Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway

Journal of Neuroscience

Volumn 23, Issue 18, 2003, Pages 6993-7000

  Diem, Ricarda ^a   Hobom, Muriel ^a   Maier, Katharina ^a   Weissert, Robert ^b   Storch, Maria K ^c   Meyer, Roman ^b,d   Bähr, Mathias ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

^d Profos GmbH   (Germany)

Author keywords

Electroretinogram; Experimental autoimmune encephalomyelitis; Glucocorticosteroids; Mitogen activated kinases; Retinal ganglion cells; Visual evoked potentials

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CALCIUM; COBALT CHLORIDE; METHYLPREDNISOLONE; MIFEPRISTONE; MITOGEN ACTIVATED PROTEIN KINASE; MYELIN OLIGODENDROCYTE GLYCOPROTEIN;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CELL FUNCTION; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DRUG MECHANISM; DRUG SAFETY; ELECTRORETINOGRAPHY; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; EVOKED VISUAL RESPONSE; FEMALE; MOLECULAR DYNAMICS; NERVE CELL NECROSIS; NERVE FIBER; NERVOUS SYSTEM INFLAMMATION; NEUROPHYSIOLOGY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OPTIC NERVE; OPTIC NERVE DISEASE; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL; WESTERN BLOTTING;

EID: 0041624586     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-18-06993.2003     Document Type: Article

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