Formation of tissue factor-factor VIIa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells

Thrombosis and Haemostasis

Volumn 100, Issue 1, 2008, Pages 127-133

  Jiang, Xiaofeng ^a   Zhu, Shimei ^a   Panetti, Tracee S ^a   Bromberg, Michael E ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Breast cancer; Factor VIIa; Factor Xa; Mammalian target of rapamycin; Tissue factor

Indexed keywords

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 7A; MAMMALIAN TARGET OF RAPAMYCIN; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; RAPAMYCIN; S6 KINASE;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL MIGRATION; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CHROMONES; FACTOR VIIA; FACTOR XA; FEMALE; HUMANS; MORPHOLINES; NEOPLASM INVASIVENESS; PEPTIDES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, PAR-1; RECEPTOR, PAR-2; RECOMBINANT PROTEINS; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIROLIMUS; THROMBOPLASTIN;

EID: 46749091634     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH07-12-0722     Document Type: Article

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