The Neurospora crassa Circadian Clock

Advances in Genetics

Volumn 58, Issue , 2007, Pages 25-66

  Heintzen, Christian ^a   Liu, Yi ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; FRQ PROTEIN, NEUROSPORA CRASSA; FUNGAL PROTEIN; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE; TRANSCRIPTION FACTOR; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; WC 1 PROTEIN, NEUROSPORA CRASSA; WC-1 PROTEIN, NEUROSPORA CRASSA; WHITE COLLAR 2 PROTEIN, NEUROSPORA;

ANIMAL; BIOLOGICAL MODEL; BIOLOGICAL RHYTHM; CIRCADIAN RHYTHM; FEEDBACK SYSTEM; GENETIC TRANSCRIPTION; GENETICS; LIGHT; METABOLISM; MOLECULAR EVOLUTION; NEUROSPORA CRASSA; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; REVIEW; TEMPERATURE; TIME;

ANIMALS; BIOLOGICAL CLOCKS; CIRCADIAN RHYTHM; DNA-BINDING PROTEINS; EVOLUTION, MOLECULAR; FEEDBACK; FUNGAL PROTEINS; LIGHT; MODELS, BIOLOGICAL; NEUROSPORA CRASSA; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; SKP CULLIN F-BOX PROTEIN LIGASES; TEMPERATURE; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 34247161251     PISSN: 00652660     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-2660(06)58002-2     Document Type: Review

References (149)

1. Akten B., Jauch E., Genova G.K., Kim E.Y., Edery I., Raabe T., and Jackson F.R. A role for CK2 in the Drosophila circadian oscillator. Nat. Neurosci. 6 (2003) 251-257
2. Allmang C., Kufel J., Chanfreau G., Mitchell P., Petfalski E., and Tollervey D. Functions of the exosome in rRNA, snoRNA and snRNA synthesis. EMBO J. 18 (1999) 5399-5410
3. Aronson B.D., Johnson K.A., Loros J.J., and Dunlap J.C. Negative feedback defining a circadian clock: Autoregulation in the clock gene frequency. Science 263 (1994) 1578-1584
4. Aronson B.D., Johnson K.A., and Dunlap J.C. The circadian clock locus frequency: A single ORF defines period length and temperature compensation. Proc. Natl. Acad. Sci. USA 91 (1994) 7683-7687
5. Ashmore L.J., and Sehgal A. A fly's eye view of circadian entrainment. J. Biol. Rhythms 18 (2003) 206-216
6. Ballario P., Vittorioso P., Magrelli A., Talora C., Cabibbo A., and Macino G. White collar-1, a central regulator of blue-light responses in Neurospora crassa, is a zinc-finger protein. EMBO J. 15 (1996) 1650-1657
7. Ballario P., Talora C., Galli D., Linden H., and Macino G. Roles in dimerization and blue light photoresponses of PAS and LOV domains of Neurospora crassa white collar proteins. Mol. Microbiol. 29 (1998) 719-729
8. Bell-Pedersen D., Dunlap J.C., and Loros J.J. Distinct cis-acting elements mediate clock, light, and developmental regulation of the Neurospora crassa eas(ccg-2) gene. Mol. Cell. Biol. 16 (1996) 513-521
9. Bell-Pedersen D., Shinohara M., Loros J., and Dunlap J.C. Circadian clock-controlled genes isolated from Neurospora crassa are late night to early morning specific. Proc. Natl. Acad. Sci. USA 93 (1996) 13096-13101
10. Bell-Pedersen D., Lewis Z.A., Loros J.J., and Dunlap J.C. The Neurospora circadian clock regulates a transcription factor that controls rhythmic expression of the output eas(ccg-2) gene. Mol. Microbiol. 41 (2001) 897-909
11. Bell-Pedersen D., Cassone V.M., Earnest D.J., Golden S.S., Hardin P.E., Thomas T.L., and Zoran M.J. Circadian rhythms from multiple oscillators: Lessons from diverse organisms. Nat. Rev. Genet. 6 (2005) 544-556
12. Borkovich K.A., Alex L.A., Yarden O., Freitag M., Turner G.E., Read N.D., Seiler S., Bell-Pedersen D., Paietta J., Plesofsky N., Plamann M., Goodrich-Tanrikulu M., et al. Lessons from the genome sequence of Neurospora crassa: Tracing the path from genomic blueprint to multicellular organism. Microbiol. Mol. Biol. Rev. 68 (2004) 1-108
13. Brown S.A., Ripperger J., Kadener S., Fleury-Olela F., Vilbois F., Rosbash M., and Schibler U. PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator. Science 308 (2005) 693-696
14. Bünning E. Die endogene Tagesrhythmik als Grundlage der photoperiodischen Reaktion. Ber. Dtsch. Bot. Ges. 54 (1936) 590-607
15. Carattoli A., Cogoni C., Morelli G., and Macino G. Molecular characterization of upstream regulatory sequences controlling the photoinduced expression of the albino-3 gene of Neurospora crassa. Mol. Microbiol. 13 (1994) 787-795
16. Cheng P., Yang Y., Heintzen C., and Liu Y. Coiled-coil domain mediated FRQ-FRQ interaction is essential for its circadian clock function in Neurospora. EMBO J. 20 (2001) 101-108
17. Cheng P., Yang Y., and Liu Y. Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock. Proc. Natl. Acad. Sci. USA 98 (2001) 7408-7413
18. Cheng P., Yang Y., Gardner K.H., and Liu Y. PAS domain-mediated WC-1/WC-2 interaction is essential for maintaining the steady state level of WC-1 and the function of both proteins in circadian clock and light responses of Neurospora. Mol. Cell. Biol. 22 (2002) 517-524
19. Cheng P., He Q., Yang Y., Wang L., and Liu Y. Functional conservation of light, oxygen, or voltage domains in light sensing. Proc. Natl. Acad. Sci. USA 100 (2003) 5938-5943
20. Cheng P., Yang Y., Wang L., He Q., and Liu Y. WHITE COLLAR-1, a multifunctional Neurospora protein involved in the circadian feedback loops, light sensing, and transcription repression of wc-2. J. Biol. Chem. 278 (2003) 3801-3808
21. Cheng P., He Q., He Q., Wang L., and Liu Y. Regulation of the Neurospora circadian clock by an RNA helicase. Genes Dev. 19 (2005) 234-241
22. Christensen M.K., Falkeid G., Loros J.J., Dunlap J.C., Lillo C., and Ruoff P. A nitrate-induced frq-less oscillator in Neurospora crassa. J. Biol. Rhythms 19 (2004) 280-286
23. Collett M.A., Garceau N., Dunlap J.C., and Loros J.J. Light and clock expression of the Neurospora clock gene frequency is differentially driven by but dependent on WHITE COLLAR-2. Genetics 160 (2002) 149-158
24. Colot H.V., Loros J.J., and Dunlap J.C. Temperature-modulated alternative splicing and promoter use in the circadian clock gene frequency. Mol. Biol. Cell 16 (2005) 5563-5571
25. Colot H.V., Park G., Turner G.E., Ringelberg C., Crew C., Litvinkova L., Weiss R.L., Borkovich K.A., and Dunlap J.C. A high throughput gene knockout procedure for Neurospora reveals functions for multiple transcription factors. Proc. Natl. Acad. Sci. USA 103 (2006) 10352-10357
26. Correa A., Lewis A.Z., Greene A.V., March I.J., Gomer R.H., and Bell-Pedersen D. Multiple oscillators regulate circadian gene expression in Neurospora. Proc. Natl. Acad. Sci. USA 100 (2003) 13597-13602
27. Crosson S., and Moffat K. Structure of a flavin-binding plant photoreceptor domain: Insights into light-mediated signal transduction. Proc. Natl. Acad. Sci. USA 98 (2001) 2995-3000
28. Crosson S., and Moffat K. Photoexcited structure of a plant photoreceptor domain reveals a light-driven molecular switch. Plant Cell 14 (2002) 1067-1075
29. Crosson S., Rajagopal S., and Moffat K. The LOV domain family: Photoresponsive signaling modules coupled to diverse output domains. Biochemistry 42 (2003) 2-10
30. Crosthwaite S.K. Circadian clocks and natural antisense RNA. FEBS Lett. 567 (2004) 49-54
31. Crosthwaite S.K., Loros J.J., and Dunlap J.C. Light-induced resetting of a circadian clock is mediated by a rapid increase in frequency transcript. Cell 81 (1995) 1003-1012
32. Crosthwaite S.K., Dunlap J.C., and Loros J.J. Neurospora wc-1 and wc-2: Transcription, photoresponses, and the origins of circadian rhythmicity. Science 276 (1997) 763-769
33. de la Cruz J., Kressler D., Tollervey D., and Linder P. Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3′ end formation of 5.8S rRNA in Saccharomyces cerevisiae. EMBO J. 17 (1998) 1128-1140
34. Denault D.L., Loros J.J., and Dunlap J.C. WC-2 mediates WC-1-FRQ interaction within the PAS protein-linked circadian feedback loop of Neurospora. EMBO J. 20 (2001) 109-117
35. Diernfellner A.C., Schafmeier T., Merrow M.W., and Brunner M. Molecular mechanism of temperature sensing by the circadian clock of Neurospora crassa. Genes Dev. 19 (2005) 1968-1973
36. Dragovic Z., Tan Y., Gorl M., Roenneberg T., and Merrow M. Light reception and circadian behavior in 'blind' and 'clock-less' mutants of Neurospora crassa. EMBO J. 21 (2002) 3643-3651
37. Dunlap J.C. Molecular bases for circadian clocks. Cell 96 (1999) 271-290
38. Dunlap J.C., and Loros J.J. The Neurospora circadian system. J. Biol. Rhythms 19 (2004) 414-424
39. Dunlap J.C., and Loros J.J. Analysis of circadian rhythms in Neurospora: Overview of assays and genetic and molecular biological manipulation. Methods Enzymol. 393 (2005) 3-22
40. Dunlap J.C., Loros J.J., and DeCoursey P.J. "Chronobiology." (2004), Sinauer Associates Inc., Publishers, Sunderland
41. Eide E.J., Woolf M.F., Kang H., Woolf P., Hurst W., Camacho F., Vielhaber E.L., Giovanni A., and Virshup D.M. Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation. Mol. Cell. Biol. 25 (2005) 2795-2807
42. Elvin M., Loros J., Dunlap J.C., and Heintzen C. The PAS/LOV protein VIVID supports a rapidly dampened daytime oscillator that facilitates entrainment of the Neurospora circadian clock. Genes Dev. 19 (2005) 2593-2605
43. Feldman J.F., and Hoyle M. Isolation of circadian clock mutants of Neurospora crassa. Genetics 75 (1973) 605-613
44. Fleissner G., and Fleissner G. Feedback loops in the circadian system. In: Zatz M. (Ed). "Circadian Rhythms" (1992), Elsevier, Amsterdam 79-84
45. Franchi L., Fulci V., and Macino G. Protein kinase C modulates light responses in Neurospora by regulating the blue light photoreceptor WC-1. Mol. Microbiol. 56 (2005) 334-345
46. Froehlich A.C., Liu Y., Loros J.J., and Dunlap J.C. WHITE COLLAR-1, a circadian blue light photoreceptor, binding to the frequency promoter. Science 297 (2002) 815-819
47. Froehlich A.C., Loros J.J., and Dunlap J.C. Rhythmic binding of a WHITE COLLAR-containing complex to the frequency promoter is inhibited by FREQUENCY. Proc. Natl. Acad. Sci. USA 100 (2003) 5914-5919
48. Froehlich A.C., Noh B., Vierstra R.D., Loros J.J., and Dunlap J.C. Genetic and molecular analysis of phytochromes from the filamentous fungus Neurospora crassa. Eukaryotic Cell 4 (2005) 2140-2152
49. Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D., FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T., et al. The genome sequence of the filamentous fungus Neurospora crassa. Nature 422 (2003) 859-868
50. Garceau N., Liu Y., Loros J.J., and Dunlap J.C. Alternative initiation of translation and time-specific phosphorylation yield multiple forms of the essential clock protein FREQUENCY. Cell 89 (1997) 469-476
51. Gehring W., and Rosbash M. The coevolution of blue-light photoreception and circadian rhythms. J. Mol. Evol. 57 (2003) S286-S289
52. Gillette M.U., and Mitchell J.W. Signaling in the suprachiasmatic nucleus: Selectively responsive and integrative. Cell Tissue Res. 309 (2002) 99-107
53. Glossop N.R., Lyons L.C., and Hardin P.E. Interlocked feedback loops within the Drosophila circadian oscillator. Science 286 (1999) 766-768
54. Golden S.S. Timekeeping in bacteria: The cyanobacterial circadian clock. Curr. Opin. Microbiol. 6 (2003) 535-540
55. Gooch V.D. Effects of light and temperature steps on circadian rhythms of Neurospora crassa and Gonyaulax polyedra. In: Jaeger N.I. (Ed). "Temporal Order" (1985), Springer-Verlag, New York 232-237
56. Gooch V.D., Freeman L., and Lakin-Thomas P.L. Time-lapse analysis of the circadian rhythms of conidiation and growth rate in Neurospora. J. Biol. Rhythms 19 (2004) 493-503
57. Gorl M., Merrow M., Huttner B., Johnson J., Roenneberg T., and Brunner M. A PEST-like element in FREQUENCY determines the length of the circadian period in Neurospora crassa. EMBO J. 20 (2001) 7074-7084
58. 10, wc-1, and wc-2. J. Biol. Rhythms 18 (2003) 287-296
59. Grima B., Lamouroux A., Chelot E., Papin C., Limbourg-Bouchon B., and Rouyer F. The F-box protein slimb controls the levels of clock proteins period and timeless. Nature 420 (2002) 178-182
60. Harper S.M., Neil L.C., and Gardner K.H. Structural basis of a phototropin light switch. Science 301 (2003) 1541-1544
61. He Q., and Liu Y. Molecular mechanism of light responses in Neurospora: From light-induced transcription to photoadaptation. Genes Dev. 19 (2005) 2888-2899
62. He Q., Cheng P., Yang Y., Wang L., Gardner K.H., and Liu Y. WHITE COLLAR-1, a DNA binding transcription factor and a light sensor. Science 297 (2002) 840-843
63. He Q., Cheng P., Yang Y., He Q., Yu H., and Liu Y. FWD1-mediated degradation of FREQUENCY in Neurospora establishes a conserved mechanism for circadian clock regulation. EMBO J. 22 (2003) 4421-4430
64. He Q., Cheng P., He Q.Y., and Liu Y. The COP9 signalosome regulates the Neurospora circadian clock by controlling the stability of the SCFFWD-1 complex. Genes Dev. 19 (2005) 1518-1531
65. He Q., Shu H., Cheng P., Chen S., Wang L., and Liu Y. Light-independent phosphorylation of WHITE COLLAR-1 regulates its function in the Neurospora circadian negative feedback loop. J. Biol. Chem. 280 (2005) 17526-17532
66. He Q., Cha J., Lee H., Yang Y., and Liu Y. CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loop. Genes & Dev. 20 (2006) 2252-2565
67. Heintzen C. PAS proteins and the Neurospora circadian clock. In: Kippert F. (Ed). "The Circadian Clock in Eukaryotic Microbes" (2005), Landes/Eurekah Bioscience, Austin
68. Heintzen C., Nater M., Apel K., and Staiger D. AtGRP7, a nuclear RNA-binding protein as a component of a circadian-regulated negative feedback loop in Arabidopsis thaliana. Proc. Natl. Acad. Sci. USA 94 (1997) 8515-8520
69. Heintzen C., Loros L.L., and Dunlap J.C. The PAS protein VIVID defines a clock-associated feedback loop that represses light input, modulates gating and regulates clock resetting. Cell 104 (2001) 453-464
70. Hilleren P.J., and Parker R. Cytoplasmic degradation of splice-defective pre-mRNAs and intermediates. Mol. Cell 12 (2003) 1453-1465
71. Huang G., Wang L., and Liu Y. Molecular mechanism of suppression of circadian rhythm by a critical stimulus. EMBO J. 25 (2006) 5349-5357
72. Imaizumi T., Tran H.G., Swartz T.E., Briggs W.R., and Kay S.A. FKF1 is essential for photoperiodic-specific light signalling in Arabidopsis. Nature 426 (2003) 302-306
73. Imaizumi T., Schultz T.F., Harmon F.G., Ho L.A., and Kay S.A. FKF1F-BOX protein mediates cyclic degradation of a repressor of CONSTANS in Arabidopsis. Science 309 (2005) 293-297
74. Iwasaki H., and Dunlap J.C. Microbial circadian oscillatory systems in Neurospora and Drosophila: Models for cellular clocks. Curr. Opin. Microbiol. 3 (2000) 189-196
75. Jacobs J.S., Anderson A.R., and Parker R.P. The 3′ to 5′ degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3′ to 5′ exonucleases of the exosome complex. EMBO J. 17 (1998) 1497-1506
76. Johnson C.H., Elliott J.A., and Foster R. Entrainment of circadian programs. Chronobiol. Int. 20 (2003) 741-774
77. Johnson C.H., Elliott J., Foster R., Honma K., and Kronauer R.E. Fundamental properties of circadian rhythms. In: Dunlap J.C., Loros J.J., and DeCoursey P.J. (Eds). "Chronobiology" (2004), Sinauer Associates Inc., Publishers, Sunderland
78. Kim E.Y., Bae K., Ng F.S., Glossop N.R., Hardin P.E., and Edery I. Drosophila CLOCK protein is under posttranscriptional control and influences light-induced activity. Neuron 34 (2002) 69-81
79. Kloss B., Price J.L., Saez L., Blau J., Rothenfluh A., and Young M.W. The Drosophila clock gene double-time encodes a protein closely related to human casein kinase Iε. Cell 94 (1998) 97-107
80. Ko H.W., Jiang J., and Edery I. Role for Slimb in the degradation of Drosophila period protein phosphorylated by Doubletime. Nature 420 (2002) 673-678
81. Kramer C., Loros J.J., Dunlap J.C., and Crosthwaite S.K. Role for antisense RNA in regulating circadian clock function in Neurospora crassa. Nature 421 (2003) 948-952
82. Krishnan B., Levine J.D., Lynch M.K., Dowse H.B., Funes P., Hall J.C., Hardin P.E., and Dryer S.E. A new role for cryptochrome in a Drosophila circadian oscillator. Nature 411 (2001) 313-317
83. Lakin-Thomas P.L., and Brody S. Circadian rhythms in Neurospora crassa: Lipid deficiencies restore robust rhythmicity to null frequency and white-collar mutants. Proc. Natl. Acad. Sci. USA 97 (2000) 256-261
84. Lakin-Thomas P.L., and Brody S. Circadian rhythms in microorganisms: New complexities. Annu. Rev. Microbiol. 58 (2004) 489-519
85. Lee K., Loros J.J., and Dunlap J.C. Interconnected feedback loops in the Neurospora circadian system. Science 289 (2000) 107-110
86. Lewis Z.A., Correa A., Schwerdtfeger C., Link K.L., Xie X., Gomer R.H., Thomas T., Ebbole D.J., and Bell-Pedersen D. Overexpression of WHITE COLLAR-1 (WC-1) activates circadian clock-associated genes, but is not sufficient to induce most light-regulated gene expression in Neurospora crassa. Mol. Microbiol. 45 (2002) 917-931
87. Lin J.M., Kilman V.L., Keegan K., Paddock B., Emery-Le M., Rosbash M., and Allada R. A role for casein kinase 2alpha in the Drosophila circadian clock. Nature 420 (2002) 816-820
88. Linden H. Circadian rhythms: A WHITE COLLAR protein senses blue light. Science 297 (2002) 777-778
89. Linden H., and Macino G. White collar-2, a partner in blue-light signal transduction, controlling expression of light-regulated genes in Neurospora crassa. EMBO J. 16 (1997) 98-109
90. Linden H., Ballario P., Arpaia G., and Macino G. Seeing the light: News in Neurospora blue light signal transduction. Adv. Genet. 37 (1999) 35-54
91. Liu Y. Molecular mechanisms of entrainment in the Neurospora circadian clock. J. Biol. Rhythms 18 (2003) 195-205
92. Liu Y. Analysis of posttranslational regulations in the Neurospora circadian clock. Methods Enzymol. 393 (2005) 379-393
93. Liu Y., Garceau N., Loros J.J., and Dunlap J.C. Thermally regulated translational control mediates an aspect of temperature compensation in the Neurospora circadian clock. Cell 89 (1997) 477-486
94. Liu Y., Merrow M.M., Loros J.J., and Dunlap J.C. How temperature changes reset a circadian oscillator. Science 281 (1998) 825-829
95. Liu Y., Loros J., and Dunlap J.C. Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock. Proc. Natl. Acad. Sci. USA 97 (2000) 234-239
96. Liu Y., He Q., and Cheng P. Photoreception in Neurospora: A tale of two WHITE COLLAR proteins. Cell. Mol. Life Sci. 60 (2003) 2131-2138
97. Loros J.J., and Feldman J.F. Loss of temperature compensation of circadian period length in the frq-9 mutant of Neurospora crassa. J. Biol. Rhythms 1 (1986) 187-198
98. Loros J.J., and Dunlap J.C. Genetic and molecular analysis of circadian rhythms in Neurospora. Annu. Rev. Physiol. 63 (2001) 757-794
99. Loros J.J., Richman A., and Feldman J.F. A recessive circadian clock mutant at the frq locus in Neurospora crassa. Genetics 114 (1986) 1095-1110
100. Loros J.J., Denome S.A., and Dunlap J.C. Molecular cloning of genes under the control of the circadian clock in Neurospora. Science 243 (1989) 385-388
101. Lowrey P.L., Shimomura K., Antoch M.P., Yamazaki S., Zemenides P.D., Ralph M.R., Menaker M., and Takahashi J.S. Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau. Science 288 (2000) 483-492
102. Luo C., Loros J.J., and Dunlap J.C. Nuclear localization is required for function of the essential clock protein FREQUENCY. EMBO J. 17 (1998) 1228-1235
103. Martinek S., Inonog S., Manoukian A.S., and Young M.W. A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock. Cell 105 (2001) 769-779
104. Mattern D., and Brody S. Circadian rhythms in Neurospora crassa: Effects of unsaturated fatty acids. J. Bacteriol. 139 (1979) 977-988
105. McClung C.R., Fox B.A., and Dunlap J.C. The Neurospora clock gene frequency shares a sequence element with the Drosophila clock gene period. Nature 339 (1989) 558-562
106. McWatters H.G., Bastow R.M., Hall A., and Millar A.J. The ELF3 zeitnehmer regulates light signalling to the circadian clock. Nature 408 (2000) 716-720
107. Merrow M., Garceau N., and Dunlap J.C. Dissection of a circadian oscillation into discrete domains. Proc. Natl. Acad. Sci. USA 94 (1997) 3877-3882
108. Merrow M., Brunner M., and Roenneberg T. Assignment of circadian function for the Neurospora clock gene frequency. Nature 399 (1999) 584-586
109. Merrow M., Franchi L., Dragovic Z., Gorl M., Johnson J., Brunner M., Macino G., and Roenneberg T. Circadian regulation of the light input pathway in Neurospora crassa. EMBO J. 20 (2001) 307-315
110. Millar A.J., and Kay S.A. Integration of circadian and phototransduction pathways in the network controlling CAB gene transcription in Arabidopsis. Proc. Natl. Acad. Sci. USA 93 (1996) 15491-15496
111. Mitchell P., and Tollervey D. Musing on the structural organization of the exosome complex. Nat. Struct. Biol. 7 (2000) 843-846
112. Morgan L.W., Greene A.V., and Bell-Pedersen D. Circadian and light-induced expression of luciferase in Neurospora crassa. Fungal Genet. Biol. 38 (2003) 327-332
113. Nakajima M., Imai K., Ito H., Nishiwaki T., Murayama Y., Iwasaki T., Oyama T., and Kondo T. Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro. Science 308 (2005) 414-415
114. Nawathean P., and Rosbash M. The doubletime and CKII kinases collaborate to potentiate Drosophila PER transcriptional repressor activity. Mol. Cell 13 (2004) 213-223
115. Nowrousian M., Duffield G.E., Loros J.J., and Dunlap J.C. The frequency gene is required for temperature-dependent regulation of many clock-controlled genes in Neurospora crassa. Genetics 164 (2003) 923-933
116. Ouyang Y., Andersson C.R., Kondo T., Golden S.S., and Johnson C.H. Resonating circadian clocks enhance fitness in cyanobacteria. Proc. Natl. Acad. Sci. USA 95 (1998) 8660-8664
117. Pittendrigh C.S. Circadian rhythms and the circadian organization of living things. In: Chovnick A. (Ed). "Cold Spring Harbor Symp. Quant. Biol. XXV: Biological Clocks" (1960), Cold Spring Harbor Press, New York 159-184
118. Pregueiro A.M., Price-Lloyd N., Bell-Pedersen D., Heintzen C., Loros J.J., and Dunlap J.C. Assignment of an essential role for the Neurospora frequency gene in circadian entrainment to temperature cycles. Proc. Natl. Acad. Sci. USA 102 (2005) 2210-2215
119. Preitner N., Damiola F., Luis-Lopez M., Zakany J., Duboule D., Albrecht U., and Schibler U. The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator. Cell 110 (2002) 251-260
120. Price J.L., Blau J., Rothenfluh A., Adodeely M., Kloss B., and Young M.W. Double-time is a new Drosophila clock gene that regulates PERIOD protein accumulation. Cell 94 (1998) 83-95
121. Roenneberg T., and Merrow M. Seasonality and photoperiodism in fungi. J. Biol. Rhythms 16 (2001) 403-414
122. Roenneberg T., Daan S., and Merrow M. The art of entrainment. J. Biol. Rhythms 18 (2003) 183-194
123. Roenneberg T., Dragovic Z., and Merrow M. Demasking biological oscillators: Properties and principles of entrainment exemplified by the Neurospora circadian clock. Proc. Natl. Acad. Sci. USA 102 (2005) 7742-7747
124. Sathyanarayanan S., Zheng X., Xiao R., and Sehgal A. Posttranslational regulation of Drosophila PERIOD protein by protein phosphatase 2A. Cell 116 (2004) 603-615
125. Saunders D.S. Erwin Bünning and Tony Lees, two giants of chronobiology, and the problem of time measurement in insect photoperiodism. J. Insect Physiol. 51 (2005) 599-608
126. Schafmeier T., Haase A., Kaldi K., Scholz J., Fuchs M., and Brunner M. Transcriptional feedback of a Neurospora circadian clock gene by phosphorylation-dependent inactivation of its transcription factor. Cell 122 (2005) 235-246
127. Schwerdtfeger C., and Linden H. Localization and light-dependent phosphorylation of white collar-1 and 2, the two central components of blue light signaling in Neurospora crassa. Eur. J. Biochem. 267 (2000) 414-422
128. Schwerdtfeger C., and Linden H. Blue light adaptation and desensitization of light signal transduction in Neurospora crassa. Mol. Microbiol. 39 (2001) 1080-1087
129. Schwerdtfeger C., and Linden H. VIVID is a flavoprotein and serves as a fungal blue light photoreceptor for photoadaptation. EMBO J. 22 (2003) 4846-4855
130. Shearman L.P., Sriram S., Weaver D.R., Maywood E.S., Chaves I., Zheng B., Kume K., Lee C.C., van der Horst G.T., Hastings M.H., and Reppert S.M. Interacting molecular loops in the mammalian circadian clock. Science 288 (2000) 1013-1019
131. Shigeyoshi Y., Taguchi K., Yamamoto S., Takeida S., Yan L., Tei H., Moriya S., Shibata S., Loros J.J., Dunlap J.C., and Okamura H. Light-induced resetting of a mammalian circadian clock is associated with rapid induction of the mPer1 transcript. Cell 91 (1997) 1043-1053
132. Shrode L.B., Lewis Z.A., White L.D., Bell-Pedersen D., and Ebbole D.J. vvd is required for light adaptation of conidiation-specific genes of Neurospora crassa, but not circadian conidiation. Fungal Genet. Biol. 32 (2001) 169-181
133. Staiger D., Zecca L., Kirk D.A.W., Apel K., and Eckstein L. The circadian clock regulated RNA-binding protein AtGRP7 autoregulates its expression by influencing alternative splicing of its own pre-mRNA. Plant J. 33 (2003) 361-371
134. Suarez-Lopez P., Wheatley K., Robson F., Onouchi H., Valverde F., and Coupland G. CONSTANS mediates between the circadian clock and the control of flowering in Arabidopsis. Nature 410 (2001) 1116-1120
135. Talora C., Franchi L., Linden H., Ballario P., and Macino G. Role of a WHITE COLLAR-1:WHITE COLLAR-2 complex in blue-light signal transduction. EMBO J. 18 (1999) 4961-4968
136. Tan Y., Dragovic Z., Roenneberg T., and Merrow M. Entrainment dissociates transcription and translation of a circadian clock gene in Neurospora. Curr. Biol. 14 (2004) 433-438
137. Tan Y., Merrow M., and Roenneberg T. Photoperiodism in Neurospora crassa. J. Biol. Rhythms 19 (2004) 135-143
138. Tauber E., Last K.S., Olive P.J., and Kyriacou C.P. Clock gene evolution and functional divergence. J. Biol. Rhythms 19 (2004) 445-458
139. Tomita J., Nakajima M., Kondo T., and Iwasaki H. No transcription-translation feedback in circadian rhythm of KaiC phosphorylation. Science 307 (2005) 251-254
140. Torchet C., Bousquet-Antonelli C., Milligan L., Thompson E., Kufel J., and Tollervey D. Processing of 3′-extended read-through transcripts by the exosome can generate functional mRNAs. Mol. Cell 9 (2002) 1285-1296
141. Valverde F., Mouradov A., Soppe W., Ravenscroft D., Samach A., and Coupland G. Photoreceptor regulation of CONSTANS protein in photoperiodic flowering. Science 303 (2004) 1003-1006
142. Vitalini M.W., Morgan L.W., March I.J., and Bell-Pedersen D. A genetic selection for circadian output pathway mutations in Neurospora crassa. Genetics 167 (2004) 119-129
143. Xu Y., Padiath Q.S., Shapiro R.E., Jones C.R., Wu S.C., Saigoh N., Saigoh K., Ptacek L.J., and Fu Y.H. Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome. Nature 434 (2005) 640-644
144. Yang Y., Cheng P., Zhi G., and Liu Y. Identification of a calcium/calmodulin-dependent protein kinase that phosphorylates the Neurospora circadian clock protein FREQUENCY. J. Biol. Chem. 276 (2001) 41064-41072
145. Yang Y., Cheng P., and Liu Y. Regulation of the Neurospora circadian clock by CASEIN KINASE II. Genes Dev. 16 (2002) 994-1006
146. Yang Y., Cheng P., He Q., Wang L., and Liu Y. Phosphorylation of FREQUENCY protein by CASEIN KINASE II is necessary for the function of the Neurospora circadian clock. Mol. Cell. Biol. 23 (2003) 6221-6228
147. Yang Y., He Q., Cheng P., Wrage P., Yarden O., and Liu Y. Distinct roles for PP1 and PP2A in the Neurospora circadian clock. Genes Dev. 18 (2004) 255-260
148. Yanovsky M.J., and Kay S.A. Molecular basis of seasonal time measurement in Arabidopsis. Nature 419 (2002) 308-312
149. Young M.W., and Kay S.A. Time zones: A comparative genetics of circadian clocks. Nat. Rev. Genet. 2 (2001) 702-715