Science 273(5271):59-63
    • (1996) Science , vol.273 , pp. 59-63
    • Sohal, R.S.1    Weindruch, R.2
  • 68
    • 1942520401 scopus 로고    scopus 로고
    • Astrocyte apoptosis: Implications for neuroprotection
    • 2
    • Takuma K, Baba A, Matsuda T (2004) Astrocyte apoptosis: implications for neuroprotection. Prog Neurobiol 72(2):111-127
    • (2004) Prog Neurobiol , vol.72 , pp. 111-127
    • Takuma, K.1    Baba, A.2    Matsuda, T.3
  • 69
    • 0034991252 scopus 로고    scopus 로고
    • Correlation between neurological progression and astrocyte apoptosis in HIV-associated dementia
    • 6
    • Thompson KA, McArthur JC, Wesselingh SL (2001) Correlation between neurological progression and astrocyte apoptosis in HIV-associated dementia. Ann Neurol 49(6):745-752
    • (2001) Ann Neurol , vol.49 , pp. 745-752
    • Thompson, K.A.1    Wesselingh, S.L.2
  • 71
  • 72
    • 0034991754 scopus 로고    scopus 로고
    • Immunopathogenesis of HIV-associated dementia
    • 3
    • Wesselingh SL, Thompson KA (2001) Immunopathogenesis of HIV-associated dementia. Curr Opin Neurol 14(3):375-379
    • (2001) Curr Opin Neurol , vol.14 , pp. 375-379
    • Wesselingh, S.L.1    Thompson, K.A.2
  • 74
    • 0033784427 scopus 로고    scopus 로고
    • Expression of Bax, Bcl-2, and P53 in progressive multifocal leukoencephalopathy
    • 10
    • Yang B, Prayson RA (2000) Expression of Bax, Bcl-2, and P53 in progressive multifocal leukoencephalopathy. Mod Pathol 13(10):1115-1120
    • (2000) Mod Pathol , vol.13 , pp. 1115-1120
    • Yang, B.1    Prayson, R.A.2
  • 77
    • 18144416611 scopus 로고    scopus 로고
    • The transcriptional targets of p53 in apoptosis control
    • 3
    • Yu J, Zhang L (2005) The transcriptional targets of p53 in apoptosis control. Biochem Biophys Res Commun 331(3):851-858
    • (2005) Biochem Biophys Res Commun , vol.331 , pp. 851-858
    • Yu, J.1    Zhang, L.2


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