메뉴 건너뛰기




Volumn 8, Issue , 2008, Pages 698-712

New targets of neuroprotection in ischemic stroke

Author keywords

Animal models; Neuroprotection; Neurorestoration; Pathophysiology; Reperfusion; Stroke

Indexed keywords

ERYTHROPOIETIN; ESTROGEN; GELATINASE B; GRANULOCYTE COLONY STIMULATING FACTOR; MELATONIN; MINOCYCLINE; MULTIDRUG RESISTANCE PROTEIN 1; NEUROPROTECTIVE AGENT; NOGO A ANTIBODY; OXYGEN; PROTEIN NOGO A; TISSUE PLASMINOGEN ACTIVATOR; VASCULOTROPIN;

EID: 47349088595     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1100/tsw.2008.94     Document Type: Review
Times cited : (19)

References (146)
  • 1
    • 34547799633 scopus 로고    scopus 로고
    • Stroke treatment - light at the end of the tunnel?
    • Garber, K. (2007) Stroke treatment - light at the end of the tunnel? Nat. Biotechnol. 25, 838-840.
    • (2007) Nat. Biotechnol , vol.25 , pp. 838-840
    • Garber, K.1
  • 2
    • 0344065373 scopus 로고    scopus 로고
    • Recommendations for standards regarding preclinical neuroprotective and restorative drug development. Stroke 30, 2752-2758
    • (1999) Recommendations for standards regarding preclinical neuroprotective and restorative drug development. Stroke 30, 2752-2758.
  • 3
    • 0037126011 scopus 로고    scopus 로고
    • Treatment of acute ischemic stroke: Part I: recanalization strategies
    • Broderick, J.P. and Hacke, W. (2002) Treatment of acute ischemic stroke: Part I: recanalization strategies. Circulation 106, 1563-1569.
    • (2002) Circulation , vol.106 , pp. 1563-1569
    • Broderick, J.P.1    Hacke, W.2
  • 4
    • 34249942190 scopus 로고    scopus 로고
    • Future of neuroprotection for acute stroke: In the aftermath of the SAINT trials
    • Savitz, S.I. and Fisher, M. (2007) Future of neuroprotection for acute stroke: in the aftermath of the SAINT trials. Ann. Neurol. 61, 396-402.
    • (2007) Ann. Neurol , vol.61 , pp. 396-402
    • Savitz, S.I.1    Fisher, M.2
  • 5
    • 36448933286 scopus 로고    scopus 로고
    • Neuroprotection in the SAINT-II aftermath
    • author reply 678
    • Hermann, D.M. and Bassetti, C.L. (2007) Neuroprotection in the SAINT-II aftermath. Ann. Neurol. 62(6), 677-678; author reply 678.
    • (2007) Ann. Neurol , vol.62 , Issue.6 , pp. 677-678
    • Hermann, D.M.1    Bassetti, C.L.2
  • 6
    • 33847139661 scopus 로고    scopus 로고
    • Implications of ATP-binding cassette transporters for brain pharmacotherapies
    • Hermann, D.M. and Bassetti, C.L. (2007) Implications of ATP-binding cassette transporters for brain pharmacotherapies. Trends Pharmacol. Sci. 28, 128-134.
    • (2007) Trends Pharmacol. Sci , vol.28 , pp. 128-134
    • Hermann, D.M.1    Bassetti, C.L.2
  • 8
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: An integrated view
    • Dirnagl, U., Iadecola, C., and Moskowitz, M.A. (1999) Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci. 22, 391-397.
    • (1999) Trends Neurosci , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 9
    • 33845547792 scopus 로고    scopus 로고
    • Pathophysiology and therapy of experimental stroke
    • Hossmann, K.A. (2006) Pathophysiology and therapy of experimental stroke. Cell. Mol. Neurobiol. 26, 1057-1083.
    • (2006) Cell. Mol. Neurobiol , vol.26 , pp. 1057-1083
    • Hossmann, K.A.1
  • 10
    • 0034119985 scopus 로고    scopus 로고
    • Evolution of brain infarction after transient focal cerebral ischemia in mice
    • Hata, R., Maeda, K., Hermann, D., Mies, G., and Hossmann, K.A. (2000) Evolution of brain infarction after transient focal cerebral ischemia in mice. J. Cereb. Blood Flow Metab. 20, 937-946.
    • (2000) J. Cereb. Blood Flow Metab , vol.20 , pp. 937-946
    • Hata, R.1    Maeda, K.2    Hermann, D.3    Mies, G.4    Hossmann, K.A.5
  • 11
    • 0033964104 scopus 로고    scopus 로고
    • Dynamics of regional brain metabolism and gene expression after middle cerebral artery occlusion in mice
    • Hata, R., Maeda, K., Hermann, D., Mies, G., and Hossmann, K.A. (2000) Dynamics of regional brain metabolism and gene expression after middle cerebral artery occlusion in mice. J. Cereb. Blood Flow Metab. 20, 306-315.
    • (2000) J. Cereb. Blood Flow Metab , vol.20 , pp. 306-315
    • Hata, R.1    Maeda, K.2    Hermann, D.3    Mies, G.4    Hossmann, K.A.5
  • 12
    • 0025950408 scopus 로고
    • Ischemic thresholds of cerebral protein synthesis and energy state following middle cerebral artery occlusion in rat
    • Mies, G., Ishimaru, S., Xie, Y., Seo, K., and Hossmann, K.A. (1991) Ischemic thresholds of cerebral protein synthesis and energy state following middle cerebral artery occlusion in rat. J. Cereb. Blood Flow Metab. 11, 753-761.
    • (1991) J. Cereb. Blood Flow Metab , vol.11 , pp. 753-761
    • Mies, G.1    Ishimaru, S.2    Xie, Y.3    Seo, K.4    Hossmann, K.A.5
  • 14
    • 33745478859 scopus 로고    scopus 로고
    • Mechanisms of neural plasticity following brain injury
    • Wieloch, T. and Nikolich, K. (2006) Mechanisms of neural plasticity following brain injury. Curr. Opin. Neurobiol. 16, 258-264.
    • (2006) Curr. Opin. Neurobiol , vol.16 , pp. 258-264
    • Wieloch, T.1    Nikolich, K.2
  • 15
    • 33746271855 scopus 로고    scopus 로고
    • Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury?
    • Harel, N.Y. and Strittmatter, S.M. (2006) Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury? Nat. Rev. 7, 603-616.
    • (2006) Nat. Rev , vol.7 , pp. 603-616
    • Harel, N.Y.1    Strittmatter, S.M.2
  • 16
    • 0037083631 scopus 로고    scopus 로고
    • Small proline-rich repeat protein 1A is expressed by axotomized neurons and promotes axonal outgrowth
    • Bonilla, I.E., Tanabe, K., and Strittmatter, S.M. (2002) Small proline-rich repeat protein 1A is expressed by axotomized neurons and promotes axonal outgrowth. J. Neurosci. 22, 1303-1315.
    • (2002) J. Neurosci , vol.22 , pp. 1303-1315
    • Bonilla, I.E.1    Tanabe, K.2    Strittmatter, S.M.3
  • 17
    • 0031959973 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression increases after cerebral focal ischemia in rats: Inhibition of matrix metalloproteinase-9 reduces infarct size
    • Romanic, A.M., White, R.F., Arleth, A.J., Ohlstein, E.H., and Barone, F.C. (1998) Matrix metalloproteinase expression increases after cerebral focal ischemia in rats: inhibition of matrix metalloproteinase-9 reduces infarct size. Stroke 29, 1020-1030.
    • (1998) Stroke , vol.29 , pp. 1020-1030
    • Romanic, A.M.1    White, R.F.2    Arleth, A.J.3    Ohlstein, E.H.4    Barone, F.C.5
  • 18
    • 0033638508 scopus 로고    scopus 로고
    • Role for matrix metalloproteinase 9 after focal cerebral ischemia: Effects of gene knockout and enzyme inhibition with BB-94
    • Asahi, M., Asahi, K., Jung, J.C., del Zoppo, G.J., Fini, M.E., and Lo, E.H. (2000) Role for matrix metalloproteinase 9 after focal cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94. J. Cereb. Blood Flow Metab. 20, 1681-1689.
    • (2000) J. Cereb. Blood Flow Metab , vol.20 , pp. 1681-1689
    • Asahi, M.1    Asahi, K.2    Jung, J.C.3    del Zoppo, G.J.4    Fini, M.E.5    Lo, E.H.6
  • 20
    • 43249116466 scopus 로고    scopus 로고
    • A new penumbra: Transitioning from injury into repair after stroke
    • Lo, E.H. (2008) A new penumbra: transitioning from injury into repair after stroke. Nat. Med. 14, 497-500.
    • (2008) Nat. Med , vol.14 , pp. 497-500
    • Lo, E.H.1
  • 21
    • 26844435654 scopus 로고    scopus 로고
    • Rodent models of focal stroke: Size, mechanism, and purpose
    • Carmichael, S.T. (2005) Rodent models of focal stroke: size, mechanism, and purpose. NeuroRx 2, 396-409.
    • (2005) NeuroRx , vol.2 , pp. 396-409
    • Carmichael, S.T.1
  • 22
    • 0026795049 scopus 로고
    • Middle cerebral artery occlusion in rats: A neurological and pathological evaluation of a reproducible model
    • discussion 106-107
    • Menzies, S.A., Hoff, J.T., and Betz, A.L. (1992) Middle cerebral artery occlusion in rats: a neurological and pathological evaluation of a reproducible model. Neurosurgery 31, 100-106; discussion 106-107.
    • (1992) Neurosurgery , vol.31 , pp. 100-106
    • Menzies, S.A.1    Hoff, J.T.2    Betz, A.L.3
  • 24
    • 0035800010 scopus 로고    scopus 로고
    • Relationship between metabolic dysfunctions, gene responses and delayed cell death after mild focal cerebral ischemia in mice
    • Hermann, D.M., Kilic, E., Hata, R., Hossmann, K.A., and Mies, G. (2001) Relationship between metabolic dysfunctions, gene responses and delayed cell death after mild focal cerebral ischemia in mice. Neuroscience 104, 947-955.
    • (2001) Neuroscience , vol.104 , pp. 947-955
    • Hermann, D.M.1    Kilic, E.2    Hata, R.3    Hossmann, K.A.4    Mies, G.5
  • 25
    • 0030664096 scopus 로고    scopus 로고
    • Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene
    • Iadecola, C., Zhang, F., Casey, R., Nagayama, M., and Ross, M.E. (1997) Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene. J. Neurosci. 17, 9157-9164.
    • (1997) J. Neurosci , vol.17 , pp. 9157-9164
    • Iadecola, C.1    Zhang, F.2    Casey, R.3    Nagayama, M.4    Ross, M.E.5
  • 26
    • 0026508278 scopus 로고
    • A new model of temporary focal neocortical ischemia in the rat
    • Buchan, A.M., Xue, D., and Slivka, A. (1992) A new model of temporary focal neocortical ischemia in the rat. Stroke 23, 273-279.
    • (1992) Stroke , vol.23 , pp. 273-279
    • Buchan, A.M.1    Xue, D.2    Slivka, A.3
  • 27
    • 0021826450 scopus 로고
    • Induction of reproducible brain infarction by photochemically initiated thrombosis
    • Watson, B.D., Dietrich, W.D., Busto, R., Wachtel, M.S., and Ginsberg, M.D. (1985) Induction of reproducible brain infarction by photochemically initiated thrombosis. Ann. Neurol. 17, 497-504.
    • (1985) Ann. Neurol , vol.17 , pp. 497-504
    • Watson, B.D.1    Dietrich, W.D.2    Busto, R.3    Wachtel, M.S.4    Ginsberg, M.D.5
  • 28
    • 0037472778 scopus 로고    scopus 로고
    • The macrosphere model: Evaluation of a new stroke model for permanent middle cerebral artery occlusion in rats
    • Gerriets, T., Li, F., Silva, M.D., Meng, X., Brevard, M., Sotak, C.H., and Fisher, M. (2003) The macrosphere model: evaluation of a new stroke model for permanent middle cerebral artery occlusion in rats. J. Neurosci. Methods 122, 201-211.
    • (2003) J. Neurosci. Methods , vol.122 , pp. 201-211
    • Gerriets, T.1    Li, F.2    Silva, M.D.3    Meng, X.4    Brevard, M.5    Sotak, C.H.6    Fisher, M.7
  • 29
    • 0027405380 scopus 로고
    • Sustained decrease in brain regional blood flow after microsphere embolism in rats
    • Miyake, K., Takeo, S., and Kaijihara, H. (1993) Sustained decrease in brain regional blood flow after microsphere embolism in rats. Stroke 24, 415-420.
    • (1993) Stroke , vol.24 , pp. 415-420
    • Miyake, K.1    Takeo, S.2    Kaijihara, H.3
  • 30
    • 0032517104 scopus 로고    scopus 로고
    • A reproducible model of thromboembolic stroke in mice
    • Kilic, E., Hermann, D.M., and Hossmann, K.A. (1998) A reproducible model of thromboembolic stroke in mice. Neuroreport 9, 2967-2970.
    • (1998) Neuroreport , vol.9 , pp. 2967-2970
    • Kilic, E.1    Hermann, D.M.2    Hossmann, K.A.3
  • 31
    • 0033580092 scopus 로고    scopus 로고
    • Recombinant tissue plasminogen activator reduces infarct size after reversible thread occlusion of middle cerebral artery in mice
    • Kilic, E., Hermann, D.M., and Hossmann, K.A. (1999) Recombinant tissue plasminogen activator reduces infarct size after reversible thread occlusion of middle cerebral artery in mice. Neuroreport 10, 107-111.
    • (1999) Neuroreport , vol.10 , pp. 107-111
    • Kilic, E.1    Hermann, D.M.2    Hossmann, K.A.3
  • 32
    • 0032738822 scopus 로고    scopus 로고
    • Thrombolysis of cerebral clot embolism in rat: Effect of treatment delay
    • Brinker, G., Franke, C., Hoehn, M., Uhlenkuken, U., and Hossmann, K.A. (1999) Thrombolysis of cerebral clot embolism in rat: effect of treatment delay. Neuroreport 10, 3269-3272.
    • (1999) Neuroreport , vol.10 , pp. 3269-3272
    • Brinker, G.1    Franke, C.2    Hoehn, M.3    Uhlenkuken, U.4    Hossmann, K.A.5
  • 33
    • 0033597569 scopus 로고    scopus 로고
    • Brain hemorrhages after rt-PA treatment of embolic stroke in spontaneously hypertensive rats
    • Brinker, G., Pillekamp, F., and Hossmann, K.A. (1999) Brain hemorrhages after rt-PA treatment of embolic stroke in spontaneously hypertensive rats. Neuroreport 10, 1943-1946.
    • (1999) Neuroreport , vol.10 , pp. 1943-1946
    • Brinker, G.1    Pillekamp, F.2    Hossmann, K.A.3
  • 35
    • 0033953958 scopus 로고    scopus 로고
    • Recombinant tissue-plasminogen activator-induced thrombolysis after cerebral thromboembolism in mice
    • Kilic, E., Hermann, D.M., and Hossmann, K.A. (2000) Recombinant tissue-plasminogen activator-induced thrombolysis after cerebral thromboembolism in mice. Acta Neuropathol. 99, 219-222.
    • (2000) Acta Neuropathol , vol.99 , pp. 219-222
    • Kilic, E.1    Hermann, D.M.2    Hossmann, K.A.3
  • 36
    • 0033774733 scopus 로고    scopus 로고
    • Effect of thrombolysis on the dynamics of infarct evolution after clot embolism of middle cerebral artery in mice
    • Hara, T., Mies, G., and Hossmann, K.A. (2000) Effect of thrombolysis on the dynamics of infarct evolution after clot embolism of middle cerebral artery in mice. J. Cereb. Blood Flow Metab. 20, 1483-1491.
    • (2000) J. Cereb. Blood Flow Metab , vol.20 , pp. 1483-1491
    • Hara, T.1    Mies, G.2    Hossmann, K.A.3
  • 37
    • 0028783948 scopus 로고    scopus 로고
    • Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N. Engl. J. Med. 333, 1581-1587.
    • (1995) Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N. Engl. J. Med. 333, 1581-1587.
  • 38
    • 1542328963 scopus 로고    scopus 로고
    • An update on thrombolytic therapy for acute stroke
    • Schellinger, P.D., Kaste, M., and Hacke, W. (2004) An update on thrombolytic therapy for acute stroke. Curr. Opin. Neurol. 17, 69-77.
    • (2004) Curr. Opin. Neurol , vol.17 , pp. 69-77
    • Schellinger, P.D.1    Kaste, M.2    Hacke, W.3
  • 39
    • 34447128746 scopus 로고    scopus 로고
    • Thrombolysis with alteplase for acute ischemic stroke: Review of SITS-MOST and other Phase IV studies
    • Kulkens, S. and Hacke, W. (2007) Thrombolysis with alteplase for acute ischemic stroke: review of SITS-MOST and other Phase IV studies. Expert Rev. Neurother. 7, 783-788.
    • (2007) Expert Rev. Neurother , vol.7 , pp. 783-788
    • Kulkens, S.1    Hacke, W.2
  • 41
    • 34547565191 scopus 로고    scopus 로고
    • Tissue plasminogen activator-induced reperfusion injury after stroke revisited
    • Hermann, D.M. and Matter, C.M. (2007) Tissue plasminogen activator-induced reperfusion injury after stroke revisited. Circulation 116, 363-365.
    • (2007) Circulation , vol.116 , pp. 363-365
    • Hermann, D.M.1    Matter, C.M.2
  • 42
    • 0031951510 scopus 로고    scopus 로고
    • Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice
    • Wang, Y.F., Tsirka, S.E., Strickland, S., Stieg, P.E., Soriano, S.G., and Lipton, S.A. (1998) Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice. Nat. Med. 4, 228-231.
    • (1998) Nat. Med , vol.4 , pp. 228-231
    • Wang, Y.F.1    Tsirka, S.E.2    Strickland, S.3    Stieg, P.E.4    Soriano, S.G.5    Lipton, S.A.6
  • 43
    • 44349186010 scopus 로고    scopus 로고
    • Lopez-Atalaya, J.P., Roussel, B.D., Levrat, D., Parcq, J., Nicole, O., Hommet, Y., Benchenane, K., Castel, H., Leprince, J., To Van, D., Bureau, R., Rault, S., Vaudry, H., Petersen, K.U., Santos, J.S., Ali, C., and Vivien, D. (2008) Toward safer thrombolytic agents in stroke: molecular requirements for NMDA receptor-mediated neurotoxicity. J. Cereb. Blood Flow Metab. 28, 1212-1221.
    • Lopez-Atalaya, J.P., Roussel, B.D., Levrat, D., Parcq, J., Nicole, O., Hommet, Y., Benchenane, K., Castel, H., Leprince, J., To Van, D., Bureau, R., Rault, S., Vaudry, H., Petersen, K.U., Santos, J.S., Ali, C., and Vivien, D. (2008) Toward safer thrombolytic agents in stroke: molecular requirements for NMDA receptor-mediated neurotoxicity. J. Cereb. Blood Flow Metab. 28, 1212-1221.
  • 44
    • 12844276482 scopus 로고    scopus 로고
    • Aggravation of focal cerebral ischemia by tissue plasminogen activator is reversed by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor but does not depend on endothelial NO synthase
    • Kilic, E., Kilic, U., Matter, C.M., Luscher, T.F., Bassetti, C.L., and Hermann, D.M. (2005) Aggravation of focal cerebral ischemia by tissue plasminogen activator is reversed by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor but does not depend on endothelial NO synthase. Stroke 36, 332-336.
    • (2005) Stroke , vol.36 , pp. 332-336
    • Kilic, E.1    Kilic, U.2    Matter, C.M.3    Luscher, T.F.4    Bassetti, C.L.5    Hermann, D.M.6
  • 45
    • 33644874287 scopus 로고    scopus 로고
    • Multitargeted effects of statin-enhanced thrombolytic therapy for stroke with recombinant human tissue-type plasminogen activator in the rat
    • Zhang, L., Zhang, Z.G., Ding, G.L., Jiang, Q., Liu, X., Meng, H., Hozeska, A., Zhang, C., Li, L., Morris, D., Zhang, R.L., Lu, M., and Chopp, M. (2005) Multitargeted effects of statin-enhanced thrombolytic therapy for stroke with recombinant human tissue-type plasminogen activator in the rat. Circulation 112, 3486-3494.
    • (2005) Circulation , vol.112 , pp. 3486-3494
    • Zhang, L.1    Zhang, Z.G.2    Ding, G.L.3    Jiang, Q.4    Liu, X.5    Meng, H.6    Hozeska, A.7    Zhang, C.8    Li, L.9    Morris, D.10    Zhang, R.L.11    Lu, M.12    Chopp, M.13
  • 46
    • 0030932288 scopus 로고    scopus 로고
    • Characterizing the target of acute stroke therapy
    • Fisher, M. (1997) Characterizing the target of acute stroke therapy. Stroke 28, 866-872.
    • (1997) Stroke , vol.28 , pp. 866-872
    • Fisher, M.1
  • 47
    • 0034037673 scopus 로고    scopus 로고
    • Penumbral tissue alkalosis in focal cerebral ischemia: Relationship to energy metabolism, blood flow, and steady potential
    • Back, T., Hoehn, M., Mies, G., Busch, E., Schmitz, B., Kohno, K., and Hossmann, K.A. (2000) Penumbral tissue alkalosis in focal cerebral ischemia: relationship to energy metabolism, blood flow, and steady potential. Ann. Neurol. 47, 485-492.
    • (2000) Ann. Neurol , vol.47 , pp. 485-492
    • Back, T.1    Hoehn, M.2    Mies, G.3    Busch, E.4    Schmitz, B.5    Kohno, K.6    Hossmann, K.A.7
  • 48
    • 0028070926 scopus 로고
    • Prevention of periinfarct direct current shifts with glutamate antagonist NBQX following occlusion of the middle cerebral artery in the rat
    • Mies, G., Kohno, K., and Hossmann, K.A. (1994) Prevention of periinfarct direct current shifts with glutamate antagonist NBQX following occlusion of the middle cerebral artery in the rat. J. Cereb. Blood Flow Metab. 14, 802-807.
    • (1994) J. Cereb. Blood Flow Metab , vol.14 , pp. 802-807
    • Mies, G.1    Kohno, K.2    Hossmann, K.A.3
  • 49
    • 0037231768 scopus 로고    scopus 로고
    • New perspectives on developing acute stroke therapy
    • Fisher, M. and Ratan, R. (2003) New perspectives on developing acute stroke therapy. Ann. Neurol. 53, 10-20.
    • (2003) Ann. Neurol , vol.53 , pp. 10-20
    • Fisher, M.1    Ratan, R.2
  • 50
    • 33750626551 scopus 로고    scopus 로고
    • Neuroprotection: the end of an era? Lancet 368, 1548.
    • (2006) Neuroprotection: the end of an era? Lancet 368, 1548.
  • 52
    • 1542268981 scopus 로고    scopus 로고
    • For the long run: Maintaining germinal niches in the adult brain
    • Alvarez-Buylla, A. and Lim, D.A. (2004) For the long run: maintaining germinal niches in the adult brain. Neuron 41, 683-686.
    • (2004) Neuron , vol.41 , pp. 683-686
    • Alvarez-Buylla, A.1    Lim, D.A.2
  • 53
    • 33845656103 scopus 로고    scopus 로고
    • A neurovascular niche for neurogenesis after stroke
    • Ohab, J.J., Fleming, S., Blesch, A., and Carmichael, S.T. (2006) A neurovascular niche for neurogenesis after stroke. J. Neurosci. 26, 13007-13016.
    • (2006) J. Neurosci , vol.26 , pp. 13007-13016
    • Ohab, J.J.1    Fleming, S.2    Blesch, A.3    Carmichael, S.T.4
  • 54
    • 0033402469 scopus 로고    scopus 로고
    • Excitotoxicity, oxidative stress, and the neuroprotective potential of melatonin
    • Skaper, S.D., Floreani, M., Ceccon, M., Facci, L., and Giusti, P. (1999) Excitotoxicity, oxidative stress, and the neuroprotective potential of melatonin. Ann. N. Y. Acad. Sci. 890, 107-118.
    • (1999) Ann. N. Y. Acad. Sci , vol.890 , pp. 107-118
    • Skaper, S.D.1    Floreani, M.2    Ceccon, M.3    Facci, L.4    Giusti, P.5
  • 55
    • 47349084792 scopus 로고    scopus 로고
    • Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice
    • Epub ahead of print
    • Kilic, E., Kilic, U., Bacigaluppi, M., Guo, Z., Abdallah, N.B., Wolfer, D.P., Reiter, R.J., Hermann, D.M., and Bassetti, C.L. (2008) Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice. J. Pineal Res. [Epub ahead of print]
    • (2008) J. Pineal Res
    • Kilic, E.1    Kilic, U.2    Bacigaluppi, M.3    Guo, Z.4    Abdallah, N.B.5    Wolfer, D.P.6    Reiter, R.J.7    Hermann, D.M.8    Bassetti, C.L.9
  • 56
    • 0031835307 scopus 로고    scopus 로고
    • Melatonin prevents the delayed death of hippocampal neurons induced by enhanced excitatory neurotransmission and the nitridergic pathway
    • Skaper, S.D., Ancona, B., Facci, L., Franceschini, D., and Giusti, P. (1998) Melatonin prevents the delayed death of hippocampal neurons induced by enhanced excitatory neurotransmission and the nitridergic pathway. FASEB J. 12, 725-731.
    • (1998) FASEB J , vol.12 , pp. 725-731
    • Skaper, S.D.1    Ancona, B.2    Facci, L.3    Franceschini, D.4    Giusti, P.5
  • 57
    • 12344307153 scopus 로고    scopus 로고
    • Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice
    • Kilic, U., Kilic, E., Reiter, R.J., Bassetti, C.L., and Hermann, D.M. (2005) Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice. J. Pineal Res. 38, 67-71.
    • (2005) J. Pineal Res , vol.38 , pp. 67-71
    • Kilic, U.1    Kilic, E.2    Reiter, R.J.3    Bassetti, C.L.4    Hermann, D.M.5
  • 58
    • 33748978945 scopus 로고    scopus 로고
    • Neurorestorative treatment of stroke: Cell and pharmacological approaches
    • Chen, J. and Chopp, M. (2006) Neurorestorative treatment of stroke: cell and pharmacological approaches. NeuroRx 3, 466-473.
    • (2006) NeuroRx , vol.3 , pp. 466-473
    • Chen, J.1    Chopp, M.2
  • 59
    • 33646337394 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of neural repair after stroke: Making waves
    • Carmichael, S.T. (2006) Cellular and molecular mechanisms of neural repair after stroke: making waves. Ann. Neurol. 59, 735-742.
    • (2006) Ann. Neurol , vol.59 , pp. 735-742
    • Carmichael, S.T.1
  • 60
    • 0035651151 scopus 로고    scopus 로고
    • Reconstructing functional systems after lesions of cerebral cortex
    • Payne, B.R. and Lomber, S.G. (2001) Reconstructing functional systems after lesions of cerebral cortex. Nat. Rev. 2, 911-919.
    • (2001) Nat. Rev , vol.2 , pp. 911-919
    • Payne, B.R.1    Lomber, S.G.2
  • 61
    • 33746308062 scopus 로고    scopus 로고
    • Glial inhibition of CNS axon regeneration
    • Yiu, G. and He, Z. (2006) Glial inhibition of CNS axon regeneration. Nat. Rev. 7, 617-627.
    • (2006) Nat. Rev , vol.7 , pp. 617-627
    • Yiu, G.1    He, Z.2
  • 62
    • 0034638453 scopus 로고    scopus 로고
    • Neutralizing antibodies against neurite growth inhibitor NI-35/250 do not promote regeneration of sensory axons in the adult rat spinal cord
    • Oudega, M., Rosano, C., Sadi, D., Wood, P.M., Schwab, M.E., and Hagg, T. (2000) Neutralizing antibodies against neurite growth inhibitor NI-35/250 do not promote regeneration of sensory axons in the adult rat spinal cord. Neuroscience 100, 873-883.
    • (2000) Neuroscience , vol.100 , pp. 873-883
    • Oudega, M.1    Rosano, C.2    Sadi, D.3    Wood, P.M.4    Schwab, M.E.5    Hagg, T.6
  • 63
    • 0035905799 scopus 로고    scopus 로고
    • Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration
    • Fournier, A.E., GrandPre, T., and Strittmatter, S.M. (2001) Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration. Nature 409, 341-346.
    • (2001) Nature , vol.409 , pp. 341-346
    • Fournier, A.E.1    GrandPre, T.2    Strittmatter, S.M.3
  • 66
    • 0033009765 scopus 로고    scopus 로고
    • Corticostriatal plasticity is restricted by myelin-associated neurite growth inhibitors in the adult rat
    • Kartje, G.L., Schulz, M.K., Lopez-Yunez, A., Schnell, L., and Schwab, M.E. (1999) Corticostriatal plasticity is restricted by myelin-associated neurite growth inhibitors in the adult rat. Ann. Neurol. 45, 778-786.
    • (1999) Ann. Neurol , vol.45 , pp. 778-786
    • Kartje, G.L.1    Schulz, M.K.2    Lopez-Yunez, A.3    Schnell, L.4    Schwab, M.E.5
  • 69
    • 38049069788 scopus 로고    scopus 로고
    • Neural stem/precursor cells for the treatment of ischemic stroke
    • Bacigaluppi, M., Pluchino, S., Martino, G., Kilic, E., and Hermann, D.M. (2007) Neural stem/precursor cells for the treatment of ischemic stroke. J. Neurol. Sci. 265(1-2), 73-77.
    • (2007) J. Neurol. Sci , vol.265 , Issue.1-2 , pp. 73-77
    • Bacigaluppi, M.1    Pluchino, S.2    Martino, G.3    Kilic, E.4    Hermann, D.M.5
  • 70
    • 33846705350 scopus 로고    scopus 로고
    • Cell transplantation therapy for stroke
    • Bliss, T., Guzman, R., Daadi, M., and Steinberg, G.K. (2007) Cell transplantation therapy for stroke. Stroke 38, 817-826.
    • (2007) Stroke , vol.38 , pp. 817-826
    • Bliss, T.1    Guzman, R.2    Daadi, M.3    Steinberg, G.K.4
  • 71
    • 29244463365 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions at the blood-brain barrier
    • Abbott, N.J., Ronnback, L., and Hansson, E. (2006) Astrocyte-endothelial interactions at the blood-brain barrier. Nat. Rev. 7, 41-53.
    • (2006) Nat. Rev , vol.7 , pp. 41-53
    • Abbott, N.J.1    Ronnback, L.2    Hansson, E.3
  • 72
    • 33646591536 scopus 로고    scopus 로고
    • TAT-GDNF in neurodegeneration and ischemic stroke
    • Kilic, E., Kilic, U., and Hermann, D.M. (2005) TAT-GDNF in neurodegeneration and ischemic stroke. CNS Drug Rev. 11, 369-378.
    • (2005) CNS Drug Rev , vol.11 , pp. 369-378
    • Kilic, E.1    Kilic, U.2    Hermann, D.M.3
  • 73
    • 6944255523 scopus 로고    scopus 로고
    • Delivery of therapeutic agents to the central nervous system: The problems and the possibilities
    • Begley, D.J. (2004) Delivery of therapeutic agents to the central nervous system: the problems and the possibilities. Pharmacol. Ther. 104, 29-45.
    • (2004) Pharmacol. Ther , vol.104 , pp. 29-45
    • Begley, D.J.1
  • 74
    • 23044500398 scopus 로고    scopus 로고
    • Drug resistance in brain diseases and the role of drug efflux transporters
    • Loscher, W. and Potschka, H. (2005) Drug resistance in brain diseases and the role of drug efflux transporters. Nat. Rev. 6, 591-602.
    • (2005) Nat. Rev , vol.6 , pp. 591-602
    • Loscher, W.1    Potschka, H.2
  • 75
    • 4744358624 scopus 로고    scopus 로고
    • The ATP switch model for ABC transporters
    • Higgins, C.F. and Linton, K.J. (2004) The ATP switch model for ABC transporters. Nat. Struct. Mol. Biol. 11, 918-926.
    • (2004) Nat. Struct. Mol. Biol , vol.11 , pp. 918-926
    • Higgins, C.F.1    Linton, K.J.2
  • 76
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman, M.M., Fojo, T., and Bates, S.E. (2002) Multidrug resistance in cancer: role of ATP-dependent transporters. Nat. Rev. Cancer 2, 48-58.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 79
    • 32344432793 scopus 로고    scopus 로고
    • Differential, strain-specific cellular and subcellular distribution of multidrug transporters in murine choroid plexus and blood-brain barrier
    • Soontornmalai, A., Vlaming, M.L., and Fritschy, J.M. (2006) Differential, strain-specific cellular and subcellular distribution of multidrug transporters in murine choroid plexus and blood-brain barrier. Neuroscience 138, 159-169.
    • (2006) Neuroscience , vol.138 , pp. 159-169
    • Soontornmalai, A.1    Vlaming, M.L.2    Fritschy, J.M.3
  • 81
    • 33745879440 scopus 로고    scopus 로고
    • Nogo-A-specific antibody treatment enhances sprouting and functional recovery after cervical lesion in adult primates
    • Freund, P., Schmidlin, E., Wannier, T., Bloch, J., Mir, A., Schwab, M.E., and Rouiller, E.M. (2006) Nogo-A-specific antibody treatment enhances sprouting and functional recovery after cervical lesion in adult primates. Nat. Med. 12, 790-792.
    • (2006) Nat. Med , vol.12 , pp. 790-792
    • Freund, P.1    Schmidlin, E.2    Wannier, T.3    Bloch, J.4    Mir, A.5    Schwab, M.E.6    Rouiller, E.M.7
  • 83
    • 35648934511 scopus 로고    scopus 로고
    • Long-term neuroblast migration along blood vessels in an area with transient angiogenesis and increased vascularization after stroke
    • Thored, P., Wood, J., Arvidsson, A., Cammenga, J., Kokaia, Z., and Lindvall, O. (2007) Long-term neuroblast migration along blood vessels in an area with transient angiogenesis and increased vascularization after stroke. Stroke 38, 3032-3039.
    • (2007) Stroke , vol.38 , pp. 3032-3039
    • Thored, P.1    Wood, J.2    Arvidsson, A.3    Cammenga, J.4    Kokaia, Z.5    Lindvall, O.6
  • 84
    • 33947544205 scopus 로고    scopus 로고
    • Neuroblast division during migration toward the ischemic striatum: A study of dynamic migratory and proliferative characteristics of neuroblasts from the subventricular zone
    • Zhang, R.L., LeTourneau, Y., Gregg, S.R., Wang, Y., Toh, Y., Robin, A.M., Zhang, Z.G., and Chopp, M. (2007) Neuroblast division during migration toward the ischemic striatum: a study of dynamic migratory and proliferative characteristics of neuroblasts from the subventricular zone. J. Neurosci. 27, 3157-3162.
    • (2007) J. Neurosci , vol.27 , pp. 3157-3162
    • Zhang, R.L.1    LeTourneau, Y.2    Gregg, S.R.3    Wang, Y.4    Toh, Y.5    Robin, A.M.6    Zhang, Z.G.7    Chopp, M.8
  • 86
    • 43449092523 scopus 로고    scopus 로고
    • Human adult bone marrow-derived somatic cell therapy results in functional recovery and axonal plasticity following stroke in the rat
    • Andrews, E.M., Tsai, S.Y., Johnson, S.C., Farrer, J.R., Wagner, J.P., Kopen, G.C., and Kartje, G.L. (2008) Human adult bone marrow-derived somatic cell therapy results in functional recovery and axonal plasticity following stroke in the rat. Exp. Neurol. 211, 588-592.
    • (2008) Exp. Neurol , vol.211 , pp. 588-592
    • Andrews, E.M.1    Tsai, S.Y.2    Johnson, S.C.3    Farrer, J.R.4    Wagner, J.P.5    Kopen, G.C.6    Kartje, G.L.7
  • 88
    • 0022615539 scopus 로고
    • Recovery of monkey brain after prolonged ischemia. II. Protein synthesis and morphological alterations
    • Bodsch, W., Barbier, A., Oehmichen, M., Grosse Ophoff, B., and Hossmann, K.A. (1986) Recovery of monkey brain after prolonged ischemia. II. Protein synthesis and morphological alterations. J. Cereb. Blood Flow Metab. 6, 22-33.
    • (1986) J. Cereb. Blood Flow Metab , vol.6 , pp. 22-33
    • Bodsch, W.1    Barbier, A.2    Oehmichen, M.3    Grosse Ophoff, B.4    Hossmann, K.A.5
  • 89
    • 0016420719 scopus 로고
    • Experimental model of stroke in the baboon
    • Symon, L. (1975) Experimental model of stroke in the baboon. Adv. Neurol. 10, 199-212.
    • (1975) Adv. Neurol , vol.10 , pp. 199-212
    • Symon, L.1
  • 90
    • 0019507004 scopus 로고
    • Selective lenticulostriate occlusion in the primate. A highly focal cerebral ischemia model
    • Yonas, H., Wolfson, S.K., Jr., Dujovny, M., Boehnke, M., and Cook, E. (1981) Selective lenticulostriate occlusion in the primate. A highly focal cerebral ischemia model. Stroke 12, 567-572.
    • (1981) Stroke , vol.12 , pp. 567-572
    • Yonas, H.1    Wolfson Jr., S.K.2    Dujovny, M.3    Boehnke, M.4    Cook, E.5
  • 91
    • 0014745653 scopus 로고
    • Transorbital approach to the middle cerebral artery of the squirrel monkey: A technique for experimental cerebral infarction applicable to ultrastructural studies
    • Hudgins, W.R. and Garcia, J.H. (1970) Transorbital approach to the middle cerebral artery of the squirrel monkey: a technique for experimental cerebral infarction applicable to ultrastructural studies. Stroke 1, 107-111.
    • (1970) Stroke , vol.1 , pp. 107-111
    • Hudgins, W.R.1    Garcia, J.H.2
  • 92
    • 0026558432 scopus 로고
    • A model of acute focal ischemia in the territory of the anterior cerebral artery in baboons
    • Liu, X.G., Branston, N.M., Kawauchi, M., and Symon, L. (1992) A model of acute focal ischemia in the territory of the anterior cerebral artery in baboons. Stroke 23, 40-44.
    • (1992) Stroke , vol.23 , pp. 40-44
    • Liu, X.G.1    Branston, N.M.2    Kawauchi, M.3    Symon, L.4
  • 93
    • 0028844614 scopus 로고
    • Regional prevalence and distribution of ischemic neurons in dog brains 96 hours after cardiac arrest of 0 to 20 minutes
    • discussion 2133-2124
    • Radovsky, A., Safar, P., Sterz, F., Leonov, Y., Reich, H., and Kuboyama, K. (1995) Regional prevalence and distribution of ischemic neurons in dog brains 96 hours after cardiac arrest of 0 to 20 minutes. Stroke 26, 2127-2133; discussion 2133-2124.
    • (1995) Stroke , vol.26 , pp. 2127-2133
    • Radovsky, A.1    Safar, P.2    Sterz, F.3    Leonov, Y.4    Reich, H.5    Kuboyama, K.6
  • 94
    • 0347174744 scopus 로고    scopus 로고
    • Validation of a four-vessel occlusion model for transient global cerebral ischemia in dogs
    • Pomfy, M. and Franko, J. (1999) Validation of a four-vessel occlusion model for transient global cerebral ischemia in dogs. J. Hirnforsch. 39, 465-471.
    • (1999) J. Hirnforsch , vol.39 , pp. 465-471
    • Pomfy, M.1    Franko, J.2
  • 96
    • 0024384861 scopus 로고    scopus 로고
    • Purdy, P.D., Devous, M.D., Sr., White, C.L., 3rd, Batjer, H.H., Samson, D.S., Brewer, K., and Hodges, K. (1989) Reversible middle cerebral artery embolization in dogs without intracranial surgery. Stroke 20, 1368-1376.
    • Purdy, P.D., Devous, M.D., Sr., White, C.L., 3rd, Batjer, H.H., Samson, D.S., Brewer, K., and Hodges, K. (1989) Reversible middle cerebral artery embolization in dogs without intracranial surgery. Stroke 20, 1368-1376.
  • 97
    • 0023914223 scopus 로고
    • A new model of brainstem ischemia in dogs
    • Kuwabara, S., Uno, J., and Ishikawa, S. (1988) A new model of brainstem ischemia in dogs. Stroke 19, 365-371.
    • (1988) Stroke , vol.19 , pp. 365-371
    • Kuwabara, S.1    Uno, J.2    Ishikawa, S.3
  • 98
    • 0023239015 scopus 로고
    • Intracellular acidosis during and after cerebral ischemia: In vivo nuclear magnetic resonance study of hyperglycemia in cats
    • Chopp, M., Frinak, S., Walton, D.R., Smith, M.B., and Welch, K.M. (1987) Intracellular acidosis during and after cerebral ischemia: in vivo nuclear magnetic resonance study of hyperglycemia in cats. Stroke 18, 919-923.
    • (1987) Stroke , vol.18 , pp. 919-923
    • Chopp, M.1    Frinak, S.2    Walton, D.R.3    Smith, M.B.4    Welch, K.M.5
  • 99
    • 0014912745 scopus 로고
    • The effect of ischemia on sensorimotor cortex of cat. Electrophysiological, biochemical and electronmicroscopial observations
    • Hossmann, K.A. and Sato, K. (1970) The effect of ischemia on sensorimotor cortex of cat. Electrophysiological, biochemical and electronmicroscopial observations. Z. Neurol. 198, 33-45.
    • (1970) Z. Neurol , vol.198 , pp. 33-45
    • Hossmann, K.A.1    Sato, K.2
  • 100
    • 0015790186 scopus 로고
    • Transorbital approach for occluding the middle cerebral artery without craniectomy
    • O'Brien, M.D. and Waltz, A.G. (1973) Transorbital approach for occluding the middle cerebral artery without craniectomy. Stroke 4, 201-206.
    • (1973) Stroke , vol.4 , pp. 201-206
    • O'Brien, M.D.1    Waltz, A.G.2
  • 101
    • 0021970033 scopus 로고
    • Effects of indomethacin on rCBF during and after focal cerebral ischemia in the cat
    • Shigeno, S., Fritschka, E., Shigeno, T., and Brock, M. (1985) Effects of indomethacin on rCBF during and after focal cerebral ischemia in the cat. Stroke 16, 235-240.
    • (1985) Stroke , vol.16 , pp. 235-240
    • Shigeno, S.1    Fritschka, E.2    Shigeno, T.3    Brock, M.4
  • 102
    • 0026354905 scopus 로고
    • Epinephrine dosage effects on cerebral and myocardial blood flow in an infant swine model of cardiopulmonary resuscitation
    • Berkowitz, I.D., Gervais, H., Schleien, C.L., Koehler, R.C., Dean, J.M., and Traystman, R.J. (1991) Epinephrine dosage effects on cerebral and myocardial blood flow in an infant swine model of cardiopulmonary resuscitation. Anesthesiology 75, 1041-1050.
    • (1991) Anesthesiology , vol.75 , pp. 1041-1050
    • Berkowitz, I.D.1    Gervais, H.2    Schleien, C.L.3    Koehler, R.C.4    Dean, J.M.5    Traystman, R.J.6
  • 103
    • 0033868340 scopus 로고    scopus 로고
    • Cerebral blood flow and blood volume measured by magnetic resonance imaging bolus tracking after acute stroke in pigs: Comparison with [(15)O]H(2)O positron emission tomography
    • Sakoh, M., Rohl, L., Gyldensted, C., Gjedde, A., and Ostergaard, L. (2000) Cerebral blood flow and blood volume measured by magnetic resonance imaging bolus tracking after acute stroke in pigs: comparison with [(15)O]H(2)O positron emission tomography. Stroke 31, 1958-1964.
    • (2000) Stroke , vol.31 , pp. 1958-1964
    • Sakoh, M.1    Rohl, L.2    Gyldensted, C.3    Gjedde, A.4    Ostergaard, L.5
  • 104
    • 0020051129 scopus 로고
    • Delayed neuronal death in the gerbil hippocampus following ischemia
    • Kirino, T. (1982) Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res. 239, 57-69.
    • (1982) Brain Res , vol.239 , pp. 57-69
    • Kirino, T.1
  • 105
    • 0013970039 scopus 로고
    • Effects of ischemia and other procedures on the brain and retina of the gerbil (Meriones unguiculatus)
    • Levine, S. and Payan, H. (1966) Effects of ischemia and other procedures on the brain and retina of the gerbil (Meriones unguiculatus). Exp. Neurol. 16, 255-262.
    • (1966) Exp. Neurol , vol.16 , pp. 255-262
    • Levine, S.1    Payan, H.2
  • 106
    • 0036712353 scopus 로고    scopus 로고
    • Microplasmin: A novel thrombolytic that improves behavioral outcome after embolic strokes in rabbits
    • Lapchak, P.A., Araujo, D.M., Pakola, S., Song, D., Wei, J., and Zivin, J.A. (2002) Microplasmin: a novel thrombolytic that improves behavioral outcome after embolic strokes in rabbits. Stroke 33, 2279-2284.
    • (2002) Stroke , vol.33 , pp. 2279-2284
    • Lapchak, P.A.1    Araujo, D.M.2    Pakola, S.3    Song, D.4    Wei, J.5    Zivin, J.A.6
  • 107
    • 0018044923 scopus 로고
    • Effect of glucose and insulin pretreatment on cerebral metabolic recovery after ischemia
    • Gjedde, A. and Siemkowicz, E. (1978) Effect of glucose and insulin pretreatment on cerebral metabolic recovery after ischemia. Trans. Am. Neurol. Assoc. 103, 45-47.
    • (1978) Trans. Am. Neurol. Assoc , vol.103 , pp. 45-47
    • Gjedde, A.1    Siemkowicz, E.2
  • 108
    • 37849016901 scopus 로고    scopus 로고
    • A new model of cardiac arrest in rats?
    • Bottiger, B.W., Popp, E., and Teschendorf, P. (2007) A new model of cardiac arrest in rats? Resuscitation 76(2), 317-318.
    • (2007) Resuscitation , vol.76 , Issue.2 , pp. 317-318
    • Bottiger, B.W.1    Popp, E.2    Teschendorf, P.3
  • 110
    • 0018347695 scopus 로고
    • A new model of bilateral hemispheric ischemia in the unanesthetized rat
    • Pulsinelli, W.A. and Brierley, J.B. (1979) A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 10, 267-272.
    • (1979) Stroke , vol.10 , pp. 267-272
    • Pulsinelli, W.A.1    Brierley, J.B.2
  • 111
    • 0015465251 scopus 로고
    • The effect of bilateral carotid artery ligation upon acid-base parameters and substrate levels in the rat brain
    • Eklof, B. and Siesjo, B.K. (1972) The effect of bilateral carotid artery ligation upon acid-base parameters and substrate levels in the rat brain. Acta Physiol. Scand. 86, 528-538.
    • (1972) Acta Physiol. Scand , vol.86 , pp. 528-538
    • Eklof, B.1    Siesjo, B.K.2
  • 112
    • 0026598564 scopus 로고
    • Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats
    • Memezawa, H., Smith, M.L., and Siesjo, B.K. (1992) Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats. Stroke 23, 552-559.
    • (1992) Stroke , vol.23 , pp. 552-559
    • Memezawa, H.1    Smith, M.L.2    Siesjo, B.K.3
  • 113
    • 0031665617 scopus 로고    scopus 로고
    • A critical reevaluation of the intraluminal thread model of focal cerebral ischemia: Evidence of inadvertent premature reperfusion and subarachnoid hemorrhage in rats by laser-Doppler flowmetry
    • Schmid-Elsaesser, R., Zausinger, S., Hungerhuber, E., Baethmann, A., and Reulen, H.J. (1998) A critical reevaluation of the intraluminal thread model of focal cerebral ischemia: evidence of inadvertent premature reperfusion and subarachnoid hemorrhage in rats by laser-Doppler flowmetry. Stroke 29, 2162-2170.
    • (1998) Stroke , vol.29 , pp. 2162-2170
    • Schmid-Elsaesser, R.1    Zausinger, S.2    Hungerhuber, E.3    Baethmann, A.4    Reulen, H.J.5
  • 114
    • 0019868418 scopus 로고
    • Focal cerebral ischaemia in the rat: 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion
    • Tamura, A., Graham, D.I., McCulloch, J., and Teasdale, G.M. (1981) Focal cerebral ischaemia in the rat: 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J. Cereb. Blood Flow Metab. 1, 53-60.
    • (1981) J. Cereb. Blood Flow Metab , vol.1 , pp. 53-60
    • Tamura, A.1    Graham, D.I.2    McCulloch, J.3    Teasdale, G.M.4
  • 115
    • 0023786051 scopus 로고
    • Focal brain ischemia in the rat: Methods for reproducible neocortical infarction using tandem occlusion of the distal middle cerebral and ipsilateral common carotid arteries
    • Brint, S., Jacewicz, M., Kiessling, M., Tanabe, J., and Pulsinelli, W. (1988) Focal brain ischemia in the rat: methods for reproducible neocortical infarction using tandem occlusion of the distal middle cerebral and ipsilateral common carotid arteries. J. Cereb. Blood Flow Metab. 8, 474-485.
    • (1988) J. Cereb. Blood Flow Metab , vol.8 , pp. 474-485
    • Brint, S.1    Jacewicz, M.2    Kiessling, M.3    Tanabe, J.4    Pulsinelli, W.5
  • 116
    • 0022545394 scopus 로고
    • A model of focal ischemic stroke in the rat: Reproducible extensive cortical infarction
    • Chen, S.T., Hsu, C.Y., Hogan, E.L., Maricq, H., and Balentine, J.D. (1986) A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction. Stroke 17, 738-743.
    • (1986) Stroke , vol.17 , pp. 738-743
    • Chen, S.T.1    Hsu, C.Y.2    Hogan, E.L.3    Maricq, H.4    Balentine, J.D.5
  • 117
    • 0023156087 scopus 로고
    • Photochemically induced cerebral infarction. II. Edema and blood-brain barrier disruption
    • Dietrich, W.D., Busto, R., Watson, B.D., Scheinberg, P., and Ginsberg, M.D. (1987) Photochemically induced cerebral infarction. II. Edema and blood-brain barrier disruption. Acta Neuropathol. 72, 326-334.
    • (1987) Acta Neuropathol , vol.72 , pp. 326-334
    • Dietrich, W.D.1    Busto, R.2    Watson, B.D.3    Scheinberg, P.4    Ginsberg, M.D.5
  • 118
    • 0035045299 scopus 로고    scopus 로고
    • Patency of cerebral microvessels after focal embolic stroke in the rat
    • Wang, C.X., Todd, K.G., Yang, Y., Gordon, T., and Shuaib, A. (2001) Patency of cerebral microvessels after focal embolic stroke in the rat. J. Cereb. Blood Flow Metab. 21, 413-421.
    • (2001) J. Cereb. Blood Flow Metab , vol.21 , pp. 413-421
    • Wang, C.X.1    Todd, K.G.2    Yang, Y.3    Gordon, T.4    Shuaib, A.5
  • 120
    • 0034237128 scopus 로고    scopus 로고
    • Neuroprotective effects of estrogens: Potential mechanisms of action
    • Green, P.S. and Simpkins, J.W. (2000) Neuroprotective effects of estrogens: potential mechanisms of action. Int. J. Dev. Neurosci. 18, 347-358.
    • (2000) Int. J. Dev. Neurosci , vol.18 , pp. 347-358
    • Green, P.S.1    Simpkins, J.W.2
  • 122
    • 0033497678 scopus 로고    scopus 로고
    • Neuroprotection by estrogens in a mouse model of focal cerebral ischemia and in cultured neurons: Evidence for a receptor-independent antioxidative mechanism
    • Culmsee, C., Vedder, H., Ravati, A., Junker, V., Otto, D., Ahlemeyer, B., Krieg, J.C., and Krieglstein, J. (1999) Neuroprotection by estrogens in a mouse model of focal cerebral ischemia and in cultured neurons: evidence for a receptor-independent antioxidative mechanism. J. Cereb. Blood Flow Metab. 19, 1263-1269.
    • (1999) J. Cereb. Blood Flow Metab , vol.19 , pp. 1263-1269
    • Culmsee, C.1    Vedder, H.2    Ravati, A.3    Junker, V.4    Otto, D.5    Ahlemeyer, B.6    Krieg, J.C.7    Krieglstein, J.8
  • 123
    • 0036289498 scopus 로고    scopus 로고
    • Minocycline markedly protects the neonatal brain against hypoxic-ischemic injury
    • Arvin, K.L., Han, B.H., Du, Y., Lin, S.Z., Paul, S.M., and Holtzman, D.M. (2002) Minocycline markedly protects the neonatal brain against hypoxic-ischemic injury. Ann. Neurol. 52, 54-61.
    • (2002) Ann. Neurol , vol.52 , pp. 54-61
    • Arvin, K.L.1    Han, B.H.2    Du, Y.3    Lin, S.Z.4    Paul, S.M.5    Holtzman, D.M.6
  • 124
    • 1542376941 scopus 로고    scopus 로고
    • Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury
    • Stirling, D.P., Khodarahmi, K., Liu, J., McPhail, L.T., McBride, C.B., Steeves, J.D., Ramer, M.S., and Tetzlaff, W. (2004) Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury. J. Neurosci. 24, 2182-2190.
    • (2004) J. Neurosci , vol.24 , pp. 2182-2190
    • Stirling, D.P.1    Khodarahmi, K.2    Liu, J.3    McPhail, L.T.4    McBride, C.B.5    Steeves, J.D.6    Ramer, M.S.7    Tetzlaff, W.8
  • 128
    • 0035876916 scopus 로고    scopus 로고
    • Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia
    • Tikka, T.M. and Koistinaho, J.E. (2001) Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia. J. Immunol. 166, 7527-7533.
    • (2001) J. Immunol , vol.166 , pp. 7527-7533
    • Tikka, T.M.1    Koistinaho, J.E.2
  • 130
    • 0035833541 scopus 로고    scopus 로고
    • Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades
    • Digicaylioglu, M. and Lipton, S.A. (2001) Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature 412, 641-647.
    • (2001) Nature , vol.412 , pp. 641-647
    • Digicaylioglu, M.1    Lipton, S.A.2
  • 133
    • 13244252517 scopus 로고    scopus 로고
    • Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2
    • Kilic, U., Kilic, E., Soliz, J., Bassetti, C.I., Gassmann, M., and Hermann, D.M. (2005) Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2. FASEB J. 19, 249-251.
    • (2005) FASEB J , vol.19 , pp. 249-251
    • Kilic, U.1    Kilic, E.2    Soliz, J.3    Bassetti, C.I.4    Gassmann, M.5    Hermann, D.M.6
  • 134
    • 28744455284 scopus 로고    scopus 로고
    • Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways
    • Kilic, E., Kilic, U., Soliz, J., Bassetti, C.L., Gassmann, M., and Hermann, D.M. (2005) Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways. FASEB J. 19, 2026-2028.
    • (2005) FASEB J , vol.19 , pp. 2026-2028
    • Kilic, E.1    Kilic, U.2    Soliz, J.3    Bassetti, C.L.4    Gassmann, M.5    Hermann, D.M.6
  • 135
    • 0041743159 scopus 로고    scopus 로고
    • VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia
    • Sun, Y., Jin, K., Xie, L., Childs, J., Mao, X.O., Logvinova, A., and Greenberg, D.A. (2003) VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia. J. Clin. Invest. 111, 1843-1851.
    • (2003) J. Clin. Invest , vol.111 , pp. 1843-1851
    • Sun, Y.1    Jin, K.2    Xie, L.3    Childs, J.4    Mao, X.O.5    Logvinova, A.6    Greenberg, D.A.7
  • 136
    • 11244276997 scopus 로고    scopus 로고
    • VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena
    • Wang, Y., Kilic, E., Kilic, U., Weber, B., Bassetti, C.L., Marti, H.H., and Hermann, D.M. (2005) VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena. Brain 128, 52-63.
    • (2005) Brain , vol.128 , pp. 52-63
    • Wang, Y.1    Kilic, E.2    Kilic, U.3    Weber, B.4    Bassetti, C.L.5    Marti, H.H.6    Hermann, D.M.7
  • 138
    • 34547461194 scopus 로고    scopus 로고
    • Decreased focal inflammatory response by G-CSF may improve stroke outcome after transient middle cerebral artery occlusion in rats
    • Sehara, Y., Hayashi, T., Deguchi, K., Zhang, H., Tsuchiya, A., Yamashita, T., Lukic, V., Nagai, M., Kamiya, T., and Abe, K. (2007) Decreased focal inflammatory response by G-CSF may improve stroke outcome after transient middle cerebral artery occlusion in rats. J. Neurosci. Res. 85, 2167-2174.
    • (2007) J. Neurosci. Res , vol.85 , pp. 2167-2174
    • Sehara, Y.1    Hayashi, T.2    Deguchi, K.3    Zhang, H.4    Tsuchiya, A.5    Yamashita, T.6    Lukic, V.7    Nagai, M.8    Kamiya, T.9    Abe, K.10
  • 140
    • 34347225908 scopus 로고    scopus 로고
    • Neuroprotection of G-CSF in cerebral ischemia
    • Lu, C.Z. and Xiao, B.G. (2007) Neuroprotection of G-CSF in cerebral ischemia. Front. Biosci. 12, 2869-2875.
    • (2007) Front. Biosci , vol.12 , pp. 2869-2875
    • Lu, C.Z.1    Xiao, B.G.2
  • 141
    • 33847654606 scopus 로고    scopus 로고
    • Intravenous administration of melatonin reduces the intracerebral cellular inflammatory response following transient focal cerebral ischemia in rats
    • Lee, M.Y., Kuan, Y.H., Chen, H.Y., Chen, T.Y., Chen, S.T., Huang, C.C., Yang, I.P., Hsu, Y.S., Wu, T.S., and Lee, E.J. (2007) Intravenous administration of melatonin reduces the intracerebral cellular inflammatory response following transient focal cerebral ischemia in rats. J. Pineal Res. 42, 297-309.
    • (2007) J. Pineal Res , vol.42 , pp. 297-309
    • Lee, M.Y.1    Kuan, Y.H.2    Chen, H.Y.3    Chen, T.Y.4    Chen, S.T.5    Huang, C.C.6    Yang, I.P.7    Hsu, Y.S.8    Wu, T.S.9    Lee, E.J.10
  • 143
    • 0028362424 scopus 로고
    • Mild intraischemic hypothermia reduces postischemic hyperperfusion, delayed postischemic hypoperfusion, blood-brain barrier disruption, brain edema, and neuronal damage volume after temporary focal cerebral ischemia in rats
    • Karibe, H., Zarow, G.J., Graham, S.H., and Weinstein, P.R. (1994) Mild intraischemic hypothermia reduces postischemic hyperperfusion, delayed postischemic hypoperfusion, blood-brain barrier disruption, brain edema, and neuronal damage volume after temporary focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 14, 620-627.
    • (1994) J. Cereb. Blood Flow Metab , vol.14 , pp. 620-627
    • Karibe, H.1    Zarow, G.J.2    Graham, S.H.3    Weinstein, P.R.4
  • 144
    • 0033821072 scopus 로고    scopus 로고
    • Feasibility and safety of inducing modest hypothermia in awake patients with acute stroke through surface cooling: A case-control study: the Copenhagen Stroke Study
    • Kammersgaard, L.P., Rasmussen, B.H., Jorgensen, H.S., Reith, J., Weber, U., and Olsen, T.S. (2000) Feasibility and safety of inducing modest hypothermia in awake patients with acute stroke through surface cooling: a case-control study: the Copenhagen Stroke Study. Stroke 31, 2251-2256.
    • (2000) Stroke , vol.31 , pp. 2251-2256
    • Kammersgaard, L.P.1    Rasmussen, B.H.2    Jorgensen, H.S.3    Reith, J.4    Weber, U.5    Olsen, T.S.6
  • 145
    • 41349092724 scopus 로고    scopus 로고
    • Neuroprotection by oxygen in acute transient focal cerebral ischemia is dose dependent and shows superiority of hyperbaric oxygenation
    • Eschenfelder, C.C., Krug, R., Yusofi, A.F., Meyne, J.K., Herdegen, T., Koch, A., Zhao, Y., Carl, U.M., and Deuschl, G. (2008) Neuroprotection by oxygen in acute transient focal cerebral ischemia is dose dependent and shows superiority of hyperbaric oxygenation. Cerebrovasc. Dis. 25, 193-201.
    • (2008) Cerebrovasc. Dis , vol.25 , pp. 193-201
    • Eschenfelder, C.C.1    Krug, R.2    Yusofi, A.F.3    Meyne, J.K.4    Herdegen, T.5    Koch, A.6    Zhao, Y.7    Carl, U.M.8    Deuschl, G.9
  • 146
    • 16344381726 scopus 로고    scopus 로고
    • Normobaric hyperoxia extends the reperfusion window in focal cerebral ischemia
    • Kim, H.Y., Singhal, A.B., and Lo, E.H. (2005) Normobaric hyperoxia extends the reperfusion window in focal cerebral ischemia. Ann. Neurol. 57, 571-575.
    • (2005) Ann. Neurol , vol.57 , pp. 571-575
    • Kim, H.Y.1    Singhal, A.B.2    Lo, E.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.