Posttranslational control of the Neurospora circadian clock

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 72, Issue , 2007, Pages 185-191

  Cha, J ^a   Huang, G ^a   Guo, J ^a   Liu, Y ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FRQ PROTEIN, NEUROSPORA CRASSA; FUNGAL PROTEIN; COP9 SIGNALOSOME; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CLOCK; TRANSCRIPTION FACTOR FRQ; TRANSCRIPTION FACTOR WC 1; TRANSCRIPTION FACTOR WC 2; UNCLASSIFIED DRUG;

BIOLOGICAL MODEL; CIRCADIAN RHYTHM; FEEDBACK SYSTEM; GENETICS; METABOLISM; NEUROSPORA; PHYSIOLOGY; PROTEIN PROCESSING; REVIEW; TRANSACTIVATION; DROSOPHILA; EUKARYOTE; FUNGAL STRAIN; MOLECULAR EVOLUTION; NEGATIVE FEEDBACK; NONHUMAN; OPEN READING FRAME; OSCILLATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REPRESSOR GENE;

CIRCADIAN RHYTHM; FEEDBACK, BIOCHEMICAL; FUNGAL PROTEINS; MODELS, BIOLOGICAL; NEUROSPORA; PROTEIN PROCESSING, POST-TRANSLATIONAL; TRANS-ACTIVATION (GENETICS);

EID: 48249105819     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.2007.72.010     Document Type: Conference Paper

References (70)

1. Aronson B.D., Johnson K.A., Loros J.J., and Dunlap J.C. 1994. Negative feedback defining a circadian clock: Autoregulation of the clock gene frequency. Science 263: 1578.
2. Ballario P., Vittorioso P., Magrelli A., Talora C., Cabibbo A., and Macino G. 1996. White collar-1, a central regulator of blue light responses in Neurospora, is a zinc finger protein. EMBO J. 15: 1650.
3. Busino L., Bassermann F., Maiolica A., Lee C., Nolan P.M., Godinho S.I., Draetta G.F., and Pagano M. 2007. SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins. Science 316: 900.
4. Cheng P., Yang Y., and Liu Y. 2001a. Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock. Proc. Natl. Acad. Sci. 98: 7408.
5. Cheng P., Yang Y., Gardner K.H., and Liu Y. 2002. PAS domain-mediated WC-1/WC-2 interaction is essential for maintaining the steady-state level of WC-1 and the function of both proteins in circadian clock and light responses of Neurospora. Mol. Cell. Biol. 22: 517.
6. Cheng P., Yang Y., Heintzen C., and Liu Y. 2001b. Coiled-coil domain-mediated FRQ-FRQ interaction is essential for its circadian clock function in Neurospora. EMBO J. 20: 101.
7. Cheng P., He Q., He Q., Wang L., and Liu Y. 2005. Regulation of the Neurospora circadian clock by an RNA helicase. Genes Dev. 19: 234.
8. Cheng P., He Q., Yang Y., Wang L., and Liu Y. 2003a. Functional conservation of light, oxygen, or voltage domains in light sensing. Proc. Natl. Acad. Sci. 100: 5938.
9. Cheng P., Yang Y., Wang L., He Q. and Liu Y. 2003b. WHITE COLLAR-1, a multifunctional Neurospora protein involved in the circadian feedback loops, light sensing, and transcription repression of wc-2. J. Biol. Chem. 278: 3801.
10. Collett M.A., Garceau N., Dunlap J.C., and Loros J.J. 2002. Light and clock expression of the Neurospora clock gene frequency is differentially driven by but dependent on WHITE COLLAR-2. Genetics 160: 149.
11. Crosthwaite S.K., Dunlap J.C., and Loros J.J. 1997. Neurospora wc-1 and wc-2: Transcription, photoresponses, and the origins of circadian rhythmicity. Science 276: 763.
12. Crosthwaite S.K., Loros J.J., and Dunlap J.C. 1995. Light-induced resetting of a circadian clock is mediated by a rapid increase in frequency transcript. Cell 81: 1003.
13. de la Cruz J., Kressler D., Tollervey D., and Linder P. 1998. Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3′ end formation of 5.8S rRNA in Saccharomyces cerevisiae. EMBO J. 17: 1128.
14. Diernfellner A.C., Schafmeier T., Merrow M.W., and Brunner M. 2005. Molecular mechanism of temperature sensing by the circadian clock of Neurospora crassa. Genes Dev. 19: 1968.
15. Dunlap J.C. 1999. Molecular bases for circadian clocks. Cell 96: 271.
16. Dunlap J.C. and Loros J.J. 2004. The Neurospora circadian system. J. Biol. Rhythms 19: 414.
17. Eide E.J., Woolf M.F., Kang H., Woolf P., Hurst W., Camacho F., Vielhaber E.L., Giovanni A., and Virshup D.M. 2005. Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation. Mol. Cell. Biol. 25: 2795.
18. Froehlich A.C., Loros J.J. and Dunlap J.C. 2003. Rhythmic binding of a WHITE COLLAR-containing complex to the frequency promoter is inhibited by FREQUENCY. Proc. Natl. Acad. Sci. 100: 5914.
19. Froehlich A.C., Liu Y., Loros J.J., and Dunlap J.C. 2002. White Collar-1, a circadian blue light photoreceptor, binding to the frequency promoter. Science 297: 815.
20. Gallego M. and Virshup D.M. 2007. Post-translational modifications regulate the ticking of the circadian clock. Nat. Rev. Mol. Cell Biol. 8: 139.
21. Garceau N.Y., Liu Y., Loros J.J., and Dunlap J.C. 1997. Alternative initiation of translation and time-specific phosphorylation yield multiple forms of the essential clock protein FREQUENCY. Cell 89: 469.
22. Glossop N.R., Lyons L.C., and Hardin P.E. 1999. Interlocked feedback loops within the Drosophila circadian oscillator. Science 286: 766.
23. Godinho S.I., Maywood E.S., Shaw L., Tucci V., Barnard A.R., Busino L., Pagano M., Kendall R., Quwailid M.M., Romero M.R., O'Neill J., Chesham J.E., Brooker D., Lalanne Z., Hastings M.H., and Nolan P.M. 2007. The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period. Science 316: 897.
24. Gorl M., Merrow M., Huttner B., Johnson J., Roenneberg T., and Brunner M. 2001. A PEST-like element in FREQUENCY determines the length of the circadian period in Neurospora crassa. EMBO J. 20: 7074.
25. Grima B., Lamouroux A., Chelot E., Papin C., Limbourg-Bouchon B., and Rouyer F. 2002. The F-box protein slimb controls the levels of clock proteins period and timeless. Nature 420: 178.
26. He Q. and Liu Y. 2005. Molecular mechanism of light responses in Neurospora: From light-induced transcription to photoadaptation. Genes Dev. 19: 2888.
27. He Q., Cheng P., He Q., and Liu Y. 2005a. The COP9 signalosome regulates the Neurospora circadian clock by controlling the stability of the SCFFWD-1 complex. Genes Dev. 19: 1518.
28. He Q., Cha J., He Q., Lee H.C., Yang Y., and Liu Y. 2006. CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loop. Genes Dev. 20: 2552.
29. He Q., Cheng P., Yang Y., He Q., Yu H., and Liu Y. 2003. FWD1-mediated degradation of FREQUENCY in Neurospora establishes a conserved mechanism for circadian clock regulation. EMBO J. 22: 4421.
30. He Q., Cheng P., Yang Y., Wang L., Gardner K.H., and Liu Y. 2002. White collar-1, a DNA binding transcription factor and a light sensor. Science 297: 8403.
31. He Q., Shu H., Cheng P., Chen S., Wang L., and Liu Y. 2005b. Light-independent phosphorylation of WHITE COLLAR-1 regulates its function in the Neurospora circadian negative feedback loop. J. Biol. Chem. 280: 17526.
32. Heintzen C. and Liu Y. 2007. The Neurospora crassa circadian clock. Adv. Genet. 58: 25.
33. Hilleren P.J. and Parker R. 2003. Cytoplasmic degradation of splice-defective pre-mRNAs and intermediates. Mol. Cell 12: 1453.
34. Huang G., Wang L., and Liu Y. 2006. Molecular mechanism of suppression of circadian rhythms by a critical stimulus. EMBO J. 25: 5349.
35. Kim E.Y. and Edery I. 2006. Balance between DBT/CKIepsilon kinase and protein phosphatase activities regulate phosphorylation and stability of Drosophila CLOCK protein. Proc. Natl. Acad. Sci. 103: 6178.
36. Kim E.Y., Ko H.W., Yu W., Hardin P.E., and Edery I. 2007. A DOUBLETIME kinase binding domain on the Drosophila PERIOD protein is essential for its hyperphosphorylation, transcriptional repression, and circadian clock function. Mol. Cell. Biol. 27: 5014.
37. Kloss B., Price J.L., Saez L., Blau J., Rothenfluh A., Wesley C.S., and Young M.W. 1998. The Drosophila clock gene double-time encodes a protein closely related to human casein kinase Iepsilon. Cell 94: 97.
38. Ko H.W., Jiang J., and Edery I. 2002. Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime. Nature 420: 673.
39. Koh K., Zheng X., and Sehgal A. 2006. JETLAG resets the Drosophila circadian clock by promoting light-induced degradation of TIMELESS. Science 312: 1809.
40. Lee C., Weaver D.R., and Reppert S.M. 2004. Direct association between mouse PERIOD and CKIepsilon is critical for a functioning circadian clock. Mol. Cell. Biol. 24: 584.
41. Lee C., Etchegaray J.P., Cagampang F.R., Loudon A.S., and Reppert S.M. 2001. Posttranslational mechanisms regulate the mammalian circadian clock. Cell 107: 855.
42. Lee K., Loros J.J., and Dunlap J.C. 2000. Interconnected feedback loops in the Neurospora circadian system. Science 289: 107.
43. Linden H. and Macino G. 1997. White collar 2, a partner in bluelight signal transduction, controlling expression of light-regulated genes in Neurospora crassa. EMBO J. 16: 98.
44. Liu Y. 2003. Molecular mechanisms of entrainment in the Neurospora circadian clock. J. Biol. Rhythms 18: 195.
45. -. 2005. Analysis of posttranslational regulations in the Neurospora circadian clock. Methods Enzymol. 393: 379.
46. Liu Y. and Bell-Pedersen D. 2006. Circadian rhythms in Neurospora crassa and other filamentous fungi. Eukaryot. Cell 5: 1184.
47. Liu Y., Loros J., and Dunlap J.C. 2000. Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock. Proc. Natl. Acad. Sci. 97: 234.
48. Liu Y., Merrow M., Loros J.J., and Dunlap J.C. 1998. How temperature changes reset a circadian oscillator. Science 281: 825.
49. Luo C., Loros J.J., and Dunlap J.C. 1998. Nuclear localization is required for function of the essential clock protein FRQ. EMBO J. 17: 1228.
50. Merrow M.W., Garceau N.Y., and Dunlap J.C. 1997. Dissection of a circadian oscillation into discrete domains. Proc. Natl. Acad. Sci. 94: 3877.
51. Merrow M., Franchi L., Dragovic Z., Gorl M., Johnson J., Brunner M., Macino G., and Roenneberg T. 2001. Circadian regulation of the light input pathway in Neurospora crassa. EMBO J. 20: 307.
52. Mitchell P. and Tollervey D. 2000. Musing on the structural organization of the exosome complex. Nat. Struct. Biol. 7: 843.
53. Nakajima M., Imai K., Ito H., Nishiwaki T., Murayama Y., Iwasaki H., Oyama T., and Kondo T. 2005. Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro. Science 308: 414.
54. Nawathean P. and Rosbash M. 2004. The doubletime and CKII kinases collaborate to potentiate Drosophila PER transcriptional repressor activity. Mol. Cell 13: 213.
55. Sathyanarayanan S., Zheng X., Xiao R., and Sehgal A. 2004. Posttranslational regulation of Drosophila PERIOD protein by protein phosphatase 2A. Cell 116: 603.
56. Schafmeier T., Kaldi K., Diernfellner A., Mohr C., and Brunner M. 2006. Phosphorylation-dependent maturation of Neurospora circadian clock protein from a nuclear repressor toward a cytoplasmic activator. Genes Dev. 20: 297.
57. Schafmeier T., Haase A., Kaldi K., Scholz J., Fuchs M., and Brunner M. 2005. Transcriptional feedback of Neurospora circadian clock gene by phosphorylation-dependent inactivation of its transcription factor. Cell 122: 235.
58. Schwerdtfeger C. and Linden H. 2000. Localization and light-dependent phosphorylation of white collar 1 and 2, the two central components of blue light signaling in Neurospora crassa. Eur. J. Biochem. 267: 414.
59. Shearman L.P., Sriram S., Weaver D.R., Maywood E.S., Chaves I., Zheng B., Kume K., Lee C.C., van der Horst G.T., Hastings M.H., and Reppert S.M. 2000. Interacting molecular loops in the mammalian circadian clock. Science 288: 1013.
60. Siepka S.M., Yoo S.H., Park J., Song W., Kumar V., Hu Y., Lee C., and Takahashi J.S. 2007. Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression. Cell 129: 1011.
61. Sugano S., Andronis C., Green R.M., Wang Z.Y., and Tobin E.M. 1998. Protein kinase CK2 interacts with and phosphorylates the Arabidopsis circadian clock-associated 1 protein. Proc. Natl. Acad. Sci. 95: 11020.
62. Talora C., Franchi L., Linden H., Ballario P., and Macino G. 1999. Role of a white collar-1-white collar-2 complex in bluelight signal transduction. EMBO J. 18: 4961.
63. Toh K.L., Jones C.R., He Y., Eide E.J., Hinz W.A., Virshup D.M., Ptacek L.J. and Fu Y.H. 2001. An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science 291: 1040.
64. Xu Y., Padiath Q.S., Shapiro R.E., Jones C.R., Wu S.C., Saigoh N., Saigoh K., Ptacek L.J., and Fu Y.H. 2005. Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome. Nature 434: 640.
65. Yang Y., Cheng P., and Liu Y. 2002. Regulation of the Neurospora circadian clock by casein kinase II. Genes Dev. 16: 994.
66. Yang Y., Cheng P., Zhi G., and Liu Y. 2001. Identification of a calcium/calmodulin-dependent protein kinase that phosphorylates the Neurospora circadian clock protein FREQUENCY. J. Biol. Chem. 276: 41064.
67. Yang Y., Cheng P., He Q., Wang L., and Liu Y. 2003. Phosphorylation of FREQUENCY protein by casein kinase II is necessary for the function of the Neurospora circadian clock. Mol. Cell. Biol. 23: 6221.
68. Yang Y., He Q., Cheng P., Wrage P., Yarden O., and Liu Y. 2004. Distinct roles for PP1 and PP2A in the Neurospora circadian clock. Genes Dev. 18: 255.
69. Young M.W. and Kay S.A. 2001. Time zones: A comparative genetics of circadian clocks. Nat. Rev. Genet. 2: 702.
70. Yu W., Zheng H., Houl J.H., Dauwalder B., and Hardin P.E. 2006. PER-dependent rhythms in CLK phosphorylation and E-box binding regulate circadian transcription. Genes Dev. 20: 723.