Functional genomics reveals increases in cholesterol biosynthetic genes and highly unsaturated fatty acid biosynthesis after dietary substitution of fish oil with vegetable oils in Atlantic salmon (Salmo salar)

BMC Genomics

Volumn 9, Issue , 2008, Pages

  Leaver, Michael J ^a   Villeneuve, Laure A N ^a   Obach, Alex ^b   Jensen, Linda ^b   Bron, James E ^a   Tocher, Douglas R ^a   Taggart, John B ^a  

^a UNIVERSITY OF STIRLING   (United Kingdom)

^b SKRETTING AQUACULTURE RESEARCH CENTRE   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

FISH OIL; LINSEED OIL; LIPID; PROTEIN; RAPESEED OIL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SOYBEAN OIL; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; UNSATURATED FATTY ACID; VEGETABLE OIL; CHOLESTEROL; COMPLEMENTARY DNA; MALATE DEHYDROGENASE;

ANIMAL FOOD; AQUACULTURE; ARTICLE; ATLANTIC SALMON; CHEMICAL ANALYSIS; CHOLESTEROL INTAKE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DNA MICROARRAY; ENZYME SYNTHESIS; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; FOOD INTAKE; FUNCTIONAL GENOMICS; GENE EXPRESSION; GROWTH RATE; LIPID ANALYSIS; LIPID COMPOSITION; LIPID STORAGE; LIPID TRANSPORT; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN CONTENT; PROTEIN PROCESSING; RNA PROCESSING; TRANSCRIPTION REGULATION; UNINDEXED SEQUENCE; ANIMAL; ATLANTIC OCEAN; BIOSYNTHESIS; BODY WEIGHT; ENZYMOLOGY; FAT INTAKE; GENE EXPRESSION PROFILING; GENETICS; GENOMICS; LIPID METABOLISM; LIVER; METABOLISM; METHODOLOGY;

ANIMALIA; BRASSICA NAPUS; GLYCINE MAX; SALMO SALAR;

ANIMAL FEED; ANIMALS; ATLANTIC OCEAN; BODY WEIGHT; CHOLESTEROL; DIETARY FATS; DNA, COMPLEMENTARY; FATTY ACIDS, UNSATURATED; FISH OILS; GENE EXPRESSION PROFILING; GENOMICS; LIPID METABOLISM; LIVER; MALATE DEHYDROGENASE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLANT OILS; SALMO SALAR;

EID: 47249104362     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-9-299     Document Type: Article

References (44)

1. Sargent JR Tacon AGJ Development of farmed fish: A nutritionally necessary alternative to meat Proceedings of the Nutrition Society 1999, 58:377-383. 10466180
2. Torstensen BE Bell JG Rosenlund G Henderson RJ Graff IE Tocher DR Lie O Sargent JR Tailoring of Atlantic salmon (Salmo salar L.) flesh lipid composition and sensory quality by replacing fish oil with a vegetable oil blend Journal of Agricultural and Food Chemistry 2005, 53:10166-10178. 10.1021/jf051308i
3. Bell JG McVicar AH Park MT Sargent JR High Dietary Linoleic-Acid Affects the Fatty-Acid Compositions of Individual Phospholipids from Tissues of Atlantic Salmon (Salmo Salar) - Association with Stress Susceptibility and Cardiac Lesion Journal of Nutrition 1991, 121:1163-1172. 1861166
4. Bell JG Tocher DR Farndale BM McVicar AH Sargent JR Effects of essential fatty acid-deficient diets on growth, mortality, tissue histopathology and fatty acid compositions in juvenile turbot (Scophthalmus maximus) Fish Physiology and Biochemistry 1999, 20:263-277. 10.1023/ A:1007743532618
5. Mourente G Good JE Bell JG Partial substitution of fish oil with rapeseed, linseed and olive oils in diets for European sea bass (Dicentrarchus labrax L.): Effects on flesh fatty acid composition, plasma prostaglandins E-2 and F-2 alpha, immune function and effectiveness of a fish oil finishing diet Aquaculture Nutrition 2005, 11:25-40. 10.1111/j.1365-2095.2004.00320.x
6. Olsen RE Myklebust R Ringo E Mayhew TM The influences of dietary linseed oil and saturated fatty acids on caecal enterocytes in Arctic char (Salvelinus alpinus L.): A quantitative ultrastructural study Fish Physiology and Biochemistry 2000, 22:207-216. 10.1023/A:1007879127182
7. Olsen RE Dragnes BT Myklebust R Ringo E Effect of soybean oil and soybean lecithin on intestinal lipid composition and lipid droplet accumulation of rainbow trout, Oncorhynchus mykiss Walbaum Fish Physiology and Biochemistry 2003, 29:181-192. 10.1023/ B:FISH.0000045708.67760.43
8. Caballero MJ Obach A Rosenlund G Montero D Gisvold M Izquierdo MS Impact of different dietary lipid sources on growth, lipid digestibility, tissue fatty acid composition and histology of rainbow trout, Oncorhynchus mykiss Aquaculture 2002, 214:253-271. 10.1016/ S0044-8486(01)00852-3
9. Caballero MJ Izquierdo MS Kjorsvik E Montero D Socorro J Fernandez AJ Rosenlund G Morphological aspects of intestinal cells from gilthead seabream (Sparus aurata) fed diets containing different lipid sources Aquaculture 2003, 225:325-340. 10.1016/S0044-8486(03)00299-0
10. Bell JG Tocher DR Henderson RJ Dick JR Crampton VO Altered fatty acid compositions in Atlantic salmon (Salmo salar) fed diets containing linseed and rapeseed oils can be partially restored by a subsequent fish oil finishing diet Journal of Nutrition 2003, 133:2793-2801. 12949367
11. von Schalburg KR Rise ML Cooper GA Brown GD Gibbs AR Nelson CC Davidson WS Koop BF Fish and chips: Various methodologies demonstrate utility of a 16,006-gene salmonid microarray BMC Genomics 2005, 6:126. 16164747 1239916 10.1186/1471-2164-6-126
12. Taggart JB Bron JE Martin SAM Seear P Hoyheim B Talbot R Villeneuve L Sweeney GE Houlihan DF Secombes CJ Tocher DR Teale AJ A description of the origin, designs and performance of the TRAITS/SGP Atlantic salmon (Salmo salar) cDNA microarray. Journal of Fish Biology 2008.
13. Rosenlund G Obach A Sandberg MG Standal H Tveit K Effect of alternative lipid sources on long-term growth performance and quality of Atlantic salmon (Salmo salar L.) Aquaculture Research 2001, 32:323-328. 10.1046/ j.1355-557x.2001.00025.x
14. Torstensen BE Lie O Froyland L Lipid metabolism and tissue composition in Atlantic salmon (Salmo salar L.) - Effects of capelin oil, palm oil, and oleic acid-enriched sunflower oil as dietary lipid sources Lipids 2000, 35:653-664. 10.1007/s11745-000-0570-6 10901428
15. Zheng XZ Torstensen BE Tocher DR Dick JR Henderson RJ Bell JG Environmental and dietary influences on highly unsaturated fatty acid biosynthesis and expression of fatty acyl desaturase and elongase genes in liver of Atlantic salmon (Salmo salar) Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids 2005, 1734:13-24. 10.1016/ j.bbalip.2005.01.006
16. Tocher DR Bell JG McGhee F Dick JR Fonseca-Madrigal J Effects of dietary lipid level and vegetable oil on fatty acid metabolism in Atlantic salmon (Salmo salar L.) over the whole production cycle Fish Physiology and Biochemistry 2003, 29:193-209. 10.1023/B:FISH.0000045722.44186.ee
17. Horton JD Shah NA Warrington JA Anderson NN Park SW Brown MS Goldstein JL Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes Proceedings of the National Academy of Sciences of the United States of America 2003, 100:12027-12032. 218707 14512514 10.1073/pnas.1534923100
18. Tocher DR Bendiksen EA Campbell PJ Bell JG The role of phospholipids in nutrition and metabolism of teleost fish Aquaculture 2008.
19. Phillips KM Ruggio DM Toivo JI Swank MA Simpkins AH Free and esterified sterol composition of edible oils and fats Journal of Food Composition and Analysis 2002, 15:123-142. 10.1006/jfca.2001.1044
20. Ostlund RE Phytosterols and cholesterol metabolism Current Opinion in Lipidology 2004, 15:37-41. 10.1097/00041433-200402000-00008 15166807
21. Jordal AEO Lie O Torstensen BE Complete replacement of dietary fish oil with a vegetable oil blend affect liver lipid and plasma lipoprotein levels in Atlantic salmon (Salmo salar L.) Aquaculture Nutrition 2007, 13:114-130. 10.1111/j.1365-2095.2007.00455.x
22. Kersten S Regulation of lipid metabolism via angiopoietin-like proteins Biochemical Society Transactions 2005, 33:1059-1062. 10.1042/BST20051059 16246045
23. Deng GJ Laursen RA Isolation and characterization of an antifreeze protein from the longhorn sculpin, Myoxocephalus octodecimspinosis Biochimica et Biophysica Acta-Protein Structure and Molecular Enzymology 1998, 1388:305-314. 10.1016/S0167-4838(98)00180-0
24. Bengtsson E To F Hakansson K Grubb A Branen L Nilsson J Jovinge S Lack of the cysteine protease inhibitor cystatin C promotes atherosclerosis in apolipoprotein E-deficient mice Arteriosclerosis Thrombosis and Vascular Biology 2005, 25:2151-2156. 10.1161/01.ATV.0000179600.34086.7d
25. Voshol PJ Minich DM Havinga R Elferink RPJO Verkade HJJ Groen AK Kuipers F Postprandial chylomicron formation and fat absorption in multidrug resistance gene 2 P-glycoprotein-deficient mice Gastroenterology 2000, 118:173-182. 10.1016/S0016-5085(00)70426-4 10611166
26. Pollak N Dolle C Ziegler M The power to reduce: Pyridine nucleotides - small molecules with a multitude of functions Biochemical Journal 2007, 402:205-218. 1798440 17295611 10.1042/BJ20061638
27. Stubhaug I Lie O Torstensen BE Fatty acid productive value and beta-oxidation capacity in Atlantic salmon (Salmo salar L.) fed on different lipid sources along the whole growth period Aquaculture Nutrition 2007, 13:145-155. 10.1111/j.1365-2095.2007.00462.x
28. Stubhaug I Tocher DR Bell JG Dick JR Torstensen BE Fatty acid metabolism in Atlantic salmon (Salmo salar L.) hepatocytes and influence of dietary vegetable oil Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids 2005, 1734:277-288. 10.1016/j.bbalip.2005.04.003
29. Froyland L Lie O Berge RK Mitochondrial and peroxisomal beta-oxidation capacities in various tissues from Atlantic salmon Salmo salar Aquaculture Nutrition 2000, 6:85-89. 10.1046/j.1365-2095.2000.00130.x
30. Morais S Knoll-Gellida A Andre M Barthe C Babin PJ Conserved expression of alternative splicing variants of peroxisomal acyl- CoA oxidase 1 in vertebrates and developmental and nutritional regulation in fish Physiological Genomics 2007, 28:239-252. 10.1152/ physiolgenomics.00136.2006 17090698
31. Diez A Menoyo D Perez-Benavente S Calduch-Giner JA de Celis SVR Obach A Favre-Krey L Boukouvala E Leaver MJ Tocher DR Perez-Sanchez J Krey G Bautista JM Conjugated linoleic acid affects lipid composition, metabolism, and gene expression in Gilthead sea bream (Sparus aurata L) Journal of Nutrition 2007, 137:1363-1369. 17513392
32. Desvergne BA Michalik L Wahli W Transcriptional regulation of metabolism Physiological Reviews 2006, 86:465-514. 10.1152/physrev.00025.2005 16601267
33. Leaver MJ Boukouvala E Antonopoulou E Diez A Favre-Krey L Ezaz MT Bautista JM Tocher DR Krey G Three peroxisome proliferator-activated receptor isotypes from each of two species of marine fish Endocrinology 2005, 146:3150-3162. 10.1210/en.2004-1638 15790725
34. Leaver MJ Ezaz MT Fontagne S Tocher DR Boukouvala E Krey G Multiple peroxisome proliferator-activated receptor beta subtypes from Atlantic salmon (Salmo salar) Journal of Molecular Endocrinology 2007, 38:391-400. 10.1677/JME-06-0043 17339402
35. Jordal AE Torstensen BE Tsoi S Tocher DR Lall SP Douglas SE Dietary rapeseed oil affects the expression of genes involved in hepatic lipid metabolism in Atlantic salmon (Salmo salar L.) J Nutr 2005, 135:2355-2361. 16177195
36. Ruyter B Moya-Falcon C Rosenlund G Vegusdal A Fat content and morphology of liver and intestine of Atlantic salmon (Salmo salar): Effects of temperature and dietary soybean oil Aquaculture 2006, 252:441-452. 10.1016/j.aquaculture.2005.07.014
37. Motomura W Inoue M Ohtake T Takahashi N Nagamine M Tanno S Kohgo Y Okumura T Up-regulation of ADRP in fatty liver in human and liver steatosis in mice fed with high fat diet Biochemical and Biophysical Research Communications 2006, 340:1111-1118. 10.1016/j.bbrc.2005.12.121
38. Leaver MJ Tocher DR Obach A Jensen L Henderson RJ Porter AR Krey G Effect of dietary conjugated linoleic acid (CLA) on lipid composition, metabolism and gene expression in Atlantic salmon (Salmo salar) tissues Comparative Biochemistry and Physiology A-Molecular & Integrative Physiology 2006, 145:258-267. 10.1016/j.cbpa.2006.06.034
39. Brazma A Hingamp P Quackenbush J Sherlock G Spellman P Stoeckert C Aach J Ansorge W Ball CA Causton HC Gaasterland T Glenisson P Holstege FCP Kim IF Markowitz V Matese JC Parkinson H Robinson A Sarkans U Schulze-Kremer S Stewart J Taylor R Vilo J Vingron M Minimum information about a microarray experiment (MIAME) - toward standards for microarray data Nature Genetics 2001, 29:365-371. 10.1038/ng1201-365 11726920
40. ArrayExpress 2008. http://www.ebi.ac.uk/arrayexpress
41. Primer3 2008. http://frodo.wi.mit.edu/cgi-bin/primer3/primer3_www.cgi
42. wwwGene-Quantificationinfo 2008. http://www.gene-quantification.info/
43. Pfaffl MW Horgan GW Dempfle L Relative expression software tool (REST (c)) for group-wise comparison and statistical analysis of relative expression results in real-time PCR Nucleic Acids Research 2002:30. 113859 11972351
44. Martin SAM Taggart JB Seear P Bron JE Talbot R Teale AJ Sweeney GE Hoyheim B Houlihan DF Tocher DR Zou J Secombes CJ Interferon type I and type II responses in an Atlantic salmon (Salmo salar) SHK-1 cell line by the salmon TRAITS/SGP microarray Physiological Genomics 2007, 32:33-44. 10.1152/physiolgenomics.00064.2007 17804604