The leukocyte integrin α(D)β2 binds VCAM-1: Evidence for a binding interface between I domain and VCAM-1

Journal of Immunology

Volumn 163, Issue 4, 1999, Pages 1984-1990

  Van Der Vieren, Monica ^a   Crowe, David T ^a   Hoekstra, Denise ^a   Vazeux, Rosemay ^a   Hoffman, Patricia A ^a   Grayson, Mitchell H ^b   Bochner, Bruce S ^b   Gallatin, W Michael ^a   Staunton, Donald E ^a  

^a ELI LILLY AND COMPANY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD18 ANTIGEN; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MUTANT PROTEIN; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ARTICLE; CELL ADHESION; CELL SUBPOPULATION; CONTROLLED STUDY; EOSINOPHIL; HUMAN; HUMAN CELL; LEUKOCYTE MIGRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

ANIMALS; ANTIBODIES, BLOCKING; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD11; BINDING SITES; BINDING SITES, ANTIBODY; CELL ADHESION; CELL MOVEMENT; HUMANS; INTEGRIN ALPHA CHAINS; INTEGRIN ALPHA4; INTEGRINS; JURKAT CELLS; LEUKOCYTES; MICE; MICE, INBRED BALB C; PEPTIDE FRAGMENTS; PROTEIN BINDING; RECEPTORS, CYTOADHESIN; RECOMBINANT PROTEINS; RHEOLOGY; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0033566675     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Butcher, E. C., and L. J. Picker. 1996. Lymphocyte homing and homeostasis. Science 272:60.
2. Butcher, B.C. 1991. Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67:1033.
3. Springer, T. A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76:301.
4. 4 integrins mediate lymphocyte attachment and rolling under physiologic flow. Cell 80:413.
5. Alon, R., P. D. Kassner, M. W. Carr, E. B. Finger, M. E. Hemler, and T. A. Springer. 1995. The integrin VLA-4 supports tethering and rolling in flow on VCAM-1. J. Cell Biol. 128:1243.
6. Colombatti, A., and P. Bonaldo. 1991. The superfamily of proteins with von Willebrand factor type A-like domains: one theme common to components of extracellular matrix, hemostasis, cellular adhesion, and defense mechanisms. Blood 77:2305.
7. Lee, J. O., P. Rieu, M. A. Arnaout, and R. Liddington. 1995. Crystal structure of the A domain from the α-subunit of integrin CR3 (CD11b/CD18). Cell 80:631.
8. 2) integrin. Proc. Natl. Acad. Sci. USA 92:10277.
9. Diamond, M. S., J. Garcia-Aguilar, J. K. Bickford, A. L. Corbi, and T. A. Springer. 1993. The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands. J. Cell Biol. 120:1031.
10. 2 integrin lymphocyte function-associated antigen-1 contains a binding site for ligand intercellular adhesion molecule-1. J. biol. Chem. 269:12395.
11. Stanley, P., and N. Hogg. 1998. The I domain of integrin LFA-1 interacts with ICAM-1 domain 1 at residue Glu-34 but not Gln-73. J. Biol. Chem. 273:3358.
12. Edwards, C. P., M. Champe, T. Gonzalez, M. E. Wessinger, S. A. Spencer, L. G. Presta, P. W. Berman, and S. C. Bodary. 1995. Identification of amino acids in the CD11a I-domain important for binding of the leukocyte function-associated antigen-1 (LFA-1) to intercellular adhesion molecule-1 (ICAM-1). J. Biol. Chem. 270:12635.
13. Huang, C., and T. A. Springer. 1995. A binding interface on the I domain of lymphocyte function-associated antigen-1 (LFA-1) required for specific interaction with intercellular adhesion molecule 1 (ICAM-1). J. Biol. Chem. 270:19008.
14. 2 integrins for interactions with intercellular adhesion molecule 1 (ICAM-1) and C3bi. J. Biol. Chem. 270:12531.
15. Staunton, D. E., M. L. Dustin, H. P. Erickson, and T. A. Springer. 1990. The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus [published errata appear in Cell 1990 61:1157 and 1991 66:1311]. Cell 61:243.
16. Sadhu, C., B. Lipsky, H. P. Erickson, J. Hayflick, K. O. Dick, W. M. Gallatin, and D. E. Staunton. 1994. LFA-1 binding site in ICAM-3 contains a conserved motif and non-contiguous amino acids. Cell Adhes. Commun. 2:429.
17. 4 subunit in the upper face of the β-propeller mode 1. Proc. Natl. Acad. Sci. USA 94:7198.
18. Vonderheide, R. H., T. F. Tedder, T. A. Springer, and D. E. Staunton. 1994. Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4. J. Cell Biol. 125:215.
19. 2 ligand interactions. J. Biol. Chem. 271:23729.
20. Atherton, A., and G. V. Born. 1972. Quantitative investigations of the adhesiveness of circulating polymorphonuclear leucocytes to blood vessel walls. J. Physiol. 222:447.
21. Perry, M. A., and D. N. Granger. 1991. Role of CD11/CD18 in shear rate-dependent leukocyte-endothelial cell interactions in cat mesenteric venules. J. Clin. Invest. 87:1798.
22. Lawrence, M. B., and T. A. Springer. 1991. Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell 65:859.
23. 2, binds preferentially to ICAM-3. Immunity 3:683.
24. 2) on human leukocytes and mast cells. J. Allergy Clin. Immunol. 99:5386.
25. 2 integrin is expressed on human eosinophils and functions as an alternative ligand for vascular cell adhesion molecule 1 (VCAM-1). J. Exp. Med. 188:2187.
26. Harlow, E. 1988. Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, p. xiii.
27. Myszka, D. G. 1997. Kinetic analysis of macromolecular interactions using surface plasmon resonance biosensors. Curr. Opin. Biotechnol. 8:50.
28. Casasnovas, J. M., T. Stehle, J. H. Liu, J. H. Wang, and T. A. Springer. 1998. A dimeric crystal structure for the N-terminal two domains of intercellular adhesion molecule-1. Proc. Natl. Acad. Sci. USA 95:4134.
29. 1). J. Cell Biol. 124:601.
30. 4 integrin binding interfaces on VCAM-1 and MAdCAM-1 : integrin binding footprints identify accessory binding sites that play a role in integrin specificity. J. Biol. Chem. 272:19429.
31. Klickstein, L. B., M. R. York, A. R. Fougerolles, and T. A. Springer. 1996. Localization of the binding site on intercellular adhesion molecule-3 (ICAM-3) for lymphocyte function-associated antigen 1 (LFA-1). J. Biol. Chem. 271:23920.
32. Aoki, T., Y. Suzuki, K. Nishio, K. Suzuki, A. Miyata, Y. Iigou, H. Serizawa, H. Tsumura, Y. Ishimura, M. Suematsu, et al. 1997. Role of CD18-ICAM-1 in the entrapment of stimulated leukocytes in alveolar capillaries of perfused rat lungs. Am. J. Physiol. 273:H2361.
33. Worthen, G. S., L. A. Smedly, M. G. Tonnesen, D. Ellis, N. F. Voelkel, J. T. Reeves, and P. M. Henson. 1987. Effects of shear stress on adhesive interaction between neutrophils and cultured endothelial cells. J. Appl. Physiol. 63: 2031.
34. Schweitzer, K. M., A. M. Drager, P. van der Valk. S. F. Thijsen, A. Zevenbergen, A. P. Theijsmeijer, C. E. van der School, and M. M. Langenhuijsen. 1996. Constitutive expression of E-selectin and vascular cell adhesion molecule-1 on endothelial cells of hematopoietic tissues. Am. J. Pathol. 148:165.