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Volumn 762, Issue 1-2, 1997, Pages 173-184

Effects of pro-inflammatory cytokines in experimental spinal cord injury

Author keywords

Central nervous system; Interleukin 1 ; Interleukin 6; Macrophage invasion; Secondary damage; Spinal cord injury; Tumor necrosis factor

Indexed keywords

INTERLEUKIN 6; RECOMBINANT INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 0030746939     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00381-8     Document Type: Article
Times cited : (173)

References (64)
  • 1
    • 0025253851 scopus 로고
    • Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF)
    • Akira S., Hirano T., Taga T., Kishimoto T. Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF). FASEB J. 4:1990;2860-2867.
    • (1990) FASEB J. , vol.4 , pp. 2860-2867
    • Akira, S.1    Hirano, T.2    Taga, T.3    Kishimoto, T.4
  • 2
    • 0027288332 scopus 로고
    • Pathophysiology of spinal cord trauma
    • Anderson D.K., Hall E.D. Pathophysiology of spinal cord trauma. Ann. Emerg. Med. 22:1993;987-992.
    • (1993) Ann. Emerg. Med. , vol.22 , pp. 987-992
    • Anderson, D.K.1    Hall, E.D.2
  • 3
    • 0028012270 scopus 로고
    • Reactive astrogliosis in the neonatal mouse brain and its modulation by cytokines
    • Balasingam V., Tejada-Berges T., Wright E., Bouckova R., Yong V.W. Reactive astrogliosis in the neonatal mouse brain and its modulation by cytokines. J. Neurosci. 4:1994;846-856.
    • (1994) J. Neurosci. , vol.4 , pp. 846-856
    • Balasingam, V.1    Tejada-Berges, T.2    Wright, E.3    Bouckova, R.4    Yong, V.W.5
  • 5
    • 0025173499 scopus 로고
    • Regional and cellular codistribution of interleukin 1 beta and nerve growth factor mRNA in the adult rat brain: Possible relationship to the regulation of nerve growth factor synthesis
    • Bandtlow C.E., Meyer M., Lindholm D., Spranger M., Heumann R., Thoenen H. Regional and cellular codistribution of interleukin 1 beta and nerve growth factor mRNA in the adult rat brain: possible relationship to the regulation of nerve growth factor synthesis. J. Cell Biol. 111:1990;1701-1711.
    • (1990) J. Cell Biol. , vol.111 , pp. 1701-1711
    • Bandtlow, C.E.1    Meyer, M.2    Lindholm, D.3    Spranger, M.4    Heumann, R.5    Thoenen, H.6
  • 6
    • 0028795058 scopus 로고
    • Methylprednisolone inhibits early inflammatory processes but not ischemic cell death after experimental spinal cord lesion in the rat
    • Bartholdi D., Schwab M.E. Methylprednisolone inhibits early inflammatory processes but not ischemic cell death after experimental spinal cord lesion in the rat. Brain Res. 672:1995;177-186.
    • (1995) Brain Res. , vol.672 , pp. 177-186
    • Bartholdi, D.1    Schwab, M.E.2
  • 7
    • 0030842973 scopus 로고    scopus 로고
    • Expression of cytokine and chemokine mRNA upon experimental spinal cord injury
    • in press
    • D. Bartholdi, M.E. Schwab, Expression of cytokine and chemokine mRNA upon experimental spinal cord injury, Eur. J. Neurosci. (1997) in press.
    • (1997) Eur. J. Neurosci.
    • Bartholdi, D.1    Schwab, M.E.2
  • 8
    • 0029784344 scopus 로고    scopus 로고
    • Recombinant human adenovirus with rat MIP-2 gene insertion causes prolonged PMN recruitment to the murine brain
    • Bell M.D., Taub D.D., Kunkel S.J., Streiter R.M., Foley R., Gauldie J., Perry V.H. Recombinant human adenovirus with rat MIP-2 gene insertion causes prolonged PMN recruitment to the murine brain. Eur. J. Neurosci. 8:1996;1803-1811.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1803-1811
    • Bell, M.D.1    Taub, D.D.2    Kunkel, S.J.3    Streiter, R.M.4    Foley, R.5    Gauldie, J.6    Perry, V.H.7
  • 9
    • 0029761934 scopus 로고    scopus 로고
    • Overriding the brain's intrinsic resistance to leukocyte recruitment with intraparenchymal injections of recombinant chemokines
    • Bell M.D., Taub D.D., Perry V.H. Overriding the brain's intrinsic resistance to leukocyte recruitment with intraparenchymal injections of recombinant chemokines. Neuroscience. 74:1996;282-292.
    • (1996) Neuroscience , vol.74 , pp. 282-292
    • Bell, M.D.1    Taub, D.D.2    Perry, V.H.3
  • 10
    • 0026575478 scopus 로고
    • Macrophages and inflammatory damage in spinal cord injury
    • Blight A.R. Macrophages and inflammatory damage in spinal cord injury. J. Neurotrauma. 9(Suppl. 1):1992;S83-S91.
    • (1992) J. Neurotrauma , vol.9 , Issue.SUPPL. 1
    • Blight, A.R.1
  • 12
    • 0027483753 scopus 로고
    • Distribution and characterization of tumor necrosis factor-alpha-like immunoreactivity in the murine central nervous system
    • Breder C.D., Tsjimoto M., Terano Y., Scott D.W., Saper C.B. Distribution and characterization of tumor necrosis factor-alpha-like immunoreactivity in the murine central nervous system. J. Comp. Neurol. 33:1993;543-567.
    • (1993) J. Comp. Neurol. , vol.33 , pp. 543-567
    • Breder, C.D.1    Tsjimoto, M.2    Terano, Y.3    Scott, D.W.4    Saper, C.B.5
  • 14
  • 15
    • 0029087348 scopus 로고
    • Modulation of human microglial cell superoxide production by cytokines
    • Chao C.C., Hu S., Peterson P.K. Modulation of human microglial cell superoxide production by cytokines. J. Leukocyte Biol. 58:1995;65-70.
    • (1995) J. Leukocyte Biol. , vol.58 , pp. 65-70
    • Chao, C.C.1    Hu, S.2    Peterson, P.K.3
  • 16
    • 0030108525 scopus 로고    scopus 로고
    • Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism
    • Chao C.C., Hu S., Sheng W.S., Bu D., Bukrinsky M.I., Peterson P.K. Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism. Glia. 16:1996;276-284.
    • (1996) Glia , vol.16 , pp. 276-284
    • Chao, C.C.1    Hu, S.2    Sheng, W.S.3    Bu, D.4    Bukrinsky, M.I.5    Peterson, P.K.6
  • 17
    • 0026470092 scopus 로고
    • A mechanism for the antiinflammatory effects of corticosteroids: The glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intracellular adhesion molecule 1
    • Cronstein B.N., Kimmel S.C., Levin R.I., Martiniuk F., Weissmann G. A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intracellular adhesion molecule 1. Proc. Natl. Acad. Sci. USA. 89:1992;9991-9995.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9991-9995
    • Cronstein, B.N.1    Kimmel, S.C.2    Levin, R.I.3    Martiniuk, F.4    Weissmann, G.5
  • 18
    • 0023231038 scopus 로고
    • Purification and characterization of human fibroblast-derived hybridoma growth factor identical to T-cell-derived B-cell stimulatory factor-2 (interleukin-6)
    • van Damme J., Cayphas S., van Snick J., Conings R., Put W., Lenaerts J.P., Simpson R.J., Billiau A. Purification and characterization of human fibroblast-derived hybridoma growth factor identical to T-cell-derived B-cell stimulatory factor-2 (interleukin-6). Eur. J. Biochem. 168:1987;543-550.
    • (1987) Eur. J. Biochem. , vol.168 , pp. 543-550
    • Van Damme, J.1    Cayphas, S.2    Van Snick, J.3    Conings, R.4    Put, W.5    Lenaerts, J.P.6    Simpson, R.J.7    Billiau, A.8
  • 20
    • 0028326548 scopus 로고
    • Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cord
    • Dusart I., Schwab M.E. Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cord. Eur. J. Neurosci. 6:1994;712-724.
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 712-724
    • Dusart, I.1    Schwab, M.E.2
  • 21
    • 0027314268 scopus 로고
    • Molecular profile of reactive astrocytes - implications for their role in neurologic disease
    • Eddleston M., Mucke L. Molecular profile of reactive astrocytes - implications for their role in neurologic disease. Neuroscience. 54:1993;15-36.
    • (1993) Neuroscience , vol.54 , pp. 15-36
    • Eddleston, M.1    Mucke, L.2
  • 24
    • 0020461752 scopus 로고
    • Production of prostaglandin E and interleukin 1-like factors by cultured astrocytes and C6 glioma cells
    • Fontana A., Kristensen F., Dubs R., Gemsa D., Weber E. Production of prostaglandin E and interleukin 1-like factors by cultured astrocytes and C6 glioma cells. J. Immunol. 129:1982;2413-2419.
    • (1982) J. Immunol. , vol.129 , pp. 2413-2419
    • Fontana, A.1    Kristensen, F.2    Dubs, R.3    Gemsa, D.4    Weber, E.5
  • 26
    • 0022441440 scopus 로고
    • Interleukin-1 of the central nervous system is produced by ameboid microglia
    • Giulian D., Baker T.J., Lachman L.B. Interleukin-1 of the central nervous system is produced by ameboid microglia. J. Exp. Med. 164:1986;594-604.
    • (1986) J. Exp. Med. , vol.164 , pp. 594-604
    • Giulian, D.1    Baker, T.J.2    Lachman, L.B.3
  • 29
    • 0030012410 scopus 로고    scopus 로고
    • The macrophage cell surface glycoprotein F4/80 is a highly glycosylated proteoglycan
    • Haidl I.D., Jefferies W.A. The macrophage cell surface glycoprotein F4/80 is a highly glycosylated proteoglycan. Eur. J. Immunol. 26:1996;1139-1146.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1139-1146
    • Haidl, I.D.1    Jefferies, W.A.2
  • 30
    • 0030054637 scopus 로고    scopus 로고
    • Activation and homologous desensitization of human endothelial cells by CD40 ligand, tumor necrosis factor, and interleukin 1
    • Karmann K., Min W., Fanslow W.C., Pober J.S. Activation and homologous desensitization of human endothelial cells by CD40 ligand, tumor necrosis factor, and interleukin 1. J. Exp. Med. 184:1996;173-182.
    • (1996) J. Exp. Med. , vol.184 , pp. 173-182
    • Karmann, K.1    Min, W.2    Fanslow, W.C.3    Pober, J.S.4
  • 31
    • 0029398824 scopus 로고
    • Intrathecal and serum interleukin-6 and the acute-phase response in patients with severe traumatic brain injuries
    • Kossmann T., Hans V.H., Imhof H.G., Stocker R., Grob P., Trentz O., Morganti-Kossmann C. Intrathecal and serum interleukin-6 and the acute-phase response in patients with severe traumatic brain injuries. Shock. 4:1995;311-317.
    • (1995) Shock , vol.4 , pp. 311-317
    • Kossmann, T.1    Hans, V.H.2    Imhof, H.G.3    Stocker, R.4    Grob, P.5    Trentz, O.6    Morganti-Kossmann, C.7
  • 33
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg G.W. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19:1996;312-318.
    • (1996) Trends Neurosci. , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 34
    • 0025437774 scopus 로고
    • Neutrophil attractant/activation protein-1 (NAP-1 [interleukin-8])
    • Leonard E.J., Yoshimura T. Neutrophil attractant/activation protein-1 (NAP-1 [interleukin-8]). Am. J. Respir. Cell. Mol. Biol. 2:1990;479-486.
    • (1990) Am. J. Respir. Cell. Mol. Biol. , vol.2 , pp. 479-486
    • Leonard, E.J.1    Yoshimura, T.2
  • 35
    • 0026563730 scopus 로고
    • Poly's lament: The neglected role of the polymorphonuclear neutrophil in the afferent limb of the immune system
    • Lloyd A.R., Oppenheim J.J. Poly's lament: the neglected role of the polymorphonuclear neutrophil in the afferent limb of the immune system. Immunol. Today. 13:1992;169-172.
    • (1992) Immunol. Today , vol.13 , pp. 169-172
    • Lloyd, A.R.1    Oppenheim, J.J.2
  • 36
    • 0026699984 scopus 로고
    • Enhanced expression of transforming growth factor β1 in the rat brain after a localized cerebral injury
    • Logan A., Frautschy S.A., Gonzalez A.M., Sporn M.B., Baird A. Enhanced expression of transforming growth factor β1 in the rat brain after a localized cerebral injury. Brain Res. 587:1992;216-225.
    • (1992) Brain Res. , vol.587 , pp. 216-225
    • Logan, A.1    Frautschy, S.A.2    Gonzalez, A.M.3    Sporn, M.B.4    Baird, A.5
  • 37
    • 0028230259 scopus 로고
    • Effects of transforming growth factor β1 on scar production in the injured central nervous system of the rat
    • Logan A., Berry M., Gonzalez A.M., Frautschy S.A., Sporn M.B., Baird A. Effects of transforming growth factor β1 on scar production in the injured central nervous system of the rat. Eur. J. Neurosci. 6:1994;355-363.
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 355-363
    • Logan, A.1    Berry, M.2    Gonzalez, A.M.3    Frautschy, S.A.4    Sporn, M.B.5    Baird, A.6
  • 39
    • 0030066172 scopus 로고    scopus 로고
    • Molecular cloning of F4/80, a murine macrophage-restricted cell surface glycoprotein with homology to the G-protein linked transmembrane 7 hormone receptor family
    • Mcknight A.J., Macfarlane A.J., Dri P., Turley L., Willis A.C., Gordon S. Molecular cloning of F4/80, a murine macrophage-restricted cell surface glycoprotein with homology to the G-protein linked transmembrane 7 hormone receptor family. J. Biol. Chem. 271:1996;486-489.
    • (1996) J. Biol. Chem. , vol.271 , pp. 486-489
    • Mcknight, A.J.1    Macfarlane, A.J.2    Dri, P.3    Turley, L.4    Willis, A.C.5    Gordon, S.6
  • 40
    • 0029029378 scopus 로고
    • Identification and characterization of a novel protein associated with macrophage complement receptor 3
    • Messika E.J., Avni O., Gallily R., Yefenof E., Baniyash M. Identification and characterization of a novel protein associated with macrophage complement receptor 3. J. Immunol. 154:1995;6563-6570.
    • (1995) J. Immunol. , vol.154 , pp. 6563-6570
    • Messika, E.J.1    Avni, O.2    Gallily, R.3    Yefenof, E.4    Baniyash, M.5
  • 42
    • 0023257978 scopus 로고
    • Interleukin-1-like activity in rat brain: Sources, targets and effect of injury
    • Nieto-Sampedro M., Berman M.A. Interleukin-1-like activity in rat brain: sources, targets and effect of injury. J. Neurosci. Res. 17:1987;214-219.
    • (1987) J. Neurosci. Res. , vol.17 , pp. 214-219
    • Nieto-Sampedro, M.1    Berman, M.A.2
  • 43
    • 0028868821 scopus 로고
    • Expression of the inducible isoform of nitric oxide synthase in the central nervous system of mice correlates with the severity of actively induced experimental allergic encephalomyelitis
    • Okuda Y., Nakatsuji Y., Fujimura H., Esumi H., Ogura T., Yanagihara T., Sakoda S. Expression of the inducible isoform of nitric oxide synthase in the central nervous system of mice correlates with the severity of actively induced experimental allergic encephalomyelitis. J. Neuroimmunol. 62:1995;103-112.
    • (1995) J. Neuroimmunol. , vol.62 , pp. 103-112
    • Okuda, Y.1    Nakatsuji, Y.2    Fujimura, H.3    Esumi, H.4    Ogura, T.5    Yanagihara, T.6    Sakoda, S.7
  • 44
    • 0028829601 scopus 로고
    • Cytokines in Alzheimer's disease and multiple sclerosis
    • Patterson P.H. Cytokines in Alzheimer's disease and multiple sclerosis. Curr. Opin. Neurobiol. 5:1995;642-646.
    • (1995) Curr. Opin. Neurobiol. , vol.5 , pp. 642-646
    • Patterson, P.H.1
  • 45
    • 0027245888 scopus 로고
    • Macrophages and inflammation in the central nervous system
    • Perry V.H., Anderson P.B., Gordon S. Macrophages and inflammation in the central nervous system. Trends Neurosci. 16:1993;268-273.
    • (1993) Trends Neurosci. , vol.16 , pp. 268-273
    • Perry, V.H.1    Anderson, P.B.2    Gordon, S.3
  • 46
    • 0028864801 scopus 로고
    • Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor α
    • Probert L., Akassoglou K., Pasparakis M., Kontogeorgos G., Kollias G. Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor α Proc. Natl. Acad. Sci. USA. 92:1995;11294-11298.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11294-11298
    • Probert, L.1    Akassoglou, K.2    Pasparakis, M.3    Kontogeorgos, G.4    Kollias, G.5
  • 47
    • 0029888888 scopus 로고    scopus 로고
    • Regulation of cytokine gene expression by reactive oxygen and reactive nitrogen intermediates
    • Remick D.G., Villarete L. Regulation of cytokine gene expression by reactive oxygen and reactive nitrogen intermediates. J. Leukocyte Biol. 59:1996;471-475.
    • (1996) J. Leukocyte Biol. , vol.59 , pp. 471-475
    • Remick, D.G.1    Villarete, L.2
  • 50
    • 0026076534 scopus 로고
    • Functions and mechanisms of interleukin 1 in the brain
    • Rothwell N.J. Functions and mechanisms of interleukin 1 in the brain. Trends Pharmacol. Sci. 12:1991;430-436.
    • (1991) Trends Pharmacol. Sci. , vol.12 , pp. 430-436
    • Rothwell, N.J.1
  • 51
    • 0028069629 scopus 로고
    • CNS regulation of thermogenesis
    • Rothwell N.J. CNS regulation of thermogenesis. Crit. Rev. Neurobiol. 8:1994;1-10.
    • (1994) Crit. Rev. Neurobiol. , vol.8 , pp. 1-10
    • Rothwell, N.J.1
  • 52
    • 0029900303 scopus 로고    scopus 로고
    • Degeneration and regeneration of axons in the lesioned spinal cord
    • Schwab M.E., Bartholdi D. Degeneration and regeneration of axons in the lesioned spinal cord. Physiol. Rev. 76:1996;319-370.
    • (1996) Physiol. Rev. , vol.76 , pp. 319-370
    • Schwab, M.E.1    Bartholdi, D.2
  • 53
    • 0028845771 scopus 로고
    • Experimental Listeria meningoencephalitis. Macrophage inflammatory protein-1 alpha and -2 are produced intrathecally and mediate chemotactic activity in cerebrospinal fluid of infected mice
    • Seebach J., Bartholdi D., Frei K., Spanaus K.S., Ferrero E., Widmer U., Isenmann S., Strieter R.M., Schwab M., Pfister H.et al. Experimental Listeria meningoencephalitis. Macrophage inflammatory protein-1 alpha and -2 are produced intrathecally and mediate chemotactic activity in cerebrospinal fluid of infected mice. J. Immunol. 155:1995;4367-4375.
    • (1995) J. Immunol. , vol.155 , pp. 4367-4375
    • Seebach, J.1    Bartholdi, D.2    Frei, K.3    Spanaus, K.S.4    Ferrero, E.5    Widmer, U.6    Isenmann, S.7    Strieter, R.M.8    Schwab, M.9    Pfister, H.10
  • 55
    • 0025607948 scopus 로고
    • Direct injection into the spinal cord causes autoimmune encephalomyelitis-like inflammation
    • Simmons R.D., Willenborg D.O. Direct injection into the spinal cord causes autoimmune encephalomyelitis-like inflammation. J. Neurol. Sci. 100:1990;37-42.
    • (1990) J. Neurol. Sci. , vol.100 , pp. 37-42
    • Simmons, R.D.1    Willenborg, D.O.2
  • 56
    • 0029939467 scopus 로고    scopus 로고
    • Multiple sclerosis: A coordinated immunological attack against myelin in the central nervous system
    • Steinman L. Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell. 85:1996;299-302.
    • (1996) Cell , vol.85 , pp. 299-302
    • Steinman, L.1
  • 57
    • 0025986461 scopus 로고
    • Review of experimental spinal cord injury with emphasis on the local and systemic circulatory effects
    • Tator C.H. Review of experimental spinal cord injury with emphasis on the local and systemic circulatory effects. Neurochirurgie. 37:1991;291-302.
    • (1991) Neurochirurgie , vol.37 , pp. 291-302
    • Tator, C.H.1
  • 58
    • 0027400847 scopus 로고
    • Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion
    • Taupin V., Toulmond S., Serrano A., Benavides J., Zavala F. Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. J. Neuroimmunol. 42:1993;177-186.
    • (1993) J. Neuroimmunol. , vol.42 , pp. 177-186
    • Taupin, V.1    Toulmond, S.2    Serrano, A.3    Benavides, J.4    Zavala, F.5
  • 59
    • 0027468544 scopus 로고
    • Localization of TNFα, and IL-1α immunoreactivities in striatal neurons after surgical injury to the hippocampus
    • Tchelingerian J.L., Quinonero J., Booss J., Jacque C. Localization of TNFα, and IL-1α immunoreactivities in striatal neurons after surgical injury to the hippocampus. Neuron. 10:1993;213-224.
    • (1993) Neuron , vol.10 , pp. 213-224
    • Tchelingerian, J.L.1    Quinonero, J.2    Booss, J.3    Jacque, C.4
  • 60
    • 0028982742 scopus 로고
    • Interleukin-1 receptor antagonist inhibits neuronal damage caused by percussion injury in the rat
    • Toulmond S., Rothwell N.J. Interleukin-1 receptor antagonist inhibits neuronal damage caused by percussion injury in the rat. Brain Res. 671:1995;261-266.
    • (1995) Brain Res. , vol.671 , pp. 261-266
    • Toulmond, S.1    Rothwell, N.J.2
  • 61
    • 0027453380 scopus 로고
    • Cytokine indices in Alzheimer's temporal cortex: No changes in mature IL-1 beta or IL-1RA but increases in the associated acute phase proteins IL-6, alpha 2-macroglobulin and C-reactive protein
    • Wood J.A., Wood P.L., Ryan R., Graff-Radford N.R., Pilapil C., Robitaille Y., Quirion R. Cytokine indices in Alzheimer's temporal cortex: no changes in mature IL-1 beta or IL-1RA but increases in the associated acute phase proteins IL-6, alpha 2-macroglobulin and C-reactive protein. Brain Res. 629:1993;245-252.
    • (1993) Brain Res. , vol.629 , pp. 245-252
    • Wood, J.A.1    Wood, P.L.2    Ryan, R.3    Graff-Radford, N.R.4    Pilapil, C.5    Robitaille, Y.6    Quirion, R.7
  • 62
    • 0025820808 scopus 로고
    • Detection of interleukin-1 and interleukin-6 in the adult brain, following mechanical injury, by in vivo microdialysis: Evidence for microglia in cytokine production
    • Woodroofe M.N., Sarna G.S., Wadhwa M., Hayes G.M., Loughlin A.J., Tinker A., Cuzner M.L. Detection of interleukin-1 and interleukin-6 in the adult brain, following mechanical injury, by in vivo microdialysis: evidence for microglia in cytokine production. J. Neuroimmunol. 33:1991;227-236.
    • (1991) J. Neuroimmunol. , vol.33 , pp. 227-236
    • Woodroofe, M.N.1    Sarna, G.S.2    Wadhwa, M.3    Hayes, G.M.4    Loughlin, A.J.5    Tinker, A.6    Cuzner, M.L.7
  • 63
    • 0027475987 scopus 로고
    • Secondary injury mechanisms in acute spinal cord injury
    • Young W. Secondary injury mechanisms in acute spinal cord injury. J. Emerg. Med. 11(Suppl. 1):1993;13-22.
    • (1993) J. Emerg. Med. , vol.11 , Issue.SUPPL. 1 , pp. 13-22
    • Young, W.1
  • 64
    • 0343677157 scopus 로고    scopus 로고
    • Cerebral injection of antiinflammatory cytokine IL-10 increases the size of cerebral infarcts in the rat
    • Zhai Q.H., Futrell N., Chen F.J. Cerebral injection of antiinflammatory cytokine IL-10 increases the size of cerebral infarcts in the rat. Soc. Neurosci. Abstr. 22:1996;5.
    • (1996) Soc. Neurosci. Abstr. , vol.22 , pp. 5
    • Zhai, Q.H.1    Futrell, N.2    Chen, F.J.3


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