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Volumn 156, Issue 1-2, 2004, Pages 42-57

A monoclonal antibody to CD11d reduces the inflammatory infiltrate into the injured spinal cord: A potential neuroprotective treatment

Author keywords

beta; 2 integrin; CD11dCD18; Inflammation; Methylprednisolone; Spinal cord injury

Indexed keywords

ALLOANTIGEN; CD11 ANTIGEN; CD11D ANTIGEN; CD18 ANTIGEN; INTEGRIN; METHYLPREDNISOLONE SODIUM SUCCINATE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD11D; NEUROPROTECTIVE AGENT; UNCLASSIFIED DRUG;

EID: 4644342939     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2004.07.002     Document Type: Article
Times cited : (118)

References (75)
  • 1
    • 1642358379 scopus 로고    scopus 로고
    • Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats
    • F. Bao, Y. Chen, G. Dekaban, and L.C. Weaver Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats J. Neurochem. 88 2004 1335 1344
    • (2004) J. Neurochem. , vol.88 , pp. 1335-1344
    • Bao, F.1    Chen, Y.2    Dekaban, G.3    Weaver, L.C.4
  • 2
    • 4444383094 scopus 로고    scopus 로고
    • An anti-CD11d integrin antibody reduces cyclooxygenase-2 expression and protein and DNA oxidation after spinal cord injury in rats
    • F. Bao, Y. Chen, G.A. Dekaban, and L.C. Weaver An anti-CD11d integrin antibody reduces cyclooxygenase-2 expression and protein and DNA oxidation after spinal cord injury in rats J. Neurochem. 90 2004 1194 1204
    • (2004) J. Neurochem. , vol.90 , pp. 1194-1204
    • Bao, F.1    Chen, Y.2    Dekaban, G.A.3    Weaver, L.C.4
  • 3
    • 0028795058 scopus 로고
    • Methylprednisolone inhibits early inflammatory processes but not ischemic cell death after experimental spinal cord lesion in the rat
    • D. Bartholdi, and M.E. Schwab Methylprednisolone inhibits early inflammatory processes but not ischemic cell death after experimental spinal cord lesion in the rat Brain Res. 672 1995
    • (1995) Brain Res. , vol.672
    • Bartholdi, D.1    Schwab, M.E.2
  • 4
    • 0032739262 scopus 로고    scopus 로고
    • Systemically administered interleukin-10 reduces tumor necrosis factor-alpha production and significantly improves functional recovery following traumatic spinal cord injury in rats
    • J.R. Bethea, H. Nagashima, M.C. Acosta, C. Briceno, F. Gomez, A.E. Marcillo, K. Loor, J. Green, and W.D. Dietrich Systemically administered interleukin-10 reduces tumor necrosis factor-alpha production and significantly improves functional recovery following traumatic spinal cord injury in rats J. Neurotrauma 16 1999 851 863
    • (1999) J. Neurotrauma , vol.16 , pp. 851-863
    • Bethea, J.R.1    Nagashima, H.2    Acosta, M.C.3    Briceno, C.4    Gomez, F.5    Marcillo, A.E.6    Loor, K.7    Green, J.8    Dietrich, W.D.9
  • 5
    • 0026575478 scopus 로고
    • Macrophages and inflammatory damage in spinal cord injury
    • A.R. Blight Macrophages and inflammatory damage in spinal cord injury J. Neurotrauma 9 1992 S83 S91
    • (1992) J. Neurotrauma , vol.9
    • Blight, A.R.1
  • 6
    • 0028331346 scopus 로고
    • Effects of silica on the outcome from experimental spinal cord injury: Implication of macrophages in secondary tissue damage
    • A.R. Blight Effects of silica on the outcome from experimental spinal cord injury: implication of macrophages in secondary tissue damage Neuroscience 60 1994 263 273
    • (1994) Neuroscience , vol.60 , pp. 263-273
    • Blight, A.R.1
  • 7
    • 0035893476 scopus 로고    scopus 로고
    • Methylprednisolone and acute spinal cord injury: An update of the randomized evidence
    • M.B. Bracken Methylprednisolone and acute spinal cord injury: an update of the randomized evidence Spine 26 2001 S47 S54
    • (2001) Spine , vol.26
    • Bracken, M.B.1
  • 10
    • 0033535952 scopus 로고    scopus 로고
    • Antibodies to CD44 and integrin alpha4, but not l-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment
    • S. Brocke, C. Piercy, L. Steinman, I.L. Weissman, and T. Veromaa Antibodies to CD44 and integrin alpha4, but not l-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment Proc. Natl. Acad. Sci. U. S. A. 96 1999 6896 6901
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 6896-6901
    • Brocke, S.1    Piercy, C.2    Steinman, L.3    Weissman, I.L.4    Veromaa, T.5
  • 11
    • 0030027461 scopus 로고    scopus 로고
    • Methods for determining numbers of cells and synapses: Case for more uniform standards of review
    • R.E. Coggeshall, and H.A. Lekan Methods for determining numbers of cells and synapses: case for more uniform standards of review J. Comp. Neurol. 364 1996 6 15
    • (1996) J. Comp. Neurol. , vol.364 , pp. 6-15
    • Coggeshall, R.E.1    Lekan, H.A.2
  • 14
    • 0041624586 scopus 로고    scopus 로고
    • Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway
    • R. Diem, M. Hobom, K. Maier, R. Weissert, M.K. Storch, R. Meyer, and M. Bahr Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway J. Neurosci. 23 2003 6993 7000
    • (2003) J. Neurosci. , vol.23 , pp. 6993-7000
    • Diem, R.1    Hobom, M.2    Maier, K.3    Weissert, R.4    Storch, M.K.5    Meyer, R.6    Bahr, M.7
  • 15
    • 0037312860 scopus 로고    scopus 로고
    • Novel glucocorticoid effects on acute inflammation in the CNS
    • K. Dinkel, A. MacPherson, and R.M. Sapolsky Novel glucocorticoid effects on acute inflammation in the CNS J. Neurochem. 84 2003 705 716
    • (2003) J. Neurochem. , vol.84 , pp. 705-716
    • Dinkel, K.1    MacPherson, A.2    Sapolsky, R.M.3
  • 16
    • 0031907089 scopus 로고    scopus 로고
    • Effects of intravenous methylprednisolone therapy on leukocyte and soluble adhesion molecule expression in MS
    • A.G. Droogan, A.D. Crockard, S.A. McMillan, and S.A. Hawkins Effects of intravenous methylprednisolone therapy on leukocyte and soluble adhesion molecule expression in MS Neurology 50 1998 224 230
    • (1998) Neurology , vol.50 , pp. 224-230
    • Droogan, A.G.1    Crockard, A.D.2    McMillan, S.A.3    Hawkins, S.A.4
  • 18
    • 0025161990 scopus 로고
    • VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site
    • M.J. Elices, L. Osborn, Y. Takada, C. Crouse, S. Luhowskyj, M.E. Hemler, and R.R. Lobb VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site Cell 60 1990 577 584
    • (1990) Cell , vol.60 , pp. 577-584
    • Elices, M.J.1    Osborn, L.2    Takada, Y.3    Crouse, C.4    Luhowskyj, S.5    Hemler, M.E.6    Lobb, R.R.7
  • 19
    • 0033580040 scopus 로고    scopus 로고
    • Improved recovery after spinal cord trauma in ICAM-1 and P-selectin knockout mice
    • M. Farooque, J. Isaksson, and Y. Olsson Improved recovery after spinal cord trauma in ICAM-1 and P-selectin knockout mice NeuroReport 10 1999 131 134
    • (1999) NeuroReport , vol.10 , pp. 131-134
    • Farooque, M.1    Isaksson, J.2    Olsson, Y.3
  • 20
    • 0035893642 scopus 로고    scopus 로고
    • Editorial: Recommendations regarding the use of methylprednisolone in acute spinal cord injury: Making sense out of the controversy
    • M.G. Fehlings Editorial: recommendations regarding the use of methylprednisolone in acute spinal cord injury: making sense out of the controversy Spine 26 2001 S56 S57
    • (2001) Spine , vol.26
    • Fehlings, M.G.1
  • 21
    • 0029012783 scopus 로고
    • The relationships among the severity of spinal cord injury, residual neurological function, axon counts, and counts of retrogradely labeled neurons after experimental spinal cord injury
    • M.G. Fehlings, and C.H. Tator The relationships among the severity of spinal cord injury, residual neurological function, axon counts, and counts of retrogradely labeled neurons after experimental spinal cord injury Exp. Neurol. 132 1995 220 228
    • (1995) Exp. Neurol. , vol.132 , pp. 220-228
    • Fehlings, M.G.1    Tator, C.H.2
  • 22
    • 0032006114 scopus 로고    scopus 로고
    • Effects of macrophage transplantation in the injured rat spinal cord: A combined immunocytochemical and biochemical study
    • R. Franzen, J. Schoenen, P. Leprince, E. Joosten, G. Moonen, and D. Martin Effects of macrophage transplantation in the injured rat spinal cord: a combined immunocytochemical and biochemical study J. Neurosci. Res. 51 1998 316 327
    • (1998) J. Neurosci. Res. , vol.51 , pp. 316-327
    • Franzen, R.1    Schoenen, J.2    Leprince, P.3    Joosten, E.4    Moonen, G.5    Martin, D.6
  • 25
    • 0028791506 scopus 로고
    • Lymphocyte adhesion and transendothelial migration in the central nervous system: The role of LFA-1 ICAM-1, VLA-4 and VCAM-1
    • J. Greenwood, Y. Wang, and V.L. Calder Lymphocyte adhesion and transendothelial migration in the central nervous system: the role of LFA-1 ICAM-1, VLA-4 and VCAM-1 Immunology 86 1995 408 415
    • (1995) Immunology , vol.86 , pp. 408-415
    • Greenwood, J.1    Wang, Y.2    Calder, V.L.3
  • 26
    • 0026639936 scopus 로고
    • Optimisation of immunosuppressive therapy using pharmacokinetic principles
    • J. Grevel Optimisation of immunosuppressive therapy using pharmacokinetic principles Clin. Pharmacokinet. 23 1992 380 390
    • (1992) Clin. Pharmacokinet. , vol.23 , pp. 380-390
    • Grevel, J.1
  • 27
    • 2142821430 scopus 로고    scopus 로고
    • Transient blockade of the CD11D/CD18 intregrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function
    • D. Gris, D.R. Marsh, M.A. Oatway, Y. Chen, E.F. Hamilton, G.A. Dekaban, and L.C. Weaver Transient blockade of the CD11D/CD18 intregrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function J. Neurosci. 24 2004 4043 4051
    • (2004) J. Neurosci. , vol.24 , pp. 4043-4051
    • Gris, D.1    Marsh, D.R.2    Oatway, M.A.3    Chen, Y.4    Hamilton, E.F.5    Dekaban, G.A.6    Weaver, L.C.7
  • 28
    • 0026500593 scopus 로고
    • The neuroprotective pharmacology of methylprednisolone
    • E.D. Hall The neuroprotective pharmacology of methylprednisolone J. Neurol. 76 1992 13 22
    • (1992) J. Neurol. , vol.76 , pp. 13-22
    • Hall, E.D.1
  • 29
    • 0023752162 scopus 로고
    • New pharmacological treatment of acute spinal cord trauma
    • E.D. Hall, J.M. Braughler, and J.M. McCall New pharmacological treatment of acute spinal cord trauma J. Neurotrauma 5 1988 81 89
    • (1988) J. Neurotrauma , vol.5 , pp. 81-89
    • Hall, E.D.1    Braughler, J.M.2    McCall, J.M.3
  • 30
    • 0029983883 scopus 로고    scopus 로고
    • Involvement of an intercellular adhesion molecule 1-dependent pathway in the pathogenesis of secondary changes after spinal cord injury in rats
    • Y. Hamada, T. Ikata, S. Katoh, K. Kauchi, M. Wa, Y. Wai, and K. Kuzawa Involvement of an intercellular adhesion molecule 1-dependent pathway in the pathogenesis of secondary changes after spinal cord injury in rats J. Neurochem. 66 1996 1525 1531
    • (1996) J. Neurochem. , vol.66 , pp. 1525-1531
    • Hamada, Y.1    Ikata, T.2    Katoh, S.3    Kauchi, K.4    Wa, M.5    Wai, Y.6    Kuzawa, K.7
  • 31
    • 0038340422 scopus 로고    scopus 로고
    • Post-traumatic inflammation following spinal cord injury
    • O.N. Hausmann Post-traumatic inflammation following spinal cord injury Spinal Cord 41 2003 369 378
    • (2003) Spinal Cord , vol.41 , pp. 369-378
    • Hausmann, O.N.1
  • 32
    • 0043172315 scopus 로고    scopus 로고
    • Glucocorticoid-mediated regulation of granulocyte apoptosis and macrophage phagocytosis of apoptotic cells: Implications for the resolution of inflammation
    • S.J. Heasman, K.M. Giles, C. Ward, A.G. Rossi, C. Haslett, and I. Dransfield Glucocorticoid-mediated regulation of granulocyte apoptosis and macrophage phagocytosis of apoptotic cells: implications for the resolution of inflammation J. Endocrinol. 178 2003 29 36
    • (2003) J. Endocrinol. , vol.178 , pp. 29-36
    • Heasman, S.J.1    Giles, K.M.2    Ward, C.3    Rossi, A.G.4    Haslett, C.5    Dransfield, I.6
  • 33
    • 0034141445 scopus 로고    scopus 로고
    • Sequential binding of CD11a/CD18 and CD11b/CD18 defines neutrophil capture and stable adhesion to intercellular adhesion molecule-1
    • E.R. Hentzen, S. Neelamegham, G.S. Kansas, J.A. Benanti, L.V. McIntire, C.W. Smith, and S.I. Simon Sequential binding of CD11a/CD18 and CD11b/CD18 defines neutrophil capture and stable adhesion to intercellular adhesion molecule-1 Blood 95 2000 911 920
    • (2000) Blood , vol.95 , pp. 911-920
    • Hentzen, E.R.1    Neelamegham, S.2    Kansas, G.S.3    Benanti, J.A.4    McIntire, L.V.5    Smith, C.W.6    Simon, S.I.7
  • 34
    • 0037059768 scopus 로고    scopus 로고
    • The NMDA receptor splice variant NR1-4 C-terminal domain: Deletion analysis and role in subcellular distribution
    • K.D. Holmes, P.A. Mattar, D.R. Marsh, L.C. Weaver, and G.A. Dekaban The NMDA receptor splice variant NR1-4 C-terminal domain: deletion analysis and role in subcellular distribution J. Biol. Chem. 277 2001 1457 1468
    • (2001) J. Biol. Chem. , vol.277 , pp. 1457-1468
    • Holmes, K.D.1    Mattar, P.A.2    Marsh, D.R.3    Weaver, L.C.4    Dekaban, G.A.5
  • 35
    • 0037738758 scopus 로고    scopus 로고
    • Methylprednisolone for acute spinal cord injury: Not a standard of care
    • H. Hugenholtz Methylprednisolone for acute spinal cord injury: not a standard of care CMAJ 168 2003 1145 1146
    • (2003) CMAJ , vol.168 , pp. 1145-1146
    • Hugenholtz, H.1
  • 36
    • 0028072846 scopus 로고
    • Immunosuppression to cardiac allografts and soluble antigens by anti-vascular cellular adhesion molecule-1 and anti-very late antigen-4 monoclonal antibodies
    • M. Isobe, J. Suzuki, H. Yagita, K. Okumura, S. Yamazaki, R. Nagai, Y. Yazaki, and M. Sekiguchi Immunosuppression to cardiac allografts and soluble antigens by anti-vascular cellular adhesion molecule-1 and anti-very late antigen-4 monoclonal antibodies J. Immunol. 153 1994 5810 5818
    • (1994) J. Immunol. , vol.153 , pp. 5810-5818
    • Isobe, M.1    Suzuki, J.2    Yagita, H.3    Okumura, K.4    Yamazaki, S.5    Nagai, R.6    Yazaki, Y.7    Sekiguchi, M.8
  • 37
    • 0030035865 scopus 로고    scopus 로고
    • Treatment of established adjuvant arthritis in rats with monoclonal antibody to CD18 and very late activation antigen-4 integrins suppresses neutrophil and T-lymphocyte migration to the joints and improves clinical disease
    • A.C. Issekutz, L. Ayer, M. Miyasaka, and T.B. Issekutz Treatment of established adjuvant arthritis in rats with monoclonal antibody to CD18 and very late activation antigen-4 integrins suppresses neutrophil and T-lymphocyte migration to the joints and improves clinical disease Immunology 88 1996 569 576
    • (1996) Immunology , vol.88 , pp. 569-576
    • Issekutz, A.C.1    Ayer, L.2    Miyasaka, M.3    Issekutz, T.B.4
  • 39
    • 0035449479 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor deletion reduces nuclear factor-kappaB activation, cellular inhibitor of apoptosis protein 2 expression, and functional recovery after traumatic spinal cord injury
    • G.M. Kim, J. Xu, J. Xu, S.K. Song, P. Yan, G. Ku, X.M. Xu, and C.Y. Hsu Tumor necrosis factor receptor deletion reduces nuclear factor-kappaB activation, cellular inhibitor of apoptosis protein 2 expression, and functional recovery after traumatic spinal cord injury J. Neurosci. 21 2001 6617 6625
    • (2001) J. Neurosci. , vol.21 , pp. 6617-6625
    • Kim, G.M.1    Xu, J.2    Xu, J.3    Song, S.K.4    Yan, P.5    Ku, G.6    Xu, X.M.7    Hsu, C.Y.8
  • 40
    • 0030746939 scopus 로고    scopus 로고
    • Effects of pro-inflammatory cytokines in experimental spinal cord injury
    • I. Klusman, and M.E. Schwab Effects of pro-inflammatory cytokines in experimental spinal cord injury Brain Res. 762 1997 173 184
    • (1997) Brain Res. , vol.762 , pp. 173-184
    • Klusman, I.1    Schwab, M.E.2
  • 41
    • 0030903015 scopus 로고    scopus 로고
    • Effect of a single huge dose of methylprednisolone on blood flow, evoked potentials, and histology after acute spinal cord injury in the rat
    • I. Koyanagi, and C.H. Tator Effect of a single huge dose of methylprednisolone on blood flow, evoked potentials, and histology after acute spinal cord injury in the rat Neurol. Res. 19 1997 289 299
    • (1997) Neurol. Res. , vol.19 , pp. 289-299
    • Koyanagi, I.1    Tator, C.H.2
  • 42
    • 0032981648 scopus 로고    scopus 로고
    • Adhesion molecule expression and regulation on cells of the central nervous system
    • S.J. Lee, and E.N. Benveniste Adhesion molecule expression and regulation on cells of the central nervous system J. Neuroimmunol. 98 1999 77 88
    • (1999) J. Neuroimmunol. , vol.98 , pp. 77-88
    • Lee, S.J.1    Benveniste, E.N.2
  • 44
    • 0033756931 scopus 로고    scopus 로고
    • Inhibition of monocyte/macrophage migration to a spinal cord injury site by an antibody to the integrin alphaD: A potential new anti-inflammatory treatment
    • P.J. Mabon, L.C. Weaver, and G.A. Dekaban Inhibition of monocyte/macrophage migration to a spinal cord injury site by an antibody to the integrin alphaD: a potential new anti-inflammatory treatment Exp. Neurol. 166 2000 52 64
    • (2000) Exp. Neurol. , vol.166 , pp. 52-64
    • Mabon, P.J.1    Weaver, L.C.2    Dekaban, G.A.3
  • 45
    • 0034662134 scopus 로고    scopus 로고
    • VLA-4 (alpha(4)beta(1)) engagement defines a novel activation pathway for beta(2) integrin-dependent leukocyte adhesion involving the urokinase receptor
    • A.E. May, F.J. Neumann, A. Schomig, and K.T. Preissner VLA-4 (alpha(4)beta(1)) engagement defines a novel activation pathway for beta(2) integrin-dependent leukocyte adhesion involving the urokinase receptor Blood 96 2000 506 513
    • (2000) Blood , vol.96 , pp. 506-513
    • May, A.E.1    Neumann, F.J.2    Schomig, A.3    Preissner, K.T.4
  • 46
    • 0019445085 scopus 로고
    • Effect of methylprednisolone in compression trauma to the feline spinal cord
    • E.D. Means, D.K. Anderson, T.R. Waters, and L. Kalaf Effect of methylprednisolone in compression trauma to the feline spinal cord J. Neurosurg. 55 1981 200 208
    • (1981) J. Neurosurg. , vol.55 , pp. 200-208
    • Means, E.D.1    Anderson, D.K.2    Waters, T.R.3    Kalaf, L.4
  • 48
    • 1842867217 scopus 로고    scopus 로고
    • Expression of the myeloid-specific leukocyte integrin gene CD11d during macrophage foam cell differentiation and exposure to lipoproteins
    • J.D. Noti Expression of the myeloid-specific leukocyte integrin gene CD11d during macrophage foam cell differentiation and exposure to lipoproteins Int. J. Mol. Med. 10 2002 721 727
    • (2002) Int. J. Mol. Med. , vol.10 , pp. 721-727
    • Noti, J.D.1
  • 49
    • 0030222129 scopus 로고    scopus 로고
    • Nerve growth factor promotes regeneration of sensory axons into adult rat spinal cord
    • M. Oudega, and T. Hagg Nerve growth factor promotes regeneration of sensory axons into adult rat spinal cord Exp. Neurol. 140 1996 218 229
    • (1996) Exp. Neurol. , vol.140 , pp. 218-229
    • Oudega, M.1    Hagg, T.2
  • 50
    • 0034946614 scopus 로고    scopus 로고
    • Bone marrow chimeric rats reveal the unique distribution of resident and recruited macrophages in the contused rat spinal cord
    • P.G. Popovich, and W.F. Hickey Bone marrow chimeric rats reveal the unique distribution of resident and recruited macrophages in the contused rat spinal cord J. Neuropathol. Exp. Neurol. 60 2001 676 685
    • (2001) J. Neuropathol. Exp. Neurol. , vol.60 , pp. 676-685
    • Popovich, P.G.1    Hickey, W.F.2
  • 51
    • 0037216605 scopus 로고    scopus 로고
    • Manipulating neuroinflammatory reactions in the injured spinal cord: Back to basics
    • P.G. Popovich, and T.B. Jones Manipulating neuroinflammatory reactions in the injured spinal cord: back to basics Trends Pharmacol. Sci. 24 2003 13 17
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 13-17
    • Popovich, P.G.1    Jones, T.B.2
  • 52
    • 0032838089 scopus 로고    scopus 로고
    • Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury
    • P.G. Popovich, Z. Guan, P. Wei, I. Huitinga, R.N. van, and B.T. Stokes Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury Exp. Neurol. 158 1999 351 365
    • (1999) Exp. Neurol. , vol.158 , pp. 351-365
    • Popovich, P.G.1    Guan, Z.2    Wei, P.3    Huitinga, I.4    Van, R.N.5    Stokes, B.T.6
  • 54
    • 0031427380 scopus 로고    scopus 로고
    • Activated macrophage/microglial cells can promote the regeneration of sensory axons into the injured spinal cord
    • C.M.F. Prewitt, I.R. Niesman, C.J.M. Kane, and J.D. Houle Activated macrophage/microglial cells can promote the regeneration of sensory axons into the injured spinal cord Exp. Neurol. 148 1997 433 443
    • (1997) Exp. Neurol. , vol.148 , pp. 433-443
    • Prewitt, C.M.F.1    Niesman, I.R.2    Kane, C.J.M.3    Houle, J.D.4
  • 55
    • 0031022698 scopus 로고    scopus 로고
    • Grafting of cultured microglial cells into the lesioned spinal cord of adult rats enhances neurite outgrowth
    • A.G. Rabchevsky, and W.J. Streit Grafting of cultured microglial cells into the lesioned spinal cord of adult rats enhances neurite outgrowth J. Neurosci. Res. 47 1997 34 48
    • (1997) J. Neurosci. Res. , vol.47 , pp. 34-48
    • Rabchevsky, A.G.1    Streit, W.J.2
  • 58
    • 0024536234 scopus 로고
    • Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages
    • J.S. Savill, A.H. Wyllie, J.E. Henson, M.J. Walport, P.M. Henson, and C. Haslett Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages J. Clin. Invest. 83 1989 865 875
    • (1989) J. Clin. Invest. , vol.83 , pp. 865-875
    • Savill, J.S.1    Wyllie, A.H.2    Henson, J.E.3    Walport, M.J.4    Henson, P.M.5    Haslett, C.6
  • 60
    • 0037385159 scopus 로고    scopus 로고
    • Ages and microglia in central nervous system injury: Are they helpful or harmful?
    • M. Schwartz ages and microglia in central nervous system injury: are they helpful or harmful? J. Cereb. Blood Flow Metab. 23 2003 385 394
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 385-394
    • Schwartz, M.1
  • 62
    • 0027281360 scopus 로고
    • Endothelial adhesion molecules and their role in inflammation
    • C.W. Smith Endothelial adhesion molecules and their role in inflammation Can. J. Physiol. Pharm. 71 1993 76 87
    • (1993) Can. J. Physiol. Pharm. , vol.71 , pp. 76-87
    • Smith, C.W.1
  • 64
    • 0031815256 scopus 로고    scopus 로고
    • Cytokine mRNA profiles in contused spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis
    • W.J. Streit, S.L. Semple-Rowland, S.D. Hurley, R.C. Miller, P.G. Popovich, and B.T. Stokes Cytokine mRNA profiles in contused spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis Exp. Neurol. 152 1998 74 87
    • (1998) Exp. Neurol. , vol.152 , pp. 74-87
    • Streit, W.J.1    Semple-Rowland, S.L.2    Hurley, S.D.3    Miller, R.C.4    Popovich, P.G.5    Stokes, B.T.6
  • 65
    • 0031817692 scopus 로고    scopus 로고
    • Spinal cord injury in the rat
    • Y. Taoka, and K. Okajima Spinal cord injury in the rat Prog. Neurobiol. 56 1998 341 358
    • (1998) Prog. Neurobiol. , vol.56 , pp. 341-358
    • Taoka, Y.1    Okajima, K.2
  • 67
    • 0037258442 scopus 로고    scopus 로고
    • Isolation of rat Kupffer cells: A combined methodology for highly purified primary cultures
    • V. Valatas, C. Xidakis, M. Roumpaki, G. Kolios, and E.A. Kouroumalis Isolation of rat Kupffer cells: a combined methodology for highly purified primary cultures Cell Biol. Int. 27 2003 67 73
    • (2003) Cell Biol. Int. , vol.27 , pp. 67-73
    • Valatas, V.1    Xidakis, C.2    Roumpaki, M.3    Kolios, G.4    Kouroumalis, E.A.5
  • 70
    • 0027156167 scopus 로고
    • Impairment of function in aging neutrophils is associated with apoptosis
    • M.K. Whyte, L.C. Meagher, J. MacDermot, and C. Haslett Impairment of function in aging neutrophils is associated with apoptosis J. Immunol. 150 1993 5124 5134
    • (1993) J. Immunol. , vol.150 , pp. 5124-5134
    • Whyte, M.K.1    Meagher, L.C.2    MacDermot, J.3    Haslett, C.4
  • 71
    • 0032584936 scopus 로고    scopus 로고
    • Methylprednisolone inhibition of TNF-alpha expression and NF-kB activation after spinal cord injury in rats
    • J. Xu, G. Fan, S. Chen, Y. Wu, X.M. Xu, and C.Y. Hsu Methylprednisolone inhibition of TNF-alpha expression and NF-kB activation after spinal cord injury in rats Brain Res. Mol. Brain Res. 59 1998 135 142
    • (1998) Brain Res. Mol. Brain Res. , vol.59 , pp. 135-142
    • Xu, J.1    Fan, G.2    Chen, S.3    Wu, Y.4    Xu, X.M.5    Hsu, C.Y.6
  • 72
    • 0032192489 scopus 로고    scopus 로고
    • Hu23F2G, an antibody recognizing the leukocyte CD11/CD18 integrin, reduces injury in a rabbit model of transient focal cerebral ischemia
    • Q. Yenari, D. Kunis, G.H. Sun, D. Onley, L. Watson, S. Turner, S. Whitaker, and G.K. Steinberg Hu23F2G, an antibody recognizing the leukocyte CD11/CD18 integrin, reduces injury in a rabbit model of transient focal cerebral ischemia Exp. Neurol. 153 1998 223 233
    • (1998) Exp. Neurol. , vol.153 , pp. 223-233
    • Yenari, Q.1    Kunis, D.2    Sun, G.H.3    Onley, D.4    Watson, L.5    Turner, S.6    Whitaker, S.7    Steinberg, G.K.8
  • 73
    • 0019960776 scopus 로고
    • Effect of high-dose corticosteroid therapy on blood flow, evoked potentials, and extracellular calcium in experimental spinal injury
    • W. Young, and E.S. Flamm Effect of high-dose corticosteroid therapy on blood flow, evoked potentials, and extracellular calcium in experimental spinal injury J. Neurosurg. 57 1982 667 673
    • (1982) J. Neurosurg. , vol.57 , pp. 667-673
    • Young, W.1    Flamm, E.S.2
  • 74
    • 0023782824 scopus 로고
    • Pharmacological therapy of acute spinal cord injury: Studies of high dose methylprednisolone and naloxone
    • W. Young, V. DeCrescito, E.S. Flamm, A.R. Blight, and J.A. Gruner Pharmacological therapy of acute spinal cord injury: studies of high dose methylprednisolone and naloxone Clin. Neurosurg. 33 1988 675 697
    • (1988) Clin. Neurosurg. , vol.33 , pp. 675-697
    • Young, W.1    Decrescito, V.2    Flamm, E.S.3    Blight, A.R.4    Gruner, J.A.5
  • 75
    • 0031033377 scopus 로고    scopus 로고
    • Experimental analysis of progressive necrosis after spinal cord trauma in the rat: Etiological role of the inflammatory response
    • Z. Zhang, C.J. Krebs, and L. Guth Experimental analysis of progressive necrosis after spinal cord trauma in the rat: etiological role of the inflammatory response Exp. Neurol. 143 1997 141 152
    • (1997) Exp. Neurol. , vol.143 , pp. 141-152
    • Zhang, Z.1    Krebs, C.J.2    Guth, L.3


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